Basic Information

Insect: Cheilosia variabilis
Gene Symbol: ZFX
Assembly: GCA_951230905.1
Location: OX579679.1:51796204-51799256[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 20 0.002 0.28 12.5 0.5 1 23 104 127 104 127 0.96

2 20 0.00061 0.086 14.2 1.8 1 23 133 155 133 155 0.98

3 20 0.00011 0.015 16.5 1.3 2 23 165 186 164 186 0.97

4 20 5.9e-05 0.0083 17.3 0.9 1 23 192 215 192 215 0.97

5 20 0.022 3 9.3 1.3 1 19 247 265 247 267 0.96

6 20 6.2e-07 8.7e-05 23.6 0.3 1 23 275 297 275 297 0.98

7 20 1.4e-06 0.0002 22.4 0.8 1 23 303 326 303 326 0.98

8 20 0.13 18 6.8 2.1 1 23 336 359 336 359 0.91

9 20 9.6e-07 0.00014 23.0 2.0 3 23 452 472 450 472 0.97

10 20 1.1e-06 0.00016 22.8 0.5 1 23 478 500 478 500 0.99

11 20 0.00018 0.025 15.8 0.5 1 23 511 535 511 535 0.98

12 20 0.0037 0.53 11.7 2.2 1 20 541 560 541 562 0.94

13 20 0.064 9 7.8 2.7 1 23 600 622 600 622 0.97

14 20 3.6e-05 0.0051 18.0 4.8 1 23 628 650 628 650 0.98

15 20 4.2e-05 0.0059 17.8 1.2 1 23 656 678 656 678 0.96

16 20 0.00028 0.039 15.2 2.3 1 23 684 706 684 706 0.97

17 20 1.7e-07 2.4e-05 25.3 2.9 1 23 804 826 804 826 0.98

18 20 0.00033 0.047 15.0 0.4 1 23 832 854 832 854 0.98

19 20 0.00018 0.026 15.8 0.3 3 23 863 883 861 883 0.98

20 20 0.00012 0.017 16.4 4.8 1 23 889 911 889 912 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	20	0.002	0.28	12.5	0.5	1	23	104	127	104	127	0.96
2	20	0.00061	0.086	14.2	1.8	1	23	133	155	133	155	0.98
3	20	0.00011	0.015	16.5	1.3	2	23	165	186	164	186	0.97
4	20	5.9e-05	0.0083	17.3	0.9	1	23	192	215	192	215	0.97
5	20	0.022	3	9.3	1.3	1	19	247	265	247	267	0.96
6	20	6.2e-07	8.7e-05	23.6	0.3	1	23	275	297	275	297	0.98
7	20	1.4e-06	0.0002	22.4	0.8	1	23	303	326	303	326	0.98
8	20	0.13	18	6.8	2.1	1	23	336	359	336	359	0.91
9	20	9.6e-07	0.00014	23.0	2.0	3	23	452	472	450	472	0.97
10	20	1.1e-06	0.00016	22.8	0.5	1	23	478	500	478	500	0.99
11	20	0.00018	0.025	15.8	0.5	1	23	511	535	511	535	0.98
12	20	0.0037	0.53	11.7	2.2	1	20	541	560	541	562	0.94
13	20	0.064	9	7.8	2.7	1	23	600	622	600	622	0.97
14	20	3.6e-05	0.0051	18.0	4.8	1	23	628	650	628	650	0.98
15	20	4.2e-05	0.0059	17.8	1.2	1	23	656	678	656	678	0.96
16	20	0.00028	0.039	15.2	2.3	1	23	684	706	684	706	0.97
17	20	1.7e-07	2.4e-05	25.3	2.9	1	23	804	826	804	826	0.98
18	20	0.00033	0.047	15.0	0.4	1	23	832	854	832	854	0.98
19	20	0.00018	0.026	15.8	0.3	3	23	863	883	861	883	0.98
20	20	0.00012	0.017	16.4	4.8	1	23	889	911	889	912	0.96

