Basic Information

Insect: Cheilosia pagana
Gene Symbol: Rreb1_1
Assembly: GCA_936435595.1
Location: CAKZFE010000052.1:1758800-1764567[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 0.031 2.8 8.8 0.8 1 21 235 255 235 257 0.93

2 14 0.00029 0.026 15.2 0.2 1 23 267 289 267 289 0.98

3 14 8.4e-06 0.00076 20.0 5.2 1 23 295 317 295 317 0.98

4 14 0.028 2.5 9.0 2.8 2 19 518 535 518 535 0.97

5 14 2.5 2.3e+02 2.8 0.6 1 19 581 599 581 602 0.83

6 14 0.0078 0.7 10.7 0.1 1 23 755 777 755 777 0.97

7 14 0.00016 0.014 16.0 1.7 1 23 786 808 786 808 0.99

8 14 0.00041 0.037 14.7 2.0 1 23 814 837 814 837 0.97

9 14 0.00084 0.075 13.8 2.1 1 23 1182 1205 1182 1205 0.95

10 14 7.6e-05 0.0068 17.0 0.3 2 23 1512 1533 1511 1533 0.97

11 14 0.13 11 6.9 6.3 1 23 1539 1562 1539 1562 0.97

12 14 2.7 2.4e+02 2.7 6.3 1 23 1653 1675 1653 1676 0.95

13 14 0.0074 0.67 10.8 0.5 3 23 1725 1745 1723 1745 0.96

14 14 0.0012 0.11 13.2 4.8 1 23 1751 1773 1751 1773 0.99

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	0.031	2.8	8.8	0.8	1	21	235	255	235	257	0.93
2	14	0.00029	0.026	15.2	0.2	1	23	267	289	267	289	0.98
3	14	8.4e-06	0.00076	20.0	5.2	1	23	295	317	295	317	0.98
4	14	0.028	2.5	9.0	2.8	2	19	518	535	518	535	0.97
5	14	2.5	2.3e+02	2.8	0.6	1	19	581	599	581	602	0.83
6	14	0.0078	0.7	10.7	0.1	1	23	755	777	755	777	0.97
7	14	0.00016	0.014	16.0	1.7	1	23	786	808	786	808	0.99
8	14	0.00041	0.037	14.7	2.0	1	23	814	837	814	837	0.97
9	14	0.00084	0.075	13.8	2.1	1	23	1182	1205	1182	1205	0.95
10	14	7.6e-05	0.0068	17.0	0.3	2	23	1512	1533	1511	1533	0.97
11	14	0.13	11	6.9	6.3	1	23	1539	1562	1539	1562	0.97
12	14	2.7	2.4e+02	2.7	6.3	1	23	1653	1675	1653	1676	0.95
13	14	0.0074	0.67	10.8	0.5	3	23	1725	1745	1723	1745	0.96
14	14	0.0012	0.11	13.2	4.8	1	23	1751	1773	1751	1773	0.99

