Basic Information

Insect: Cheilosia vernalis
Gene Symbol: RREB1
Assembly: GCA_949126925.1
Location: OX421360.1:38624052-38629849[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 0.034 4.3 8.8 0.8 1 21 237 257 237 259 0.93

2 14 0.00032 0.04 15.2 0.2 1 23 269 291 269 291 0.98

3 14 9.1e-06 0.0012 20.0 5.2 1 23 297 319 297 319 0.98

4 14 0.03 3.8 8.9 2.8 2 19 530 547 530 547 0.97

5 14 3.5 4.4e+02 2.5 0.4 1 19 593 611 593 614 0.79

6 14 0.0085 1.1 10.7 0.1 1 23 767 789 767 789 0.97

7 14 0.00017 0.022 16.0 1.7 1 23 798 820 798 820 0.99

8 14 0.00044 0.056 14.7 2.0 1 23 826 849 826 849 0.97

9 14 0.00091 0.11 13.8 2.1 1 23 1194 1217 1194 1217 0.95

10 14 8.2e-05 0.01 17.0 0.3 2 23 1524 1545 1523 1545 0.97

11 14 0.14 17 6.9 6.3 1 23 1551 1574 1551 1574 0.97

12 14 2.9 3.6e+02 2.7 6.3 1 23 1665 1687 1665 1688 0.95

13 14 0.008 1 10.8 0.5 3 23 1737 1757 1735 1757 0.96

14 14 0.0013 0.17 13.2 4.8 1 23 1763 1785 1763 1785 0.99

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	0.034	4.3	8.8	0.8	1	21	237	257	237	259	0.93
2	14	0.00032	0.04	15.2	0.2	1	23	269	291	269	291	0.98
3	14	9.1e-06	0.0012	20.0	5.2	1	23	297	319	297	319	0.98
4	14	0.03	3.8	8.9	2.8	2	19	530	547	530	547	0.97
5	14	3.5	4.4e+02	2.5	0.4	1	19	593	611	593	614	0.79
6	14	0.0085	1.1	10.7	0.1	1	23	767	789	767	789	0.97
7	14	0.00017	0.022	16.0	1.7	1	23	798	820	798	820	0.99
8	14	0.00044	0.056	14.7	2.0	1	23	826	849	826	849	0.97
9	14	0.00091	0.11	13.8	2.1	1	23	1194	1217	1194	1217	0.95
10	14	8.2e-05	0.01	17.0	0.3	2	23	1524	1545	1523	1545	0.97
11	14	0.14	17	6.9	6.3	1	23	1551	1574	1551	1574	0.97
12	14	2.9	3.6e+02	2.7	6.3	1	23	1665	1687	1665	1688	0.95
13	14	0.008	1	10.8	0.5	3	23	1737	1757	1735	1757	0.96
14	14	0.0013	0.17	13.2	4.8	1	23	1763	1785	1763	1785	0.99

