Basic Information

Insect: Cheilosia variabilis
Gene Symbol: -
Assembly: GCA_951230905.1
Location: OX579679.1:54192568-54195252[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 13 0.95 1.3e+02 4.1 0.3 1 12 16 27 16 29 0.91

2 13 0.00061 0.086 14.2 0.2 1 23 320 343 320 343 0.94

3 13 0.29 41 5.7 4.5 1 23 352 374 352 374 0.98

4 13 0.00012 0.017 16.4 4.2 1 23 381 403 381 403 0.98

5 13 7.1e-05 0.01 17.1 0.4 1 23 409 431 409 431 0.99

6 13 8.5e-05 0.012 16.9 1.1 1 23 438 460 438 460 0.97

7 13 4.2e-06 0.00059 21.0 0.4 1 23 466 488 466 488 0.97

8 13 6.8e-05 0.0096 17.2 0.3 1 23 494 516 494 516 0.98

9 13 7.3e-06 0.001 20.2 0.3 1 23 522 545 522 545 0.95

10 13 0.0002 0.029 15.7 3.7 1 23 551 574 551 574 0.97

11 13 1.4e-05 0.0019 19.3 3.5 1 23 580 602 580 602 0.98

12 13 0.00031 0.044 15.1 0.4 1 23 608 630 608 630 0.96

13 13 0.00065 0.092 14.1 1.0 1 22 636 657 636 660 0.92

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	13	0.95	1.3e+02	4.1	0.3	1	12	16	27	16	29	0.91
2	13	0.00061	0.086	14.2	0.2	1	23	320	343	320	343	0.94
3	13	0.29	41	5.7	4.5	1	23	352	374	352	374	0.98
4	13	0.00012	0.017	16.4	4.2	1	23	381	403	381	403	0.98
5	13	7.1e-05	0.01	17.1	0.4	1	23	409	431	409	431	0.99
6	13	8.5e-05	0.012	16.9	1.1	1	23	438	460	438	460	0.97
7	13	4.2e-06	0.00059	21.0	0.4	1	23	466	488	466	488	0.97
8	13	6.8e-05	0.0096	17.2	0.3	1	23	494	516	494	516	0.98
9	13	7.3e-06	0.001	20.2	0.3	1	23	522	545	522	545	0.95
10	13	0.0002	0.029	15.7	3.7	1	23	551	574	551	574	0.97
11	13	1.4e-05	0.0019	19.3	3.5	1	23	580	602	580	602	0.98
12	13	0.00031	0.044	15.1	0.4	1	23	608	630	608	630	0.96
13	13	0.00065	0.092	14.1	1.0	1	22	636	657	636	660	0.92

