Crub019842.1
Basic Information
- Insect
- Cerastis rubricosa
- Gene Symbol
- Litaf
- Assembly
- GCA_949152445.1
- Location
- OX424534.1:12126995-12127580[+]
Transcription Factor Domain
- TF Family
- zf-LITAF-like
- Domain
- zf-LITAF-like domain
- PFAM
- PF10601
- TF Group
- Zinc-Coordinating Group
- Description
- Members of this family display a conserved zinc ribbon structure [3] with the motif C-XX-C- separated from the more C-terminal HX-C(P)X-C-X4-G-R motif by a variable region of usually 25-30 (hydrophobic) residues. Although it belongs to one of the zinc finger's fold groups (zinc ribbon), this particular domain was first identified in LPS-induced tumour necrosis alpha factor (LITAF) which is produced in mammalian cells after being challenged with lipopolysaccharide (LPS)[2]. The hydrophobic region probably inserts into the membrane rather than traversing it. Such an insertion brings together the N- and C-terminal C-XX-C motifs to form a compact Zn2+-binding structure [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 1 3.6e-21 1.2e-17 65.1 14.1 2 69 80 151 79 152 0.88
Sequence Information
- Coding Sequence
- ATGGATATGAACAGTGGTGTGAATCCAGCTCAAAGTGATATAGGCAGAGCAGAGTTTCAAGGGGACAGGGAAGAAAAAGATTTATACCATAGAGAACCACCACCGTCTTACGACGCGACATACAATTATGCTCCTCCCGTACCGCCACAAGTGACTAATCCACCTATTACTCAGCAACCACCAGTTACTAATCAGCCAACAATTCGAAGTGTTATCGTACACCTACCGCTAAAGCATTCTCCGACGCTCTTCAACTGTCCTAAATGTGATGAAAGAATTGTAACTAATGTTACTTATTCTAGTACAAACAAAACTCACATGCTAGCTGGCTTTGTTTGTGGAATTTCTTGttggTGCTGTCTTTGTTGCTTGGCTGCAATACCTTACCTCACAAAAATATTCAAGGAGGCTCAGCACTACTGCCCAAACTGCAAGGCACATTTAGGTTCATATTCAAAGTTCTAA
- Protein Sequence
- MDMNSGVNPAQSDIGRAEFQGDREEKDLYHREPPPSYDATYNYAPPVPPQVTNPPITQQPPVTNQPTIRSVIVHLPLKHSPTLFNCPKCDERIVTNVTYSSTNKTHMLAGFVCGISCWCCLCCLAAIPYLTKIFKEAQHYCPNCKAHLGSYSKF
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00426028;
- 90% Identity
- iTF_00301773; iTF_01535508; iTF_01534469; iTF_01065231; iTF_01533617; iTF_01064306; iTF_00712532; iTF_00686012; iTF_01532701; iTF_01063423; iTF_01062432; iTF_00929250; iTF_00445784; iTF_00447839; iTF_00446790;
- 80% Identity
- -