Basic Information

Insect: Cheilosia variabilis
Gene Symbol: -
Assembly: GCA_951230905.1
Location: OX579678.1:61620006-61625737[-]

Transcription Factor Domain

TF Family: BTB
Domain: zf-C2H2|ZBTB
PFAM: PF00651
TF Group: Zinc-Coordinating Group
Description: The BTB (for BR-C, ttk and bab) [6] or POZ (for Pox virus and Zinc finger) [1] domain is present near the N-terminus of a fraction of zinc finger (Pfam:PF00096) proteins and in proteins that contain the Pfam:PF01344 motif such as Kelch and a family of pox virus proteins. The BTB/POZ domain mediates homomeric dimerisation and in some instances heteromeric dimerisation [1]. The structure of the dimerised PLZF BTB/POZ domain has been solved and consists of a tightly intertwined homodimer. The central scaffolding of the protein is made up of a cluster of alpha-helices flanked by short beta-sheets at both the top and bottom of the molecule [2]. POZ domains from several zinc finger proteins have been shown to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes including N-CoR and SMRT [5, 3, 4]. The POZ or BTB domain is also known as BR-C/Ttk or ZiN.
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 27 3 9.1e+02 0.9 0.0 66 103 99 136 94 140 0.92

2 27 3.1 9.5e+02 0.8 0.0 66 102 157 193 152 197 0.92

3 27 3.1 9.5e+02 0.8 0.0 66 102 215 251 210 255 0.92

4 27 3.1 9.5e+02 0.8 0.0 66 102 273 309 268 313 0.92

5 27 3.1 9.5e+02 0.8 0.0 66 102 331 367 326 371 0.92

6 27 1.4 4.2e+02 2.0 0.0 65 104 388 427 381 430 0.92

7 27 2.3 6.9e+02 1.3 0.0 66 103 445 482 438 485 0.91

8 27 5.8 1.8e+03 -0.0 0.0 66 102 501 537 497 540 0.91

9 27 2.2 6.6e+02 1.3 0.0 65 103 558 596 551 599 0.91

10 27 2.6 8e+02 1.1 0.0 66 103 615 652 610 655 0.92

11 27 2.6 7.8e+02 1.1 0.0 66 103 671 708 666 711 0.92

12 27 4 1.2e+03 0.5 0.0 66 103 727 764 720 767 0.91

13 27 2.6 7.8e+02 1.1 0.0 66 103 783 820 778 823 0.92

14 27 2.7 8.2e+02 1.0 0.0 66 103 839 876 833 880 0.91

15 27 2.2 6.6e+02 1.3 0.0 65 103 929 967 922 970 0.91

16 27 3.1 9.5e+02 0.8 0.0 66 102 986 1022 981 1026 0.92

17 27 2.5 7.7e+02 1.1 0.0 65 103 1043 1081 1036 1085 0.91

18 27 2.4 7.4e+02 1.2 0.0 66 103 1102 1139 1097 1143 0.92

19 27 3 9.1e+02 0.9 0.0 66 103 1158 1195 1153 1199 0.92

20 27 3.5 1e+03 0.7 0.0 66 103 1216 1253 1210 1257 0.91

21 27 3.1 9.5e+02 0.8 0.0 66 102 1272 1308 1267 1312 0.92

22 27 2.5 7.7e+02 1.1 0.0 65 103 1329 1367 1322 1371 0.91

23 27 2.4 7.4e+02 1.2 0.0 66 103 1388 1425 1383 1429 0.92

24 27 1.7 5.3e+02 1.6 0.0 66 103 1444 1481 1439 1486 0.92

25 27 2.6 7.8e+02 1.1 0.0 66 103 1502 1539 1497 1542 0.92

26 27 3 9.1e+02 0.9 0.0 66 103 1558 1595 1553 1599 0.92

27 27 0.48 1.5e+02 3.4 0.0 66 108 1616 1658 1610 1660 0.92

#	of	c-Evalue	i-Evalue	score	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	27	3	9.1e+02	0.9	66	103	99	136	94	140	0.92
2	27	3.1	9.5e+02	0.8	66	102	157	193	152	197	0.92
3	27	3.1	9.5e+02	0.8	66	102	215	251	210	255	0.92
4	27	3.1	9.5e+02	0.8	66	102	273	309	268	313	0.92
5	27	3.1	9.5e+02	0.8	66	102	331	367	326	371	0.92
6	27	1.4	4.2e+02	2.0	65	104	388	427	381	430	0.92
7	27	2.3	6.9e+02	1.3	66	103	445	482	438	485	0.91
8	27	5.8	1.8e+03	-0.0	66	102	501	537	497	540	0.91
9	27	2.2	6.6e+02	1.3	65	103	558	596	551	599	0.91
10	27	2.6	8e+02	1.1	66	103	615	652	610	655	0.92
11	27	2.6	7.8e+02	1.1	66	103	671	708	666	711	0.92
12	27	4	1.2e+03	0.5	66	103	727	764	720	767	0.91
13	27	2.6	7.8e+02	1.1	66	103	783	820	778	823	0.92
14	27	2.7	8.2e+02	1.0	66	103	839	876	833	880	0.91
15	27	2.2	6.6e+02	1.3	65	103	929	967	922	970	0.91
16	27	3.1	9.5e+02	0.8	66	102	986	1022	981	1026	0.92
17	27	2.5	7.7e+02	1.1	65	103	1043	1081	1036	1085	0.91
18	27	2.4	7.4e+02	1.2	66	103	1102	1139	1097	1143	0.92
19	27	3	9.1e+02	0.9	66	103	1158	1195	1153	1199	0.92
20	27	3.5	1e+03	0.7	66	103	1216	1253	1210	1257	0.91
21	27	3.1	9.5e+02	0.8	66	102	1272	1308	1267	1312	0.92
22	27	2.5	7.7e+02	1.1	65	103	1329	1367	1322	1371	0.91
23	27	2.4	7.4e+02	1.2	66	103	1388	1425	1383	1429	0.92
24	27	1.7	5.3e+02	1.6	66	103	1444	1481	1439	1486	0.92
25	27	2.6	7.8e+02	1.1	66	103	1502	1539	1497	1542	0.92
26	27	3	9.1e+02	0.9	66	103	1558	1595	1553	1599	0.92
27	27	0.48	1.5e+02	3.4	66	108	1616	1658	1610	1660	0.92

