Basic Information

Insect: Cephus cinctus
Gene Symbol: Hr39
Assembly: GCA_000341935.1
Location: NW:179935-194263[+]

Transcription Factor Domain

TF Family: SF-like
Domain: zf-C4|SF-like
PFAM: AnimalTFDB
TF Group: Zinc-Coordinating Group
Description: The ligand binding domain of nuclear receptor steroidogenic factor 1 (SF-1): SF-1, a member of the nuclear hormone receptor superfamily, is an essential regulator of endocrine development and function and is considered a master regulator of reproduction. Most nuclear receptors function as homodimer or heterodimers, however SF-1 binds to its target genes as a monomer, recognizing the variations of the DNA sequence motif, T/CCA AGGTCA. SF-1 functions cooperatively with other transcription factors to modulate gene expression. Phospholipids have been determined as potential ligands of SF-1. Like other members of the nuclear receptor (NR) superfamily of ligand-activated transcription factors, SF-1 has a central well conserved DNA binding domain (DBD), a variable N-terminal domain, a flexible hinge and a C-terminal ligand binding domain (LBD). [1, 8, 3, 11, 6, 5, 12, 10, 9, 2, 4, 7]
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 5 0.7 3.8e+03 -3.8 12.5 52 164 196 318 177 363 0.58

2 5 0.35 1.9e+03 -2.8 1.7 79 129 343 399 313 431 0.43

3 5 3.7e-08 0.0002 20.2 0.0 1 21 517 537 517 541 0.92

4 5 0.56 3e+03 -3.5 0.0 89 113 575 599 556 606 0.53

5 5 4.8e-70 2.6e-66 224.0 0.0 202 408 701 902 676 902 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	5	0.7	3.8e+03	-3.8	12.5	52	164	196	318	177	363	0.58
2	5	0.35	1.9e+03	-2.8	1.7	79	129	343	399	313	431	0.43
3	5	3.7e-08	0.0002	20.2	0.0	1	21	517	537	517	541	0.92
4	5	0.56	3e+03	-3.5	0.0	89	113	575	599	556	606	0.53
5	5	4.8e-70	2.6e-66	224.0	0.0	202	408	701	902	676	902	0.95