Sequence Information

Coding Sequence: ATGTTGAAAACACCAATTAAAAAGCAATTAACAGACATTCCACTGCGCAAAATGGATCGACGCGACTCAACAACATCAGACTCATCTGTCGAACCCATGGACTTGGGACGtacaacagaaaagaaaaaacaaaccaacacaACAGCATTACAGATGCCAACAGCAGTAACACTTAAAGATGCCATTTTATCAGATGCCAATAAAAAATACCCCATACGTCATGAATCTGATGCCGACGAATCAGATGACAAAGACAGAGATCACCAGCGCCGATCACACAGTCAACATCACTACCATCATCGTCGGCGCGGTGGTAATAGTGGGCGCGATAAACGTACCGTCCACTTGGAATGCACCGACACTCCACATTCGTTGCGAAAGAAATTTCGCTTCAGCAGCACGCAAAACCAATCGCTACCAGAGACTGTGATCAATTTGAAACAACAGAAAACATCGAACAATGATTCCACGTTATCGGGGAAGTCAGCAAATCTAACCGCTACAACGAACAACAATGAATCTGGCTTTGTGGACGCCAGCAGCAGTCATGTTCTAAACACATCCGTTTCATCGGCGACATCATCcacatcgtcgtcatcgtcgtcgccgACATCCTCATCGTCGGCGGCGGCATCACCATCCGCCAGTAATATCGCCGTTTCGAGTCCCGAATCGGGCGTGGGCGAACGTGACGACATGAAGTACCTTTGCCCAATTTGTGAGGTGGTATCGGCGACACCGCATGAATTTACCAATCACATCAGATGTCATAATTATTCATCTGGGGACACCGAAAATTTCACCTGCCGCATTTGCTCTAAGGTTCTATCGTCTGCCTCGTCACTGGATCGACACGTTCTGGTGCACACTGGTGAACGGCCTTTCAACTGCAAATATTGCCAACTGACATTCACCACAAATGGCAACATGCATCGTCACATGCGAACCCACAAACAGCACCAGCAACACTACCATCGAAATTCAAATGGTACAAAGGGGGGTggaagtggtggtggtggtgcgacGATTGCGGGTGCTAATGGCGGCAACTCCGGCTTAATACCAAATTTACCATcaaacgaccaatcggctgctgtgCCCTCCAAACCAACTGTCGTTACCAATGGTGTTGTTATTAACAGCAATGGTGACACAATTggaggaggtggtggtggtggcgaaAGTTACGAAAGTGATGGTGGTTGCTCAACGGATTCATCGAGTGCCATCAGCCAAAGttccaataacaacaacaacagcaatacgaacaacaaaaacattagCAATTTTAAGCGCAAGAGCACCGACAGCTTGGATGACATGGCCATGATGAAGCGACGCGTGAAGAccaccatcaacaacaacaatatcaTCGATAACAACATGCACACCGAAAAGAGTACCATCGAAGAGGCTGACGAAGACTTGAAGCAGCAGCACCAgccgcaacaacaacagaagcTCTTTTGCCCGGTATGCAATCGCAGTGACTTTGTGGGGATGCTGGCATTGGGCTCCCATATGGACTGCGATCATTCGGATATTCCTGCAAAGTGTCGTCATTGTGACGTTGTCTTTAAGACACACAAGCAATTGAACGTTCATCCATGCACGAGTAAGCTTAAGATCACGCACGGCTTTAAGGACCTTACGTTTGTGGACTTTTCGAGCGAAAAGTTTCCCCTCATTGCCAAGTCTTTATGTGAGCAGAGCCTAAGGACGTCAGTGGGTAGTCAAAAGTTTGAGTGCTCCAAGTGCTATCGAGCGTTTCCATGCGCCAGTTCTGTAGAAATACACGAGAAAGAGTGTGCCACATCAGGGATGAATTTGTACGTCGATGCACATGACTTCTCTGTTCGCAAGCAGCGATCGTATAGCGAGAGTTCAGGTGGCGCTGACGATGACGACAATCGTCGGGAGGAGTTCTTTGCCCGTTTGTACTTAAAGAACAAATCTACAGTACAAAGTATGACCAGCTTATCGTTGTCGTCCCCCTCGCTGTCTGATGTTAAGTCGTCCGAGTTGGACAAGACACCTGTAAAAATGTCCCAGTCCCAGCTAGACCAATACCACGACACTAAAGAGCTAGCCGATATTCAATCCATTCTCAATATAACATCATCGTCATCAACGAGCAATTTCCTTCGCAACTTTGAGAACTCTGTGAACACACCGATCAGTAATTACGGAACCGAAAATGGCGAAGAGGAAGCTCAAGATGCATTCACTTCCGAGTTTCGCAAGATGAAGTTGCGCGGGGAGTTCCCGTGTAAACTGTGCACGGCAGTGTTCCCCAACCTCCGCGCTCTAAAAGGCCACAACCGCATACATCTTAGCGCAGCAGGTCCCGGTCCATATCGCTGCAATATGTGCACATATTCAATCCACGATAAGGCGGCACTGGTGCGTCATATGCGAACACACAACGGCGACAGGCCATACGAGTGCGCCATCTGTAACTACGCGTTCACAACAAAAGCCAACTGCGAACGACATTTGCGCAATCGGCACGCCAAAACCACACGCGACGATGTAAAGCGCGCTATTATCTATCATCCATCGGAAGATTCGAACTGCGATGACGCCATGAAGAAGCTGCACATGTTCTCCTCGCCGGAATTCGATCAAGACGACATGGAGCAACACCATCCACCAAAGGACCGATCCACTCCGGTATCACATCTAAAAGAAATGCTGCAGTCCGAGTCGAAGCCGCTCAAGATTCAAGTGAAGAGCTTGGAGAAGTTAATCGACAAGGCGGCACCATCGTTTAATCAATCAGATGAGATCGAGGAGTTGGAGAAAAATGATGTCCAGCACGATAAGACCAGTCGACCGATTGATCTTAGCATGGATGCATTGGATTTGAGCAAAAAGCCAGTGAAAGCGCCTAAAATTCCAGAAAAACCACCACAATCTCCGCTACCGCCTCAGATACAACCTGGACGTGCACAACCCCCCGAAGAGCAAAACATCGACATGCATCTTTTGGAGAACAACCAACAGTTGCTGCTGGCCCAACAGCGATTGTTGAACGCCGCCATGCCGAAAATGGATACCGCGCACTATTTGCAGCTCTCGCAGCTCTATCGCAACTTGGTGTTGCAGCCATTTCACCCTTTTTTCCTACAAAACTCATTCCTGTCGAACAACATCAGTGATCTAAATAAATTCGCTCCGCTGATGAATCCACTCTTTGATCATCCGGCAGCCTCTGAGACCTTCGCCGCCGGCAACTACAACCAAAGTATGCAGCCAAAGATAGTACCAGAAGAAGCCAACTTAATGCTGAAGCAGTCCAATTCACGGGCTCACTCGCCGAGCCCTGCTAAGAACCTATTAATACCGCGGAACCTCACTCCATCTTCGACACAAATGCCGCCCATGCCACGCAGCCATTCGCATATGGGGCCCATGACGGGACCACATTCCACAGGAATGATCCCATCATCGGTGTCCAACACAGGCCCGGTGAAGATGGTCATTAAAAACGGTGTACTCATGCCCAAGCAGAAGCAGCGTCGCTATCGCACGGAGCGGCCCTTTGCCTGTGAACATTGCTCCGCTCGCTTCACCTTGCGTTCGAATATGGAACGCCACATCAAGCAACAGCACCCCCAGTATTGGGCTCAGCGGCAACGTAGCGGTCATCACATCATGCGTGGACGTGCCAACAGTAGTTCGGTGCTGTCGCACATGCAACCAACTCACTCGCCCTTGGAAGCTCCACATCAGATTAGCGGCAGTGGCATTATCAATCACCATATGAGTGCTATTCCCGATCAGGTAAAATATGCCATTCTGGCCAAACAGCTCAAGGCCCGCAAGGAGACAGACATTCTGCAGCAAGCCCTGTCCCAAGGCTCTGGCAGCGTGTTAACACAGAACCCCACAACCGCGGCCATCAGTAATCTTCGAAAATCACTCAGCTCCTCGTCGAACACAAATAATGGTAGCATAGAGGACGATGATCCCAAGCTCATTATCGATGAAGATGACGAAAAGGAAGACGATCgcgaagatgatgatgatgatgatgaagacgaGGAAGATTGTAAGGTAGAAAATTTGACGCAAGGCTACCAAGAAATCAATGAAGCTGCAAAAAAAGCTGCCAAGTCCATTTTGGAACAGGCCATGAAAGCTGGCAGCGCCAAGAGCTCCTTTAACCCGAACGGCAACGATGTAGAAACTCCAATTGCAAAGGATTTCAGCCTCAAACTGTCGAAAAATATGATTGCTCAAGCTGAGTCTGTTGGCAAATTCCTCAAAGAAGTCGCCAGTTCTCCGTTCAAGGACGAGTCAAATGACCTCGCTTCGGTGTCAAGACTCGTTGACAACGCCACCAATGCGATGTCTTTCAACAACTACTTTCGGCCCAGTGATGTTGTCAACCAAGCGGAACAAAGTGACGAAGAGGGTTTGGTTGCATCGGGCAGCGCATCCGAAAGCAATAACTCTGGCCCCGAGGATATGCCCGGCGCGCtagaaccaaaaaagaaatctGCCTACAGCTCGGCGCCAAATCGAGTTTCGTGCCCCTATTGCCAGCGAATGTTCCCCTGGTCTAGTTCACTGCGGCGACACATTCTAACACACACCGGTCAGAAGCCCTTCAAATGTTCACATTGCCCCTTGCTCTTCACCACTAAGAGCAACTGCGATCGCCACCTACTTCGAAAGCACGGTAATGTCGAATCGGCTGTGTCGCTGTACGTCCCGATCGAGGATGTTAACGAGCCATTGCCAGTTCCCAAGTCTGTCGAGGAGATTGAGCTGCAACACCAACAACAGCTGCAGCAGcagagggaacaaaaaaaactcgaagAACAAAAGGAACTTGAAGAACAGAAACAAGTGGTTCAGGAGAATAATGAACAGGCAACCCCAACGACCATAAACTCGGGTTGCAAGGCAGAGCCAGTCACACAAATTGTCTCGTCGTCTGAGCTGCCGTTTAAGTGTCACCTATGCGACAGTTCGTTTGCCGAACGATTTCAGTGCCTCGATCATATCAAGATCCATCATGCTCAGGAGTTCGCGCTGCTGCTTTCCAAGGGCGCCATTGACAGCGAAGCCGATGTCAACAGTCAAGTACAGTCAACCGAGGATGACGAAAAACGGGACGAAAGCCGTGGCAAATACCCCGACTATACCAACCGCAAGGTTATCTGCGCCTTCTGCGTTCGTCGTTTCTGGTCCACGGAAGATCTGCGTCGTCATATGCGGACTCACTCGGGCGAGAGGCCATTTCAGTGCGACATCTGTTTGCGCAAGTTCACCCTGAAGCACAGCATGCTGCGTCACATGAAGAAACACAGCGGCGGCAGTCATTCCAGTAACGGTGCCGCCAACGCCGCCAACAGTGGTTCCGATATATCCGACGATGAACAGCCCCCAGCCAGTGTTATGCTGGCAACCACACTTCGCAACCACAAAATCCAGGAGCTATTCTCGAAGGCCAACAGCGAGTGGCGCAACAATCGACTCTCAGGCGAGCACAAGGAGAACATTGAAGAGCACAACAACCAGTCCGATCTAATTGGCAACCTGCTTGGCATTAGCGACCAGGGCATCCTCAACAAGCTTCTCTCGTCCGCAGATGAGGCGGCCAAGTTTTTAGGTGTCGACAAGTAA
