Basic Information

Gene Symbol
-
Assembly
GCA_948107745.1
Location
OX443564.1:39668796-39672137[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 20 2.5 2.9e+02 2.9 0.3 2 23 183 205 182 205 0.94
2 20 6.6 7.7e+02 1.6 0.7 1 23 212 236 212 236 0.83
3 20 0.027 3.2 9.1 6.4 2 19 247 264 246 267 0.92
4 20 5.8 6.8e+02 1.7 2.9 2 23 278 299 277 299 0.87
5 20 0.058 6.8 8.0 0.0 3 23 308 329 307 329 0.95
6 20 0.0024 0.28 12.4 1.9 2 23 336 357 335 357 0.96
7 20 0.012 1.4 10.2 2.7 1 23 363 386 363 386 0.97
8 20 3.2e-05 0.0037 18.3 1.3 1 23 392 415 392 415 0.97
9 20 2.3 2.7e+02 3.0 0.1 1 19 424 442 424 445 0.84
10 20 0.0021 0.25 12.6 0.2 1 23 462 484 462 484 0.97
11 20 0.0031 0.36 12.1 1.5 1 23 489 511 489 511 0.98
12 20 0.095 11 7.4 0.2 1 23 527 551 527 551 0.97
13 20 2.5e-06 0.00029 21.8 4.0 1 23 557 579 557 579 0.98
14 20 0.0015 0.17 13.1 0.9 1 23 585 608 585 608 0.95
15 20 0.0017 0.2 12.8 0.4 2 23 614 636 613 636 0.95
16 20 2.5e-06 0.00029 21.8 0.7 2 23 640 662 639 662 0.96
17 20 3.1e-05 0.0036 18.3 0.2 1 23 668 691 668 691 0.95
18 20 0.0053 0.62 11.3 1.8 1 23 697 719 697 719 0.97
19 20 0.00021 0.024 15.7 5.6 1 23 725 747 725 747 0.98
20 20 0.0013 0.16 13.2 0.1 1 23 753 778 753 778 0.94