Sequence Information

Coding Sequence: ATGAGAGCTACGATTTTGGCAGTTGTCCTGGCAGCAGGGATATGTGCTGCGGAAGTCATCGGGAGTCAACGGAGCTTGTGCACCGGAATAACGGACGGATCTTTTGTTGGAGATCCGGATTCATGTTCCAATTTCTTCATCTGTTACAACTCCGAGGCTGTCAGTCAAAGTTGTGAGCAGGGTAGTTACTTTGACAGCACGAATCTGTACTGCATACCGGATACGGATAATGTTTGCCCGCAACCGCCGGAGTGCAGCGAAAATGgagcttacagtccacaccccACCGAGTGTGCCCTCTTTTACATTTGCTACAATGGGACGCTGGTGGAGCAGAGCTGTGACGTTGGCAGCTACTTTAACAGCACGAATCTGTACTGCATCCCGGATACGGATAATGTTTGCCCCAGCCCGCAACCGTCGGAGTGCAGCGAAAATGgagcttacagtccacaccccACCGAGTGTGCCCTCTTTTACATTTGCTACAATGGGACGCTGGTGGAGCAGAGCTGTGACGTTGGCAGCTACTTTAACAGCACGAATCTGTACTGCATCCCGGATACGGATAATGTTTGCCCCAGCCCGCAACCGCCGGAGTGCAGCGAAAATGgagcttacagtccacaccccACCGAGTGTGCCCTCTTTTACATTTGCTACAATGGGACGCTGGTGGAGCAGAGCTGTGACGTTGGCAGCTACTTTAACAGCACGAATCTGTACTGCATCCCGGATACGGATAATGTTTGCCCCAGCCCGCAACCGCCGGAGTGCAGCGAAAATGgagcttacagtccacaccccACCGAGTGTGCCCTCTTTTACATTTGCTACAATGGGACGCTGGTGGAGCAGAGCTGTGACGTTGGCAGCTACTTTAACAGCACGAATCTGTACTGCATCCCGGATACGGATAATGTTTGCCCCAGCCCGCAACCGCCGGAGTGCAGCGAAAATGgagcttacagtccacaccccACCGAGTGTGCCCTCTTTTACATTTGCTACAATGGGACGCTGGTGGAGCAGAGCTGTGACGTTGGCAGCTACTTTAACAGCACGAATCTGTACTGCATCCCGGATACGGATAATGTTTGCCCCAGCCCGCAACCGCCGGAGTGCAGCGAAAATGGAGCTTACATTCCACACCCCACCGAGTGTGCCCTCTTTTACATTTGCTACAATGGGACGCTGGTGGAGCAGAGCTGTGACGTTGGCAGCTACTTTAACAGCACGAATCTGTACTGCATACCGGATACGGATAATGTTTGCCGGCAACCGTCGGAGTGCGGCGAAAATGGAGCTTACATTCCACACCCCACCGAGTGTGCCCTCTTTTACATTTGCTACAATGGGACGCTGGTGGAGCAGAGCTGTGACGTTGGCAGCTACTTTAACAGCACGAATCTGTACTGCATACCGGATACGGATAATGTTTGCCCGCAACCGTCGGAGTGCGGCGAAAATGgagcttacagtccacaccccACCGAGTGTACCCTCTTTTACATTTGCTACAATGGGACGCTGGTGGAGCAGAGCTGTGACGTTGGCAGCTACTTTAACAGCACGAATCTGTACTGCATACCGGATACGGATAATGTTTGCCCCAGCCCGCAACCGCCGGAGTGCAGCGAAAATGGAGCTTACATTCCACACCCCACCGAGTGTGCCCTCTTTTACATTTGCTACAATGGGACGCTGGTGGAGCAGAGCTGTGACGTTGGCAGCTACTTTAACAGCACGAATCTGTACTGCATACCGGATACGGATAATGTTTGCCCGCAACCGTCGGAGTGCGGCGAAAATGgagcttacagtccacaccccACCGAGTGTGCCCTCTTTTACATTTGCTACAATGGGACGCTGGTGGAGCAGAGCTGTGACGTTGGCAGCTACTTTAACAGCACGAATCTGTACTGCATACCGGATACGGATAATGTTTGCCCGCAACCGCCGGAGTGCAGCGAAAATGgagcttacagtccacaccccACCGAGTGTGCTCTCTTTTACATTTGCTACAATGGGACGCTGGTGGAGCAGAGCTGTGACGTTGGCAGCTACTTTAACAGCACGAATCTGTACTGCATACCGGATACGGATAATGTTTGCCCGCAACCGTCGGAGTGCGGCGAAAATGGAGCTTACATTCCACACCCCACCGAGTGTGCCCTCTTTTACATTTGCTACAATGGGACGCTGGTGGAGCAGAGCTGTGACGTTGGCAGCTACTTTAACAACACGAATCTGTACTGCATACCGGATACGGATAATGTTTGCCCGCAACCGTCGGAGTGCGGCGAAAATGgagcttacagtccacaccccACCGAGTGTGCCCTCTTTTACATTTGCTACAATGGGACGCTGGTGGAGCAGAGCTGTGACGTTGGCAGCTACTTTAACAGCACGAATCTGTACTGCATACCGGATACGGATAATGTTTGCCCGCAACCGTCGGAGTGCGGCGAAAATGGAGCTTACAGTTCACACCCCACCGAGTGTGCCCTCTTTTACATTTGCTACAATGGGACGCTGGTGGAGCAGAGCTGTGACGTTGGCAGCTACTTTAACAGCACGAATCTGTACTGCATCCCGGATACGGATAATGTTTGCCCCAGCCCGCAACCATCGGAGTGCAGCGAAAATGgagcttacagtccacaccccACCGACACGAATCTGTACTGCATACCGGATACGGATAATGTTTGCCCCAGCCCGCAACCGCCGGAGTGCAGCGAAAATGGAGCTTACATTCCACACCCCACCGAGTGTGCCCTCTTTTACATTTGCTACAATGGGACGCTGGTGGAGCAGAGCTGTGACGTTGGCAGCTACTTTAACAGCACGAATCTGTACTGCATACCGGATACGGATAATGTTTGCCCGCAACCGTCGGAGTGCGGCGAAAATGGAGCGTACAGTCCACACCCCACCGAGTGTGCCCTCTTTTACATTTGCTACAATGGGACGCTGGTGGAGCAGAGCTGTGACGTTGGCAGCTACTTTAACAGCACGAATCTGTACTGCATACCGGATACGGATAATGTTTGCCCCAGCCCGCAACCGCCGGAGTGCAGCGAAAATGGAGCTTACATTCCACACCCCACCGAGTGTGCCCTCTTTTACATTTGCTACAATGGGACGCTGGTGGAGCAGAGCTGTGACGTTGGCAGCTATTTTAACAGCACGAATCTGTACTGCATCCCGGATACGGATAATGTTTGCCCCAGCCCGCAACCGTCGGAGTGCAGCGAAAATGgagcttacagtccacaccccACCGAGTGTGCACTCTTTTACATTTGCTACAATGGGACGCTGGTGGAGCAGAGCTGTGACGTTGGCAGCTACTTTAACAGCACGAATCTGTACTGCATACCGGATACGGATAATGTTTGCCCGCAACCGTCGGAGTGCAGCGAAAATGgagcttacagtccacaccccACCGAGTGTGCCCTCTTTTACATTTGCTACAATGGGACGCTGGTGGAGCAGAGCTGTGACGTTGGCAGCTACTTTAACAGCACGAATCTGTACTGCATCCCGGATACGGATAATGTTTGCCCCAGCCCGCAACCGTCGGAGTGCAGCGAAAATGgagcttacagtccacaccccACCAAGTGTGCCCTCTTTTACATTTGCTACAATGGGACGCTGGTGGAGCAGAGCTGTGACGTTGGCAGCTACTTTAACAGCCCGAATCTGTACTGCATACCGGATACGGATAATGTTTGCCCGCAACCGTCGGAGTGCAGCGAAAATGGAGCGTACAGTCCACACCCCACCGAGTGTGCCCTCTTTTACATTTGCTACAATGGGACGCTGGTGGAGCAGAGCTGTGACGTTGGCAGCTACTTTAACAGCACGAATCTGTACTGCATACCGGATACGGATAATGTTTGCCCCAGCCCGCAACCGCCGGAGTGCAGCGAAAATGGAGCTTACATTCCACACCCCACCGAGTGTGCCCTCTTTTACATTTGCTACAATGGGACGCTGGTGGAGCAGAGCTGTGACGTTGGCAGCTATTTTAACAGCACGAATCTGTACTGCATCCCGGATACGGATAATGTTTGCCCCAGCCCGCAACCGTCGGAGTGCAGCGAAAATGGAGCTTACAGTCCTCACCCCACCGAGTGTGCACTCTTTTACATTTGCTACAATGGGACGCTGGTGGAGCAGAGCTGTGACGTTGGCAGCTACTTTAACAGCACGAATCTGTACTGCATACCGGATACGGATAATGTTTGCCCGCAACCGTCGGAGTGCAGCGAAAATGgagcttacagtccacaccccACCGAGTGTGCCCTCTTTTACATTTGCTACAATGGGACGCTGGTGGAGCAGAGCTGTGACGTTGGCAGCTACTTTAACAGCACGAATCTGTACTGCATCCCGGATACGGATAATGTTTGCTCCAGCCCGCAACCGTCGGAGTGCAGCGAAAATGgagcttacagtccacaccccACCGAGTGTGCCCTCTTTTACATTTGCTATAATGGGACGCTGGTGGAGCAGAGCTGTGACGTTGGCAGCTACTTTAACAGCACGAATCTGTACTGCATACCGGATACGGATAATGTTTGCCCGCAACCGTCGGAGTGCGGCGAAAATGGAGCGTACAGTCCACACCCCACCGAGTGTGCCCTCTTTTACATTTGCTACAATGGGACGCTGGTGGAGCAGAGCTGTGACGTTGGCAGCTACTTTAACAGCACGAATCTGTACTGCATCCCGGATACGGATAATGTTTGCCCCAGCCCGCAACCGTCGGAGTGCAGCGAAAATGGATCTTACAGTCCACACCCCACCGAGTGTGCCCTCTTTTACATTTGCTACAATGGGACGCTGGTGGAGCAGAGCTGTGACGTTGGCAGCTACTTTGACAAAACAGAACTCTATTGCGTACCGGACACAAACAACATCTGTCAACAGCCACAGTGCACCACAAATGGGGCAATAAGTCCCTATCCCGGGCAGTGTGCTTTGTTCTACATCTGCTACGATGGCTTACTTGTGGAACAAACCTGCGGCGTCGGTAGTTACTTTGACGCAGAGAATTTGTACTGCTTACCCGACTCTGACAACGTCTGTTGGCCATCGACGACAACCGAAAAGTCGTCATGCCCATGCGTTGGAGGCCACACGAATGGCGAGTTTGTCGCCAGCCCGGACTGCTGCTATTCGTACTATGTGTGCAGCGATGGCGAACTTGTGGAACAGAACTGTGGATATGGAAATTATTTTGACAACAGCATTAAGCGGTGTGAAAAAGATGTCACCGGTGAGTGTTGGCCGTCGTCCAGTTTTACAACAACTACTACCCAGGCGCCTTGTACTTCATGCAATGAGGGTGACTTCGTTGCCAACGATGACAGTTGCTACGCATTTTCTCTGTGTGCCCAAGGTGCGCTTGTGGAACTAAGCTGTGGCTATGGAAACTATTTCGACAGGGTCACTAAGGTGTGCGAAAGGGACATCGAAGGGAAGTGCTGGACAACAACAGAGCCCTCCGATTGTTAG
