Basic Information

Insect: Cheilosia variabilis
Gene Symbol: RREB1_1
Assembly: GCA_951230905.1
Location: OX579677.1:41302877-41308665[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 0.031 4.3 8.8 0.8 1 21 236 256 236 258 0.93

2 14 0.00029 0.04 15.2 0.2 1 23 268 290 268 290 0.98

3 14 8.2e-06 0.0012 20.0 5.2 1 23 296 318 296 318 0.98

4 14 0.027 3.9 9.0 2.8 2 19 527 544 527 544 0.97

5 14 8.1 1.1e+03 1.2 0.8 1 11 590 600 590 610 0.83

6 14 0.0076 1.1 10.7 0.1 1 23 764 786 764 786 0.97

7 14 0.00015 0.022 16.0 1.7 1 23 795 817 795 817 0.99

8 14 0.0004 0.056 14.7 2.0 1 23 823 846 823 846 0.97

9 14 0.00082 0.11 13.8 2.1 1 23 1191 1214 1191 1214 0.95

10 14 7.4e-05 0.01 17.0 0.3 2 23 1521 1542 1520 1542 0.97

11 14 0.12 17 6.9 6.3 1 23 1548 1571 1548 1571 0.97

12 14 4.7 6.6e+02 1.9 5.3 1 23 1662 1684 1662 1685 0.93

13 14 0.0072 1 10.8 0.5 3 23 1734 1754 1732 1754 0.96

14 14 0.0012 0.17 13.2 4.8 1 23 1760 1782 1760 1782 0.99

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	0.031	4.3	8.8	0.8	1	21	236	256	236	258	0.93
2	14	0.00029	0.04	15.2	0.2	1	23	268	290	268	290	0.98
3	14	8.2e-06	0.0012	20.0	5.2	1	23	296	318	296	318	0.98
4	14	0.027	3.9	9.0	2.8	2	19	527	544	527	544	0.97
5	14	8.1	1.1e+03	1.2	0.8	1	11	590	600	590	610	0.83
6	14	0.0076	1.1	10.7	0.1	1	23	764	786	764	786	0.97
7	14	0.00015	0.022	16.0	1.7	1	23	795	817	795	817	0.99
8	14	0.0004	0.056	14.7	2.0	1	23	823	846	823	846	0.97
9	14	0.00082	0.11	13.8	2.1	1	23	1191	1214	1191	1214	0.95
10	14	7.4e-05	0.01	17.0	0.3	2	23	1521	1542	1520	1542	0.97
11	14	0.12	17	6.9	6.3	1	23	1548	1571	1548	1571	0.97
12	14	4.7	6.6e+02	1.9	5.3	1	23	1662	1684	1662	1685	0.93
13	14	0.0072	1	10.8	0.5	3	23	1734	1754	1732	1754	0.96
14	14	0.0012	0.17	13.2	4.8	1	23	1760	1782	1760	1782	0.99

