Cruf019114.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Cerceris ruficornis
Gene Symbol
bab2
Assembly
GCA_963989415.1
Location
OZ022520.1:23864126-23866528[+]

Transcription Factor Domain

TF Family
BTB
Domain
zf-C2H2|ZBTB
PFAM
PF00651
TF Group
Zinc-Coordinating Group
Description
The BTB (for BR-C, ttk and bab) [6] or POZ (for Pox virus and Zinc finger) [1] domain is present near the N-terminus of a fraction of zinc finger (Pfam:PF00096) proteins and in proteins that contain the Pfam:PF01344 motif such as Kelch and a family of pox virus proteins. The BTB/POZ domain mediates homomeric dimerisation and in some instances heteromeric dimerisation [1]. The structure of the dimerised PLZF BTB/POZ domain has been solved and consists of a tightly intertwined homodimer. The central scaffolding of the protein is made up of a cluster of alpha-helices flanked by short beta-sheets at both the top and bottom of the molecule [2]. POZ domains from several zinc finger proteins have been shown to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes including N-CoR and SMRT [5, 3, 4]. The POZ or BTB domain is also known as BR-C/Ttk or ZiN.
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 1 3e-24 1.8e-21 77.5 0.0 4 98 217 307 214 309 0.94

Sequence Information

Coding Sequence
ATGAAGCAGGAGCCGGAAGATGAGGAGGACTGTTACCTCGAGGCGGCCGAATTGCCGTCACCTTCGCCGCCATCGTCTACCAATCGTCACACGGGATCCTCGCACCGTGTTCGTTCTCATGCGCGTAGCTTACGTGCTATGACCAATCCTAGCGCAGTGTGGGCGCATTTCGATCTATGCGCGAACGATCCGCTACGCGCACAGTGCCGTATCTGCGGGGCGGTCGTCGTCAGAGGGGGTGCGAATCCCCGACAATGCGGCACTACGAATCTTCATCGGCACCTTAGGGTACATCACGGTGGTAGACTCATTGGCAGTCGTTATCATGTGCTACAGTCACCATCTCAGGGCGGTACAACTGGGAAAACTATTAGAATAGCGGCACAATCGTTGGTAAGGCCGCATATTCGAAATATAGCACCGGCCCCTCTACCTCAACAAtcgcaacagcaacaacaaagGCAGCCAAAAACTCTCGTATTAAAAACTATACCGTTAAAAGTGAAGCAAGTCGCGCCAACTACAATTAAAATGCCTCCACGGCAAACCACCCAAGGAGTACCTCATAATATAGTTCATCAGCAACCTACCGAGGTTTGCCTGAGGTGGAACAGCTACCATAGTAACATGCAAAACAGTTTCCCGTCTCTGTTAGACACGGAACAATTTGTAGACGTTACGTTGGCTTGCGAGGGTCGTTCGTTAAAATGCCACAAAATGATATTGTCTTCGTGTAGCGACTACCTCGCAGACTTATTACGCGAAAATCCATGTCAGCATCCCATTATATTAATGAAAGATCTGAAATTTTGGGAAGTAGAAGCGCTAGTCAAATTCATGTATCGGGGTGAAGTTAACGTTGCCCATGACAAATTACCACAATTGTTAAACGCGGCCGAGGCGCTACAAGTGAAAGGATTAGCCGGGCCAAGTCCTTCTTCACAAaaTCCAAAGCCACCGCTACTTATTCCACAATCGAAGCCGTTAGTGTCTCAGCCAATAGTTCCTCGAGTGGTAACGGAGACCAAAGAAAATAAAGCTTCCGCTTCCGGAGTTTCTACACCGTCTAGTCCAAAACGTGCACAGAAACGGCAACAATCGGAGCCAATCGAGCCGAAGCCTTTTACGAAAATACGCTTACAACGACCAGTAACGCCAACATCACCGAATGCCACTGTAAAAATGGAGCCCCTGGATATACCTCTAAGTCCAACAGAAATATTTCCCGAAGGTAACGAGGACAGCTCGACCCCATCGAATTTCGAGAAATTAATGAGCCTACACGAGGATGATGATCCCGGAGGCAACGAAACGAATGACGGCGAAAGGGAAATAAATTTCTGTGAAATACCAGGTCCGCCGGATATAAACGATAGCGAAGACCAGATGGAATTTGTACCTACAGACTTTTTAGAGCAAGAACAAGATATAGTGGAGGAACCAGAAACGGCCTGCAACAAAGACAGTAAAGAGGACTCGAGAGATCAAAGTTCCGATGAGATCGAAAGTCCTGAGAGTAACAGCGTTGAGAAAGATAAATGTTCAAAGGAAAAGAAGCCGGTGTAA