Sequence Information

Coding Sequence: atgcaaaataataccGACCTATTTACTCCACTTCCAGTGGATATATCCACTCCAAATGCTCTGCTTTACCAGCTCAACGATTCGGACGAGAAATTCCTTAGGTCCACCGAATTCTATGCCTTCGAAATGGATAGTTTTACTGTGCCCGAAATCGATACAATATCCGGCCTAAGTCCGATTCCGGAAGAAACAGCTTGCTCATTGCACGTACCTCCGATAGACACGCTGTTCTCTTCGGTCGATCCAGCACATTCACAGCAAAGATTTCAATGCACGGACTTGCCTGTGCCTTCAGCTCTATCGAAACAATTTGCATGTGACCTGTGTTCGGAGACGTTTTCTTCGACACAAGTATTGCGCCTGCACCGACGAGTTCAACATATTTTGACCAAGGAATTCCGTTGTCGCAAGTGTCCGGCATCATTTAATTTTGAATCGAATTTGCACCTCCATCTGGCTTCGCATGTTCCCAGCAGTTGCAGCACGAACAAGGAGTGTCCCGAGTGCAAGATGTCGTTCAAGCGAATTTCCAGCTTTAAAGGCCACCTGAAGTCACATCAGACTAACGACCTCTTTAAATGCAATCGGTGTGAAAAAGAATTCGAATCGAAGGGCTACTACGAGAAGCACTTGGCAACGGCACACAAGCCCGGCGTCGATGGGACCGTTGAGGAGATTCTCGCTACAGTCTCCAGCAATGCCAGAAGTCGCATCAGGTCCAAGAAAGTGCAAGGCAAATACCAATGTCAGACATGTGGAAAGGACTTTCTAAAGCCCTGTCTGCTAAAGCGTCACGAGGTCTGTCATACGGGTGCGAAGCCATTTCAGTGCACCGAGTGCGATCAAGCGTTCACACAGAAACCATCTTTAGCAAGACACATGCTGTTGCATCAGGGCGTCAAGGACTTTAAATGTCCGAAGTGCAGCTTGAGCTTTGCACAGAAGAATAATCTTATAGTGCATATCAAGCGCACTCACCCAATGCGTCCCAATATGGATAACATGTTTGCGTGCGACTTCTGCTCATGTGTGTTCACGAAACTCAACAGCGTCAATCGGCATAAGGCGCTTATGCACCCGATGGGGGACACCGGTGCCGAAAACGATGGATttaacgatgacgacgacgacaatgTGAATGTCGCAAAGGTAATGGAGCAACTGAAGAGCTTCCAAGAGTCCATGAACATTATGGATATGCAACCTCCAGCGCTGGAGCTTTCGCTGCTGAAACCACCATCGCCAGGACCAAAGATACGAACAGTGACTGTGGTCGATACATTAAATCCGAAGAAGGAGAAGACCTTCAAGATGGTGAAAGAAATTTCCTACAAGGGACAACGCACGCTGGCCTGCGTGCACTGTGATAAGGCCTTCAAGAGACAATTCGATTTGCTTAGACACCTTCGTACCCACACCCAGGAGAGGGCATTCCAGTGTGAATTTTGCGAAAAAGCCTTTACTACAAGTGCTGCTCTCAAAATTCATTACAGAGTTCACATTTCATTAAACGAAAAGCCAGCAAAAGTGTACTCCTGTACAGTAGCAGATTGTGGAAAGCGATTCCCATCGATGCGAAAGCTGGACATGCACACAAGGACTCACTTGAGCTCCGTGTCGTACATTTGTTCGCTGTGCTCAAAAAGCTTCTCGTCCAAAGCCGGCTTCTCGGCCCACAAGCACCATCCACAGGATAGAGAGTTTGACATGGTTCGTCCATTCCTAGAGCCACCAGTGAAGCTAGACTCAAACGACACTGAAGAGGCGGACAAAATTGACGAATACTCGAAAAGAAGTCACCAATGCAGTGTCTGCGGCCTAAAAATGCAGAAGTTATCTCACTTGCAACAGCACGAAGCCACACACACGGGCGAGAAACCGTTCAAGTGTTCCATATGCTTCAGGTCTTATACAACGAAAAGTTCCCTCAATCTGCACCACAAAATCCACACCGCTGAAAAGCCTCACGCGTGTAAAATCTGTGACTCAAAATTTATAACACAATCAGTCCTCCAGCGACACATGATTTCGCACAGCAACGAGCGCAAGTTCGCCTGTCCATACTGCAGCGAACGCTTCAAGAGCAACGACAATTGCAAGAATCACATTTTGATGCATGCCCGCAGTCTCTTGGCGTCTCCTGAAATCAGCCCACTTCAAGAGGCATATCCCGAGCCGTCCTCGCCCGCACCAGAAGCTTCTTCTCCAGAGACTGTCGCTAAACCCTTCATTGCAGTTGTTCAAAGCCCCCAGAAGAATGCATCGCCAAAGTTCATACAGCTGGAGATGGTCAAGGACTGCAAAAAGCACACTCATAAAAACCTCACCATCGAAACTGTGACCAGTTCGCCGAAGAAGTCGTCGAAGAAATCACTGGCACGATCATTGAAACAGATTAGCCAAATTGGCCATCGGTGTGGCGAGTGTGGTAAAACGTTCTACAAAGCCAGCGATCTGCAACGGCACACGAGGACGCATACCAAGGAGAAGCCATTCGAATGCAGTCTCTGCTCGAAAGGATTTGCCTTGATGTCTACTTTGGGACAGCATATGAAAACGCACGACACGCTGAGAGAGACATTTGGCTGTCAAGTGTGCGGCAAGAAGTACAGCTCCCGAAAGGTGCTGCTGGTGCATCTGAGAATCCACACCGGTGAGCGGCCATTTCAGTGCGGTGTATGCAAAAAGACCTTTCGAACTTCGGGTCATAAGATTTCGCATATGAAGGCGCATCACAAGAAGAGGAAATGA
Protein Sequence: MQNNTDLFTPLPVDISTPNALLYQLNDSDEKFLRSTEFYAFEMDSFTVPEIDTISGLSPIPEETACSLHVPPIDTLFSSVDPAHSQQRFQCTDLPVPSALSKQFACDLCSETFSSTQVLRLHRRVQHILTKEFRCRKCPASFNFESNLHLHLASHVPSSCSTNKECPECKMSFKRISSFKGHLKSHQTNDLFKCNRCEKEFESKGYYEKHLATAHKPGVDGTVEEILATVSSNARSRIRSKKVQGKYQCQTCGKDFLKPCLLKRHEVCHTGAKPFQCTECDQAFTQKPSLARHMLLHQGVKDFKCPKCSLSFAQKNNLIVHIKRTHPMRPNMDNMFACDFCSCVFTKLNSVNRHKALMHPMGDTGAENDGFNDDDDDNVNVAKVMEQLKSFQESMNIMDMQPPALELSLLKPPSPGPKIRTVTVVDTLNPKKEKTFKMVKEISYKGQRTLACVHCDKAFKRQFDLLRHLRTHTQERAFQCEFCEKAFTTSAALKIHYRVHISLNEKPAKVYSCTVADCGKRFPSMRKLDMHTRTHLSSVSYICSLCSKSFSSKAGFSAHKHHPQDREFDMVRPFLEPPVKLDSNDTEEADKIDEYSKRSHQCSVCGLKMQKLSHLQQHEATHTGEKPFKCSICFRSYTTKSSLNLHHKIHTAEKPHACKICDSKFITQSVLQRHMISHSNERKFACPYCSERFKSNDNCKNHILMHARSLLASPEISPLQEAYPEPSSPAPEASSPETVAKPFIAVVQSPQKNASPKFIQLEMVKDCKKHTHKNLTIETVTSSPKKSSKKSLARSLKQISQIGHRCGECGKTFYKASDLQRHTRTHTKEKPFECSLCSKGFALMSTLGQHMKTHDTLRETFGCQVCGKKYSSRKVLLVHLRIHTGERPFQCGVCKKTFRTSGHKISHMKAHHKKRK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00314551; iTF_00316186; iTF_00311227; iTF_00312008; iTF_00313677; iTF_00312845;
90% Identity: iTF_00314551; iTF_00316186; iTF_00311227; iTF_00312008; iTF_00313677; iTF_00312845;
80% Identity: -