Sequence Information

Coding Sequence: ATGTTGAAAACACCAATTAAAAAGCAATTAACAGACATTCCACTGCGCAAAATGGATCGACGCGACTCAACAACATCGGACTCATCTGTCGAACCCATGGACTTGGGACGTACACcagaaatgaaaaaacaaaccaaCACAACAGCATTACAGATGCCAACAGCAGTAACACTTAAAGATGCCATTTTATCAGATGCCAATACAAAATACCCCATACGTCATGAATCTGATGCCGACGAATCAGAAGACAAAGACAGAGATCACCATCAGCGGCGATCCCACAGTCAACATCACTACCATCATCGTCGGCGCGGTGGTAACAGTGGACGCGATAAACGTACCGTCCACTTGGAATGCACCGACACTCCACATTCGTTGCGAAAGAAATTTCGCTTCAGCAGCACGCAAAACCCATCGGTTCCAGAGACTGTGATCAATTTgaaacaacagaaaacatcgaacaATGATTCCACGTTATCGGGGAAGTCAGCAAATCTAACCGCTGCAACGAACAACAATGAATCTGGCTTTGTGGACGCCAGCAGCAGTCATGTTCTAAACACATCCGCTTCATCGGCGACATCATCcacatcgtcatcatcgtcgtcgccgACATCATCATCGTCGGCGGCGGCGTCACCATCCGCCAGTAATATCGCCGTTTCGAGTCCCGAATCGGGCGTTGGCGAACGTGACGACATGAAGTACCTTTGCCCAATTTGTGAGGTGGTATCGGCGACACCGCATGAATTTACCAATCACATCAGATGTCATAATTATTCATCTGGGGACACCGAAAATTTCACCTGCCGCATTTGCTCTAAGGTTCTATCATCTGCCTCATCGCTGGATCGACACGTTCTGGTGCACACTGGTGAACGGCCCTTCAATTGCAAATATTGCCAACTGACATTCACCACAAATGGCAACATGCATCGTCACATGCGAACCCACAAACAGCACCAGCAACACTATCATCGCAACTCAAATGGTACAAAGGGGGGTggaagtggtggtggtggtggtgcgacGATTGCGGGTGCTAATGGTGGCAGCTCCGGCTTAATACCAAATATGCCATCAAACGACCAATCGGCTGCTGTGCCCTCTAAACCAACTATCGTTACCAATGGTGTCGTTATTAACAGCAACGGTGACACAATTAgaggaggtggtggtggtggtggtggtggcgaaAGTTACGAAAGTGATGGTGGTTGCTCAACGGATTCATCAAGTGCCATCAGCCAAAGttccaataacaataacaacagcAATACGAACAACAAAAACATTAGCAATTTTAAGCGCAAGAGCACCGACAGTTTGGATGACATGGCCATGATGAAGCGACGCGTGAAGACcaccatcaacaacaacaatatcatCGATAACAACATGCACACCGCCATTCAAAAGAGTACGATCGAAGAGGCTGACGACGACTTgaagcagcagcaccagcagcaacaacaactacaacagaAGCTCTTTTGTCCGGTATGCAATCGCAGTGACTTTGTGGGTATGCTCGCATTGGGCTCCCATATGGACTGCGATCATTCGGATATTCCTGCCAAGTGCCGTCATTGTGATGTTGTTTTCAAGACACACAAGCAACTGAACGTACATCCATGCACAAGTAAGCTTAAGATCACACACGGCTTTAAGGATCTTACGTTTGTGGACTTTTCGAGCGAAAAGTTCCCCCTCATTGCCAAGTCTTTATGTGAGCAGAGCCTGAGGACGTCAGTGGGTAGTCAAAAGTTTGAGTGCTCCAAGTGCTATCGAGCATTTCCGTGCGCCACTGCTGTGGAAATACATGAAAAAGAGTGCGCCACATCAGGGATGAATTTGTTCGTCGATGCACATGACTTCTCCATTCGCAAGCAGCGATCGTATAGCGAGAGTTCAGGTGGCGCTGACGATGACGACAATCGGCGGGAGGAGTTCTTCGCCCGTTTGTACTTAAAGAACAAATCTACAGTACAAAGTATGACCAGCTTATCGTTATCGTCCCCTTCGCTGTCTGATGTTAAGTCGTCCGAGTTGGACAAGACACCTGTAAAAATGTCCCAGTCCCAGCTCGACCAATACCACGACACCAAAGAGCTAGCCGACATTCAATCCATTCTCAACATAACTTCATCGTCGTCAACAAGTAATTTCCTTCGCAACTTTGAAAACTCTGTGAACACACCGATCAGTAATTACGGAACCGAAAATGGCGAAGAGGAAGCCCAAGATGCATTCACTTCCGAGTTTCGCAAGATGAAGTTGCGCGGGGAGTTCCCTTGTAAGTTGTGCACGGCAGTGTTTCCCAACCTTCGCGCTCTAAAGGGCCACAATCGCATACATCTCAGCGCAGCTGGGCCCGGTCCATATCGCTGCAATATGTGCACATATTCAATCCACGATAAGGCGGCACTGGTGCGTCATATGCGAACACACAACGGCGACAGGCCGTACGAGTGCGCCATCTGTAACTATGCATTCACTACAAAAGCCAACTGCGAACGGCATTTGCGCAATCGACACGCCAAAACCACACGCGACGATGTAAAGCGCGCGATTATATACCATCCATCGGAGGACTCGAACTGCGATGACGCCATGAAGAAGCTGCACATGTTCTCCTCGCCGGAATTTGATCAAGACGACATGGAGCAACACCATCCACCAAAGGACCGATCCACTCCGGTATCACATCTAAAGGAAATGCTCCAGTCCGAGTCGAAGCCGCTCAAGATTCAAGTGAAGAGCTTGGAGAAGTTAATAGACAAAGCGGCACCATCATTTAATCAATCAGATGACATTGAAAAAGAACTGGAACGAAATGATGTCCAACACGATAAGGCCAGTCGACCGATTGATCTTAGCATGGATGCATTGGATTTAAGCAAAAAGCCCGTGAAGGCACCTACAAATCCAGAAAAACCACCACAATCTCCCATACCGCCTCAGATAACACCTGGACGTGCACAACCCGAAGAGCAAAATATCGATATGCATCTTTTGGAAAACAACCAACAGTTGCTGCTGGCCCAGCAGCGATTGTTGAACGCAGCCATGCCGAAAATGGATCCCGCACACTATTTGCAGCTCTCGCAGCTTTATCGCAACTTGGTGCTGCAGCCATTTAACCCGTTTTTCCTACAAAACTCATTCCTATCGAACAACATCAGTGATCTAAATAAATTCGCTCCGCTGATGAATCCACTTTTCGATCATCCCGTAGCCTCAGAGACGTTCGCCGCCGGCAACTATAACCAAAGTATGCAGCCAAAGATAGTACCAGaagaagccaacttattgttgAAGCAGTCCAATTCCCGGGCTCACTCCCCGACTCCGGCTAAGAACCAATTAATACCGCGGAACCTCACTCCATCGTCGACACAGATGCCGCCCATGCCACGAAGCCATCCGCATATGGGGCCCATGACGGGACCACACTCCACAGGAATGATCCCATCATCGGTGTCCAACACAGGCCCAGTGAAGATGGTCATTAAGAACGGTGTGCTCATGCCCAAGCAAAAGCAGCGTCGTTATCGCACCGAACGCCCCTTTGCTTGTGAACATTGCTCCGCTCGCTTCACCTTGCGTTCGAATATGGAGCGCCACATCAAGCAACAGCATCCCCAGTATTGGGCTCAACGGCAACGTAGCGGTCACCACATCATGCGAGGTCGTGCCAACAGTAGTTCGGTCCTCTCGCACATGCAGCCGACTCACTCGCCCTTGGAAGCTCCACATCAGATTAACAGCAGTGGAATAATAAATCACATGAGCGCTATCCCCGATCAGGTAAAATATGCCATTCTCGCCAAACAGCTCAAGGCCCGCAAGGAGACAGACATTCTACAGCAAGCCCTGTCCCAGGGCTCTAGCAGTGTGTTAGCACAGAACCCCACCACCGCCGCCATCAGTAATCTTCGAAAATCACTCAGCTCCTCGTCGAACACAAATAATGGTAGCATAGAGGACGACGATCCCAAGCTCGTTATCGACGAGGACGACGAAAAGGAAGACGATcacgaagatgatgatgatgatgaagaagaGGAAGATTGTAAGGCAGAAAATTTGACGCAAATTCAAGGCTACCAAGAAATCAATGAAGCTGCAAAAAAAGCTGCCAAGTCCATTTTGGAGCAGGCCATGAAAGCTGGCAGCGCCAAAAGCTCATTTAACCCGAATGGGAACGATGTGGAAACTCCAGTTGTAAAGGACTTCAGCCTCAAACTGTCCAAAAATATGATTGCTCAAGCAGAGTCCGTCGGCAAATTCCTCAAGGAAGTAGCCAGTTCTCCGTTCAAGGACGAATCCAATGATCTCGCTTCGGTGTCAAGACTCGTTGACAACGCCACCAATGCGATGTCTTTCAACAATTACTTTCGACCCAGTGATGTTGTCAACCAAGCGGAACAAAGTGACGAAGAGGGTTTGGTTGCATCGGGCAGCGCATCCGAAAGCAATAACTCTGGCCCCGAGGATATGCCCGGCGCGCTGGAACCAAAGAAGAAATCTGCCTACAGCTCGGCGCCAAACCGAGTATCATGTCCCTATTGCCAGCGAATGTTTCCCTGGTCTAGTTCACTGCGGCGACACATTCTAACCCACACCGGTCAGAAGCCCTTTAAATGTTCCCATTGCCCgctgcttttcaccaccaaaagcAATTGCGATCGTCACCTACTTCGAAAGCACGGTAATGTCGAATCGGCTGTGTCGCTGTATGTCCCAATCGAGGATGTAAATGAGCCGTTGCCAGTTCCCAAGTCAGTCGAGGAGATTGAGctgcaacaccaacaacagctTCAGCAgcagagagaacaaaaaaaacttgaagATCAAAAAGAGCTGgaagaacaaaaacaagtggTTCAGGAGAATCATGAACAGGCAACCCCAACGACCATAAACACGGGTTGCAAAGTAGAACCAGTACCGCAAATTATCTCATCGTCCGAGCTGCCGTTCAAGTGTCACCTGTGTGACAGTTCGTTTGCCGAACGATTGCAGTGTCTCGATCATATCAAGATCCATCATGCTCAGGAGTTCGCGCTACTGCTTTCCAAGGGCGCCATAGACAGCGAAGCCGATGTCAACAGCCAAGTACAGTCAACCGAGGACGACGAAAAACGAGATGAAAGCCGCGGCAAGTATCCCGACTATACCAACCGCAAGGTTATCTGCGCCTTCTGCGTTCGTCGTTTCTGGTCCACGGAAGATCTGCGTCGTCATATGCGGACTCACTCGGGCGAAAGGCCATTTCAGTGCGACATCTGCCTGCGCAAGTTCACTCTGAAGCACAGCATGCTGCGTCACATGAAGAAACACAGCGGCGGCAGTCATTCTAGTAACGGTGCCGCGAACGCCACCAACAGTGGTTCCGACATATCCGACGATGAACAGCCCCCAGCCAGTGTTATGCTGGCAACCACTCTTCGCAACCACAAAATCCAGGAGCTCTTTTCGAAGGCCAACAGCGAGTGGCGCAACAATCGACTCTCGGGCGAGCACAAGGAAAACATCGAAGAGCACAACAATCAGTCCGATCTAATTGGCAACCTGCTTGGCATCAGCGACCAGGGCATCCTCAACAAGCTTCTCTCGTCGGCGGATGAGGCGGCCAAGTTTTTAGGTGTCGACAAGTAA
