Basic Information

Insect: Cenopis cana
Gene Symbol: Hr39
Assembly: GCA_951800055.1
Location: OX637471.1:1457192-1478241[-]

Transcription Factor Domain

TF Family: SF-like
Domain: zf-C4|SF-like
PFAM: AnimalTFDB
TF Group: Zinc-Coordinating Group
Description: The ligand binding domain of nuclear receptor steroidogenic factor 1 (SF-1): SF-1, a member of the nuclear hormone receptor superfamily, is an essential regulator of endocrine development and function and is considered a master regulator of reproduction. Most nuclear receptors function as homodimer or heterodimers, however SF-1 binds to its target genes as a monomer, recognizing the variations of the DNA sequence motif, T/CCA AGGTCA. SF-1 functions cooperatively with other transcription factors to modulate gene expression. Phospholipids have been determined as potential ligands of SF-1. Like other members of the nuclear receptor (NR) superfamily of ligand-activated transcription factors, SF-1 has a central well conserved DNA binding domain (DBD), a variable N-terminal domain, a flexible hinge and a C-terminal ligand binding domain (LBD). [1, 8, 3, 11, 6, 5, 12, 10, 9, 2, 4, 7]
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 3 0.18 1.9e+03 -0.9 2.0 103 162 30 66 11 118 0.45

2 3 3.4e-08 0.00034 21.3 0.1 1 21 197 217 197 230 0.90

3 3 4.3e-65 4.3e-61 208.7 0.0 164 408 258 514 236 514 0.84

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	3	0.18	1.9e+03	-0.9	2.0	103	162	30	66	11	118	0.45
2	3	3.4e-08	0.00034	21.3	0.1	1	21	197	217	197	230	0.90
3	3	4.3e-65	4.3e-61	208.7	0.0	164	408	258	514	236	514	0.84

Sequence Information

Coding Sequence: ATGGAAAAGCTATTGGGCGCTCTCCACGGCTCCCCACTGCTGGGCCGACTGCCCAGGGTCCAGTCCAGCGCTAGCACCGACTCGGCCGTTCACTCCATGTACACACACAGTGTATACAGCAGTCCATCGGCAAGCCCACGCGCCTCGCGACACTACACGCCGTCCCTCTCTCGCAACAACAGTGACGCATCGCACTCTTCCTGTTACTCCTATAGCTCGGAATTCTCGCCGACACATTCGCCTGTCCAGGGCCGGCACCCCCACGTGGTGTACCGCGAACAGAATCCTGTGTTCCCGGGGTCGCCTCAGGACGACGAGGAGGCAGAGGACCGTCTCCATCACCACCAGGGGATCAGCAGACAGCAGCTCATCAACAGCCCGTGCCCTATATGCGGCGACAAAATCAGCGGTTTCCACTACGGCATATTCTCGTGCGAATCCTGCAAGGGTTTCTTCAAGAGAACGGTTCAAAACAGAAAGAACTACATGTGTCTCCGAGGTGGCAActgtcctgtcacggtcgccaccaGGAAGAAGTGCCCCGCTTGTAGGTTCGACAAGTGTCTCGGCTGTGGCATGAAGCTGGAAGCTATAAGAGAAGACAGAACTCGGGGCGGCCGGTCCACGTACCAGTGTTCGTACACGCTATCGGGAGCTGTCTCTACTGGTTCTTTACTGTCTGCTGCCGTGCCACCGACCCTTCGGCATGCATCCAGTCTAACTTGCGTGAACGGTCCCGGATCGTACAGTCGAGGCGAGTCTAGCAGCAGTCGTTTAACGCCAGATATACCCCCGTTATTGCAGGAAATAATGGATGTGGAGCATCTCTGGCAATACAACGAGACAGAACTGAGTCGCCTCGGCAAGTCTGGGCTAAGTCCGTCCGCCAACCCGCTGCTAGCAGCGTCTGGCATCACGGCGCACAACTCCAGCCCGGACTTCTTAGCCGACTTGTGCAACATAGCCGACCACAGACTGTACAAGATCGTCAAGTGGTGCAAGAGCTTGCCGCTATTCAAAAACATCTCCATCGACGACCAGATCTGCCTGCTGATCAACAGCTGGTGCGAGCTGCTGGTGCTGTCGTGCTGCTACCGCGGCGTGGGGACGGTGGGGGAGGTGCGCGTGGGGGGTGGGAGGGGGATCACCCTGCAGCAGAGCGCCAAAATGGGGTTAACTCCATGCATAGAGCGTATGCTGAGCTTCACCGACCATCTCCGACGGTTGAGGGTCGACCGGTACGAGTACGTAGCGCTGAAGGTCATCGTACTCCTCACCTCCGACGCCCCAGAGTTGCGTGAAGCGGAGAAAGTGCGAGCTTCGCAGGAGAAAGCCCTCGCCGCGCTCCAGGCCTACACGGCCGCTCACTCGCCCGACACGCCCGCCAAGTTCGGAGAGCTGCTCCTGCGCATACCGGAGTTGCAGCGGACTTGTCAGTTTTTCATGCAAGTCGGCAAGGAGATGCTGAATCCAGCGaacaaaaacaaagatggcgacGGCCCGAGCTTCAATCTGCTCATGGAACTGCTCCGAGGTGACCACTGA
Protein Sequence: MEKLLGALHGSPLLGRLPRVQSSASTDSAVHSMYTHSVYSSPSASPRASRHYTPSLSRNNSDASHSSCYSYSSEFSPTHSPVQGRHPHVVYREQNPVFPGSPQDDEEAEDRLHHHQGISRQQLINSPCPICGDKISGFHYGIFSCESCKGFFKRTVQNRKNYMCLRGGNCPVTVATRKKCPACRFDKCLGCGMKLEAIREDRTRGGRSTYQCSYTLSGAVSTGSLLSAAVPPTLRHASSLTCVNGPGSYSRGESSSSRLTPDIPPLLQEIMDVEHLWQYNETELSRLGKSGLSPSANPLLAASGITAHNSSPDFLADLCNIADHRLYKIVKWCKSLPLFKNISIDDQICLLINSWCELLVLSCCYRGVGTVGEVRVGGGRGITLQQSAKMGLTPCIERMLSFTDHLRRLRVDRYEYVALKVIVLLTSDAPELREAEKVRASQEKALAALQAYTAAHSPDTPAKFGELLLRIPELQRTCQFFMQVGKEMLNPANKNKDGDGPSFNLLMELLRGDH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00660411;
90% Identity: iTF_00660411;
80% Identity: iTF_00289734;