Basic Information

Gene Symbol
-
Assembly
GCA_018883505.1
Location
RCIC01000004.1:8353212-8354448[+]

Transcription Factor Domain

TF Family
zf-GAGA
Domain
zf-GAGA domain
PFAM
PF09237
TF Group
Zinc-Coordinating Group
Description
Members of this family bind to a 5'-GAGAG-3' DNA consensus binding site, and contain a Cys2-His2 zinc finger core as well as an N-terminal extension containing two highly basic regions. The zinc finger core binds in the DNA major groove and recognises the first three GAG bases of the consensus in a manner similar to that seen in other classical zinc finger-DNA complexes. The second basic region forms a helix that interacts in the major groove recognising the last G of the consensus, while the first basic region wraps around the DNA in the minor groove and recognises the A in the fourth position of the consensus sequence [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 4 0.5 4.9e+03 -2.1 0.0 34 45 41 52 33 55 0.59
2 4 0.00041 4 7.8 0.1 21 43 56 78 39 83 0.83
3 4 0.0012 11 6.3 0.3 21 45 84 108 79 116 0.81
4 4 3.1e-07 0.0031 17.7 0.5 10 47 128 166 120 171 0.79

Sequence Information

Coding Sequence
ATGTCCGTGCAGCAAGAGAGGCCCCTGGACTTGAGCTGCAAAAGGAGGAAGGGGGAGGTAGACCGGAAGGGCCGGAAAAACCTCAAGTGCCTGCTACCCTGCCAAGTATGCGGGAAGAATTTCGACAGGCCGTCCTTGCTAAAAAGGCATTTGCGCACCCACACAGGGGAGAAACCGCACGGGTGCCCGATCTGCGGGAAAACCTTTAGCACGAGCAGTTCCCTCAATACGCACGCGAGAATCCACACGGGCGAGAGGCCACACGAGTGTCCCATGTGCGGTAAACGGTTCACCGCATCCTCCAACCTCTACTACCATCGAATGACTCATTACAAGGTGAAGCCGCATAAATGTACGGAGTGCGAGCGCTCCTTCCCCACGCCCGGGGACTTGCGAGCTCACGGCTACTCTCACTCGGGGAACTGGCCCCTGAGATGCCCGATCTGTTTCAGGGGCTTCTGCAAGCCAAGGATCTTACAGCGTCATTTGGAGCTTCACAATGGTGTCCGTAGAATTTTTAAGAAGAGATTCTCTGCAGCCAACACGTCCCGCACACTAAAACAACCGACCGACGATAAACGACTCGGCTCCCTAATCTTCCCTTGCATAACGAACGTCCCTGTCTCGTCCTTACCATGGATACTCTAA
Protein Sequence
MSVQQERPLDLSCKRRKGEVDRKGRKNLKCLLPCQVCGKNFDRPSLLKRHLRTHTGEKPHGCPICGKTFSTSSSLNTHARIHTGERPHECPMCGKRFTASSNLYYHRMTHYKVKPHKCTECERSFPTPGDLRAHGYSHSGNWPLRCPICFRGFCKPRILQRHLELHNGVRRIFKKRFSAANTSRTLKQPTDDKRLGSLIFPCITNVPVSSLPWIL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00305188;
90% Identity
iTF_00305188;
80% Identity
iTF_00305188;