Protein Sequence: MLKTPIKKQLTDIPLRKMDRRDSTTSDSSVEPMDLGRTPEMKKQTNTTALQMPTAVTLKDAILSDANTKYPIRHESDADESEDKDRDHHQRRSHSQHHYHHRRRGGNSGRDKRTVHLECTDTPHSLRKKFRFSSTQNPSVPETVINLKQQKTSNNDSTLSGKSANLTAATNNNESGFVDASSSHVLNTSASSATSSTSSSSSSPTSSSSAAASPSASNIAVSSPESGVGERDDMKYLCPICEVVSATPHEFTNHIRCHNYSSGDTENFTCRICSKVLSSASSLDRHVLVHTGERPFNCKYCQLTFTTNGNMHRHMRTHKQHQQHYHRNSNGTKGGGSGGGGGATIAGANGGSSGLIPNMPSNDQSAAVPSKPTIVTNGVVINSNGDTIRGGGGGGGGGESYESDGGCSTDSSSAISQSSNNNNNSNTNNKNISNFKRKSTDSLDDMAMMKRRVKTTINNNNIIDNNMHTAIQKSTIEEADDDLKQQHQQQQQLQQKLFCPVCNRSDFVGMLALGSHMDCDHSDIPAKCRHCDVVFKTHKQLNVHPCTSKLKITHGFKDLTFVDFSSEKFPLIAKSLCEQSLRTSVGSQKFECSKCYRAFPCATAVEIHEKECATSGMNLFVDAHDFSIRKQRSYSESSGGADDDDNRREEFFARLYLKNKSTVQSMTSLSLSSPSLSDVKSSELDKTPVKMSQSQLDQYHDTKELADIQSILNITSSSSTSNFLRNFENSVNTPISNYGTENGEEEAQDAFTSEFRKMKLRGEFPCKLCTAVFPNLRALKGHNRIHLSAAGPGPYRCNMCTYSIHDKAALVRHMRTHNGDRPYECAICNYAFTTKANCERHLRNRHAKTTRDDVKRAIIYHPSEDSNCDDAMKKLHMFSSPEFDQDDMEQHHPPKDRSTPVSHLKEMLQSESKPLKIQVKSLEKLIDKAAPSFNQSDDIEKELERNDVQHDKASRPIDLSMDALDLSKKPVKAPTNPEKPPQSPIPPQITPGRAQPEEQNIDMHLLENNQQLLLAQQRLLNAAMPKMDPAHYLQLSQLYRNLVLQPFNPFFLQNSFLSNNISDLNKFAPLMNPLFDHPVASETFAAGNYNQSMQPKIVPEEANLLLKQSNSRAHSPTPAKNQLIPRNLTPSSTQMPPMPRSHPHMGPMTGPHSTGMIPSSVSNTGPVKMVIKNGVLMPKQKQRRYRTERPFACEHCSARFTLRSNMERHIKQQHPQYWAQRQRSGHHIMRGRANSSSVLSHMQPTHSPLEAPHQINSSGIINHMSAIPDQVKYAILAKQLKARKETDILQQALSQGSSSVLAQNPTTAAISNLRKSLSSSSNTNNGSIEDDDPKLVIDEDDEKEDDHEDDDDDEEEEDCKAENLTQIQGYQEINEAAKKAAKSILEQAMKAGSAKSSFNPNGNDVETPVVKDFSLKLSKNMIAQAESVGKFLKEVASSPFKDESNDLASVSRLVDNATNAMSFNNYFRPSDVVNQAEQSDEEGLVASGSASESNNSGPEDMPGALEPKKKSAYSSAPNRVSCPYCQRMFPWSSSLRRHILTHTGQKPFKCSHCPLLFTTKSNCDRHLLRKHGNVESAVSLYVPIEDVNEPLPVPKSVEEIELQHQQQLQQQREQKKLEDQKELEEQKQVVQENHEQATPTTINTGCKVEPVPQIISSSELPFKCHLCDSSFAERLQCLDHIKIHHAQEFALLLSKGAIDSEADVNSQVQSTEDDEKRDESRGKYPDYTNRKVICAFCVRRFWSTEDLRRHMRTHSGERPFQCDICLRKFTLKHSMLRHMKKHSGGSHSSNGAANATNSGSDISDDEQPPASVMLATTLRNHKIQELFSKANSEWRNNRLSGEHKENIEEHNNQSDLIGNLLGISDQGILNKLLSSADEAAKFLGVDK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01223735;
90% Identity: iTF_00314647;
80% Identity: -