Sequence Information

Coding Sequence
ATGTCCATAGAGTGCTTACGATGTAGAACGCCTTTAAGTAAGGATTGCCAGTTGATCTTCGATGAAACTGGCATCGAACTGCAACTGGACAAACTTCTCATTGAGCACTTTGGAATTTACGTCGAAAAGGATGACTGCACGACGCAGGCTCTTTGTGAAGAATGTGTAAATGAATTAATTGAACTGTACGATATAACACAGCGAGATCAGGAGCTACAATCTGCTGCAAACGAAACAAGCAATGGCAGTGAATCACAGGAATTCAAAGAAGAAGTGGAACTCATTATTGAAGAAACGGAAGTCGACTTGGAAAATGAAGAGGTTTACGAAAATACACAGGAACCTGAACAGGAGTATGAAGAGGAGGtggaaatggaaaatgaattgaTCGCAGTGGAAAATAACGAAGAGTTCTTCGAATTTGAAAATGAAGTAAATATCGGTAACAATCAGTGTCTGGATGAATTGGAAGGTATCACCACACAACAGTACTGTCAAAAAGTCATCAAAAGTGAACTGGAAGAAGTCGACTGTGATCAAACTACTGTTTGCAGGTTATGCGAGGAAGTCTTGAAGAGTCACACTGCTGTAATGATGCACGTAGCCACAAATCACGAAACTGATTCCAAACAGTACCCATGCATTATATGCAATGTGGAGTGTTTTGATTCAATGAAAGATCTAGCACATCACATTGTACTGAAGCATTACGATCTCGAGGCAATCACCATTTACTGCATTTGTCCTGAGTGCGATAAGAGATTTTCAAACTTTACTCTGTTCAATAAACATTCGTGCCACAAGGCAAGCACAGGAAGTCGCCTATTACAGGAGTGTTTTGAATGTTCAAGGCAGTTTAACTCGAATAAGAGATATCGTTTCCACTTGCAATTCCATTTAAAGAAACGACGACCAAAAGCTTGCTTTATCTGTGACATTCTTTTTTCCGATGAAAACGATTTCTACGAGCACATAATGTATGCGCACGAGAAGAAGGACAAACTGATATGCAAAAAATGCGATCGAATTTGTTCAACGCAACAATTGTACGATAACCACATCAAAGTACACGACGCTGTTCGAACTTTCTATTGCGAATATTGCACCAGAtcgtatttatacaaacaaatgtTGATGAATCACATAAAACGCCAACATACCGAAAAAGACTGCTACCAATGCACTATCTGCAAAAAATCTCTAGCCAATAAGCATGTCCTAGCGAGGCACATGAAACTAATACATAACGAAGAAACAAATGAAAGTGTTTACACGTGTTCCACGTGTGGTCTTCTGGCAGCTACTAATGACGACATAAAGGAACATTTTAACGAAAGCATCTGTCCAGATGCAAAACTCACTACACAGTGCTTGGCGGTGGCGTTTGCTTGTGAATTTTGTGAACAAGCCTATAACAGTGTGGAGAATTTGAATTTGCATCGCAAAATTCACGTAAAAAAGCGCTACTCATGTTGGATCTGTAAAACGGATTATACAGAATTTAAGAAACTGAAAACCCACATCCTGACGCACAATAATGTTGAGCCATTACAGGATACGTTCCCTATCAACAGGCACTACGTGTGTGATTTTAATTTGTGCGATCAAACCTATCTAACATGGCCATCGCTAAGCGCGCACAAAATGCGCCATTCCGTCAATGCCAAGTTTACATGTGAAATTTGCAATCAGACATTCAGGACAAAAACGCATTTAAGCAACCACCAAAGAGGTCACGATAACAACGACCAATTCCCTTGTCAGTTTTGCCCGAAAATGTGCTCTTCGCAAATGTCTCTAGCGGTTCATGTCGCACGCAAGCACAACAACAATTGTAAAACATGCCCAACCTGCAATTCGACATATTCCACCGAAGAAGCACTTAAAGATCACATCGATAAATACCACGTCGAATTGGAATGTAAGCAGTGCGGTAAAATCACGAAAAATAAGCGAAATCTTGAGACACACATACGAATGGTTCATGCCAATGTGAAGAGGTACTTCTGTCCGACATGCAACAAGGGCTACTACAACAAAGGCGATCTAAAGGTTCATGTGCGAGCGGCTCACTCGGACCAGCACAAGTTCAAATGTCAGCACTGTGATTTTATGACGAGCTACGAGGCATCGTACAATGCTCACCTTTTACTGCATGAATCTAAAAAACCATTCAAATGTGACATATGCTCGAAAGAATTCACCAGAAAAACATGCTTCAAATTGCATCTACTGAGGCATGCGGATGTTAAACCGTTTGCTTGTCCGGTTGAAGATTGCGACAGGAGCTTTGTAACGAGAGGGATTCTTAACACACACCTGCGTGACAGTCATCCAGAGACCGAAGGCAAAGCCAAAAGAGCATCACCACGGGCTGTAAAGCGAAATCGGCAAAAAGCCGCCGATCCTGTGCGCAATACGAAGTCTAGGAAATACGTTATCGCCGATGAGAGTTCAGGCAGTACTCCCTTGGAACTCAACGATGAAGAAGGTGGTATGATTTTTTATGATGCATCAAATACAGATCAGGAAATTGTACTTGAATGCATTGAAGAGGATAATGACTTGATTGAGGATTTAAATCAATGTGATGTTGTTAATTAG
Protein Sequence
MSIECLRCRTPLSKDCQLIFDETGIELQLDKLLIEHFGIYVEKDDCTTQALCEECVNELIELYDITQRDQELQSAANETSNGSESQEFKEEVELIIEETEVDLENEEVYENTQEPEQEYEEEVEMENELIAVENNEEFFEFENEVNIGNNQCLDELEGITTQQYCQKVIKSELEEVDCDQTTVCRLCEEVLKSHTAVMMHVATNHETDSKQYPCIICNVECFDSMKDLAHHIVLKHYDLEAITIYCICPECDKRFSNFTLFNKHSCHKASTGSRLLQECFECSRQFNSNKRYRFHLQFHLKKRRPKACFICDILFSDENDFYEHIMYAHEKKDKLICKKCDRICSTQQLYDNHIKVHDAVRTFYCEYCTRSYLYKQMLMNHIKRQHTEKDCYQCTICKKSLANKHVLARHMKLIHNEETNESVYTCSTCGLLAATNDDIKEHFNESICPDAKLTTQCLAVAFACEFCEQAYNSVENLNLHRKIHVKKRYSCWICKTDYTEFKKLKTHILTHNNVEPLQDTFPINRHYVCDFNLCDQTYLTWPSLSAHKMRHSVNAKFTCEICNQTFRTKTHLSNHQRGHDNNDQFPCQFCPKMCSSQMSLAVHVARKHNNNCKTCPTCNSTYSTEEALKDHIDKYHVELECKQCGKITKNKRNLETHIRMVHANVKRYFCPTCNKGYYNKGDLKVHVRAAHSDQHKFKCQHCDFMTSYEASYNAHLLLHESKKPFKCDICSKEFTRKTCFKLHLLRHADVKPFACPVEDCDRSFVTRGILNTHLRDSHPETEGKAKRASPRAVKRNRQKAADPVRNTKSRKYVIADESSGSTPLELNDEEGGMIFYDASNTDQEIVLECIEEDNDLIEDLNQCDVVN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00312864;
90% Identity
iTF_00312864;
80% Identity
-