Sequence Information

Coding Sequence: ATGACGGAAATCATCAACCAAATTTCAAACTACACGACAGAACTTTTCAAGTGCTTCCTTTGCGATCGAATATTCGCAGATGGCGACGAACCATGGCATTTGTTCGAGAAGAGGCTGCTTGAAAACGGTCAGCAAGACTGTCCGCTGGCTACAATTTTATCATCTGCATTGGGGAAGGAAATCGAACAGGAAAATGTCCACTCCAAGTTGCTCTGCGACGAGTGCAATTTAATACTTGTAGAGTATGAGAGTGTAGAGAAGAGATTCTATCAGTTTCGTTTGAAAATTCTGTCCGACTATAATAACACGGCAAAAGAGAATGGACTCGATCCGGTTTGGTTCGAGATAGGCGATGTGGAGGATAGCACTCAAACTGATTCGCAACTAGTCGAAGGCGAGAGCACTTTGAATGTGGAAGAAGTCAAAATCGAACGCGATATGGACGAGAGTGTTGCCATTCCCATGTTGGTCCATCAAGAAATCGATAGTTTTGTGGTGGAGGAAGTTCAGGGGCAGTTCCAAGACGGTATAGTTCCAGAGTTTGTCACAGAAGGAGTAGCTGTGATTAATGAGGACGTTCAGGAATTGGAGGATGCTGCTAGTACCGCATATGCGGAGCGAAATATACAAGTTATGGGAGAAGAAATAACCTACGAGCAGATAATAGAACAGAACTCCGTCATCAGCTACGACAACAGTGTGGATGCCGCCGAGTCCGTAATAGGGTACAACAGCAGCAATGACGTTTCAGATGAATCTCCAATACTCCCCGACGACATTCCGAAGCCGCAGAAGCAAAAACGCACATCACGTACAGTCAAACGGGAACCCGAAACAGAGCCGATTGACTTTGAACTGGCCGACAACATGTACGTCTGTATACTGTGTCCAGATAAAAGCGAACACGAGCCGATTGTGTTCCCGAATCACTTGAAAAACGTTCACAACTACAAGTTCTACGTGTGCGACATGTGTAACAAGGGGTTTAACAAACGAAACGAAATCAATGACCACATGGATGAGGCGCACGGTGGCGGAGCCGAGGAAGGCGAGTTTCAGTGTGAAACGTGTCTTCGGGTGTTTCTGAATCATCGCCTCTTTCGTAACCACAAACGACTGCACTATATTTCGACAAAGCATCATGAATGCTCCGAGTGCCATAAGAAGTACAGCTCGAAAAATCTGCTCGATGAGCACATGAATATGCACACCGGGAAGCGCCCCTACAAGTGTGCGTCGTGTGCCAAGGACTTTGCCTCGAAATATACCCTGCAAGCGCACTTGAAGATCCATACGAAGCGACCCAGACCGTATAGTTGCGATGAGTGTGACAAATCGTTCCTGAATCAACAGAACCTGGTGCAACACAAAAAGCTGCACTCGGGACTCAAGTCGTATGTCTGTGAAATTTGTCAGAAGGCGTTTGGTACTCAGCACAACCTGGAAGTGCATAAAATTGTTCACTCGGGCAACAAACCGTTCATTTGCCGGACGTGTGGGAAAGGCTTTGCACGTCGGGCTGAGATTCGAGATCACGAGCGTACGCACACCGGCGAGAGGCCGTTCAGGTGTGACATTTGCCCGATGGCGTTCGCCCAGAGGTCGAACCTAATGACGCACAAGAAAGCCACTCATCTGAACGACAAGAAGCACAAGTGCACGCTGTGCGAAAGGTCATTCAAGCGGCGGAGACTGCTGGAGTATCATACTCAGTCGGCGCACACCGGCGAACGACCCCACAAGTGCGAGGTGTGCAGCGCCACCTTCGTCTATCCGGAGCACTTCAAGAAGCACATGCGCATCCATAGCGGAGTTAAACCGTACGCATGCGAGGTCTGCGGCAAGCTGTTCAATAGCAGGGACAACCGAAACGCACACAGGTTCATCCACAGCGAGAAGAAGCCCTACGAGTGTTTGAAATGCGGAATGGGCTTCATGCGGAAGCCGCTGCTGCTGGCCCACATGAAACACACCAAGCATGTCAACGACACCATTATTGTGAATCAACCGCAAATCAGTCACAAAGGTGTTGAAGAAGTCGAAAACGAGCTGACAGACGAAGACCTGGAGTTGAATAGTCGACGTGTATCCATTGTAGACAGAGCATCATCGTTCGATGAGGCGGCTACCGCCGACACGATACTAGTTGAAGATGGCGACGGACAGTACATCAAGGACGAGGATGGCGAAGTGAAATACCTGCAGTTCACCGAGATGGACAAGGATGGACAGGCGACGTATTGGGTGGACATCGGCGACGACAAGGAAGACGATAATTAG
Protein Sequence: MTEIINQISNYTTELFKCFLCDRIFADGDEPWHLFEKRLLENGQQDCPLATILSSALGKEIEQENVHSKLLCDECNLILVEYESVEKRFYQFRLKILSDYNNTAKENGLDPVWFEIGDVEDSTQTDSQLVEGESTLNVEEVKIERDMDESVAIPMLVHQEIDSFVVEEVQGQFQDGIVPEFVTEGVAVINEDVQELEDAASTAYAERNIQVMGEEITYEQIIEQNSVISYDNSVDAAESVIGYNSSNDVSDESPILPDDIPKPQKQKRTSRTVKREPETEPIDFELADNMYVCILCPDKSEHEPIVFPNHLKNVHNYKFYVCDMCNKGFNKRNEINDHMDEAHGGGAEEGEFQCETCLRVFLNHRLFRNHKRLHYISTKHHECSECHKKYSSKNLLDEHMNMHTGKRPYKCASCAKDFASKYTLQAHLKIHTKRPRPYSCDECDKSFLNQQNLVQHKKLHSGLKSYVCEICQKAFGTQHNLEVHKIVHSGNKPFICRTCGKGFARRAEIRDHERTHTGERPFRCDICPMAFAQRSNLMTHKKATHLNDKKHKCTLCERSFKRRRLLEYHTQSAHTGERPHKCEVCSATFVYPEHFKKHMRIHSGVKPYACEVCGKLFNSRDNRNAHRFIHSEKKPYECLKCGMGFMRKPLLLAHMKHTKHVNDTIIVNQPQISHKGVEEVENELTDEDLELNSRRVSIVDRASSFDEAATADTILVEDGDGQYIKDEDGEVKYLQFTEMDKDGQATYWVDIGDDKEDDN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00724974;
90% Identity: iTF_00316203;
80% Identity: -