Basic Information

Insect: Cephus cinctus
Gene Symbol: ush
Assembly: GCA_000341935.1
Location: NW:70338-103272[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 8 0.0041 0.25 11.2 0.0 3 20 266 283 264 285 0.92

2 8 0.00058 0.035 13.9 2.0 1 23 316 338 316 338 0.98

3 8 0.07 4.2 7.3 1.6 3 20 372 389 371 391 0.93

4 8 0.01 0.63 9.9 4.4 2 21 594 613 593 614 0.94

5 8 0.049 2.9 7.8 0.0 3 20 641 658 639 660 0.91

6 8 0.072 4.3 7.3 0.0 2 23 699 720 698 720 0.94

7 8 0.0064 0.39 10.6 1.4 1 23 726 748 726 748 0.99

8 8 0.068 4.1 7.4 0.5 3 21 837 855 836 856 0.92

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	8	0.0041	0.25	11.2	0.0	3	20	266	283	264	285	0.92
2	8	0.00058	0.035	13.9	2.0	1	23	316	338	316	338	0.98
3	8	0.07	4.2	7.3	1.6	3	20	372	389	371	391	0.93
4	8	0.01	0.63	9.9	4.4	2	21	594	613	593	614	0.94
5	8	0.049	2.9	7.8	0.0	3	20	641	658	639	660	0.91
6	8	0.072	4.3	7.3	0.0	2	23	699	720	698	720	0.94
7	8	0.0064	0.39	10.6	1.4	1	23	726	748	726	748	0.99
8	8	0.068	4.1	7.4	0.5	3	21	837	855	836	856	0.92

