Basic Information

Gene Symbol
hang
Assembly
GCA_963082955.1
Location
OY720145.1:35681239-35688179[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 17 0.042 4.1 8.4 1.3 3 23 252 273 251 273 0.93
2 17 0.016 1.6 9.7 2.7 1 23 444 467 444 467 0.91
3 17 0.0015 0.15 12.9 1.7 2 23 575 597 574 597 0.95
4 17 0.018 1.7 9.6 0.1 1 23 605 628 605 628 0.95
5 17 2.9e-05 0.0028 18.4 0.1 2 23 725 746 724 746 0.97
6 17 1.9e-05 0.0018 19.0 2.5 2 23 798 820 797 820 0.96
7 17 0.0043 0.42 11.5 0.3 2 23 829 851 828 851 0.95
8 17 0.00075 0.074 13.9 0.2 1 23 864 887 864 887 0.97
9 17 0.00032 0.032 15.1 1.0 1 23 915 937 915 937 0.99
10 17 0.0014 0.13 13.1 0.9 1 23 945 968 945 968 0.96
11 17 0.013 1.3 10.0 0.3 2 21 976 995 975 996 0.92
12 17 0.00013 0.012 16.3 0.5 3 23 1052 1072 1051 1072 0.98
13 17 6.1e-05 0.0061 17.3 0.2 1 23 1107 1129 1107 1129 0.98
14 17 6.4e-05 0.0063 17.3 0.2 2 23 1154 1176 1153 1176 0.93
15 17 0.077 7.5 7.6 0.2 2 19 1196 1213 1195 1215 0.93
16 17 0.0053 0.52 11.2 0.4 3 23 1231 1251 1231 1251 0.98
17 17 0.00083 0.082 13.8 0.9 1 23 1388 1410 1388 1410 0.97

Sequence Information

Coding Sequence
ATGACGGAAGAATCAATATTACGTGCACGTCAGAATTGCTGTCGCTTGTGCTTGGCTCCGGACAGCGAATGTATTTCGATTTTTAGCAGCTACGCGGCTGATAAGGAGCCCCTAGCTACCAAAATTCAATCATGTGTCAATATTAAGGTGTCTCCAATTGATCGGCTCTCACTGCGAATATGCCATGCTTGCATCAGCTACTTGAATTCGTGGCAGAGTTTCAAGAATCGTTGTGTTGCCTCACAGAACAAGCAACGTAGCTGGCTGGagatatcgaaaaaattcgaaaagaaacaaattggGGCAACCATACAGCTCACGGCTGCACCAGTGGGGATACCCCATGAAGAAATACCGACTGGAGGAGGGGGTGATGAACATGATACCAGTCCACTTGCCACATCGATTTTGGAAGGAATATCATCGCTGAAAAAGCGACGCTCCTTGACGGTTTACCCAATTCCGGTGCACATTAAAGATGAACCAATGGACGAGGAGGAATACGATCCAAAACACGACGAGTCCGACATTGATCCTACACTTTTCTTGGAACGCACCGAGGAGGAAGGCTCGGACAATCTGTCACAGAAGGAACAACATTTGGCCTCTTTGGGCCTGAAACAAGCAACGACTTCTGTAAATCCATTAAATTATTTGgctGAATACAGCTTCGATGGAGATAAGATTCCACCGCCTGCAGTCGACAAGTCGCTCGAAATCACCCCAGCAATCAATGAAGTTAAAGAGGCATCATGTCGTGCCTGCAATTTGAAATTCTCCACAAGAGCAAATGCCCGCCGTCATGAGCGCAACCTTCATCCACATCTCTTCACAAGTGTTACGCTCAGCACAACCCAACCTAAAGGGCTGAATATCGTCTCACCGATGCAACAAGTTATAAAAGGCGCTGGCCAAGTTATACGCGCCGCAATAAGGCCCGAGCAGCTTGGACTGTACGACTATGATCAACCGGAGAAATACCAGGAACTTCTAACCGAAGAAAAAGTAGCATTCATGCAGCGTCACGACGACTTTTTGCAGCAATACCAGAATATGACATGCAACTGCTGTCTCCGAACACATGCCACGTATAAGAACTTTATGGCTCACATGCGTAAGAAGTATCACTTGCTACCGCGCAATCTctgttttaaatgtttaaagcaAAACGATTCAAAGGCACTGTTTATATCGCATCTAAAGAAACGCAACTGTATCAACCTGTACAAGATCTACCACAGCCTGATTGATGCAGGCGTACTGAAGAAGGATGCGACTGGCTGCTCACCAGACAAGCTGCGTGCTAAAGAGCTGCTGGTAAACAAAATCTATGAGTGCAAGATTTGCTCAAAGCATTTCCGCTTGAAGTTGGAGTTCCGCAGTCACGTCTATGAGGAACATGCAGACTATCAAAAGAAAGATGTCTCGCCAGGTCATTGCGGATTTTGTGGGCTAGAGATTGAAGATCCTTTCGAGCGGAAGCGCCACTACAACAACATGGACTGCATAGTTATACTGCGATGCATTACGTGTGAAGAGAAGTTTGATAATCACCAGAAATTCTTGGATCATGTGTACTCCAAGCATTTAGCAAATAACAACGAAGCTCAGAAGAGCAATCTAATGAAGGAGCTGGCGGCCACAACAACGTCTACTGACAGCTCGCCATCGAAAAAGTCAGAAACGCCCTCAAAGCCACAGTTCTTTTCCCGTCTACCTCAAAGCTGCAATATTTGCGGTCAACATTACAACAACTATAACAATGTTTTGCGCCACATGGAGTCCAAGCATCCGGACCAACTGCCGCAGACGTACAAGTGTACCCGGTGCCTGGTGGGTTATCCGCGCTTGATGAACCTCCGTGAGCACATGATCGAGGTACATGGTATGAAGGTGGACAAGGTGCGAAACAATAGCTTTGAATATATTGTAGACTCGCCTACAGTGCAGGGAAGTGCACTTCGACCCGGAGAAAAGATTACAGCCGATGCGTACACTGGGCGGTATGATTACGTAATGAAAGACTTGATGTCCATAACCAACGGTGGCACAGCCGGAGCTGAGGGCCCAAATGAAAACGAAGATGATGGTGATCAGTCCGATTCGCCCATTCCAAAGAAACTGAAGCTAGAAGCCGGCACCATGGTTGCAGTTGGCACCGCCAACCTAAAAGAATGTCCCATATGCAGTGCTGTCTTCAACAACAATATTGGCCTCTCCAATCACATGCGTACTCATACAGCTACAGAAACTGCAAGTGGCGGAGGGACAGTCACTGGCGGAGAGGAGCAGCTACCTGACGAAGACGAGGAGGTGGCAGCAAAGAAGCCGATTGATCCGCTTTTTAAGAGAAGTCTAGAGTTGGCGGCCGATCGTCGCTTTCGTCGCATGCGATGCCGCATTTGCCAGAAACGCTTTTCCTCGAAGAAGAGCTATCGCCGCCACATGCTGGTCGATCATCAAATTCGCAACGTGCAGTTCATAAAGTGCAAGCTCTGCAACGCCGAATTCGCTTACGAGAAAGGACTCAAAGTGCACATGTTCAAGATACACAATACCTTGTTGAAGGACGAAATGATTGTCAAACAATACGAATGCGATATATGTTCGATTGTGTACAGGACCGAGGAGCAGCTGCTGATGCATAAGAAATCGGTTCACGGTAATGAGAGTGCTCAGGCTGAAGACGAGCTCCCGCAATCGATTGAGCAGACAACAGAATCATCAGCACCGCTGTACTGGTACCAGTGCCGCTATTGCCCGTCCAACTTTAATACAAACAAGAAGCTGGCCATTCACATAAACTCCCACTACGAGTTCGACTCGAACGACTACTCCTGCAAGGACTGTGGCAATGTGTACAGTGGTCGCAAGAGTCTGTGGGTGCATCGCTACAAGAAGCATCCGCCGGTGGCTGATCCGTCAGAGTGTTCGCTCTGCAAGAAGATCTTTTTCGACAAGCAAATGCTGGAGAATCATGCCCAGTCGTGTGCCAAGAAGTCCAAGGTTGGCATATCTGAAACTGAGGTCTCATCTTCTTTCTTCCAGCATAAAACCGGAGACGATGACGATATAAATGATCACCAGCAGTCGGAGCAATCCGCTATTGGGGAGAGTGCGCCAAATTTGAAGATCAAACTACCCGAGGTCGCGTGTACCATTTGTGCGCAAAAATTCACGGACCAGGACCTCTTTACCAAACACATCCAGATGCACGAGATGGAGTTGTATACCGACAATCCGCTGGCCGCTATGTTCGACACCGGACCCGCTGATCCAAATCAATTCTACTTGGATCGAGTCAACGACAATGGGGAGTATGTGTGCGATATCTGTACAAAGGCGTTCGCCCAAATGACTGCGCTCAAGGTCCACCGCAAGTGGCATTTTCGAGGTGATAGCAAACAGacTCCAGCCGATGCAAACGCGCCAAAGACCATGAAACGCAAGCGTGAACTTAAATGCGATTACTGTCCGTCAACATTCATCAGCTCCAACAACCTCCGACGTCACATAGCCGAGCTGCACAAATCGGAAATATCCAACTGGCCGGAACCGCCGAAAATCGATCCCGAAAAGTATCTGCAATGTGGCAAGTGTGACCTGAAGTTCGAAAACAAGAAAGAATGGATCGAACATAAGGTGAACGAAGCGAAGATTGCCAAGCCGTTTGGACCTTTCCAGTGGGGCTGCGAGATTTGTGGTGTTTACCTGTCACGTCGCGAAAAGCTCATACATCACATGATGGCACACATAAAAGAGTCCAATGGTCGGGCGAGTCAGGTTGAGGGTGAGAACTATCCGGGTGAGAGTAACTCCCAGGACTCTGAATCTTCGAGTCATCCAGAGGCATCTGAACAGCAAAGACCAGATGAAGACGATGAAGAAGAGGAGGAAGAGGAcgaagaagaggaagaggaagaaGACCTCGAAGCTGacgaagaagaaacagaagaaaCAGCTGACACAGTCAACCATGATGACAATGCCAACGACGGACAAGATGAGCACGAGCAACAATCGCAACTAAGGCAACGACTGCAGCGTGAATCGAACGACGACAGCAATGACTCAAGTGACCAGAGCTCCGATTCGGATGATTCATCGTCTGATGAGGAAGAACCAGAAGCTCCCCAATCACGCGACGACTTTAAGAAGCGATTTTCGTGCGATTTATGTCAGGTTTTCTTTGACACATCAACGGAACTGCAAAAGCATGTCACTAGTCATTTCCTCAACGGACCCGGTTCAGTCACGCTCACCACAATCACAAAGGACAAACACAAGCACAAGCCACCAGCGAAAACCAAtcacgatgacgatgacgatgatgaaggtgatgatgatgatgaagacgacgacgatgatatGACCGAAACGGGCGTAGTGAACTCGTAA
Protein Sequence
MTEESILRARQNCCRLCLAPDSECISIFSSYAADKEPLATKIQSCVNIKVSPIDRLSLRICHACISYLNSWQSFKNRCVASQNKQRSWLEISKKFEKKQIGATIQLTAAPVGIPHEEIPTGGGGDEHDTSPLATSILEGISSLKKRRSLTVYPIPVHIKDEPMDEEEYDPKHDESDIDPTLFLERTEEEGSDNLSQKEQHLASLGLKQATTSVNPLNYLAEYSFDGDKIPPPAVDKSLEITPAINEVKEASCRACNLKFSTRANARRHERNLHPHLFTSVTLSTTQPKGLNIVSPMQQVIKGAGQVIRAAIRPEQLGLYDYDQPEKYQELLTEEKVAFMQRHDDFLQQYQNMTCNCCLRTHATYKNFMAHMRKKYHLLPRNLCFKCLKQNDSKALFISHLKKRNCINLYKIYHSLIDAGVLKKDATGCSPDKLRAKELLVNKIYECKICSKHFRLKLEFRSHVYEEHADYQKKDVSPGHCGFCGLEIEDPFERKRHYNNMDCIVILRCITCEEKFDNHQKFLDHVYSKHLANNNEAQKSNLMKELAATTTSTDSSPSKKSETPSKPQFFSRLPQSCNICGQHYNNYNNVLRHMESKHPDQLPQTYKCTRCLVGYPRLMNLREHMIEVHGMKVDKVRNNSFEYIVDSPTVQGSALRPGEKITADAYTGRYDYVMKDLMSITNGGTAGAEGPNENEDDGDQSDSPIPKKLKLEAGTMVAVGTANLKECPICSAVFNNNIGLSNHMRTHTATETASGGGTVTGGEEQLPDEDEEVAAKKPIDPLFKRSLELAADRRFRRMRCRICQKRFSSKKSYRRHMLVDHQIRNVQFIKCKLCNAEFAYEKGLKVHMFKIHNTLLKDEMIVKQYECDICSIVYRTEEQLLMHKKSVHGNESAQAEDELPQSIEQTTESSAPLYWYQCRYCPSNFNTNKKLAIHINSHYEFDSNDYSCKDCGNVYSGRKSLWVHRYKKHPPVADPSECSLCKKIFFDKQMLENHAQSCAKKSKVGISETEVSSSFFQHKTGDDDDINDHQQSEQSAIGESAPNLKIKLPEVACTICAQKFTDQDLFTKHIQMHEMELYTDNPLAAMFDTGPADPNQFYLDRVNDNGEYVCDICTKAFAQMTALKVHRKWHFRGDSKQTPADANAPKTMKRKRELKCDYCPSTFISSNNLRRHIAELHKSEISNWPEPPKIDPEKYLQCGKCDLKFENKKEWIEHKVNEAKIAKPFGPFQWGCEICGVYLSRREKLIHHMMAHIKESNGRASQVEGENYPGESNSQDSESSSHPEASEQQRPDEDDEEEEEEDEEEEEEEDLEADEEETEETADTVNHDDNANDGQDEHEQQSQLRQRLQRESNDDSNDSSDQSSDSDDSSSDEEEPEAPQSRDDFKKRFSCDLCQVFFDTSTELQKHVTSHFLNGPGSVTLTTITKDKHKHKPPAKTNHDDDDDDEGDDDDEDDDDDMTETGVVNS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00313703;
90% Identity
iTF_00316205;
80% Identity
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