Basic Information

Insect: Cephus pygmeus
Gene Symbol: Hr39
Assembly: GCA_036026175.1
Location: JAYRBY010000729.1:187642-191126[+]

Transcription Factor Domain

TF Family: SF-like
Domain: zf-C4|SF-like
PFAM: AnimalTFDB
TF Group: Zinc-Coordinating Group
Description: The ligand binding domain of nuclear receptor steroidogenic factor 1 (SF-1): SF-1, a member of the nuclear hormone receptor superfamily, is an essential regulator of endocrine development and function and is considered a master regulator of reproduction. Most nuclear receptors function as homodimer or heterodimers, however SF-1 binds to its target genes as a monomer, recognizing the variations of the DNA sequence motif, T/CCA AGGTCA. SF-1 functions cooperatively with other transcription factors to modulate gene expression. Phospholipids have been determined as potential ligands of SF-1. Like other members of the nuclear receptor (NR) superfamily of ligand-activated transcription factors, SF-1 has a central well conserved DNA binding domain (DBD), a variable N-terminal domain, a flexible hinge and a C-terminal ligand binding domain (LBD). [1, 8, 3, 11, 6, 5, 12, 10, 9, 2, 4, 7]
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 5 0.45 3.9e+03 -2.6 11.2 47 163 191 314 177 346 0.63

2 5 0.48 4.2e+03 -2.7 1.6 79 129 343 399 317 435 0.44

3 5 5.4e-08 0.00047 20.2 0.0 1 21 517 537 517 542 0.92

4 5 0.73 6.4e+03 -3.3 0.0 90 113 572 599 551 606 0.56

5 5 7.2e-70 6.3e-66 224.0 0.0 202 408 701 902 676 902 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	5	0.45	3.9e+03	-2.6	11.2	47	163	191	314	177	346	0.63
2	5	0.48	4.2e+03	-2.7	1.6	79	129	343	399	317	435	0.44
3	5	5.4e-08	0.00047	20.2	0.0	1	21	517	537	517	542	0.92
4	5	0.73	6.4e+03	-3.3	0.0	90	113	572	599	551	606	0.56
5	5	7.2e-70	6.3e-66	224.0	0.0	202	408	701	902	676	902	0.95