Protein Sequence: MRATILAVVLAAGICAAEVIGSQRSLCTGITDGSFVGDPDSCSNFFICYNSEAVSQSCEQGSYFDSTNLYCIPDTDNVCPQPPECSENGAYSPHPTECALFYICYNGTLVEQSCDVGSYFNSTNLYCIPDTDNVCPSPQPSECSENGAYSPHPTECALFYICYNGTLVEQSCDVGSYFNSTNLYCIPDTDNVCPSPQPPECSENGAYSPHPTECALFYICYNGTLVEQSCDVGSYFNSTNLYCIPDTDNVCPSPQPPECSENGAYSPHPTECALFYICYNGTLVEQSCDVGSYFNSTNLYCIPDTDNVCPSPQPPECSENGAYSPHPTECALFYICYNGTLVEQSCDVGSYFNSTNLYCIPDTDNVCPSPQPPECSENGAYIPHPTECALFYICYNGTLVEQSCDVGSYFNSTNLYCIPDTDNVCRQPSECGENGAYIPHPTECALFYICYNGTLVEQSCDVGSYFNSTNLYCIPDTDNVCPQPSECGENGAYSPHPTECTLFYICYNGTLVEQSCDVGSYFNSTNLYCIPDTDNVCPSPQPPECSENGAYIPHPTECALFYICYNGTLVEQSCDVGSYFNSTNLYCIPDTDNVCPQPSECGENGAYSPHPTECALFYICYNGTLVEQSCDVGSYFNSTNLYCIPDTDNVCPQPPECSENGAYSPHPTECALFYICYNGTLVEQSCDVGSYFNSTNLYCIPDTDNVCPQPSECGENGAYIPHPTECALFYICYNGTLVEQSCDVGSYFNNTNLYCIPDTDNVCPQPSECGENGAYSPHPTECALFYICYNGTLVEQSCDVGSYFNSTNLYCIPDTDNVCPQPSECGENGAYSSHPTECALFYICYNGTLVEQSCDVGSYFNSTNLYCIPDTDNVCPSPQPSECSENGAYSPHPTDTNLYCIPDTDNVCPSPQPPECSENGAYIPHPTECALFYICYNGTLVEQSCDVGSYFNSTNLYCIPDTDNVCPQPSECGENGAYSPHPTECALFYICYNGTLVEQSCDVGSYFNSTNLYCIPDTDNVCPSPQPPECSENGAYIPHPTECALFYICYNGTLVEQSCDVGSYFNSTNLYCIPDTDNVCPSPQPSECSENGAYSPHPTECALFYICYNGTLVEQSCDVGSYFNSTNLYCIPDTDNVCPQPSECSENGAYSPHPTECALFYICYNGTLVEQSCDVGSYFNSTNLYCIPDTDNVCPSPQPSECSENGAYSPHPTKCALFYICYNGTLVEQSCDVGSYFNSPNLYCIPDTDNVCPQPSECSENGAYSPHPTECALFYICYNGTLVEQSCDVGSYFNSTNLYCIPDTDNVCPSPQPPECSENGAYIPHPTECALFYICYNGTLVEQSCDVGSYFNSTNLYCIPDTDNVCPSPQPSECSENGAYSPHPTECALFYICYNGTLVEQSCDVGSYFNSTNLYCIPDTDNVCPQPSECSENGAYSPHPTECALFYICYNGTLVEQSCDVGSYFNSTNLYCIPDTDNVCSSPQPSECSENGAYSPHPTECALFYICYNGTLVEQSCDVGSYFNSTNLYCIPDTDNVCPQPSECGENGAYSPHPTECALFYICYNGTLVEQSCDVGSYFNSTNLYCIPDTDNVCPSPQPSECSENGSYSPHPTECALFYICYNGTLVEQSCDVGSYFDKTELYCVPDTNNICQQPQCTTNGAISPYPGQCALFYICYDGLLVEQTCGVGSYFDAENLYCLPDSDNVCWPSTTTEKSSCPCVGGHTNGEFVASPDCCYSYYVCSDGELVEQNCGYGNYFDNSIKRCEKDVTGECWPSSSFTTTTTQAPCTSCNEGDFVANDDSCYAFSLCAQGALVELSCGYGNYFDRVTKVCERDIEGKCWTTTEPSDC

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -