Basic Information

Insect: Cheilosia vernalis
Gene Symbol: Zfx
Assembly: GCA_949126925.1
Location: OX421361.1:67725941-67727852[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 12 4.6 5.8e+02 2.1 2.0 1 23 179 204 179 204 0.84

2 12 0.0067 0.85 11.0 1.1 1 23 210 232 210 232 0.91

3 12 0.048 6.1 8.3 0.2 2 17 267 281 267 282 0.80

4 12 2.9e-05 0.0036 18.5 3.3 1 23 296 318 296 318 0.98

5 12 2.5e-06 0.00032 21.8 0.1 1 23 324 346 324 346 0.96

6 12 3.9e-08 4.9e-06 27.5 0.2 2 23 352 373 351 373 0.97

7 12 0.019 2.5 9.6 0.6 2 23 381 403 380 403 0.91

8 12 4.6e-06 0.00059 21.0 1.4 1 23 427 449 427 449 0.99

9 12 2.7e-05 0.0035 18.5 1.9 1 23 455 478 455 478 0.93

10 12 0.00016 0.021 16.1 0.4 1 23 484 507 484 507 0.93

11 12 0.00011 0.013 16.7 0.7 1 23 513 535 513 535 0.98

12 12 0.0051 0.64 11.4 0.6 1 17 541 557 541 558 0.90

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	12	4.6	5.8e+02	2.1	2.0	1	23	179	204	179	204	0.84
2	12	0.0067	0.85	11.0	1.1	1	23	210	232	210	232	0.91
3	12	0.048	6.1	8.3	0.2	2	17	267	281	267	282	0.80
4	12	2.9e-05	0.0036	18.5	3.3	1	23	296	318	296	318	0.98
5	12	2.5e-06	0.00032	21.8	0.1	1	23	324	346	324	346	0.96
6	12	3.9e-08	4.9e-06	27.5	0.2	2	23	352	373	351	373	0.97
7	12	0.019	2.5	9.6	0.6	2	23	381	403	380	403	0.91
8	12	4.6e-06	0.00059	21.0	1.4	1	23	427	449	427	449	0.99
9	12	2.7e-05	0.0035	18.5	1.9	1	23	455	478	455	478	0.93
10	12	0.00016	0.021	16.1	0.4	1	23	484	507	484	507	0.93
11	12	0.00011	0.013	16.7	0.7	1	23	513	535	513	535	0.98
12	12	0.0051	0.64	11.4	0.6	1	17	541	557	541	558	0.90

Sequence Information

Coding Sequence: ATGAGTGTGGCGGAAAATACTTGCAGGACATGTGGGAAAAAGTCGGAACAGGAGGATGGCTCGGATCTCTATCCAATGTACACCTCAACAGAATACCACAACGAATTAAGAATGGTTTTGGAGGAATTCGAAATATGGAATTTAAACATCGCACAAGGTGATGGCTTGCCTCAGAAGATTTGCCTTACTTGTTTCGACAGTTTCTGTCAAATACATAACTTCCGTATGATATGCCAAGAGGCACAGTCGAATTTTGGTGAACTATGTATTGGTCTGGATATTATAATAAAACTTGAAGCACAATAtggtgatgttgatgttgactaTCCAGAAGACTTCGAGGGCGAACAAACAATTACCGTTCAAGAGCACTACCAGTTCCCCGCTGATGAACCACAAAATGTTCCAGATGCAACCGCCGACTCAATAACATTTGAAAAACTCTTAGAAACTAATAACACTGTTGATGCTTTGGAAAAGAGCCAACAGAATGAGTTGGAGAAAGTGGTTGAGAATGTTTCCGACCGCAATCAGTATCAATGCGAATACTGCATGGATGTTGTCTGTTTCGATGATACAGAACTGCTTAATCAGCATTACAATGCCGTGCATTCGTCAGACCTTCCTTATCAGTGTCCTCAATGTGAAAAGTGCTTCGAGGTAAAGGCCAAACGCGATGGCCATGCTAGAGTCCACTTTCGAGAAACACTCGAATGTGAAACCTGTGGCAGGAAAATTCGTGGCGGTAAACGAATGATGGATCGCCACATTGAGGTGCATCACATCTTAAGGGTACGCGAATGTACTATATGTGGCAAGAGGTTTGACAAAATTACTCTGAAGAGATTTAACTACCACCTAAGCTGGCATAATGAAAACAAGTTGCACAAGTGCAAGTATTGCGATAAAAAGTTTATTCAAGTAAAACAATTAGTTGTGCATGAGAAGACGCACACCGGAGCGAATCCTTTTCTCTGCAATGAATGTGGAGTGGGATTTACAACTTCGGATCTTCTTGAGGCTCATATAAAAAGGCACGGAGTAGCGGATTTGCAATGCCCTATGTGTCCCAAATCATTCGCCCAACAACGAAACTTGAAGATCCACATGCAAATTCACGATCCGGATAAGAAAGGAATGCGCTGCGACATTTGCCCAAAGCTTTTTGGTTCTACTATGAATTTACGTCTGCATAACTACAAAAGACATGGTGCGCCCGCCACCCCTGCTATTCTGAATATCTTGGGAAAGCGCCAGAATTCAAAGCTGATAAAACCTTTCAAATGTAATATGTGTTCCCAATCGTTTGTCGTTCAAACACAATTGGAGAAGCATGTGAAAACTCACAGTGAAAACAGGCCGTACTCTTGCATTCAATGCGGCAAGTCATTTAAGCGAGATTCCCATTTGAAGTTGCACATGGATTCGGTGCACTTgaacaacaaacctcacaagtgCTCTATCTGTGGATGGGGCTTTCTACAAAAAAGCAGCCTGAGGGAGCATATTGCTGCTAAGCATGAACATAGCAAGGACTTCAAATGTGATGTTTGTGAAAAGACGTTTGCTATTGCAAAAACGCTTAAGATTCATAAGCTCAAACACTTGGAAAAGAAACCATTTAGCTGCACCGTATGTGACAAGAGCTTTAGACTACAAAATACTTTAAGAAGTAAATCAACCAGTTAG
Protein Sequence: MSVAENTCRTCGKKSEQEDGSDLYPMYTSTEYHNELRMVLEEFEIWNLNIAQGDGLPQKICLTCFDSFCQIHNFRMICQEAQSNFGELCIGLDIIIKLEAQYGDVDVDYPEDFEGEQTITVQEHYQFPADEPQNVPDATADSITFEKLLETNNTVDALEKSQQNELEKVVENVSDRNQYQCEYCMDVVCFDDTELLNQHYNAVHSSDLPYQCPQCEKCFEVKAKRDGHARVHFRETLECETCGRKIRGGKRMMDRHIEVHHILRVRECTICGKRFDKITLKRFNYHLSWHNENKLHKCKYCDKKFIQVKQLVVHEKTHTGANPFLCNECGVGFTTSDLLEAHIKRHGVADLQCPMCPKSFAQQRNLKIHMQIHDPDKKGMRCDICPKLFGSTMNLRLHNYKRHGAPATPAILNILGKRQNSKLIKPFKCNMCSQSFVVQTQLEKHVKTHSENRPYSCIQCGKSFKRDSHLKLHMDSVHLNNKPHKCSICGWGFLQKSSLREHIAAKHEHSKDFKCDVCEKTFAIAKTLKIHKLKHLEKKPFSCTVCDKSFRLQNTLRSKSTS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00314587;
90% Identity: iTF_00311256;
80% Identity: -