Sequence Information

Coding Sequence: ATGAGTGTCCTGCTTTGGCGACAACGTAGAGCCAGTCTACGATCTACGATAACCGCGATTTCTGGATCGAGGGAGGATGAAGAGTGGAGCGACTCGGAGAAGACTCCGTCTGTGAGCAGCGGGATAGAGGGTGGCGGATCAGCAGTATCGAGCCCTGCGGCACCACCTGTTGAGGAGGAACCGAATCTTCCGCCACCTCCAAGACTTAATCCTTCCGGTACTGGCTTACCACCGACTTCCGCCGCAGAGGACTTCCGGTTGCGACTCAGCGTCCTCTCCGAGGACACTCGTAAGCGGTTAGTCAGCCTTACTGAGGATATCGAGGCCGCTAGAGGATTACGAGAACGTCATGCCTCCTCGAGGTCGACGCAGGGTCGCGAACCAAGTCCCAAGAAGCCCCAATCAGACCCCGACGAGGATGGCAACGTTCCTAAGGATGAGGACACATCAAGACCTTCGTCCTCGATATCATCGTCGCGAAGGAGGGAGGCGAGGAGGGACTCCGAAGACTCGAGACGCTCCGACGAGCCTCCAATAGACTCTAAGAGGACGAAACTCGACGACGATGCTGCCCCGAGACTGAGACTGAATGCTAGTCTGGCAACGGACCCTGCACTCCGGCCAGCTACCGTTGCCGCCCTTACTATCAAGCCTGAGAACATCTCCCCTCCGAATCCCGCAGCACCACTTTCTGCAGGACTTCAAAATGCTATTGCATCAGGTCGCTTATTCGTTCTGCCAACCGACGGGAAGGAAACGATAACCGTGGAACCAGCAAGACCAGCTCCTCTCATCTGTCCACCTTGTGGTATACGATTTAGTTCCGCAAGCACCCTGGAAGCTCACCGGACCTTCTACTGTGCGCACAGACCTCGCGTCGATGAGGAACCGAcgaacgacgacgacgaggagaaGACTGGTGGAAAGTTTGAAGTCCGCAAGGCTTACGCCTGTCCGCACTGTTCCTATAGCAACGACAAGAAGGTTTCCTTGAATCGGCACATGAGGATGCACGCGTCGTCGCCGGTACCGCCACCTGTGCCGGCAGCACCTTTAACTCCCGGTACCGGAAATGCTGCTAACGGTTCGTTGAATGAGGAGGCTGAGAGATACTGTCGCAATTGCGACATCAGATTCAGCTCCTTAAAAACGTATCGCGCTCACAAAACGCACTACTGCAGTACCAGGCATGTTGTCAAGGACGTTCCTCCTCCGGTTAAGGCCTCACCACCGACGAGTTCGAGTCCTGGGGACTCGCCACCACCTCAGCCATGTCTAGCGCTTCCGACAAATCCTATCCTGATTGTTCCCTATTCCTTGTTCCGAGGCGCGAGCGTGCTGGCTGCTCCTGCTCTTCCTGCTCCCGATACAGCGTGCTTCCTTCTACCAAACGGGTCCCTACAGCCGATGACGAGGACTCTGTCTGCGCCACAAACCACCACCGAGGCTCCGGCTGTCCTCAGGGCAGCCAACAAGCCTTCCACGCCTGCATCTGTCGTCGCTGCTACGTCGCCATCCTCAGCAACGGCTCCTCTAGATCTCAGTGTTAGACGATCGCCAGTTCTACAGGATGAAAAGGAGAATAGAGTCTCGCCGGCACCGTCCTTACCTCCGCCAGGAAGTCCTAGGTCTCGTGGTAGTAGCAGTCCAAGGACACGATCGTTACCAACTGCACAGACTGGTTCTGCACCTGCCCCGCCACCCACAGAGTTGGCATTAAGATTGGCTGAACTGCCACCACCTCCCGTTCCTAGTGTTCTCGTCAAGCAGGGTGTATCCAGATGCAAAGAGTGCAATATAGTCTTCTGTCGGCATGAGAATTTCGTGGCGCATAAAAAGCATTACTGCCAAGCAAGGGAAAGTACTGTCAGTAGTCCACCTCCACCTGGAACTCCTTCACCGCCGTTGGTGCAGCTAATTTGTGCCGCTTGCGGTATTAAATTTGCCTCGATGGACAACTTAGTGGCACATCAAGCCTTCTACTGCCCCAAGAAGCCCGAACCAAAGGAACATCATTCACGTTGTCGCAAGTGCAAGGTCGTAATCGAACCGGGCACAACCCACACATGTTCGAGTGGACCAACAGGAGGCTGGATATGTCCAGTATGCGGGGCCATAAGTCCCACAGCTGGCGCAGCCCAGCGTCATATGGACGCTCATCAAGGTGTCAAGGCGTTCCGATGTACAATTTGTCGGTACAAGGGTAACACTCTGAGGGGTATGAGGACGCACATCAGGATGCACTTTGAAAAACGTGGCACGGATCTTCAGGAGGAAAACTATATAATCTGTGTTCTCGAAGACGACACAACTGTTCCGACGTCGGAACCAGCGCCTGCAACCACACCGGAAGAGATCCCAGCGGAGGCTCAGGTCAATGGTAAAACGGAAGTGCGAAAGAGTCCTCAGCCGCCGGCAACTTCCGTACCGAGCAAAGTGAAGCAGGAACGCGAAGACACCCCACCACCGGAAGAAAGTCTGGATCCCAGTAAAACTGGGCCGCGTTACTGTCGCTCCTGCGACATAAGCTTCAATTACCTGAGCACTTTCATAGCCcacaagaaattttattgctcGAGCCACGCCGGCGAAGtgagcaacaacaacaacaacaacaacaactcGAGTAGCCACGCGACAACACCACCCAGTAGCAGGACTGAAGCATCTGTACTTTAG
Protein Sequence: MSVLLWRQRRASLRSTITAISGSREDEEWSDSEKTPSVSSGIEGGGSAVSSPAAPPVEEEPNLPPPPRLNPSGTGLPPTSAAEDFRLRLSVLSEDTRKRLVSLTEDIEAARGLRERHASSRSTQGREPSPKKPQSDPDEDGNVPKDEDTSRPSSSISSSRRREARRDSEDSRRSDEPPIDSKRTKLDDDAAPRLRLNASLATDPALRPATVAALTIKPENISPPNPAAPLSAGLQNAIASGRLFVLPTDGKETITVEPARPAPLICPPCGIRFSSASTLEAHRTFYCAHRPRVDEEPTNDDDEEKTGGKFEVRKAYACPHCSYSNDKKVSLNRHMRMHASSPVPPPVPAAPLTPGTGNAANGSLNEEAERYCRNCDIRFSSLKTYRAHKTHYCSTRHVVKDVPPPVKASPPTSSSPGDSPPPQPCLALPTNPILIVPYSLFRGASVLAAPALPAPDTACFLLPNGSLQPMTRTLSAPQTTTEAPAVLRAANKPSTPASVVAATSPSSATAPLDLSVRRSPVLQDEKENRVSPAPSLPPPGSPRSRGSSSPRTRSLPTAQTGSAPAPPPTELALRLAELPPPPVPSVLVKQGVSRCKECNIVFCRHENFVAHKKHYCQARESTVSSPPPPGTPSPPLVQLICAACGIKFASMDNLVAHQAFYCPKKPEPKEHHSRCRKCKVVIEPGTTHTCSSGPTGGWICPVCGAISPTAGAAQRHMDAHQGVKAFRCTICRYKGNTLRGMRTHIRMHFEKRGTDLQEENYIICVLEDDTTVPTSEPAPATTPEEIPAEAQVNGKTEVRKSPQPPATSVPSKVKQEREDTPPPEESLDPSKTGPRYCRSCDISFNYLSTFIAHKKFYCSSHAGEVSNNNNNNNNSSSHATTPPSSRTEASVL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00294805;
90% Identity: iTF_01475760;
80% Identity: -