Basic Information

Insect: Cheilosia pagana
Gene Symbol: Zfy2
Assembly: GCA_936435595.1
Location: CAKZFE010000057.1:1828427-1831396[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 20 0.0024 0.22 12.3 0.2 3 23 105 126 104 126 0.97

2 20 0.00062 0.056 14.2 1.8 1 23 132 154 132 154 0.98

3 20 0.00011 0.01 16.5 1.3 2 23 164 185 163 185 0.97

4 20 9.7e-05 0.0087 16.7 0.8 1 23 191 214 191 214 0.97

5 20 0.0042 0.38 11.6 1.0 1 19 246 264 246 266 0.96

6 20 1.1e-05 0.00097 19.7 0.2 1 23 274 296 274 296 0.98

7 20 1.4e-06 0.00013 22.5 0.8 1 23 302 325 302 325 0.98

8 20 0.13 12 6.8 2.1 1 23 335 358 335 358 0.91

9 20 1.5e-06 0.00013 22.4 2.4 3 23 450 470 448 470 0.97

10 20 5.4e-07 4.8e-05 23.8 0.8 1 23 476 498 476 498 0.99

11 20 0.0056 0.5 11.2 0.1 1 23 509 533 509 533 0.95

12 20 0.0038 0.35 11.7 2.2 1 20 539 558 539 560 0.94

13 20 0.065 5.9 7.8 2.7 1 23 598 620 598 620 0.97

14 20 9.1e-06 0.00082 19.9 5.0 1 23 626 648 626 648 0.98

15 20 4.3e-05 0.0039 17.8 1.2 1 23 654 676 654 676 0.96

16 20 0.00028 0.026 15.2 2.3 1 23 682 704 682 704 0.97

17 20 1.8e-07 1.6e-05 25.3 2.9 1 23 802 824 802 824 0.98

18 20 3.5e-05 0.0031 18.1 0.3 1 23 830 852 830 852 0.99

19 20 0.00019 0.017 15.8 0.3 3 23 861 881 859 881 0.98

20 20 0.00012 0.011 16.4 4.8 1 23 887 909 887 910 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	20	0.0024	0.22	12.3	0.2	3	23	105	126	104	126	0.97
2	20	0.00062	0.056	14.2	1.8	1	23	132	154	132	154	0.98
3	20	0.00011	0.01	16.5	1.3	2	23	164	185	163	185	0.97
4	20	9.7e-05	0.0087	16.7	0.8	1	23	191	214	191	214	0.97
5	20	0.0042	0.38	11.6	1.0	1	19	246	264	246	266	0.96
6	20	1.1e-05	0.00097	19.7	0.2	1	23	274	296	274	296	0.98
7	20	1.4e-06	0.00013	22.5	0.8	1	23	302	325	302	325	0.98
8	20	0.13	12	6.8	2.1	1	23	335	358	335	358	0.91
9	20	1.5e-06	0.00013	22.4	2.4	3	23	450	470	448	470	0.97
10	20	5.4e-07	4.8e-05	23.8	0.8	1	23	476	498	476	498	0.99
11	20	0.0056	0.5	11.2	0.1	1	23	509	533	509	533	0.95
12	20	0.0038	0.35	11.7	2.2	1	20	539	558	539	560	0.94
13	20	0.065	5.9	7.8	2.7	1	23	598	620	598	620	0.97
14	20	9.1e-06	0.00082	19.9	5.0	1	23	626	648	626	648	0.98
15	20	4.3e-05	0.0039	17.8	1.2	1	23	654	676	654	676	0.96
16	20	0.00028	0.026	15.2	2.3	1	23	682	704	682	704	0.97
17	20	1.8e-07	1.6e-05	25.3	2.9	1	23	802	824	802	824	0.98
18	20	3.5e-05	0.0031	18.1	0.3	1	23	830	852	830	852	0.99
19	20	0.00019	0.017	15.8	0.3	3	23	861	881	859	881	0.98
20	20	0.00012	0.011	16.4	4.8	1	23	887	909	887	910	0.96