Protein Sequence: MLKTPIKKQLTDIPLRKMDRRDSTTSDSSVEPMDLGRTTEKKKQTNTTALQMPTAVTLKDAILSDANKKYPIRHESDADESDDKDRDHQRRSHSQHHYHHRRRGGNSGRDKRTVHLECTDTPHSLRKKFRFSSTQNQSLPETVINLKQQKTSNNDSTLSGKSANLTATTNNNESGFVDASSSHVLNTSVSSATSSTSSSSSSPTSSSSAAASPSASNIAVSSPESGVGERDDMKYLCPICEVVSATPHEFTNHIRCHNYSSGDTENFTCRICSKVLSSASSLDRHVLVHTGERPFNCKYCQLTFTTNGNMHRHMRTHKQHQQHYHRNSNGTKGGGSGGGGATIAGANGGNSGLIPNLPSNDQSAAVPSKPTVVTNGVVINSNGDTIGGGGGGGESYESDGGCSTDSSSAISQSSNNNNNSNTNNKNISNFKRKSTDSLDDMAMMKRRVKTTINNNNIIDNNMHTEKSTIEEADEDLKQQHQPQQQQKLFCPVCNRSDFVGMLALGSHMDCDHSDIPAKCRHCDVVFKTHKQLNVHPCTSKLKITHGFKDLTFVDFSSEKFPLIAKSLCEQSLRTSVGSQKFECSKCYRAFPCASSVEIHEKECATSGMNLYVDAHDFSVRKQRSYSESSGGADDDDNRREEFFARLYLKNKSTVQSMTSLSLSSPSLSDVKSSELDKTPVKMSQSQLDQYHDTKELADIQSILNITSSSSTSNFLRNFENSVNTPISNYGTENGEEEAQDAFTSEFRKMKLRGEFPCKLCTAVFPNLRALKGHNRIHLSAAGPGPYRCNMCTYSIHDKAALVRHMRTHNGDRPYECAICNYAFTTKANCERHLRNRHAKTTRDDVKRAIIYHPSEDSNCDDAMKKLHMFSSPEFDQDDMEQHHPPKDRSTPVSHLKEMLQSESKPLKIQVKSLEKLIDKAAPSFNQSDEIEELEKNDVQHDKTSRPIDLSMDALDLSKKPVKAPKIPEKPPQSPLPPQIQPGRAQPPEEQNIDMHLLENNQQLLLAQQRLLNAAMPKMDTAHYLQLSQLYRNLVLQPFHPFFLQNSFLSNNISDLNKFAPLMNPLFDHPAASETFAAGNYNQSMQPKIVPEEANLMLKQSNSRAHSPSPAKNLLIPRNLTPSSTQMPPMPRSHSHMGPMTGPHSTGMIPSSVSNTGPVKMVIKNGVLMPKQKQRRYRTERPFACEHCSARFTLRSNMERHIKQQHPQYWAQRQRSGHHIMRGRANSSSVLSHMQPTHSPLEAPHQISGSGIINHHMSAIPDQVKYAILAKQLKARKETDILQQALSQGSGSVLTQNPTTAAISNLRKSLSSSSNTNNGSIEDDDPKLIIDEDDEKEDDREDDDDDDEDEEDCKVENLTQGYQEINEAAKKAAKSILEQAMKAGSAKSSFNPNGNDVETPIAKDFSLKLSKNMIAQAESVGKFLKEVASSPFKDESNDLASVSRLVDNATNAMSFNNYFRPSDVVNQAEQSDEEGLVASGSASESNNSGPEDMPGALEPKKKSAYSSAPNRVSCPYCQRMFPWSSSLRRHILTHTGQKPFKCSHCPLLFTTKSNCDRHLLRKHGNVESAVSLYVPIEDVNEPLPVPKSVEEIELQHQQQLQQQREQKKLEEQKELEEQKQVVQENNEQATPTTINSGCKAEPVTQIVSSSELPFKCHLCDSSFAERFQCLDHIKIHHAQEFALLLSKGAIDSEADVNSQVQSTEDDEKRDESRGKYPDYTNRKVICAFCVRRFWSTEDLRRHMRTHSGERPFQCDICLRKFTLKHSMLRHMKKHSGGSHSSNGAANAANSGSDISDDEQPPASVMLATTLRNHKIQELFSKANSEWRNNRLSGEHKENIEEHNNQSDLIGNLLGISDQGILNKLLSSADEAAKFLGVDK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01223735;
90% Identity: iTF_00314647;
80% Identity: -