Sequence Information

Coding Sequence: ATGTCGGAGCAAAACGGGCCCACGGAGGGCCCGGGCCCGGGCTGGTGGCCTCCGGCACAGTCCTGGAAGTCATCTTCGTTGGGCGCACGCACCGAGGCTGGGAAGAACGTTTCCGTCACTACGATTAACGTACCGCCGGCCCATGAGATGCATGACGGTAAGAGCGTCTGCAAGTATCTGGGTGGACAGAATGGCGTGACGGTTTCAGTGGTGTCCAGCTGCGGATCAGCTTCCGCTTCTGGGTCCAGTAATGTCGTCGGTACCGGAAACGCTGGCGAGTCCGGTTCCGTGGACGACGTTGAAGACAGTGACGGTGAGGTGAGCAAGATCGACTTCCGGGGTGTTAATCTGCGCACGAAGAAGAAACGGGATGCTTCCGGCGGACAAGAAAGTGAGAACAGTGCAATTGGCACTGACAATATTCAGCAGCAACCCGAAAGGCCAATGTCTTGGGAGGGTGAACTCTCGGACCAAGAAATGTCTTCCAATACTATCACGAACCAGGACCACGAAGAAACGTTTATGGAGGGTGTACAAGTGTGCAGTGCGAGTCCTGGACCACAGGAACAAAAGTTTCCAATAAAACCGGAGCCGGACTTTAGGTCAAGTCCAGGACTCGCTTTGGGCTCCCATAATGAGACGGCCTTGCCGCTTAATCATGCTCAGCAactgcagcagcagcaacagcaacaacagcaacagcagcagcaacaacgtGGTCTGGACGGTCTTGAACAGACACAGCAGAGCGACCTACCCTTGCTGGTTGGCAAACTCCTAGGGGGTTATAATAGTTCAACCCCGAATCACAGTCCTGTACTAAATCCTCGGCATCATCTTACTAAGCACAGTCACACCCGGTCTCAAGTCCCTTCGCCGGATTCGGCGATTCACTCGGCCTATAGTGTCTTTAGCTCTCCCACGCAGAGTCCTCACGCGGCACGGCACTCTGCACTAGGTGCTGGCAGTCCTGTACCATCCTCATCGCTGTCACTTTCACGACACAGTTTCAATAATTCCACGTCTTCGTTATCCTTGTCTCTGTCGCACTCTCTATCGAGGAACAATTCGGACGCCTCCAGTAGCTGCTACAGCTACGGATCCCTTAGTCCGCCGACACACTCGCCCGTCCAGCAACCGAGGCATTCCCAtccgcagcagcagcatcatcAAGTCACTCAGGGCAGTCCTTTGCATCTACCCGCAGCCACCGGTGCCACTCATCATTATTCCACCCCGGGATCGGAACTCTCGGAGGGTCTCGCAGAGGACCAAGAAGACTGTAGGATAGCGCCGGCACCCTCGGGCATCTCCACAAGGCAGCAACTTATAAATAGTCCATGTCCTATATGCGGCGACAAGATCAGCGGCTTCCATTATGGTATATTCTCCTGCGAATCCTGTAAGGGATTCTTCAAGAGGACCGTACAGAATCGTAAGAATTATGTGTGCCTACGTGGCGCGGGATGCCCCGTCACCGTCGCCACTAGGAAGAAGTGTCCAGCATGCCGATTCGACAAGTGCCTGAACATGGGAATGAAGCTGGAAGCGATAAGGGAGGATAGGACTAGAGGCGGTCGCAGTACCTATCAGTGTACCTATACTCTACCTGCTAACCTTATCGGCGGGCCTGCTGGTGGCATTTCCGGTGATAAAATCACCGGTGGTACCTGCAGTCCAGCACCGCCGGGATCGGAGCATCATCACTCAATGAGACATCATTCAAATCATTCGCACAAGCTGCAAATGGTGCCACAGCTCCTACAGGACATCATGGACGTGGAGCATCTCTGGCATTACAACGACAATGATCGTATGACTAGTGGGCAGGGTAGTGGTATCAGTGGTGGTAACGGTAGTGGTAGCGCtggcggtggcggtggtggtggtagcgGTAGCGTTAGTGGTGTCAGTGGTAGTGCTAGTGGCGGTGGAAATTCATCCGGAGGCGGAAGTTCATCCGCCGTCGGAAGTAACGGGAACATACCTGGAGGAGAATCGTCGAGACCAAGTTCCGCGGGTCCTCCATCCTCTAATCACGAACAACATTCACCACCGGCGAGTACCCCTAACTCGAATTCAACCTCCAATCCTAATGGGAATCCCACGCAGCATCCGGACTTTCTTTCAAATCTGTGTAACATCGCCGATCATAGACTCTACAAGATCGTCAAGTGGTGCAAGAGTCTACCGCTCTTCAAGAACATCTCCATAGACGATCAGATATGCCTTCTCATCAACTCCTGGTGCGAACTCCTCTTATTCTCCTGCTGCTTTCGCAGTATGAGTACGCCTGGCGAGATCAGGGTGTCCCTTGGCAAGTCGATAACTCTCGAACAGGCGAGACAGCTAGGTCTTGCGACGTGTATCGAGAGGATGCTGGCCTTCACAAATAATCTTAGACGACTCAGGGTGGATCAGTACGAGTACGTGGCGATGAAGGTCATAGTTTTGCTAACCTCGGACACCAGTGAACTCAAAGAACCCGAGAAGGTAAGAGCGTCCCAGGAGAAGGCTCTTCAGGCGCTGCAGCAGTATACAATCGCAAGGTATCCCGAGATGCCGGCAAAGTTTGGAGAGCTGCTACTCAGGATCCCGGACCTGCAGAGGACCTGTCAGGCCGGGAAGGAGTTGCTCAGCGCAAAGCGTGCCGAGGGCGAAGGCAGCTCTTTCAATCTACTAATGGAACTTCTACGAGGCGATCATTGA
Protein Sequence: MSEQNGPTEGPGPGWWPPAQSWKSSSLGARTEAGKNVSVTTINVPPAHEMHDGKSVCKYLGGQNGVTVSVVSSCGSASASGSSNVVGTGNAGESGSVDDVEDSDGEVSKIDFRGVNLRTKKKRDASGGQESENSAIGTDNIQQQPERPMSWEGELSDQEMSSNTITNQDHEETFMEGVQVCSASPGPQEQKFPIKPEPDFRSSPGLALGSHNETALPLNHAQQLQQQQQQQQQQQQQQRGLDGLEQTQQSDLPLLVGKLLGGYNSSTPNHSPVLNPRHHLTKHSHTRSQVPSPDSAIHSAYSVFSSPTQSPHAARHSALGAGSPVPSSSLSLSRHSFNNSTSSLSLSLSHSLSRNNSDASSSCYSYGSLSPPTHSPVQQPRHSHPQQQHHQVTQGSPLHLPAATGATHHYSTPGSELSEGLAEDQEDCRIAPAPSGISTRQQLINSPCPICGDKISGFHYGIFSCESCKGFFKRTVQNRKNYVCLRGAGCPVTVATRKKCPACRFDKCLNMGMKLEAIREDRTRGGRSTYQCTYTLPANLIGGPAGGISGDKITGGTCSPAPPGSEHHHSMRHHSNHSHKLQMVPQLLQDIMDVEHLWHYNDNDRMTSGQGSGISGGNGSGSAGGGGGGGSGSVSGVSGSASGGGNSSGGGSSSAVGSNGNIPGGESSRPSSAGPPSSNHEQHSPPASTPNSNSTSNPNGNPTQHPDFLSNLCNIADHRLYKIVKWCKSLPLFKNISIDDQICLLINSWCELLLFSCCFRSMSTPGEIRVSLGKSITLEQARQLGLATCIERMLAFTNNLRRLRVDQYEYVAMKVIVLLTSDTSELKEPEKVRASQEKALQALQQYTIARYPEMPAKFGELLLRIPDLQRTCQAGKELLSAKRAEGEGSSFNLLMELLRGDH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00059522;
90% Identity: iTF_00770401;
80% Identity: iTF_00292295;