Sequence Information

Coding Sequence: ATGTTGAAAACGCcaattaaaaagcaattaaCCGACATTCCACTGCGCAAAATGGATCGACGCGACTCAACAACATCGGACTCATCTGTCGAACCCATGGACTTGGGACGTACACCAGAAACTAAAAAACAAACCAACACAGCAGCATTACAGATGCCAACTGCAGTAACACTTAAAGATGCCATTTTATCAGATGCCAATACAAAACACCCCATACGTCATGAATCTGATGCCGACGAATCAGATGAGAAAGACAGAGATCACCATCAGCGGCGATCACACAGTCAACATCACTACCATCATCGTCGGCGCGGTGGCAATAGTGGACGCGATAAACGAACCGTCCACTTGGAATGCACCGACACTCCACATTCGTTGCGAAAGAAATTTCGATTCAGCAGCACGCAAAACCCATTGGTTCCAGAGACTGTGATCAATTTGAAACAACAGAAAACATCGAACAATGATTCCACGTTATCGGGGAAGTCAGCAAATCTAACCGCTACAACGAACAACAATGAATCTGGCTTTGTGGATGCCAGCAGCAGTCATGTTCTAAACACATCCGCTTCATCGGCGACATCATccacatcgtcatcatcatcgtcttcgCCGACATCGTCATCGTCGGCGGCGGCGTCACCATCCGCCAGTAATATCGCCGTTTCGAGTCCCGAATCGGGCGTGGGCGAACGTGACGACATGAAGTACCTTTGCCCAATTTGTGAGGTGGTATCGGCGACACCGCATGAATTTACCAATCACATCAGATGTCATAATTATTCATCTGGGGACACCGAAAATTTCACCTGCCGCATTTGCTCTAAGGTTCTATCATCTGCCTCGTCATTGGATCGACACGTTCTGGTGCACACTGGTGAACGGCCCTTCAACTGCAAATATTGCCAACTGACATTCACCACAAATGGGAACATGCATCGTCACATGCGAACCCACAAACAGCACCAGCAACACTATCATCGAAATTCAAATGGTACAAAGGGGGGTGGaagtggcggtggtggtggtgcaaCGATTGCGGGTGCTAATGGCGGCAGCTCCGTCCTAACACCAAATTTACAACCAAACGACCAATCGGCTGCTGTGCCCTCCAAACCAACTATCGTTACCAATGGTGTCGTTATTAACAGCAATGGTGACACAATtggaggaggaggaggtggtggtggtggtggcgaaAGTTACGAAAGTGATGGTGGTTGCTCAACGGATTCATCAAGTGCCATCAGCCAAAGTtccaataacaataacaacagcaatacgaacaacaAAAACATTAGTAATTTTAAGCGCAAGAGCACCGACAGCTTGGATGACATGGCCATGATGAAGCGACGCGTGAAGACgaccatcaacaacaacaatatcaTCGATAACAACATGCACACCGCCACGGAAAGGAGTACGATCGAAGAGGCTGACGAAGACTTGAAGCAGCAacaccagcaacaacaacaacaacaacaacaacaaaagctcTTTTGCCCGGTATGCAATCGCAGTGACTTTGTGGGGATGCTGGCATTGGGCTCCCATATGGACTGCGATCATTCGGATATCCCCGCAAAATGCCGTCATTGTGACGTTGTTTTCAAGACACACAAGCAACTGAACGTACATCCGTGCACGAGTAAGCTTAAGATCACGCACGGTTTTAAGGATCTTACGTTTGTGGACTTTTCGAGCGAAAAGTTCCCCCTCATTGCCAAGTCTTTATGTGAGCAGAGCCTGAGGACGTCAGTGGGTAGTCAAAAGTTTGAGTGCTCCAAGTGCTATCGAGCATTTCCGTGCGCCAGTGCTGTGGAAATACACGAAAAGGAGTGCGCCACATCAGGGATGAATTTGTTCGTCGATGCACATGATTTCTCCATTCGCAAGCAGCGATCGTATAGCGAGAGCTCAGGTGGCGCTGACGATGACGATAATCGGCGGGAGGAGTTCTTCGCCCGTTTGTACTTAAAGAACAAATCTACAGTACAAAGCATGACCAGCTTGTCGTTATCGTCCCCCTCGCTGTCTGATATTAAGTCGTCCGAGTTGGACAAGACACCTGTAAAAATGTCCCAATCGCAGCTCGATCAATACCACGACACTAAAGAGCTGGCCGACATTCAATCCATTCTCAACATAACTTCATCTTCATCAACGAGCAATTTCCTTCGGAACTTTGAAAACTCTGTGAATACACCGATCAGTAATTACGGAACCGAAAATGGCGAAGAGGAAGCCCAAGATGCATTCACCTCCGAGTTTCGCAAGATGAAGTTGCGCGGGGAGTTCCCCTGTAAGCTGTGCACGGCAGTGTTTCCCAACCTTCGAGCTTTAAAGGGCCACAATCGCATACATCTGAGTGCAGCCGGTCCCGGTCCATATCGCTGCAATATGTGCACATATTCAATCCATGATAAGGCGGCGCTGGTGCGTCATATGCGAACACACAACGGCGACAGGCCGTACGAGTGCGCCATCTGTAACTATGCATTCACAACCAAAGCCAACTGTGAACGACATTTGCGCAATCGGCACGCCAAAACCACACGCGACGATGTAAAGCGCGCTATTATCTACCACCCATCGGAAGACTCGAACTGCGATGACGCCATGAAGAAGCTGCACATGTTCTCCTCGCCGGAATTTGATCAAGACGacatggagcaacaccatccaCCAAAGGACCGATCCACTCCGGTATCACATCTGAAGGAAATGCTCCAGTCCGAGTCGAAGCCGCTCAAGATTCAAGTGAAGAGCTTGGAGAAGTTGATAGAGAAGGCGGCACCATCGTTTAATCAATCAGATGAGATCGAAAAGGAGCTGGAACGAGATGATGTCCAACACGATAAAGCCAGTCGACCGATGGATCTTAGCATGGATGCATTGGATTTGAGCAAAAAGCCCTTGAAAGCACTTAAAGTTCCAGAAAAACCACCACAATCTCCCATACCGCCTCAAATACCACCTGGGCGTGCACAACCCGAAGAGCAAAACATCGACATGCATCTTTTGGAGAACAACCAACAGTTGCTGCTGGCCCAGCAGCGATTGTTGAACGCAGCTATGCCGAAAATGGATCCCGCGCACTATTTGCAGCTCTCGCAGCTCTACCGCAACTTGGTGCTGCAGCCATTTCACCCGTTTTTCCTGCAAAACTCGTTCCTATCGAACAATATCAGTGATCTAAATAAATTCGCTCCGCTGATGAATCCACTCTTTGATCATCCCGCAGCCTCTGAGACCTTCGCCGCCGGAAACTATAACCAAAGTATGCAGCCAAAGATAGTACCAGAAGAAGCCAACTTATTGCTGAAGCAGTCCAATTCCCGGGCTCACTCCCCGAGCCCGGCTAAGAACCAATTAATACCGCGGAACCTCACTCCATCATCGACACAGATGCAACCCATGCAACGAAGCCATCCGCATATGGGTCCCATGACGGGACCACATTCTACAGGAATGATCCCATCATCGGTGTCCAATACAGGTCCAGTGAAGATGGTCATTAAGAACGGTGTACTCATGCCCAAGCAGAAGCAGCGTCGTTATCGCACCGAACGCCCCTTTGCTTGTGAACACTGCTCCGCTCGCTTCACCTTGCGTTCGAATATGGAGCGCCATATCAAACAACAGCACCCCCAGTATTGGGCTCAACGACAACGTAGCGGTCACCACATCATGCGTGGGCGTGCCAATAGTAGTTCGGTCCTCTCGCACATGCAGCCGAATCACTCGCCCTTGGAAGCTCCACATCAGATTAACCACAGTGGCATAATCAATCACATGAGCGCTATCCCCGATCAGGTAAAATATGCCATTCTCGCCAAACAGCTCAAGGCCCGCAAGGAGACAGACATTCTGCAGCAAGCCCTGTCCCAAGGCTCTAACAGTGTGTTAACACAGACCCCAAACACCGCCGCCATCACTAATCTTCGAAAATCACTCAGCTCCTCGTCGAATACAAATAATGGCAGCATAGAGGACGATGATCCCAAGCTCGTTATCGACGAGGACGACGAAAAGGAAGACGATCacgaggatgatgatgatgatgaagaagaGGAAGATTGTAAGGCAGAAAATTTGACGCAAATACAAGGCTACCAAGAAATCAATGAAGCTGCAAAAAAAGCTGCCAAGTCAATTTTGGAGCAGGCCATGAAAGCTGGCAACACCAAAAGCTCCTTCAACCCGAATGGCAACGATATGGAAACTCCCGTTGTGAAGGACTTCAGCCTCAAACTGTCGAAAAATATGATTGCTCAAGCAGAGTCCGTTGGCAAATTCCTCAAGGAAGTCGCCAGTTCTCCGTTCAAGGATGAATCCAATGACCTCGCTTCGGTGTCAAGACTCGTTGACAACGCCACCAATGCGATGTCTTTCAACAACTACTTTCGGCCCAGTGATGTTGTGAATCAAGCGGAACAAAGTGACGAAGAGGGTTTAGTTGCATCGGGCAGCGCATCCGAAAGCAATAATTCTGGCCCCGAGGATATGCCCGGCGCGCTGGAACCAAAGAAGAAATCTGCCTACAGCTCGGCGCCAAATCGAGTGTCTTGCCCCTATTGCCAGCGAATGTTCCCCTGGTCTAGTTCACTGCGGCGACACATTCTAACACACACCGGTCAGAAGCCCTTTAAATGTTCACATTGCCCGTTGCTTTTCACCACAAAGAGCAACTGCGATCGTCACCTACTTCGAAAGCACGGTAATGTCGAATCGGCTGTGTCGTTGTATGTCCCGATCGAGGATGTAAATGAGCCATTGCCAGTTCCCAAGTCAGTCGAGGAGATTGAGctgcaacaccaacaacagctTCAGCAGcagagagaacaaaaaaaactcgAAGAACAAAAAGAGCTGGAAGAACAGAAACAAGTGGTTCAGGAGAATAATGAACAGGCAACCCCAACGACCATAAACGCGGGTTGCAAAGTAGAGCCAGTGCCACAAATTGTCTCATCGTCCGAGCTGCCGTTCAAGTGTCACCTGTGCGACAGTTCTTTTGCCGAACGTTTTCAGTGCCTCGATCATATTAAGATCCACCATGCTCAGGAGTTCGCCCTACTGCTTTCCAAGGGGGCCATTGACAGCGAAGCCGATGTCAACAGCCAAGTACAGTCAACCGAGGACGACGAAAAACGAGATGAAAGCCGCGGCAAATACCCCGACTATACCAACCGCAAGGTTATCTGCGCCTTCTGCGTTCGTCGTTTCTGGTCTACGGAAGATCTGCGTCGTCATATGCGAACTCATTCGGGCGAAAGGCCATTTCAGTGCGACATCTGCCTGCGCAAGTTCACCCTGAAGCACAGCATGCTACGACACATGAAGAAACACAGCGGCGGCAGTCATTCTAGTAACGGTGCCGCCAACGCCGCCAACAGTGGTTCCGACATATCCGACGATGAACAGCCCCCAGCCAGTGTTATGCTGGCAAGCACTCTTCGCAACCACAAAATCCAGGAGCTCTTTTCGAAGGCGAACAGCGAGTGGCGCAACAATCGACTCTCGGGCGAGCACAAGGAGAACATCGAAGAGCACAACAACCAGTCCGATCTAATTGGCAACCTGCTTGGCATCAGCGACCAGGGCATCCTCAACAAGCTTCTCTCGTCGGCGGATGAGGCGGCCAAGTTTTTAGGTGTCGACAAGTAA
