Basic Information

Gene Symbol
Rreb1
Assembly
GCA_900474305.1
Location
UCOJ01001551.1:8043-15590[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 16 0.0032 0.27 11.9 0.4 1 23 94 116 94 116 0.96
2 16 0.00032 0.027 15.0 0.1 1 23 132 154 132 154 0.97
3 16 2.3e-07 1.9e-05 24.9 1.3 1 23 160 183 160 183 0.98
4 16 0.2 17 6.2 0.2 6 23 279 297 276 298 0.82
5 16 0.044 3.7 8.3 4.0 2 23 304 326 304 326 0.95
6 16 1.1 92 3.9 0.3 1 19 375 393 375 395 0.90
7 16 0.07 5.9 7.7 0.1 1 23 509 531 509 531 0.96
8 16 2.5e-05 0.0021 18.5 0.3 1 23 540 562 540 562 0.98
9 16 0.0012 0.1 13.2 2.8 1 23 568 591 568 591 0.97
10 16 0.00093 0.078 13.6 2.1 1 23 964 987 964 987 0.97
11 16 0.00065 0.055 14.0 0.1 3 23 1277 1297 1275 1297 0.97
12 16 3.2 2.7e+02 2.4 5.7 1 23 1303 1326 1303 1326 0.96
13 16 0.0083 0.7 10.6 2.3 1 23 1366 1390 1366 1390 0.97
14 16 3.1 2.6e+02 2.5 3.3 1 23 1533 1556 1533 1556 0.89
15 16 0.011 0.94 10.2 0.4 2 23 1608 1629 1607 1629 0.94
16 16 3.2 2.7e+02 2.4 5.6 1 21 1635 1655 1635 1656 0.95

Sequence Information

Coding Sequence
ATGGCCGGCAGTCGAGGCTACGCCcccgctatatactctcacaGTGTTATTCCAAAGCGCAGCATCCGACGAGAGTCTGCGCAGACTCTCGacgttctcttcttcttcttcttcttctgtgaGGGTGGAGAACTGACTGCCGAGACTGGACCTGATCACCGCGACGGCGAGAGGCAAACGGATGTTGCATCATCAGTACTGTACAACCTTCCTAATTTCAAGGTCGAaccacagcagcaacagcagcaaagtCCAACACAACAGTCAGGAGAAGGAAGCCACCCGTGTCCGGCCTGTCCGCTGGTGTTGTCGAGTTCACGCGAGCTGACACATCACCTACGCGCTCACAACTCACCCCGAAGTACGACCGACTGCAGCGGCGAGGAGGTCGACTACGCCTGCGGCGTCTGTCACAAGGTCCTCAGTTCGGCCAGTTCTCTCGACCGCCACGTACTCGTGCACTCAGGCGAGAGACCTTTCAAGTGCAAGTACTGCGACATGGCTTTCACGACCAACGGCAACATGAACAGGCATCTCAGAACAGCCCACAGGACGGCCTCGCCGTCCCACAGCTGTACCGATTCCGAAGCCAGCAGCGATTCCGAGCGACCGCTCAAGAGGAAACTCATCCAGGAGGAGTACAACAACAACGAGATCGCCAAGAGGAACTCACCCGAACTCATTGTCTCCCAGACTAAGAGACGCTGTCCTGACTACGCCGACGAGGCCGATAGTCAAAGGAGACACAAGATACTTCTAGGCAACGCCAGGAACGAAATCCGCGGTGGATACTCTGACTCGCCACCCTCGGCACTCGCTCTCGGCTGCGCCGCGTGCGGTCGTCAGGACTTTGTCACACCGGCGCAACTCGAGACTCACATGGAACGCCATCACCCTGATGTACCTGCCAAGTGCGAGAGCTGCAACATCAGCTTCAAGAACCACCGGACGCTGAACCTCCACCGATTTATGAGCCACTTTAGCGAGGGTGCCAAACACATGCGCAACTCGGTCGTCGGATTCAACGACCTGACCTTCGTCGACTTCTCCTCAGACAAGTTCCCGACCATCGCCAGGGCCGTCTGCGAGCAGTCGCTCCATCGACCTGCCTCCGGAGAGGCCTACCAGTGCTCCAAGTGCCTCCGAGCTTTTCCCTGCCGATCGGCACTCGATGCTCACGAGATCGACTGCGGCAGTCAGAGCATCGAACAGCATCGACTACACGCTGACGACCAATCTGGCAGGGACGACTTCTTCGCCGGGCTGGACCTTCAGAACAAGGCTGCTCTGGCCGAGGCCAAGGAGGGCAAGGACCTCGCCGATATCCAGAGCATCATCAGCGTCACCTCCGGACCGATCCTCCAGAACCTCAACCGATCCGACGCCTGCACCCCTGACAACTGCAAGATCAAGCAGAGCTTCGGATCGTCCGGTTCCTCCAGCAATCCCTGCTCCGAGTACCACGAGGAGGAGGCCCAGGATGCGTTCGCCGCCGAGTTCCGCAAAATGAAGATGAAGGGCGAGTTCCCCTGCCGACTCTGCAGCGCCGTGTTCCCCAACCTCCGCGCTCTCAAGGGCCACAATCGAGCCCACATGGGTGTCGGTCCAGGTATGCCCTACCCCTGCAACATGTGCCCCTACAGCAGCACCGACAAGGCCACCCTCGTCAGGCATCTCAGGTCGCACAACGGCGACCGACCCTACGAGTGCTCGCTCTGCAACTACGCCTTCACCACCAAGGCCAACTGCGAGCGACACGTGAGGAACCGACACGGCAAACTCTCCCGCGAGGAGATCAAGAGCGTGCTCATCTACCATCCCAGCGAGGACTCCACCAACGACGCAAGCCTCGAGAGAGCGTCGCCCAGAGGCTCGTCCCTCATCCGCGACGAGGTCCGCAAGACCCTGGTCTACTCCAGCGAACGAGAGGAACAGCTGCCGGTTGTTCAATATCCTCAAGCTGGCGAGCTGAAGATCAAGGACGAGGCCAAGCTCAAACAGCCAGGACTCCCCGGACTCCACGCCATCGGCAACCTCGAGCTCTTCCCCAGACCGCCCCAGTCTCTCGAGCTGACCTACCACagcgacgagcagcagcagcaacctgGCAACGATGTCAAGGAGGAAGACCTCGACTCGAGGTCATCGGACGGCAGCGTGTCTCTAGTCAGCGAAACCAATGCGGACGCCGCACACCAAAGTATCCAGGCCAGTCCGATGGACCTGAAGAAGTCCAACAACTCGTCCCAGGCCGAGGACGCGCCGCTCGACCTCAGCATGGACGTGCTCGACCTCAGTCGCAAGGCCAAGGCTGCCGCCGCAGCTGCCGCGGCTCGCAAGGCCGACTCAATCAACGGCGAGGATCCTAGATCACAGGAGAGCAGCAACCCCGGTAATGGCCTGTACAACACGACGAACCAGTCGCTGCTGTCCCACGCTCTATTCAAGGGCCATCCGCCCTCGCAGTTCGAGACCTTGTACGCGAATGCTCAGATGCTCTACAGGAACTTTGGAACGTTCcctgcggcggctgctgccGGTATTCTCCAGCCGTACCTCTTCAACCCTCATATCTTCGGGCAGACCTGCGCCATGAAGGACAGGATGCACAATGAGCTGATCCGTGGACTCCAGACCAGCGGAGGTAGCCTCGTGGAACCACCGCAGGTTCCGAGCTACGGCGCCGCCGCTTTTCCCCAGCAGAGCAGTCGTCAACCGGATCAAAACAACTCCGGTTACGCCAATCTCATGAGCAAGAGCGTGGCATCGTCGTCCAGGAACAAGAACCACGACAACAACTCGCAGTCGTCCAGCTCCGTGAAAATGGTTATCAAGAACGGCGTGCTCATGCCCAAGCAGAAGCAGCGACGCTACAGGACCGAGCGACCGTTCACCTGCAAATACTGCTTGGCCAGGTTCACCCTGCGCAGCAATATGGAGCGACACatcaagcagcagcatcctGGCCACTGGAGCCAGAGACCCAGGGGTGGACACTCGACTCGAGGCAGACCACCGGCGAACCCGCCACCGCTTCTCCAAAATCTGGGACCGAGCACGTCGCACCATCACGCCCAACAACAGACGTCACAGGCCCACGGTGGAGTGATGCCGAAGCTTGGACAAcaagtcgctgctgctgaccaCGGCAAACACGCCATATCCGATCAGGTCAAGTACGCCATCTTGGCCCAGCAACTCAAGGGTGGAAGCAAGCCCGAGGATAACGACTCCGACGAGGAGCTCGTCATCGACGAGGAGACGGAGAAGGAGCACAGGGAGCCCACCGAGAGAACCCTCAGTCTGCTCAGAGACAAACTCGAGGCTAACATCGAGAACAAGGGCTGCGAGGACGTGGATATGAAGGAGGTCAGGGTCAAGGAGGAGTTCAAGGAGAAGATCAAACAGGAGATCGAGAGCCACATGGAGCACAAGAACGACGAGCACGACGTGCTCAACATCAAAGAGCGAGACGACGAGtccgacgaggaggaggacgacgacgagatcaCCTCCATCGTACCCGAGGCCATGGTCAAGACCGAGCTTCGCGATCTCAAGGAGGACCAGGAGGATCTGGCCAGCGTATCCGAGATCCTGGACAACGCTTCCCAGCACTACCAGCACTTTCAGTCGCAGTACATGAGCGACGAGGAGGGTCTCGTCGCCTCGACGAGCGACTGCAACCAGTCGGGCAGCGACGAAAAGTCGGACTCGGTCAACTCGGCCAACTCCGGCCACTCGTCcagctcgaagaagaagaaaaagaagatgaagaaaaagaagaagaagaagtccgCCTACTCGATGGCTCCCAACCGAGTGATCTGCCCGTACTGCGAGCGACCCTTCCCCTGGACCTCCTCGTTACGTCGACACATCCTCACACACACGGGTCAGAAGCCCTTCCAGTGCATGCACTGCGCGCTTCTCTTCACCACCAAGTCCAACTGCGATCGTCACCTGCTGCGCAAGCACAAGAACAAGATCGAGAAGCTGCGCAGGACCCGCAGCACCTCGTCGCCAGAACTCCAGGAGCCACCgagcatcaacaacaacagccaGTTCGCCATGAGAAACGTGCCCGAGCGTCCCTACAAGTGCAACCAGTGTCCCAGCTCGACCTTCTCCACCCTCGGCAATCTTAAGAAACACAAGTCCACGAAGCACCAGTACCAGCAGCGCCATCTGGCGCCAAAATCGCGACCGGAGTCGCCCTGCAGCGAACCCCAGCACAGCCCCCAGGACTGCAGTCCAGCTCAGGAAGAGACTCACGTCCAAGAGGAGTCTGTCCTTCCGGCTCAGGATTGCAACGTCCAGGAATGCGCTGAAGCTCAGGATTGCCAGAAACAGCAAGGTACCGGTACCGACCAGAGCGGCTACGAGAGCCAGTCGTCCGGGGTCTCAGATAACATGGCCGAGAACCTGGCCGAACGTCTCGAGGGCATGAGCTCGACGCCCATCGCCGATCCAGCCAAGAacgccaacaacaacaacaacaacaacaacgccTCCAGGAAGAACTCGCCCACCTCGTCGCCGGGACCAAacaacagcggcagcagcagcagcgccaacAACTCCGAAGCTGCGCCCTTCAAGTGCCACCTCTGCGACAGCGGCTTCTCCGAGAGAAACGACTGCCTCGAGCATATCAAGGACAACCACGAGCACTCCTACGAGATGCTCGTCGCCAAGGGTGCCCTGGAGATGGACTTTGACGGTGCCGACGAACCCATGCCACCagcgccaccaccaccaccccAGAACCCCAGCGACGGTGAAGGCAGGCGGTTTCCCGACTACAGCAACAGAAAGGTCGTTTGCGCCTTCTGCATGCGTCGTTTCTGGTCGGCAGAGGACCTTCGTCGCCACATGCGCACGCACACAGGCGAGCGTCCATTCTCCTGCGACATCTGCTGTCGGCGCTTCACCCTGAAGCACAGTATGCTTCGTCACCGCAAAAAGTGCGAGTCCTGCATCGACTCCAGCATGTACGTGGGTACCAGTGGCGACGAGGACACCGGCATGAGTCAACCGCCCACGATAACCCCTCGCTCGCAGCAACAGTCATCCCAGatggcgcagcagcagcaacgcgcCTCACTACCACAGGTCGCGAGTGTCGCCACTGCCGACGCTGCACCTAGTGGACTCATGCGGTTCAATCCATACGAGAAGCTGACTACCCTCACGGGCAAACTCAGCGCTGGTGTCTCTCCGAGTATCGAGGCCAGCGACAACAACGACAACGATCTCATCTCCAACCTGCTGGGCATCAGGGACAAGAGCATCATCGACCGGGTACTTCAGGCCTCAGCAGACGACGCCGCCAAGCTTCTGGGTGTCAAGGGAAACCACGAATGA
