Cleg004548.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Chesias legatella
Gene Symbol
-
Assembly
GCA_947359385.1
Location
OX375783.1:4459882-4467198[-]

Transcription Factor Domain

TF Family
bHLH
Domain
HLH domain
PFAM
PF00010
TF Group
Basic Domians group
Description
A basic helix-loop-helix (bHLH) is a protein structural motif that characterizes one of the largest families of dimerizing transcription factors.It should not be confused with the helix-turn-helix domain.The motif is characterized by two α-helices connected by a loop. In general, transcription factors including this domain are dimeric, each with one helix containing basic amino acid residues that facilitate DNA binding. In general, one helix is smaller, and, due to the flexibility of the loop, allows dimerization by folding and packing against another helix. The larger helix typically contains the DNA-binding regions. bHLH proteins typically bind to a consensus sequence called an E-box, CANNTG. The canonical E-box is CACGTG (palindromic), however some bHLH transcription factors, notably those of the bHLH-PAS family, bind to related non-palindromic sequences, which are similar to the E-box. bHLH TFs may homodimerize or heterodimerize with other bHLH TFs and form a large variety of dimers, each one with specific functions.https://en.wikipedia.org/wiki/Basic_helix-loop-helix
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 46 0.11 34 4.4 1.3 10 35 120 147 115 159 0.64
2 46 0.057 18 5.3 0.9 10 44 142 179 138 185 0.62
3 46 0.059 19 5.2 1.0 10 44 164 201 160 207 0.62
4 46 0.056 18 5.3 1.0 10 44 186 223 181 229 0.63
5 46 0.093 30 4.6 1.8 9 44 207 245 200 251 0.64
6 46 0.055 18 5.3 0.9 10 44 230 267 226 273 0.62
7 46 0.06 19 5.2 1.0 10 44 252 289 248 295 0.62
8 46 0.26 83 3.2 4.8 8 29 294 317 270 340 0.55
9 46 0.05 16 5.4 1.4 10 46 318 357 314 364 0.65
10 46 0.37 1.2e+02 2.7 4.2 14 46 344 379 336 400 0.55
11 46 0.083 26 4.7 2.8 9 49 383 426 376 430 0.69
12 46 0.079 25 4.8 1.1 10 35 406 433 402 445 0.65
13 46 0.072 23 4.9 1.0 10 43 428 464 424 471 0.61
14 46 0.036 12 5.9 1.4 10 49 450 492 446 496 0.67
15 46 0.57 1.8e+02 2.1 5.8 13 46 475 511 464 537 0.52
16 46 0.053 17 5.4 1.1 10 43 516 552 512 559 0.63
17 46 0.074 23 4.9 1.0 10 43 538 574 534 581 0.61