Protein Sequence: MLKTPIKKQLTDIPLRKMDRRDSTTSDSSVEPMDLGRTPETKKQTNTAALQMPTAVTLKDAILSDANTKHPIRHESDADESDEKDRDHHQRRSHSQHHYHHRRRGGNSGRDKRTVHLECTDTPHSLRKKFRFSSTQNPLVPETVINLKQQKTSNNDSTLSGKSANLTATTNNNESGFVDASSSHVLNTSASSATSSTSSSSSSSPTSSSSAAASPSASNIAVSSPESGVGERDDMKYLCPICEVVSATPHEFTNHIRCHNYSSGDTENFTCRICSKVLSSASSLDRHVLVHTGERPFNCKYCQLTFTTNGNMHRHMRTHKQHQQHYHRNSNGTKGGGSGGGGGATIAGANGGSSVLTPNLQPNDQSAAVPSKPTIVTNGVVINSNGDTIGGGGGGGGGGESYESDGGCSTDSSSAISQSSNNNNNSNTNNKNISNFKRKSTDSLDDMAMMKRRVKTTINNNNIIDNNMHTATERSTIEEADEDLKQQHQQQQQQQQQQKLFCPVCNRSDFVGMLALGSHMDCDHSDIPAKCRHCDVVFKTHKQLNVHPCTSKLKITHGFKDLTFVDFSSEKFPLIAKSLCEQSLRTSVGSQKFECSKCYRAFPCASAVEIHEKECATSGMNLFVDAHDFSIRKQRSYSESSGGADDDDNRREEFFARLYLKNKSTVQSMTSLSLSSPSLSDIKSSELDKTPVKMSQSQLDQYHDTKELADIQSILNITSSSSTSNFLRNFENSVNTPISNYGTENGEEEAQDAFTSEFRKMKLRGEFPCKLCTAVFPNLRALKGHNRIHLSAAGPGPYRCNMCTYSIHDKAALVRHMRTHNGDRPYECAICNYAFTTKANCERHLRNRHAKTTRDDVKRAIIYHPSEDSNCDDAMKKLHMFSSPEFDQDDMEQHHPPKDRSTPVSHLKEMLQSESKPLKIQVKSLEKLIEKAAPSFNQSDEIEKELERDDVQHDKASRPMDLSMDALDLSKKPLKALKVPEKPPQSPIPPQIPPGRAQPEEQNIDMHLLENNQQLLLAQQRLLNAAMPKMDPAHYLQLSQLYRNLVLQPFHPFFLQNSFLSNNISDLNKFAPLMNPLFDHPAASETFAAGNYNQSMQPKIVPEEANLLLKQSNSRAHSPSPAKNQLIPRNLTPSSTQMQPMQRSHPHMGPMTGPHSTGMIPSSVSNTGPVKMVIKNGVLMPKQKQRRYRTERPFACEHCSARFTLRSNMERHIKQQHPQYWAQRQRSGHHIMRGRANSSSVLSHMQPNHSPLEAPHQINHSGIINHMSAIPDQVKYAILAKQLKARKETDILQQALSQGSNSVLTQTPNTAAITNLRKSLSSSSNTNNGSIEDDDPKLVIDEDDEKEDDHEDDDDDEEEEDCKAENLTQIQGYQEINEAAKKAAKSILEQAMKAGNTKSSFNPNGNDMETPVVKDFSLKLSKNMIAQAESVGKFLKEVASSPFKDESNDLASVSRLVDNATNAMSFNNYFRPSDVVNQAEQSDEEGLVASGSASESNNSGPEDMPGALEPKKKSAYSSAPNRVSCPYCQRMFPWSSSLRRHILTHTGQKPFKCSHCPLLFTTKSNCDRHLLRKHGNVESAVSLYVPIEDVNEPLPVPKSVEEIELQHQQQLQQQREQKKLEEQKELEEQKQVVQENNEQATPTTINAGCKVEPVPQIVSSSELPFKCHLCDSSFAERFQCLDHIKIHHAQEFALLLSKGAIDSEADVNSQVQSTEDDEKRDESRGKYPDYTNRKVICAFCVRRFWSTEDLRRHMRTHSGERPFQCDICLRKFTLKHSMLRHMKKHSGGSHSSNGAANAANSGSDISDDEQPPASVMLASTLRNHKIQELFSKANSEWRNNRLSGEHKENIEEHNNQSDLIGNLLGISDQGILNKLLSSADEAAKFLGVDK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01223735;
90% Identity: iTF_00314647;
80% Identity: -