Cnem004252.1
Basic Information
- Insect
- Chalcosyrphus nemorum
- Gene Symbol
- ZFX
- Assembly
- GCA_949716465.1
- Location
- OX454332.1:72303523-72306594[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 20 0.0013 0.11 13.1 0.2 2 23 105 127 104 127 0.96 2 20 0.00027 0.024 15.2 0.5 1 23 133 155 133 155 0.98 3 20 0.00015 0.014 16.0 0.5 2 23 164 185 163 185 0.97 4 20 0.00034 0.029 14.9 1.2 1 23 191 214 191 214 0.97 5 20 0.0019 0.16 12.6 1.0 1 19 246 264 246 266 0.94 6 20 6.5e-07 5.7e-05 23.5 0.7 1 23 274 296 274 296 0.98 7 20 3.4e-06 0.00029 21.2 3.7 1 23 302 325 302 325 0.98 8 20 0.0017 0.15 12.7 2.0 1 23 335 358 335 358 0.96 9 20 1.3e-06 0.00012 22.5 1.1 3 23 451 471 449 471 0.97 10 20 1.3e-06 0.00011 22.5 0.0 1 23 477 499 477 499 0.98 11 20 0.00019 0.017 15.7 0.3 1 23 510 534 510 534 0.97 12 20 0.00034 0.029 15.0 0.6 1 20 540 559 540 561 0.94 13 20 0.28 25 5.7 3.4 1 23 599 621 599 621 0.97 14 20 2.3e-05 0.002 18.6 1.8 1 23 627 649 627 649 0.98 15 20 1.6e-05 0.0014 19.1 1.2 1 23 655 677 655 677 0.97 16 20 2.5e-05 0.0022 18.5 3.2 1 23 683 705 683 705 0.98 17 20 1.2e-06 0.0001 22.7 0.2 2 23 802 823 802 823 0.98 18 20 2.8e-05 0.0024 18.4 0.8 1 23 829 851 829 851 0.98 19 20 3.5e-05 0.003 18.1 0.3 1 23 858 880 858 880 0.98 20 20 0.0015 0.13 12.9 6.9 1 23 886 908 886 909 0.95
Sequence Information
- Coding Sequence
- atgcaaaacaataCTGATCTGTTTACTCCACTGCCGGTGGACATATCCACTCCAAATGCACTGCTGTATCAGTTCAATGATGCAGCCGAAAAGTTCCTCAAATCTAACGAGTTCTATGCCTTCGAAATGGACAGCTTTATGGTACCTGAGATGGACTACATACCGCCAGTTATATCGAGTCTAAGTCCTATTCCTGAAGAGGCCAGTTGCTCTTTAAATGTACCTCCACTTGAGACGCTATTCTCACCGGTTGAACCCACAGAAACTACGCATAAATCCCCAAAGGATTGTCCAGTTCCACTGAAGCAACTCCCGTGCGACTTGTGTTCGGAGACATTCTCCTCGGCACAAGTGTTACGGCTACATAGACGAGTGCAACATATTTCAACAAAGGAATTCCGTTGTCGCAAATGTCCAGCGTCGttcaattttgagtcaaatttgCTCCTACATTTGGCATCGCATGTTCCGAGCTGTAGCACGAATAAAGAGTGTCCCGAGTGCAAGATGGTCTTCAAGCGGATCTCTGCTTTTAAGGGCCATCTGAAGTCACATCAGACAAGCGATCGATTCAAGTGTAATCGCTGTGACAAGGAGTTCGATCTGAAGGGCTACTACGAGAAGCACCTGGAAAAGGCCCACAAACAGGGCGCTGATGGTACGGTTGAAGAGATTTTGGCCAAAGTGGGCACGAGTGGCAGAAACCGTCCAAAGAGCAACAAATCCCAAGGGAAATATTTATGTCAAACTTGTGGGAAGAACTTTCCGAAGCCATGTCTTTTAAAACGTCACGAAGTCTGTCATACCGGAGCGAAACCATTTCAGTGCACCGAATGTGATCAGGGATTTACCCAGAAAACATCGTTAGCGAGGCACATGCTATTACACCAGGGCATAAAGGAATTCAAATGTCCAAAATGCAATTGTAGTTTTGCGCAAAAGAACAACCTGATAACACATATAAAGCGCACACATCCTATGGAACCGAATTTGGATGAGATGTTCGCATGCGAACACTGTCCGTGTGTTTTTACAAAGCTGAACAGTGCCAATCGTCATATGGCCATGATGCACCCAAAGAATGGTGACGCGCTTAATAACAGTGGGttcaacgatgatgatgatgacaatgttAACGTTGCCAAAGTAATGGAACAGCTAAAGAGCTTTCAGGAGTCTATGGGAATCATGGATATGCAGCCATCAGCATTAGAACTTTCCCTGATGAAGCCACCTTCGCCTGGACCGCAGGTTCAAGCGGTGACGTTAGTTGATACATTAAacccaaagaaagagaagactTATAAGGTAGTAAAAGAAATACTGTACAAGGGAGAGCGAACGATGGCGTGCATGTATTGTGATAAGCCGTTTAAGAGGCAGTTCGATTTGCTGAGACACTATCGTACGCACACAAAAGAGAAACCTTTTCCATGTGAAATCTGCGAAAAGAACTTCGCTACAAGTGCTGCTCTTAAAGTTCACATGAATATTCACAATTCCACGCAAGAACAGCCAGCAAAGGTCTATGTTTGCTCCGCCCCAGAGTGTGGAAAACGATTCTCTTCCATGCGGAGACTAGATATTCACACAAGAACTCACACGAGTTCGATCTCTTACATTTGTCCGGTGTGTTCGAAAACTTTTACATCGAAAGCCGGCTTCTCTGCACACAAGCATCAAACGGAGGATAAAGAATTTGATGCACTACGTCCGCTGCTGATGTCACCGATTAGAGTCGAAAAGGATAATGCTGAGGAGGAACATAAAGCCGAAGAGTACACCAAGAGAAATCATCAGTGCTTCGTCTGTGGcttaaaaatgcaaaagttaTCGCATTTGAGACAGCATGAAGCCACCCACAAGGGCGAGAAGCCTTTTAAGTGCGCCGTTTGCTTTAGATCATATACAACACAAAGTTCCCTTAACTTGCATTATAAGATTCACTCTGCCGAAAAGCCCCACGTCTGTGCCATCTGTAACTCCAAATTCATAACACAATCACTCCTCAAGCGACACATGATCTCACACAGCAATGAACGCAAATTCGAGTGCCCTTACTGCAATGAACGCTTCAAAACTAGTGATAACTGCAAGAATCATATCCTAACACATGCCCGCAACCTATTAGCAACGCCAGAACCGCCTCCCCTAGAGGACGAGCCTTTAGAAATATCAAACAATGCAGAGTCTCCTTCAGAATCGATCTCGAAGCCTCTTATTGCGGTTGTACAAAGCCCTCAAAAGAATCAATCACCAAAGTTCATACAACTGGAGATGGTTAAGAACTGCAAAAAGCACAGAcacacaaattttacaattgaaacaGTCGCCAACTCTCCAAAGAAGTCATCAAAGAAATCTCTAGCGCGATCTATGAAAAAGATTAATCAAATTGGTCGCCAATGCGGTGAATGTGGAAAGATATTCTATAAGGCAAGCGATCTGGAGCGCCATGCACGAACTCATACGAAAGAGAAACCATTCAATTGTAATTTATGTCCGAAACGATTTGCTTTGATGTCGACACTTGTGCAACATATGAAAACGCATGACACGCTTCGGGAGACATACGACTGCCAAGTGTGTGGTAAGAAGTATACATCGAGAAAGGTTTTGGTCGTACATTTGAGGATTCATACCGGCGAACGGCCATTTCATTGTGCTATTTGCAAAAAGACTTTTCGCACGTCGGGTCATAAAATATCACACATGAAGGCgcatcataaaaaaagaaagtga
- Protein Sequence
- MQNNTDLFTPLPVDISTPNALLYQFNDAAEKFLKSNEFYAFEMDSFMVPEMDYIPPVISSLSPIPEEASCSLNVPPLETLFSPVEPTETTHKSPKDCPVPLKQLPCDLCSETFSSAQVLRLHRRVQHISTKEFRCRKCPASFNFESNLLLHLASHVPSCSTNKECPECKMVFKRISAFKGHLKSHQTSDRFKCNRCDKEFDLKGYYEKHLEKAHKQGADGTVEEILAKVGTSGRNRPKSNKSQGKYLCQTCGKNFPKPCLLKRHEVCHTGAKPFQCTECDQGFTQKTSLARHMLLHQGIKEFKCPKCNCSFAQKNNLITHIKRTHPMEPNLDEMFACEHCPCVFTKLNSANRHMAMMHPKNGDALNNSGFNDDDDDNVNVAKVMEQLKSFQESMGIMDMQPSALELSLMKPPSPGPQVQAVTLVDTLNPKKEKTYKVVKEILYKGERTMACMYCDKPFKRQFDLLRHYRTHTKEKPFPCEICEKNFATSAALKVHMNIHNSTQEQPAKVYVCSAPECGKRFSSMRRLDIHTRTHTSSISYICPVCSKTFTSKAGFSAHKHQTEDKEFDALRPLLMSPIRVEKDNAEEEHKAEEYTKRNHQCFVCGLKMQKLSHLRQHEATHKGEKPFKCAVCFRSYTTQSSLNLHYKIHSAEKPHVCAICNSKFITQSLLKRHMISHSNERKFECPYCNERFKTSDNCKNHILTHARNLLATPEPPPLEDEPLEISNNAESPSESISKPLIAVVQSPQKNQSPKFIQLEMVKNCKKHRHTNFTIETVANSPKKSSKKSLARSMKKINQIGRQCGECGKIFYKASDLERHARTHTKEKPFNCNLCPKRFALMSTLVQHMKTHDTLRETYDCQVCGKKYTSRKVLVVHLRIHTGERPFHCAICKKTFRTSGHKISHMKAHHKKRK
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00389797;
- 90% Identity
- -
- 80% Identity
- -