Sequence Information

Coding Sequence: atgcaaaacaataccGACTTATTTACTCCACTTCCAGTGGATATATCCACTCCAAATGCTCTTCTCTACCAGCTGAATGATTCGGACGAGAAATTCCTAAAGTCCACCGAATTCTATGCCTTCGAAATGGATGGTTTCACAGTGCCCGAAATCGATACAATATCCGGCCTAAGTCCGATTCCGGAGGAGGCAAGTTGTTCACTGCACGTACCTCCGATAGACACGCTATTCTCTTCTGTCGATCCAGCTCATTCACAGCAAAAGTACACATGCACTGATTTGCCTTCATCAGCTTTATCGAAACAAGTGGCATGTGACCTGTGTTCGGAGACGTTTTCCTCGGCGCAGGTGTTGCGCCTTCACAGACGAGTCCAACATATTTTGACCAAGGAATTCCGCTGTCGCAAGTGTCCGGCATCATTCAATTTCGAATCCAATTTGCACCTCCATCTGGCTTCGCATGTACCCAGTAGTTGTAGCACAAACAAGGAGTGTCCCGAGTGCAAGATGTCGTTCAAACGAATTTCCAGCTTCAAAGGCCACCTAAAGTCCCATCAGACCAACGATCTCTTTAAATGCAACCGCTGTGAAAAGGAGTTCGAATCGAGGGGCTACTATGAGAAGCACTTGGCAACGGCACACAAGCCCGGCGTCGATGGGACCGTTGAGGAGATTCTGGCCAGCGTCACCAGCAATGCCAGAAGTCGAATAAAGCCCAAGAAAGTGCAAGGCAAATACCAATGTCAGACGTGTGGAAAGGTCTTTCTAAAGCCGTGTCTGCTGAAGCGCCACGAGGTCTGTCATACGGGTGCGAAGCCATTTCAGTGCACAGAGTGCGCCCAAGCGTTCACCCAGAAACCATCCTTAGCAAGGCACATGCTGTTGCATCAAGGCGTCAAGGACTTTAAGTGTCCCAAGTGCAGCTTGAGCTTTGCACAGAAGAATAATCTCATTGTGCATATCAAGCGCACTCATCCAATGCGCCCCAACTTGGATAGCATGTTTGCGTGCGATTTCTGTTCATGTGTGTTCACGAAACTGAACAGCGTCAATCGGCATAAGGCACTTATGCACCCGAGGGGCGAAACCGCTGAAAACGATGGAtttaacgacgacgacgatgacaatgTAAATGTCGCCAAGGTAATGGAGCAGCTGAAGAGCTTTCAAGAGTCCATGAACATTATGGACATGCAACCTCCAGCGCTGGAACTTTCGCTGTTGAAACCACCATCGCCGGGACCAAAGATACGCACAGTGACAGTGGTGGATACATTGAATCCGAACAAAGAGAAGACCTTCAAGACGGTGAAAGAAATCTCCTACAAGGGACAACGCACCTTGGCCTGCATGCACTGTGATAAGGCCTTCAAGAGACAATTCGATTTGCTAAGACACCTTCGAACTCACACCCAGGAGCGGGCATTCCAATGTGAATTCTGCGAAAAAACCTTCTCTACAAGTGCTGCTCTTAAAGTCCATTACCGAGTTCACGTTTCATTGAACGAAAAGCCAGCAAAAGTGTATGCCTGCACGGTAGCCGATTGTGGAAAGCGATTCCCATCGATGCGCAAGCTGGACATGCACACAGGAACTCACTCGAGCTCCGTGTCGTACATTTGTTCGCTGTGCTCGAAAAGCTTCTCGTCCAAAGCCGGCTTCTCGGCCCATAAGCACCATCCACAGGATAAAGAGTTTGACATGGTTCGACCGTTCCTAGAGCCGCCAGTCAAGCTAAACTCCAATGACACCGAAGAGGCAGACAAAATCGAGGAATACTCGAAAAGAAGCCACCAATGCAGTGTCTGcggattaaaaatgcaaaagttaTCACACTTGCAACAGCACGAGGCTACACACACCGGCGAGAAACCGTTCAAGTGCTCCATATGCTTCAGGTCTTTTACAACGAAAAGTTCCCTCAATCTGCACCACAAAATCCACACCGCTGAAAAGCCTCACGCGTGTAAAATCTGCGACTCAAAGTTTATAACACAATCAGTCCTCCAGCGACACATGATTTCGCACAGCAACGAGCGCAAGTTCGCCTGTCCATACTGCAGTGAACGCTTCAAGAGCAACGACAACTGCAAGAATCACATTTTAATGCACGCCCGCAGTCTATTGGCCTCCCCCGAAATAAGCCCACTTCAAGAGGCTTATCCCGAGCCGTCCTCGCCTGCGCAAGAAGCTTCTTCTCCCGAGACTGTCGCCAAACCCTTCATCGCAGTTGTTCAAAGCCCCCAGAAGAACGCATCGCCAAAGTTCATCCACCTGGAGATGGTCAAGGACTGCAAAAGGCACACTCACAAGAACCTCACCATCGAAACGGTGACCAGTTCGCCGAAAAAGTCGTCTAAGAAATCACTGGCGCGATCATTGAAACAGATTAGCCAAATCGGCCATCGGTGTGGTGAGTGTGGTAAAACGTTTTACAAAGCCAGTGATCTGCAACGGCATACGCGGACGCATACCAAGGAGAAGCCCTACGAATGTAGTATCTGCTCGAAAGGGTTTGCCTTGTTGTCCACTTTGGGGCAGCATATGAAAACTCATGACACGCTGAGGGAGACCTTTGGCTGTCAGGTGTGCGGCAAGAAGTACAGCTCGCGGAAGGTGCTGCTAGTGCATCTGAGAATCCACACCGGTGAGCGGCCGTTTCAGTGTGGTGTATGCAAAAAGACCTTTCGAACGTCGGGGCATAAGATTTCGCACATGAAGGCGCATCACAAGAAGAGGAGATGA
Protein Sequence: MQNNTDLFTPLPVDISTPNALLYQLNDSDEKFLKSTEFYAFEMDGFTVPEIDTISGLSPIPEEASCSLHVPPIDTLFSSVDPAHSQQKYTCTDLPSSALSKQVACDLCSETFSSAQVLRLHRRVQHILTKEFRCRKCPASFNFESNLHLHLASHVPSSCSTNKECPECKMSFKRISSFKGHLKSHQTNDLFKCNRCEKEFESRGYYEKHLATAHKPGVDGTVEEILASVTSNARSRIKPKKVQGKYQCQTCGKVFLKPCLLKRHEVCHTGAKPFQCTECAQAFTQKPSLARHMLLHQGVKDFKCPKCSLSFAQKNNLIVHIKRTHPMRPNLDSMFACDFCSCVFTKLNSVNRHKALMHPRGETAENDGFNDDDDDNVNVAKVMEQLKSFQESMNIMDMQPPALELSLLKPPSPGPKIRTVTVVDTLNPNKEKTFKTVKEISYKGQRTLACMHCDKAFKRQFDLLRHLRTHTQERAFQCEFCEKTFSTSAALKVHYRVHVSLNEKPAKVYACTVADCGKRFPSMRKLDMHTGTHSSSVSYICSLCSKSFSSKAGFSAHKHHPQDKEFDMVRPFLEPPVKLNSNDTEEADKIEEYSKRSHQCSVCGLKMQKLSHLQQHEATHTGEKPFKCSICFRSFTTKSSLNLHHKIHTAEKPHACKICDSKFITQSVLQRHMISHSNERKFACPYCSERFKSNDNCKNHILMHARSLLASPEISPLQEAYPEPSSPAQEASSPETVAKPFIAVVQSPQKNASPKFIHLEMVKDCKRHTHKNLTIETVTSSPKKSSKKSLARSLKQISQIGHRCGECGKTFYKASDLQRHTRTHTKEKPYECSICSKGFALLSTLGQHMKTHDTLRETFGCQVCGKKYSSRKVLLVHLRIHTGERPFQCGVCKKTFRTSGHKISHMKAHHKKRR

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00315369;
90% Identity: iTF_00315369;
80% Identity: -