18 46 0.043 14 5.7 1.3 10 48 560 601 556 604 0.66
19 46 0.074 24 4.9 1.0 10 35 582 609 578 621 0.65
20 46 0.085 27 4.7 1.1 10 43 604 640 601 647 0.59
21 46 0.064 20 5.1 0.8 10 43 626 662 622 668 0.61
22 46 0.1 32 4.5 1.1 10 35 648 675 644 687 0.63
23 46 0.33 1.1e+02 2.8 4.2 10 46 670 709 666 729 0.58
24 46 0.096 31 4.5 1.1 10 35 714 741 710 753 0.63
25 46 0.074 24 4.9 1.5 10 45 736 774 732 780 0.63
26 46 0.068 22 5.0 1.0 10 43 758 794 753 800 0.62
27 46 0.045 14 5.6 1.5 10 48 780 821 775 824 0.67
28 46 0.053 17 5.4 1.5 10 46 802 841 798 848 0.65
29 46 0.088 28 4.7 1.1 10 43 824 860 821 867 0.59
30 46 0.058 19 5.2 1.0 10 44 846 883 842 889 0.62
31 46 0.049 16 5.5 1.1 10 46 868 907 865 911 0.63
32 46 0.046 15 5.6 0.9 10 43 890 926 886 933 0.63
33 46 0.21 67 3.4 0.5 10 28 912 930 909 942 0.75
34 46 0.039 12 5.8 1.5 10 49 934 976 930 980 0.67
35 46 0.093 30 4.6 1.0 9 34 955 979 952 994 0.70
36 46 0.12 38 4.2 1.0 10 35 978 1005 974 1017 0.63
37 46 0.23 74 3.3 0.4 8 28 998 1018 992 1024 0.83
38 46 0.063 20 5.1 0.8 10 43 1022 1058 1018 1064 0.61
39 46 0.091 29 4.6 1.0 10 35 1044 1071 1040 1083 0.63
40 46 0.16 51 3.8 2.0 9 35 1065 1093 1058 1105 0.66
41 46 0.089 28 4.6 1.0 10 35 1088 1115 1083 1127 0.64
42 46 0.065 21 5.1 1.3 10 45 1110 1148 1106 1154 0.63
43 46 0.093 30 4.6 1.0 10 35 1132 1159 1128 1171 0.63
44 46 0.072 23 4.9 1.5 10 45 1154 1192 1150 1198 0.63
45 46 0.11 34 4.4 2.0 9 44 1175 1213 1168 1219 0.64
46 46 0.11 36 4.3 0.1 9 33 1219 1243 1216 1248 0.81

Sequence Information

Coding Sequence
ATGAAAAAGTTTAAACGGCCAGCCAGGAGACCAGGTCCAGTCCAGGAGGATTCATCGGATAATTCAGATTCTACTGAAGCACCAACACAACCCAAAAAGGCAAAATTGAAGAGGAAGAAATCATTAACACCAGCAGAATCTGGACTTCATTCAGGGGCGGATGAGGCACCAACCCAACCCATAAAAAAGGGCAAACCACAGGAAAAGAGATTGAAACCAAAAGTAGGAGATAAACCAATTTCTGATTCTGATGAGCAACAAACACATAACAAAGGAAATGGCAGAGGAAAAGCCAAGAAGTCATCCAAAGCCCCAGAACCCATGGAAGAATCTTCAAATGATTCAGTAGCAATCAACAGGCAACACCTACGCAAGATCAACACCACCCTGGATACTCTACGCAATATAATAGTAGCAATCAACAGGCAACACCTACGCAAGATCAACACCACCCTGGATACTCTACGCAATATAATAGTAGCAATCAACAGGCAACACCTACGCAAGATCAACACCACCCTGGATACTCTACGCAATATAATAGTAGCAATCAACAGGCAACACCTACGCAAGATCAACACCACCCTGGATACTCTACGCAATATAATAGTAGCAATCAACAGGCAACACCTACGCAAGATCAACACCACCCTGGATACTCTACGCAATATAATAGTAGCAATCAACAGGCAACACCTACGCAAGATCAACACCACCCTGGATACTCTACGCAATATAATAGTAGCAATCAACAGGCAACACCTACGCAAGATCAACACCACCCTGGATACTCTACGCAATATAATAGTAGCAATCAACAGGCAACACCTACGCAAGATCAACACCACCCTGGATACTCTACGCAATATAATAGTAGCAATCAACAGGCAACACCTACGCAAGATCAACACCACCCTGGATACTCTACGCAATATAATAGTAGCAATCAACAGGCAACACCTACGCAAGATCAACACCACCCTGGATACTCTACGCAATATAATAGCGTCAATCAACAGGCAACACCTACGCAAGATCAACACCACCCTGGATACTCTACGCAATATAATAGTAGCAATCAACAGGCAACACCTACGCAAGATCAACACCACCCTGGATACTCTACGCAATATAATAGTAGCAATCAACAGGCAACACCTACGCAAGATCAACACCACCCTGGATACTCTACGCAATATAATAGTAGCAATCAACAGGCAACACCTACGCAAGATCAACACCACCCTGGATACTCTACGCAATATAATAGCGTCAATCAACAGGCAACACCTACGCAAGATCAACACCACCCTGGATACTCTACGCAATATAATAGTAGCAATCAACAGGCAACACCTACGCAAGATCAACACCACCCTGGATACTCTACGCAATATAATAGTAGCAATCAACAGGCAACACCTACGCAAGATCAACACCACCCTGGATACTCTACGCAATATAATAGCGTCAATCAACAGGCAACACCTACGCAAGATCAACACCACCCTGGATACTCTACGCAATATAATAGTAGCAATCAACAGGCAACACCTACGCAAGATCAACACCACCCTGGATACTCTACGCAATATAATAGCGTCAATCAACAGGCAACACCTACGCAAGATCAACACCACCCTGGATACTCTACGCAATATAATAGTAGCAATCAACAGGCAACACCTACGCAAGATCAACACCACCCTGGATACTCTACGCAATATAATAGTAGCAATCAACAGGCAACACCTACGCAAGATCAACACCACCCTGGATACTCTACGCAATATAATAGCGTCAATCAACAGGCAACACCTACGCAAGATCAACACCACCCTGGATACTCTACGCAATATAATAGTAGCAATCAACAGGCAACACCTACGCAAGATCAACACCACCCTGGATACTCTACGCAATATAATAGTAGCAATCAACAGGCAACACCTACGCAAGATCAACACCACCCTGGATACTCTACGCAATATAATAGTAGCAATCAACAGGCAACACCTACGCAAGATCAACACCACCCTGGATACTCTACGCAATATAATAGTAGCAATCAACAGGCAACACCTACGCAAGATCAACACCACCCTGGATACTCTACGCAATATAATAGTAGCAATCAACAGGCAACACCTACGCAAGATCAACACCACCCTGGATACTCTACGCAATATAATAGTAGCAATCAACAGGCAACACCTACGCAAGATCAACACCACCCTGGATACTCTACGCAATATAATAGTAGCAATCAACAGGCAACACCTACGCAAGATCAACACCACCCTGGATACTCTACGCAATATAATAGTAGCAATCAACAGGCAACACCTACGCAAGATCAACACCACCCTGGATACTCTACGCAATATAATAGTAGCAATCAACAGGCAACACCTACGCAAGATCAACACCACCCTGGATACTCTACGCAATATAATAGCGTCAATCAACAGGCAACACCTACGCAAGATCAACACCACCCTGGATACTCTACGCAATATAATAGTAGCAATCAACAGGCAACACCTACGCAAGATCAACACCACCCTGGATACTCTACGCAATATAATAGTAGCAATCAACAGGCAACACCTACGCAAGATCAACACCACCCTGGATACTCTACGCAATATAATAGTAGCAATCAACAGGCAACACCTACGCAAGATCAACACCACCCTGGATACTCTACGCAATATAATAGCGTCAATCAACAGGCAACACCTACGCAAGATCAACACCACCCTGGATACTCTACGCAATATAATAGTAGCAATCAACAGGCAACACCTACGCAAGATCAACACCACCCTGGATACTCTACGCAATATAATAGTAGCAATCAACAGGCAACACCTACGCAAGATCAACACCACCCTGGATACTCTACGCAATATAATAGCGTCAATCAACAGGCAACACCTACGCAAGATCAACACCACCCTGGATACTCTACGCAATATAATAGTAGCAATCAACAGGCAACACCTACGCAAGATCAACACCACCCTGGATACTCTACGCAATATAATAGTAGCAATCAACAGGCAACACCTACGCAAGATCAACACCACCCTGGATACTCTACGCAATATAATAGTAGCAATCAACAGGCAACACCTACGCAAGATCAACACCACCCTGGATACTCTACGCAATATAATAGTAGCAATCAACAGGCAACACCTACGCAAGATCAACACCACCCTGGATACTCTACGCAATATAATAGTAGCAATCAACAGGCAACACCTACGCAAGATCAACACCACCCTGGATACTCTACGCAATATAATAGTAGCAATCAACAGGCAACACCTACGCAAGATCAACACCACCCTGGATACTCTACGCAATATAATAGTAGCAATCAACAGGCAACACCTACGCAAGATCAACACCACCCTGGATACTCTACGCAATATAATAGTAGCAATCAACAGGCAACACCTACGCAAGATCAACACCACCCTGGATACTCTACGCAATATAATAGTAGCAATCAACAGGCAACACCTACGCAAGATCAACACCACCCTGGATACTCTACGCAATATAATAGTAGCAATCAACAGGCAACACCTACGCAAGATCAACACCACCCTGGATACTCTACGCAATATAATAGTAGCAATCAACAGGCAACACCTACGCAAGATCAACACCACCCTGGATACTCTACGCAATATAATAGTAGCAATCAACAGGCAACAACATCTATACCATCAACTTCATCTCAGTCATCGAATCCGATTCCAGCTTCGCCATCAGCATCTAGTAATCATTCCATACATTCCCAAGACTCAGATTACTTAG
Protein Sequence
MKKFKRPARRPGPVQEDSSDNSDSTEAPTQPKKAKLKRKKSLTPAESGLHSGADEAPTQPIKKGKPQEKRLKPKVGDKPISDSDEQQTHNKGNGRGKAKKSSKAPEPMEESSNDSVAINRQHLRKINTTLDTLRNIIVAINRQHLRKINTTLDTLRNIIVAINRQHLRKINTTLDTLRNIIVAINRQHLRKINTTLDTLRNIIVAINRQHLRKINTTLDTLRNIIVAINRQHLRKINTTLDTLRNIIVAINRQHLRKINTTLDTLRNIIVAINRQHLRKINTTLDTLRNIIVAINRQHLRKINTTLDTLRNIIVAINRQHLRKINTTLDTLRNIIASINRQHLRKINTTLDTLRNIIVAINRQHLRKINTTLDTLRNIIVAINRQHLRKINTTLDTLRNIIVAINRQHLRKINTTLDTLRNIIASINRQHLRKINTTLDTLRNIIVAINRQHLRKINTTLDTLRNIIVAINRQHLRKINTTLDTLRNIIASINRQHLRKINTTLDTLRNIIVAINRQHLRKINTTLDTLRNIIASINRQHLRKINTTLDTLRNIIVAINRQHLRKINTTLDTLRNIIVAINRQHLRKINTTLDTLRNIIASINRQHLRKINTTLDTLRNIIVAINRQHLRKINTTLDTLRNIIVAINRQHLRKINTTLDTLRNIIVAINRQHLRKINTTLDTLRNIIVAINRQHLRKINTTLDTLRNIIVAINRQHLRKINTTLDTLRNIIVAINRQHLRKINTTLDTLRNIIVAINRQHLRKINTTLDTLRNIIVAINRQHLRKINTTLDTLRNIIVAINRQHLRKINTTLDTLRNIIASINRQHLRKINTTLDTLRNIIVAINRQHLRKINTTLDTLRNIIVAINRQHLRKINTTLDTLRNIIVAINRQHLRKINTTLDTLRNIIASINRQHLRKINTTLDTLRNIIVAINRQHLRKINTTLDTLRNIIVAINRQHLRKINTTLDTLRNIIASINRQHLRKINTTLDTLRNIIVAINRQHLRKINTTLDTLRNIIVAINRQHLRKINTTLDTLRNIIVAINRQHLRKINTTLDTLRNIIVAINRQHLRKINTTLDTLRNIIVAINRQHLRKINTTLDTLRNIIVAINRQHLRKINTTLDTLRNIIVAINRQHLRKINTTLDTLRNIIVAINRQHLRKINTTLDTLRNIIVAINRQHLRKINTTLDTLRNIIVAINRQHLRKINTTLDTLRNIIVAINRQHLRKINTTLDTLRNIIVAINRQQHLYHQLHLSHRIRFQLRHQHLVIIPYIPKTQIT

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-