Ccap001988.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Ceratitis capitata
Gene Symbol
gprs
Assembly
GCA_000347755.4
Location
NW:4220012-4242862[-]

Transcription Factor Domain

TF Family
BTB
Domain
zf-C2H2|ZBTB
PFAM
PF00651
TF Group
Zinc-Coordinating Group
Description
The BTB (for BR-C, ttk and bab) [6] or POZ (for Pox virus and Zinc finger) [1] domain is present near the N-terminus of a fraction of zinc finger (Pfam:PF00096) proteins and in proteins that contain the Pfam:PF01344 motif such as Kelch and a family of pox virus proteins. The BTB/POZ domain mediates homomeric dimerisation and in some instances heteromeric dimerisation [1]. The structure of the dimerised PLZF BTB/POZ domain has been solved and consists of a tightly intertwined homodimer. The central scaffolding of the protein is made up of a cluster of alpha-helices flanked by short beta-sheets at both the top and bottom of the molecule [2]. POZ domains from several zinc finger proteins have been shown to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes including N-CoR and SMRT [5, 3, 4]. The POZ or BTB domain is also known as BR-C/Ttk or ZiN.
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 2 6.2e-08 1.2e-05 24.9 0.0 9 45 38 79 31 102 0.83
2 2 5.2e-10 1e-07 31.6 0.0 48 106 127 184 112 187 0.89

