Basic Information

Insect: Cephus brachycercus
Gene Symbol: egg
Assembly: GCA_030142315.1
Location: JARQSX010000444.1:527951-532571[-]

Transcription Factor Domain

TF Family: MBD
Domain: MBD domain
PFAM: PF01429
TF Group: Unclassified Structure
Description: The Methyl-CpG binding domain (MBD) binds to DNA that contains one or more symmetrically methylated CpGs [2]. DNA methylation in animals is associated with alterations in chromatin structure and silencing of gene expression. MBD has negligible non-specific affinity for DNA. In vitro foot-printing with MeCP2 showed the MBD can protect a 12 nucleotide region surrounding a methyl CpG pair [2]. MBDs are found in several Methyl-CpG binding proteins and also DNA demethylase [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 1 1.2e-13 4.7e-10 39.1 0.0 5 71 633 693 630 698 0.88

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	1	1.2e-13	4.7e-10	39.1	0.0	5	71	633	693	630	698	0.88

Sequence Information

Coding Sequence: ATGGCAGAATTAAAAGGTACTGAGGTGATTGAGCTAGACTCAGACGAAGGAGACATAcaaataagaaatgaaaatctgaaaagaaaagacactACACCGTGTCATGGAActtgtattaattttgtttgtaCTTCTggtttaaatatgaaaatcgcACCTAGCTTTGCTTGTGCTTATTATGGAGTTAATagatgtaagaaaaaaaaacgcttaatatgtgaaaaatgttttgaagATTCTATTACTCATCAGcagcAACTTGTGTCAGCACTGATAGCTAAAAAGCCATTGTTAGAGTGTGATTTTCCTGATCATACTATGGAAGTTGAAATCTCTGATAGTGATGATTCTGATGATGAAAGAAGTAAACTAATGGAACAAGAAGataattatttacctgAGAATGTATTATCtgacataaaagaaaaaattgatgatGCTTTATTATCTATCTTTAATAAGTATGACATTCAACATCAAATAGAAGAatctcataaaatattaaaagaacgATGGGAAAAAATTGATGcaAACACTGTGGAACTAAACAAAGACATTCAAAAGATGATGAGTGATGCGGATTCTTTGCGTGATAGATTCTATGAGGATTTTAAACCACAAATTCAATGGCTCAAGGAACTGCACATTGATGATAAACCGCTAGAGAACCATCTCTATCCACTAGTTGCTACCAAGAAGGTCACTCAAGTACGAGTGTCTCCGAATGCAGGACAATCCGATACACAACCAGAAATTATGCCATTGGAGCGTGTTGACAACAAACTAGAACCAGCAGACATTCCACCTCTTGGTCCTCTGATAAAACCGATACCAGACGTAGACAGCATCGTTTATGTTATGAAAAATCCTCTCATGCCGTGGGTCAAAGGAAAGGTACAAAGTATTATATCCAAAACACCAGTACACTGCCGAGTGAAATTACTTTCAAAGAGATACAACTCCATGGTCAAGTCTGTATATGGCAAGCAATTAGCAGTAGATGTTCTATGCCCAGTTGTTGTACCAGTTGGAACTCGTGTAGTCGCAATTTTTCATGACATTACTGGAAGTGACTATCATAGTGGGGTTATTGCCGAACCACCAAAGTCTATAAacaaatataggtatttaatattttttgatgaCGGATATGCACAGTACGTTactcacaaaaatatttttatcgtggCAGAAGCCTCACCGCGAGTTTGGGAAGATATCCCTACAGATTctcgtgaatttattaaaaagtatatggaATCTTATCCCGAGAGACCAATGGTCAAATTACAGACTGGTCAAATAGTGAAAACAGAATGGAATGGAAAGTGGTGGGTCGCACGAGTGAATCAACTCGATGCAAGTTTAGTTCAAATGCATTTCGATGCCGATGGAAGGACCGAATGGATATATAGAGGATCGGCTAGACTAGGTCCTCTTTTCATGGAGTTACTAAAAGCTAATGCCAGACAACATGGTTATCATGCCGTCAACACTCCTAGCCGTCATTGTCTTCCAGCCACAACTAATaaaaataatttaccataTGTTGAATATACTTCCTTTAATCCTGAATTGGATGACGAATTAGCGCCAGTCTCAAAATCTGATGTGCTTCTGAAAACTTTGTTGAATACAAGTGCAACAACAACGACTCGCAGTGTGCCCATTACTTCTGTACCTCAACAATCTCGTGCAGTTGCCAAAAAGAGTACAACCAAAAGACCACCTATCAGTAACACAACAATCCAAAACTCTGCAGAAATTAAGCCATCGCATAGTATTGTCtattatCAACCggaaaacaaaatcaaaacgaAAAAGTACATCCCACACAAATGTGGGCACGAATGTGTCGCAGGAATATCGTTTACACCGGATGATCTTCGAGGATATTCTCCCCTCTCAATTCCACTTCTCTGTGGATGGAATCGGCAGATTTCCAAGTTTCATAAGGGCAGAAAAGTGATCCTCTATCAAGCACCATGTGGTGTGAGACTTCGTAACATGGAAGAAGTACATCAATATTTACGTATTACTGGAAGTCCTATGTCAGTGGACCTGTTTGATTTTGATCATTGGGTTAATTGTTTAGCTGAATTTTCTTTGGACAAATGCTTTGTGAAGATAAACGATCTGAGCTATGGAGTTGAAAATGTGCCAATACCCTGTGTCAATGAACTTGACCATGCGCTACCAGATACAATCAGATATAGTACACGAAGAGAACCAACAGAAGGTGTCAACCTCAATTTAGATCCTGAATTTTTATGTTGCTGTGATTGTGAAGATGACTGTCAGgaTAAATCAAAATGTCAGTGTTGGCAACTGACAATACAAGGTGCGACTTTAGGCGGACGAGTGCTCAATACAGCTGTCGGATATGTATACAAGAGATTACCCGAACCGGTAATTACAGGAATCTACGAATGTAATAGCCGatgtaaatgtaatattaagaCTTGCCTCAATAGAGTGGTGCAGCATCCTCTTACTTTAAAATTACAAGTTTTTAAAACAGCACCCAGAGGGTGGGGAATAAGGTGCCTTAATGACATTCCGCTTGGctcatttatttgtatttatgcTGGAAGATTACTTACTGAACAAAGCGCTAacgagggaggaaaaaattatGGCGATGAATATCTTGCAGAATTGGATTATGTAGAAGGAGTAGAAGGTATTAAAGAAGGTTATGAAAGCGACGTTCTGGAACCAGAAGAAGTGGAAACAAACACTACCGACGatgagaaaaaatcaaaaactgCAGAAGCCAAACGTGGTTCATATGAATCAGATGAAGATTTTAATGTTGATATACCCGTGAACGTTAACGAAGCAGAAACTGCGTCTATCAGAAAACGCTTGAGAAAACGTAAAACAGGCGATGACATTAGTGAAAATGTGCCAGAGGATCCTAACGAAGATACAAATAAAGGAGCAAAAGGCTCGGATGTATCTCAAGTAAAATTATCTACTAAGGAAAGTAATCCAACGGATGATGATATTTGTACTATAAGTGATGAGGAAGACAGCAAAGATCGTAGACGGGAACCAAGTAGATTTGATCCGGCTGTCGAACCAGCCCAATTAGAAAGGTCAAAATTTAAATCGGTTAGGAATTTCTTTGGGGTGGACGAAGCAGTATATATTATGGACGCTAAGACTACTGGAAACATTGGACGATACTTAAATcACTCGTGCGATCCGAACGTATTTGTTCAGAATGTATTCGTGGATACTCATGACGTTCGTTTTCCTTGGGTCGCTTTTTTCGCTCAAAACTATATCAGAGCTGGTCAAGAATTAACATGGAATTACAGCTATGACGTCGGTAGTATACCgggaaaaagtattatttgtaAATGTGGTGCATCTAATTGCAGAGGTCgacttttataa
Protein Sequence: MAELKGTEVIELDSDEGDIQIRNENLKRKDTTPCHGTCINFVCTSGLNMKIAPSFACAYYGVNRCKKKKRLICEKCFEDSITHQQQLVSALIAKKPLLECDFPDHTMEVEISDSDDSDDERSKLMEQEDNYLPENVLSDIKEKIDDALLSIFNKYDIQHQIEESHKILKERWEKIDANTVELNKDIQKMMSDADSLRDRFYEDFKPQIQWLKELHIDDKPLENHLYPLVATKKVTQVRVSPNAGQSDTQPEIMPLERVDNKLEPADIPPLGPLIKPIPDVDSIVYVMKNPLMPWVKGKVQSIISKTPVHCRVKLLSKRYNSMVKSVYGKQLAVDVLCPVVVPVGTRVVAIFHDITGSDYHSGVIAEPPKSINKYRYLIFFDDGYAQYVTHKNIFIVAEASPRVWEDIPTDSREFIKKYMESYPERPMVKLQTGQIVKTEWNGKWWVARVNQLDASLVQMHFDADGRTEWIYRGSARLGPLFMELLKANARQHGYHAVNTPSRHCLPATTNKNNLPYVEYTSFNPELDDELAPVSKSDVLLKTLLNTSATTTTRSVPITSVPQQSRAVAKKSTTKRPPISNTTIQNSAEIKPSHSIVYYQPENKIKTKKYIPHKCGHECVAGISFTPDDLRGYSPLSIPLLCGWNRQISKFHKGRKVILYQAPCGVRLRNMEEVHQYLRITGSPMSVDLFDFDHWVNCLAEFSLDKCFVKINDLSYGVENVPIPCVNELDHALPDTIRYSTRREPTEGVNLNLDPEFLCCCDCEDDCQDKSKCQCWQLTIQGATLGGRVLNTAVGYVYKRLPEPVITGIYECNSRCKCNIKTCLNRVVQHPLTLKLQVFKTAPRGWGIRCLNDIPLGSFICIYAGRLLTEQSANEGGKNYGDEYLAELDYVEGVEGIKEGYESDVLEPEEVETNTTDDEKKSKTAEAKRGSYESDEDFNVDIPVNVNEAETASIRKRLRKRKTGDDISENVPEDPNEDTNKGAKGSDVSQVKLSTKESNPTDDDICTISDEEDSKDRRREPSRFDPAVEPAQLERSKFKSVRNFFGVDEAVYIMDAKTTGNIGRYLNHSCDPNVFVQNVFVDTHDVRFPWVAFFAQNYIRAGQELTWNYSYDVGSIPGKSIICKCGASNCRGRLL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01130816;
90% Identity: iTF_01130816;
80% Identity: iTF_00293723;