Cleg004199.2


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Chesias legatella
Gene Symbol
Rfx2
Assembly
GCA_947359385.1
Location
OX375771.1:10420864-10440004[+]

Transcription Factor Domain

TF Family
RFX
Domain
RFX domain
PFAM
PF02257
TF Group
Basic Domians group
Description
RFX is a regulatory factor which binds to the X box of MHC class II genes and is essential for their expression. The DNA-binding domain of RFX is the central domain of the protein and binds ssDNA as either a monomer or homodimer [1]. It recognize X-boxes (DNA of the sequence 5'-GTNRCC(0-3N)RGYAAC-3', where N is any nucleotide, R is a purine and Y is a pyrimidine) using a highly conserved 76-residue DNA-binding domain (DBD) [2].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 3 1.4e-37 8.4e-34 116.1 0.0 3 78 222 297 220 298 0.97
2 3 1.8 1.1e+04 -2.8 0.0 24 33 638 647 624 655 0.70
3 3 2.2 1.4e+04 -3.2 0.1 25 34 691 700 682 707 0.74

Sequence Information

Coding Sequence
ATGTCTGAGATGGGGTTTGAAAATGTGTTCTATTTAGAGAATTTTGAGTGCGCCGGTGACGAGGTGCTGGTGGAGTCTTCGCCCCCTGCCTCCCCCGACATGGCGGCGCGCCTCGCAGCGCCCGCGCAGAGTAACGGCGGCGGCGCTGGCGGCGCGTCGCCGAGCGCTGTCCGCGAGCTCATCGTTATACCGGAACTGCCAGACTCCATACAACTGCAGCACGCCATACAACAGGTGTCGTCGAGCGCGGTGGTGAACGGCGATAGCTCCGGACAGTCCAGCCCCAACGCGGACGCGCACCACCACACATACATCACAGTCGCAAAAGTGGAACGCGAGTGGCGGCAGCGACTACACGATAACAGCGACTCTCTCAAAGTAGAGGTGCCCAGCGACTACGAAAGTGAGGGCGGCAACGGAGTCAACTACCATGTACAATATGTCACCGAACCACAGGAGATATACACGCAAGCCCACCAGCCTATGGAGAGTCTCCGCTCGTACCCGGTGTACGTGGGCGGCGGCGACGCGGACGCGGCGTGGGGCGGCGCCACCTCCGCCGACTACACCGCGTACGGAGTCGTGGTCGCCGGCGACGAGGCGGAGGCACCGGCGTCGCCCGCGACCCCGGCCGCCGCGCCGCAGCCGCCGCGCATGCCGCCCGCCACCGTGCAGTGGCTGCTCGACCACTACGAGACTGCTGAAGGCGTGTCGCTACCTCGGTCGACGCTGTACGCGCACTACCTGCGGCACTGCTCGACGCACCACCTGGAGCCGGTGAACGCGGCCTCCTTCGGTAAACTGATTCGGTCCGTGTTCGTGGGGCTGCGCACGCGCCGCCTCGGCACCAGGGGCAACTCCAAGTACCACTACTACGGGATCCGAGCCAAGCCCAGCGCGGATAGCGCGCCCGACGCTAACGACAGCGCCGACGATAACGCCGATATCAATGAGAAACACGAGGAGCGCGAACGTCCGCGCTCCCGGTCGGAGGGTTCGGGCTCCCCACTGGGCGCAGCCGCGGTCGCGCACCGGCAGTACCTCGCGGCGGTGTCGGCGCCCTCCCCGCCGCCGCCGCCGCCCGCCCTCGACACCGACCTCGCGGACGAGATCCCGCCCGCCGCGCTGCACGCGCTCCACAACCACCACCGCGAACACGGCGCTATGTTCCTGGAGGCGGTGGCGGCGCTGGACACGGGCGCGGTGGAGGCGGCGCGCCGCGCGTTCTGGCGGCGCAGCTCCGACGACGAGGTGCTGTGCCGGCGCACGCTGGCGCGGCTCTGCGCGCGCCGGGACGTGTGCCGCTGGCTGCGCGCCGCCGACACGCAGCTCTACCAGCGCGCGGTCGACATGCTGCTGCCCGACGTGCTGCGTCCCATCCCGCCGCAACTCACACAGTCGATCCGCAACTTCGCTAAGAGCGTGGAGTGCGCGGTGTCGGCGGGGTCGGGCGGCGCGCCGCTGCCGGCGGTGCGGGCGCAGGCGCGCGCCGCCGCCGCGCTCGCGGGCGCGCTGCGGCGCTACACCTCGCTCAACCACCTCGCGCAGGCCGCGCGCGCCGTGCTCGCCAACCATCATCAGATACATCAGATGGTGTCAGACCTGAACCGCGTGGATTTCCGCGTGGTGCGCGAGCAGGCGTCCTGGGCGTGCGCGTGCGCCTCCGCCTCCGTTGCGCTCAAACTCGAGGCTGACTTCAAGGCGACGCTGGGGCGCGGCGCTTCGCTGGAGCAGTGGGCGGCGTGGCTGGAGCGCTGCGTGGGCGGGGCGCTCGCGCCGCACGAGGGCAAGCCCGACTACGTGTCGCGCGCGCGCCGGCTGCTGCTCGACTGGTCCTTCTACTCCTCGCTCGTCATACGCGAACTCACGCTCAGATCGGCTGCGTCGTTCGGTTCGTTCCACCTGATCCGTCTGCTGTACGACGAGTACGTGTCGTACCTGATAGAGCGGCGCGTCGCGGCGCAGCTGCGGGCGCCGCCCATCGCGGTCATGCACCGCGCGCAGGTATCTGCGGGCGCCGCCCATCGCGGTCATGCACCGCGCGCAGGTATGTACCACCTGATCCGTCTGTTGTACGACGAGTACGTGTCGTACCTGATCGAGCGGCGCGTCGCGGCGCAGCTGCGGGCGCCGCCCATCGCGGTCATACACCGCGCGCAGGAGGAGGAGGATGACGAGGAGGGGCGGGAGAGCCGAGTGGAGGGCCTCGAGGAGGACCAGGACTGGGACTGGGAGGACGAGGACGACGAGGACGAGCCTGACCCCAAGAAACAGAAACTCAACGGTGAATAG
Protein Sequence
MSEMGFENVFYLENFECAGDEVLVESSPPASPDMAARLAAPAQSNGGGAGGASPSAVRELIVIPELPDSIQLQHAIQQVSSSAVVNGDSSGQSSPNADAHHHTYITVAKVEREWRQRLHDNSDSLKVEVPSDYESEGGNGVNYHVQYVTEPQEIYTQAHQPMESLRSYPVYVGGGDADAAWGGATSADYTAYGVVVAGDEAEAPASPATPAAAPQPPRMPPATVQWLLDHYETAEGVSLPRSTLYAHYLRHCSTHHLEPVNAASFGKLIRSVFVGLRTRRLGTRGNSKYHYYGIRAKPSADSAPDANDSADDNADINEKHEERERPRSRSEGSGSPLGAAAVAHRQYLAAVSAPSPPPPPPALDTDLADEIPPAALHALHNHHREHGAMFLEAVAALDTGAVEAARRAFWRRSSDDEVLCRRTLARLCARRDVCRWLRAADTQLYQRAVDMLLPDVLRPIPPQLTQSIRNFAKSVECAVSAGSGGAPLPAVRAQARAAAALAGALRRYTSLNHLAQAARAVLANHHQIHQMVSDLNRVDFRVVREQASWACACASASVALKLEADFKATLGRGASLEQWAAWLERCVGGALAPHEGKPDYVSRARRLLLDWSFYSSLVIRELTLRSAASFGSFHLIRLLYDEYVSYLIERRVAAQLRAPPIAVMHRAQVSAGAAHRGHAPRAGMYHLIRLLYDEYVSYLIERRVAAQLRAPPIAVIHRAQEEEDDEEGRESRVEGLEEDQDWDWEDEDDEDEPDPKKQKLNGE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
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