Sequence Information

Coding Sequence: ATGTCGGAGCAAAACGGGCCCACGGAGGGCCCGGGCCCGGGCTGGTGGCCTCCGGCACAGTCCTGGAAGTCATCTTCGTTGGGCGCACGCACCGAGGCTGGGAAGAACGTTTCCGTCACTACGATTAACGTACCGCCCGCCCATGAGATGCATGACGGTAAGAGCGTCTGCAAGTATCTGGGAGGACAGAATGGCGTGACGGTTTCAGTGGTGTCCAGCTGCGGATCAGCTTCCGCTTCTGGGTCCAGTAATGTCGTCGGTACCGGAAACGCTGGCGAGTCCGGTTCCGTGGACGACGTTGAAGACAGTGACGGTGAGGTGAGCAAGATCGACTTCCGGGGTGTTAATCTGCGCACGAAGAAGAAACGGGATGCTTCCGGCGGACAAGAAAGTGAGAACAGTGCAATTGGCACTGACAATATTCAGCAGCAACCCGAAAGGCCAATGTCTTGGGAGGGTGAACTCTCGGACCAAGAAATGTCTTCCAATACTATCACGAACCAGGACCACGAAGAAACGTTTATGGAGGGTGTACAAGTGTGCAGTGCGAGTCCTGGACCACAGGAACAAAAGTTTCCAATAAAACCGGAGCCGGACTTTAGGTCAAGTCCAGGACTCGCTTTGGGCTCCCACAATGAGACGGCCTTGCCGCTTACTCATGCTCAGcaactgcagcagcagcaacagcaacaacagcaacagcagcagcaacaacgtGGTCTGGACGGTCTTGAGCAGACACAGCAGAGCGACTTACCCTTGCTGGTTGGCAAACTCCTAGGGGGTTATAATAGTTCAACCCCGAATCACAGTCCTGTACTAAATCCCCGGCATCATCTTACTAAGCACAGTCACACCCGGTCTCAAGTCCCTTCGCCGGATTCGGCGATTCACTCGGCCTATAGTGTCTTTAGCTCTCCCACGCAGAGTCCTCACGCGGCACGGCACTCTGCACTAGGGGCTGGCAGTCCTGTACCATCCTCATCGCTGTCACTTTCACGACACAGTTTCAATAATTCCACGTCTTCGTTATccttgtctctctcgcactctctaTCGAGGAACAATTCGGACGCCTCCAGTAGCTGCTACAGCTACGGATCCCTTAGTCCGCCGACACACTCGCCCGTCCAGCAACCGAGGCATTCCCAtccgcagcagcagcatcatcAAGTCACTCAGGGCAGTCCTTTGCATCTACCCGCAGCCACCGGTGCCACTCATCATTATTCCACCCCGGGATCGGAACTCTCGGAGGGTCTCGCAGAGGACCAAGAAGACTGTAGGATAGCGCCGGCACCCTCGGGCATCTCCACAAGGCAGCAACTTATAAATAGTCCATGTCCAATATGCGGCGACAAGATCAGCGGCTTCCATTATGGTATATTCTCCTGCGAATCCTGTAAGGGATTCTTCAAGAGGACCGTACAGAATCGTAAGAATTATGTGTGCCTACGTGGCGCGGGATGCCCCGTCACTGTCGCCACTAGGAAGAAGTGTCCGGCATGCCGATTCGACAAGTGCCTGAATATGGGGATGAAGCTGGAAGCGATAAGGGAGGATAGGACTAGAGGCGGTCGCAGTACCTATCAGTGTACCTATACTCTACCTGCTAACCTTATCGGTGGGTCTGCTGGTGGCATTTCCGGTGATAAAATCACCGGTGGTACCTGCAGTCCAGCACCGCCGGGATCGGAGCATCATCACTCAATGAGACATCATTCAAATCATTCGCACAAGCTGCAAATGGTGCCACAGCTCCTACAGGACATCATGGACGTGGAGCATCTCTGGCATTACAACGACAATGATCGTATGACTAGTGGCCAGGGTAGTGGTATCAGTGGTGGTAACGGTAGTGGTAGCGctggcggtggcggtggtggtggtagcgGTAGCGTTAGTGGTGTCAGTGGTAGTGCTAGTGGCGGTGGAAATTCATCCGGAGGCGGAAGTTCATCCGCCCTCGGAAGTAACGGGAACATACCTGGAGGAGAGTCGTCGAGACCAAGTTCCGCGGGTCCTCCATCCTCCAATCACGAACAACATTCACCACCGGCGAGTACCCCTAACTCGAATTCAACCTCCAATCCTAATGGGAATCCCACGCAGCATCCGGACTTTCTTTCAAATCTGTGTAACATCGCCGATCATAGACTCTACAAGATCGTCAAGTGGTGCAAGAGTCTACCGCTCTTCAAGAACATCTCCATAGACGATCAGATATGCCTTCTTATCAACTCCTGGTGCGAACTCCTCTTATTCTCCTGTTGCTTTCGCAGTATGAGTACGCCTGGCGAGATCAGGGTGTCCCTTGGCAAGTCGATTACTCTCGAACAGGCGAGACAGCTAGGTCTTGCGACGTGTATCGAGAGGATGCTGGCCTTCACAAATAATCTTAGACGACTCAGGGTGGATCAGTACGAGTACGTGGCGATGAAGGTCATAGTTTTGCTAACCTCGGACACCAGTGAACTGAAAGAACCCGAGAAGGTAAGAGCGTCCCAGGAGAAGGCTCTTCAGGCACTGCAGCAGTATACAATCGCAAGGTATCCGGAGATGCCGGCAAAGTTTGGAGAGCTGCTACTCAGGATCCCGGACCTGCAGAGGACTTGTCAGGCCGGGAAGGAGTTGCTCAGCGCAAAGCGTGCCGAGGGCGAAGGCAGCTCTTTCAATCTACTGATGGAACTTCTACGAGGCGATCATTGA
Protein Sequence: MSEQNGPTEGPGPGWWPPAQSWKSSSLGARTEAGKNVSVTTINVPPAHEMHDGKSVCKYLGGQNGVTVSVVSSCGSASASGSSNVVGTGNAGESGSVDDVEDSDGEVSKIDFRGVNLRTKKKRDASGGQESENSAIGTDNIQQQPERPMSWEGELSDQEMSSNTITNQDHEETFMEGVQVCSASPGPQEQKFPIKPEPDFRSSPGLALGSHNETALPLTHAQQLQQQQQQQQQQQQQQRGLDGLEQTQQSDLPLLVGKLLGGYNSSTPNHSPVLNPRHHLTKHSHTRSQVPSPDSAIHSAYSVFSSPTQSPHAARHSALGAGSPVPSSSLSLSRHSFNNSTSSLSLSLSHSLSRNNSDASSSCYSYGSLSPPTHSPVQQPRHSHPQQQHHQVTQGSPLHLPAATGATHHYSTPGSELSEGLAEDQEDCRIAPAPSGISTRQQLINSPCPICGDKISGFHYGIFSCESCKGFFKRTVQNRKNYVCLRGAGCPVTVATRKKCPACRFDKCLNMGMKLEAIREDRTRGGRSTYQCTYTLPANLIGGSAGGISGDKITGGTCSPAPPGSEHHHSMRHHSNHSHKLQMVPQLLQDIMDVEHLWHYNDNDRMTSGQGSGISGGNGSGSAGGGGGGGSGSVSGVSGSASGGGNSSGGGSSSALGSNGNIPGGESSRPSSAGPPSSNHEQHSPPASTPNSNSTSNPNGNPTQHPDFLSNLCNIADHRLYKIVKWCKSLPLFKNISIDDQICLLINSWCELLLFSCCFRSMSTPGEIRVSLGKSITLEQARQLGLATCIERMLAFTNNLRRLRVDQYEYVAMKVIVLLTSDTSELKEPEKVRASQEKALQALQQYTIARYPEMPAKFGELLLRIPDLQRTCQAGKELLSAKRAEGEGSSFNLLMELLRGDH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00676835;
90% Identity: iTF_00770401;
80% Identity: iTF_00294567;