Protein Sequence
MAGSRGYAPAIYSHSVIPKRSIRRESAQTLDVLFFFFFFCEGGELTAETGPDHRDGERQTDVASSVLYNLPNFKVEPQQQQQQSPTQQSGEGSHPCPACPLVLSSSRELTHHLRAHNSPRSTTDCSGEEVDYACGVCHKVLSSASSLDRHVLVHSGERPFKCKYCDMAFTTNGNMNRHLRTAHRTASPSHSCTDSEASSDSERPLKRKLIQEEYNNNEIAKRNSPELIVSQTKRRCPDYADEADSQRRHKILLGNARNEIRGGYSDSPPSALALGCAACGRQDFVTPAQLETHMERHHPDVPAKCESCNISFKNHRTLNLHRFMSHFSEGAKHMRNSVVGFNDLTFVDFSSDKFPTIARAVCEQSLHRPASGEAYQCSKCLRAFPCRSALDAHEIDCGSQSIEQHRLHADDQSGRDDFFAGLDLQNKAALAEAKEGKDLADIQSIISVTSGPILQNLNRSDACTPDNCKIKQSFGSSGSSSNPCSEYHEEEAQDAFAAEFRKMKMKGEFPCRLCSAVFPNLRALKGHNRAHMGVGPGMPYPCNMCPYSSTDKATLVRHLRSHNGDRPYECSLCNYAFTTKANCERHVRNRHGKLSREEIKSVLIYHPSEDSTNDASLERASPRGSSLIRDEVRKTLVYSSEREEQLPVVQYPQAGELKIKDEAKLKQPGLPGLHAIGNLELFPRPPQSLELTYHSDEQQQQPGNDVKEEDLDSRSSDGSVSLVSETNADAAHQSIQASPMDLKKSNNSSQAEDAPLDLSMDVLDLSRKAKAAAAAAAARKADSINGEDPRSQESSNPGNGLYNTTNQSLLSHALFKGHPPSQFETLYANAQMLYRNFGTFPAAAAAGILQPYLFNPHIFGQTCAMKDRMHNELIRGLQTSGGSLVEPPQVPSYGAAAFPQQSSRQPDQNNSGYANLMSKSVASSSRNKNHDNNSQSSSSVKMVIKNGVLMPKQKQRRYRTERPFTCKYCLARFTLRSNMERHIKQQHPGHWSQRPRGGHSTRGRPPANPPPLLQNLGPSTSHHHAQQQTSQAHGGVMPKLGQQVAAADHGKHAISDQVKYAILAQQLKGGSKPEDNDSDEELVIDEETEKEHREPTERTLSLLRDKLEANIENKGCEDVDMKEVRVKEEFKEKIKQEIESHMEHKNDEHDVLNIKERDDESDEEEDDDEITSIVPEAMVKTELRDLKEDQEDLASVSEILDNASQHYQHFQSQYMSDEEGLVASTSDCNQSGSDEKSDSVNSANSGHSSSSKKKKKKMKKKKKKKSAYSMAPNRVICPYCERPFPWTSSLRRHILTHTGQKPFQCMHCALLFTTKSNCDRHLLRKHKNKIEKLRRTRSTSSPELQEPPSINNNSQFAMRNVPERPYKCNQCPSSTFSTLGNLKKHKSTKHQYQQRHLAPKSRPESPCSEPQHSPQDCSPAQEETHVQEESVLPAQDCNVQECAEAQDCQKQQGTGTDQSGYESQSSGVSDNMAENLAERLEGMSSTPIADPAKNANNNNNNNNASRKNSPTSSPGPNNSGSSSSANNSEAAPFKCHLCDSGFSERNDCLEHIKDNHEHSYEMLVAKGALEMDFDGADEPMPPAPPPPPQNPSDGEGRRFPDYSNRKVVCAFCMRRFWSAEDLRRHMRTHTGERPFSCDICCRRFTLKHSMLRHRKKCESCIDSSMYVGTSGDEDTGMSQPPTITPRSQQQSSQMAQQQQRASLPQVASVATADAAPSGLMRFNPYEKLTTLTGKLSAGVSPSIEASDNNDNDLISNLLGIRDKSIIDRVLQASADDAAKLLGVKGNHE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01037292;
90% Identity
-
80% Identity
-