Sequence Information

Coding Sequence
ATGCCCGAAGCTTTGACACTGCCCGGCATGGCTGATGCGGAGCCAGATTTGTCAACGTTCGAGAATAAGACCGGCTTGGCCGAGGATATGAAATTTCTGGCCTCAATGCCAGAATTATGTGATGTTACGTTTCTAGTTGGTGATACGCGCGAACCGGTTTGCGCGGTGAAGGCCGTTTTGGCATCACGCTCTCGCGTTTTCGCCAAAATGCTCTACTCGGCACCATCGCCGCAACGTAAACGAGAAGCATCGACTAAAGAGAATAAATTGCGGCTTTTTCTGAAACGCTCATCGGAGCCATTGTTGAATTTACAAAATGCGGCACAACAGAGAAGTGGTTTCACCCAACAATTAGCTCCGATACCTgagCCCGCTGGACAACAACATCAAACATTGATTATTGAGGAATTCGAACCGGATGTTTTCAGGCAACTGatagagtacatacatacagggtgTGTGACATTGCAGCCGCGGACACTTTTAGGTGTTATGAATGCAGCTGACTACTACGGCTTGGAGGAGTTGCGTCGCGCTTGCGCTGGCTTCGTACAGTGTTGCATCAACGTGGACACTGTCTGTGCGCTGCTGGCCTCTGCGGAGCGCTACATTCAATACAAATGCACAAAGAGTTTGGTACAAAAGGTGCTGGAATTTGTGGATGAGCATGGCAATGAGGTGCTCAATTTGGGCAGCTTTACGTTGTTGCCACAGCATGTAGTGCGTCTGATTTTGGCGCGTGAGGAGTTGCGTGCCGATGAGTTTACTAAGTTTCAGGCAGCGTTGATGTGGAGCAAGAAATATTTCGACAACAATCAGAATATCGATATGAAGGAGATTTTGGGCAACTTTCTGGAGTACATTCAATTTCATAAGATACCCGCGAATGTGCTGATGCGCGAGATACATCCGTTGGGTTTGGTGCCATATTCGATCATTATGAATGCTTTGGCTTATCAGGCAGACCCAGAAAGCATCGACCCCGGAAAGCTGTCTCCCAACTCTAGTCGCTCGCACGGCCGTCACAGGCATCATCAATCATTACCGAAAATTCGCAAAGCCAAATCTCAGAGTTTCCGCACCCGACGCAGCCCATCTGAGCGCCGCAGCCCAAATACCGCACCCATTTTCGGTCAAGCGGCCAACCTAACACTGAACACCGCCCAATTGGCGGCCAATGATAAGAAACGCAGTCCACTTACACCAAAGAGTCCCATACTACCACAATCGGAATCGAAAAGTCCCGGCAGTACTTCGCAGAAAACGCCTACAACACTATCCCGACAGGGCACGCTACGTGCATCGCATCGTCGCAAGAGCAGCATGACCGGTTCACTGGTGCTGGTGCAAGGTCGGCGCAGTCCCGTGGGCTTCAATGACCGCAGTCCGCAAGGACGCCGTAGCCCATTGATTATGTCAAGTGATCGCCTGAAGTCACCGAATGAATTGCCCGTACAGCCCATGTTTGGTTTGGGTATACATAGTCCAACAGCGCGTAGTCCTACGGGTGGTGCACGTAGTCCAACACTCAGCATGCACACACAGGAGCGGCGTTCACCCATCGGCGCTGCGGCACCAATAGAATTTGGACAACCGCGACGCAGTCCCACCTCCACCGTACATGTGCAGGGTGCACACTTTGGCGAGGGAGAGACGAATGAGAATGGCATGGTGCGATCCAGCAGCGGTATAAAGCGTCCATCAATCAATCTCTTCACACCCATCTACTTCAGCGGTGACAAGCGTAGTCCCATTACTGCGATGCCAATACCACCAATCACTGTTTCCAACCCCACGGAAACGGGTAGATTAGCTGAAAAGATTGCCGAGTCCAATGCGGCAGCAGAAGCAGCACAGGAACTTGAGCGGCAACGCGAAGAACAAGAAGCGGCTGCGGCCGCCGCAAAGGAGGCAACACCTGAGAAGAAGGAGCGTACGAGCGTGATGAAAGAAATACTCGCCTTTGTGCGTAAGCCGTCGAAGCATATATCAACGCGCACAAATCGTTTTGCAAATGCTTTTACACGCGCCGAGTCGGGCTCATCATCGGGACCGCTAATTAGACAGAGCACATTCTCGGCCAGTCCGGCCGCATCATCGACGGCGGCTAAAAGTGCGGTGGTAAAGCAAATGTCTGAAGTTGCATTCGAACCGAAGATGTCATTGAAATTCGCACACTACGCTAAAATGTCACTGAAACTACGTCGATCTGCCAACGACGATAAGGCGAAGCAAGCAGCTTCAGCGAGCACATCGAAACGTGCCAGTGCCGACTCAAACttcagcagcagcggcggcggtgGCTGCGGTTTGGATCCACACGATGCACAGGTAGGTCGCGCCGGTGGCAGTTTCGGCGGTGGTGCCGGCTCTGGACGTGCATCACCGCTCGGCGAACTGCCATTCGAGTTGGCGAATGTGCATTTCGAGAAGGTCGGTGAGTCGTATATTAAGCACGAGAAAATACACGAAGAGGAGTATGTAGATGAAGCCGGCACCACAACCGACACGATAGTCACCAGTTTGGTAGAGGAGATCACAAATTCGCTCAAAGTAGTCTCGTTGTCAAATGAGAACACACAAATCACACATCACTTTCAGCGACGCTCCGAAAGTCGTGAGCCCATTGAGCCGCGTATAAGCGAAGAACGGGAATCCGACTCGAATGATCTTGTAATTCCAGAGGATTTCCGTACTGAGCTAACCGAAATCATAAAAGCCTATCCACCAGAaccaatttatgtaaatttgcaaGTGTTACGCCGCGAAACTGAAGAGGCCGAGGCGGCTGCTGCACAAGCACTTGCCAAGGCTACCGAAACGAGTATTACGGCTGAAAAGTCGCCACTGCAATGTCCGATTATCGAGTTTGAACCGCCTTCACGGCGTTCCTCTTTCGATCCGCCACGTTCGCCATTTCTAGAGAATTTGCGTAGTCCCGGCGCTGACACCGACAATGATTTGATAAACTTGCAGCGCCTCGACTCGGGTGGTGATAGTTTTGAAATGGTTGAGGGCGATCGGAAATCAAGTCGCGCTGAATCTAGTTTCGATTGTCCCTATTCATCGCGTGATACTAGTTTTGACATCTCGCGTTATCAATCCACCAGCTATGAAGATCAAACTTCCAGCTTTGAGATTGTAGATATGGACGATAAGAAGAAATCGAATATTGACTTGCGCAAATCCTCCATCGAACTAGTCGATGCGGAGACCTTTCAACGTAGTGGCTATTCATGTGGACGCAAGTCTTCGCTGGAAACACACTTTGATTATACGCCCTCCGATGCGAGTGGCATGACACCGGCACGTTCGCCCAATTTCCCtgtaaataagaaacaaaaacccGAAACCCTACGTGCTCTACGCATTTCACCCTTCAGTGCCTTCTCGCGTGCACGTAGTCCACTCTCCAATCAGACTTCATCGAACTACAGTTCACGTGATAGTTACGACTCCAGCTCCTCCTATCCACATTCAGCTCCCAATCACCACGAACCGCAGCGCAGCCCCTTTGCCGATCcgacaaaaaaacattttccgcTCACTATCAAACAACGTGAGGAAGAGGTGAAAACCTTTCTCTGTACCGATCAACGTTGTGCTTCGATATTTGAGCCACGACCCAGTTCGGTGTTGACACAACAACTTTCAACTGGTTCAATGTCCACACCGTCAGGTTATGGCAATGGCACACCATGTCCAGTAGTCGGGGGTGGCGGTGTTGTGACTGCGGGTTTCTCAAGCGGTAGCGAGTTTGAGCCACCATCACCACGCCGAGCGGCGAGTGCTTCACCCAAACACACATTCACTTTTCGTATTgttatgaaaaaagttgataGTTCGCCGGAGGCTTTGTGTCCCGAACGACATCGCAGTCGCATATTCGATAGATATCGGCGTAGAGATAGTCGACGCAAGAGAATACATGAGGCGGGcaagagtttttaa
Protein Sequence
MPEALTLPGMADAEPDLSTFENKTGLAEDMKFLASMPELCDVTFLVGDTREPVCAVKAVLASRSRVFAKMLYSAPSPQRKREASTKENKLRLFLKRSSEPLLNLQNAAQQRSGFTQQLAPIPEPAGQQHQTLIIEEFEPDVFRQLIEYIHTGCVTLQPRTLLGVMNAADYYGLEELRRACAGFVQCCINVDTVCALLASAERYIQYKCTKSLVQKVLEFVDEHGNEVLNLGSFTLLPQHVVRLILAREELRADEFTKFQAALMWSKKYFDNNQNIDMKEILGNFLEYIQFHKIPANVLMREIHPLGLVPYSIIMNALAYQADPESIDPGKLSPNSSRSHGRHRHHQSLPKIRKAKSQSFRTRRSPSERRSPNTAPIFGQAANLTLNTAQLAANDKKRSPLTPKSPILPQSESKSPGSTSQKTPTTLSRQGTLRASHRRKSSMTGSLVLVQGRRSPVGFNDRSPQGRRSPLIMSSDRLKSPNELPVQPMFGLGIHSPTARSPTGGARSPTLSMHTQERRSPIGAAAPIEFGQPRRSPTSTVHVQGAHFGEGETNENGMVRSSSGIKRPSINLFTPIYFSGDKRSPITAMPIPPITVSNPTETGRLAEKIAESNAAAEAAQELERQREEQEAAAAAAKEATPEKKERTSVMKEILAFVRKPSKHISTRTNRFANAFTRAESGSSSGPLIRQSTFSASPAASSTAAKSAVVKQMSEVAFEPKMSLKFAHYAKMSLKLRRSANDDKAKQAASASTSKRASADSNFSSSGGGGCGLDPHDAQVGRAGGSFGGGAGSGRASPLGELPFELANVHFEKVGESYIKHEKIHEEEYVDEAGTTTDTIVTSLVEEITNSLKVVSLSNENTQITHHFQRRSESREPIEPRISEERESDSNDLVIPEDFRTELTEIIKAYPPEPIYVNLQVLRRETEEAEAAAAQALAKATETSITAEKSPLQCPIIEFEPPSRRSSFDPPRSPFLENLRSPGADTDNDLINLQRLDSGGDSFEMVEGDRKSSRAESSFDCPYSSRDTSFDISRYQSTSYEDQTSSFEIVDMDDKKKSNIDLRKSSIELVDAETFQRSGYSCGRKSSLETHFDYTPSDASGMTPARSPNFPVNKKQKPETLRALRISPFSAFSRARSPLSNQTSSNYSSRDSYDSSSSYPHSAPNHHEPQRSPFADPTKKHFPLTIKQREEEVKTFLCTDQRCASIFEPRPSSVLTQQLSTGSMSTPSGYGNGTPCPVVGGGGVVTAGFSSGSEFEPPSPRRAASASPKHTFTFRIVMKKVDSSPEALCPERHRSRIFDRYRRRDSRRKRIHEAGKSF

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00979463;
90% Identity
iTF_00091445; iTF_00193698; iTF_01563909; iTF_00192198; iTF_01563038; iTF_01045611; iTF_00191473; iTF_00082261; iTF_00083083; iTF_00190779; iTF_01189629;
80% Identity
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