Protein Sequence
MKQEPEDEEDCYLEAAELPSPSPPSSTNRHTGSSHRVRSHARSLRAMTNPSAVWAHFDLCANDPLRAQCRICGAVVVRGGANPRQCGTTNLHRHLRVHHGGRLIGSRYHVLQSPSQGGTTGKTIRIAAQSLVRPHIRNIAPAPLPQQSQQQQQRQPKTLVLKTIPLKVKQVAPTTIKMPPRQTTQGVPHNIVHQQPTEVCLRWNSYHSNMQNSFPSLLDTEQFVDVTLACEGRSLKCHKMILSSCSDYLADLLRENPCQHPIILMKDLKFWEVEALVKFMYRGEVNVAHDKLPQLLNAAEALQVKGLAGPSPSSQNPKPPLLIPQSKPLVSQPIVPRVVTETKENKASASGVSTPSSPKRAQKRQQSEPIEPKPFTKIRLQRPVTPTSPNATVKMEPLDIPLSPTEIFPEGNEDSSTPSNFEKLMSLHEDDDPGGNETNDGEREINFCEIPGPPDINDSEDQMEFVPTDFLEQEQDIVEEPETACNKDSKEDSRDQSSDEIESPESNSVEKDKCSKEKKPV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00306410; iTF_01065700; iTF_01065670; iTF_01068423; iTF_01069767; iTF_01069800; iTF_01068393; iTF_01069103; iTF_01069072; iTF_01066358; iTF_01066391; iTF_01067739; iTF_01070460; iTF_01067038; iTF_01067710; iTF_01070494; iTF_01067071; iTF_00684870; iTF_00684897; iTF_00961958; iTF_00961927; iTF_00963943; iTF_00962640; iTF_00962609; iTF_00963323; iTF_00963293; iTF_00963965; iTF_00964606; iTF_00964576; iTF_00361001; iTF_00360310; iTF_00361047; iTF_00360346; iTF_00232106; iTF_00228066; iTF_00228771; iTF_00228803; iTF_00228101; iTF_00220678; iTF_00220712; iTF_00223976; iTF_00224008; iTF_00224649; iTF_00224682; iTF_00227370; iTF_00227402; iTF_00216525; iTF_00232078; iTF_00216495; iTF_00217169; iTF_00217842; iTF_00217875; iTF_00217204; iTF_00218523; iTF_00218555; iTF_00223291; iTF_00223324; iTF_00222621; iTF_00222654; iTF_00226725; iTF_00226693; iTF_00230160; iTF_00230126; iTF_00676121; iTF_00676148; iTF_00391435; iTF_00391464; iTF_00633741; iTF_00633770; iTF_01454324; iTF_01454285; iTF_00141334; iTF_00142580; iTF_00142554; iTF_00141309; iTF_00087303; iTF_00087329; iTF_00085515; iTF_00085547; iTF_00088148; iTF_00088183; iTF_00088941; iTF_00088967; iTF_00140719; iTF_00140686; iTF_00086423; iTF_00086453; iTF_00084668; iTF_00084695; iTF_01123159; iTF_01123183; iTF_01255800; iTF_01255830; iTF_01424505; iTF_01424473; iTF_01539705; iTF_01539736; iTF_01169274; iTF_01169304; iTF_00118139; iTF_00118107; iTF_00625628; iTF_00625605; iTF_01071100; iTF_01071127; iTF_00393728; iTF_00393698;
90% Identity
iTF_00118139;
80% Identity
iTF_00306410;