Cten006523.1
Basic Information
- Insect
- Chironomus tentans
- Gene Symbol
- SPOPL
- Assembly
- GCA_963573255.1
- Location
- OY754303.1:13424208-13428783[+]
Transcription Factor Domain
- TF Family
- BTB
- Domain
- zf-C2H2|ZBTB
- PFAM
- PF00651
- TF Group
- Zinc-Coordinating Group
- Description
- The BTB (for BR-C, ttk and bab) [6] or POZ (for Pox virus and Zinc finger) [1] domain is present near the N-terminus of a fraction of zinc finger (Pfam:PF00096) proteins and in proteins that contain the Pfam:PF01344 motif such as Kelch and a family of pox virus proteins. The BTB/POZ domain mediates homomeric dimerisation and in some instances heteromeric dimerisation [1]. The structure of the dimerised PLZF BTB/POZ domain has been solved and consists of a tightly intertwined homodimer. The central scaffolding of the protein is made up of a cluster of alpha-helices flanked by short beta-sheets at both the top and bottom of the molecule [2]. POZ domains from several zinc finger proteins have been shown to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes including N-CoR and SMRT [5, 3, 4]. The POZ or BTB domain is also known as BR-C/Ttk or ZiN.
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 5 4e-22 3.8e-20 72.3 0.9 3 107 79 181 77 184 0.90 2 5 5.2 4.9e+02 1.1 0.0 77 108 183 214 180 216 0.84 3 5 1.5e-22 1.5e-20 73.6 1.0 7 107 294 393 288 396 0.89 4 5 2.5e-22 2.4e-20 73.0 0.2 5 107 484 584 479 587 0.86 5 5 0.67 63 4.0 0.1 78 108 587 617 584 619 0.86
Sequence Information
- Coding Sequence
- ATGGACCATAAGTGGAAAATTGACGATATAGATACACAAGCTTCATTTAAGCTATCAATAGACTTTCGATGCGAGTCATTaaatttggaTGTAACACAAAAGGATGTGTGTGAAATCTGTAAGCAGGCTCAATATGATAGAACTTCTTGTTGCAGACAATCTTCATTCGTAAAACAATTGGAAGTTAAgGCAACGGTCACTCAAAAGTGCAATCTAAAGATGGACCTACGAAACGCTCTTTTCAACAAGGAATTAAATGATTTCACTTTTGTTATTGATGAGGAGGAAATTCCTGTAAGCAGATTCATCCTGTCAGtCAGAAGTCCAGTATTTCAAAGGATGTTCAATTCTGAATTTAAGGAGAAGACTGTAGATCGATTTAATCTACAAACAAACATTCCAAAGAATGTATTCAAGGAAATGATTCGATACATTTATACTGATGAAGTACGCGAATTGAACAAACATGTATTTGACCTGCTGCATGCCTCTGATTATTACCAAATTGAATGCCTTAAGAATATTTGTGAGTGTCGTTTGCGTACGATTTTGAAGCCATCAAATGCGAATCTGATTTTTCAAAGTGCACATTTGTATCAATGCAGTAATGCTTTAAAGGAAGCAgcatttttcacaattaagcaGATCTTTAAAGCCAATAATTATACTCTACCTGAAGACTTATTCAATAATCCATCAAAAGTAGCAAAACTTTTTGAGATGAAGAAGGCATTTGAAGATGAAATTGGTACGCAAACTCCAACTAATGAGCTTGATAAAGCTTTGTCCGCTAATCAGATTAAAGCTGCATTACGTGATTATTTTGCAAGAGTCCATCACAACTGCGAACTAAAGACTGACCTGGAAAAGGCACTTTTCAACGAGAATTTGAGtgacttttcattcattgtgAACGATGAAAAAGTTCCAGTCAGCAAGTTCATTCTTTCTGCTCGAAGTCCAGTATTCGAACGGATGTTTAATTCTGAATTCAAGGAAAAGtatgaaaaggaaattgttTTGGGGATAAACATATCAACTGAAGCATTTAAGGAACTAATCCGATACATTTACATCAATGAAGCTTGTGACTTGGATAAACATGCATTTGAGTTGCTTCATGCTGCTGAATTATATCAAATCGACAGCCTAAAACGTATTTGTGAGAAGGAATTGCTTGCAATTCTAAACATTAATAATGCCAACGATATTTTCCAAGCTGCTCATTGTTATCGCTGTAGTGAGGAATTGAAAAACGCTTCTTTTGCTATTATCCAGAAAATTTTAGATTTGACCGTCAAGGATTTATGTACATATTGCAATCGAGATAAAGGTGGACGGACTAGTTGCTGTGGCTATAATAGCTGGAAAAAGGGATTGGAAATCGATatatTACAGGAAAAAACTAAAACCAAAAATGATCTCAAAATGGACCTAGAAAAAGCACTGTTTAACGAAAGTCTTAGTGACTTTTCATTCAGCTTGGACAATGAAAAGATTCCAGTCAGCAAGATCATCTTATCTGCCAGAAGTCCTGTatttaataagtttttcaACTCTGGATTtatggaaaagaaggaaaatacaTATGCTTTGCAGACAACCATTCCAAATGAAGCATTTAAGGAACTAATTCGATATATTTATACTGGCGATGTCTGCGATTTATCTAAGCATGTTTTCGAATTGCTACAAGCAGCTGACTATTATCATTTGGACGGTCTAAAGACCATATGTGAGGATCAACTGCTTTCATGCTTGACAGAAGAGAATGCAAGCAAGATTTTCCAAGCTGCTCATTTGTATCAATGTAGATTTGCGTTAAAGGAAGCTTCTTATGCTGTAATTAAACAgatttttgaagataaGAGCTACAAGCTGTCTGACGAATTCCTCTACAATCCATCAAAGATTgccaaactttttgaaaagattGAATCATTCGAAATGGAACTGGATGGTTAA
- Protein Sequence
- MDHKWKIDDIDTQASFKLSIDFRCESLNLDVTQKDVCEICKQAQYDRTSCCRQSSFVKQLEVKATVTQKCNLKMDLRNALFNKELNDFTFVIDEEEIPVSRFILSVRSPVFQRMFNSEFKEKTVDRFNLQTNIPKNVFKEMIRYIYTDEVRELNKHVFDLLHASDYYQIECLKNICECRLRTILKPSNANLIFQSAHLYQCSNALKEAAFFTIKQIFKANNYTLPEDLFNNPSKVAKLFEMKKAFEDEIGTQTPTNELDKALSANQIKAALRDYFARVHHNCELKTDLEKALFNENLSDFSFIVNDEKVPVSKFILSARSPVFERMFNSEFKEKYEKEIVLGINISTEAFKELIRYIYINEACDLDKHAFELLHAAELYQIDSLKRICEKELLAILNINNANDIFQAAHCYRCSEELKNASFAIIQKILDLTVKDLCTYCNRDKGGRTSCCGYNSWKKGLEIDILQEKTKTKNDLKMDLEKALFNESLSDFSFSLDNEKIPVSKIILSARSPVFNKFFNSGFMEKKENTYALQTTIPNEAFKELIRYIYTGDVCDLSKHVFELLQAADYYHLDGLKTICEDQLLSCLTEENASKIFQAAHLYQCRFALKEASYAVIKQIFEDKSYKLSDEFLYNPSKIAKLFEKIESFEMELDG
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -