Basic Information

Gene Symbol
-
Assembly
GCA_900474305.1
Location
UCOJ01000099.1:173964-176735[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 14 0.58 49 4.8 0.4 2 21 120 138 119 139 0.85
2 14 0.00056 0.047 14.2 1.5 3 20 147 164 145 167 0.95
3 14 0.00085 0.072 13.7 0.3 1 23 173 196 173 196 0.92
4 14 6.5e-06 0.00055 20.3 0.8 1 23 202 224 202 224 0.98
5 14 1.5e-05 0.0013 19.2 1.0 1 23 372 394 372 394 0.98
6 14 0.011 0.89 10.2 0.2 2 20 404 422 403 424 0.92
7 14 0.0003 0.025 15.1 2.6 1 20 446 465 446 468 0.92
8 14 0.0021 0.18 12.4 0.5 1 23 473 496 473 496 0.95
9 14 1.3e-06 0.00011 22.6 0.3 1 23 502 524 502 524 0.98
10 14 0.00013 0.011 16.3 4.2 1 23 531 553 531 553 0.99
11 14 0.00036 0.03 14.9 0.4 3 23 561 581 559 581 0.97
12 14 0.0018 0.15 12.7 0.1 1 23 587 610 587 610 0.96
13 14 0.029 2.5 8.8 0.2 1 23 624 646 624 646 0.97
14 14 0.036 3 8.6 0.0 3 23 876 896 874 896 0.96

Sequence Information

Coding Sequence
ATggaaacaaatgaaaatgaacACTATGTTGCATATTCCTTAGATAATGCAAATGAAGgTTTACAAGATAATATATCTCACGAAGAAATCTGTGAACCAGTTGATGAATGCGTACTGCAAGAAAGTTTAACTGAAGTCACTGTTTGCGATGAGAATTCAGATATGACAGATGCACAAGTTGCTGTAGATATCTTATCAGAAAATTCTGAGGTTGATGCAGAACATGGTGCTGTTGTATATCCGatttatattaagaaaaaaatatcacaacaGTTTACAACTGGAGATGAATCAATGGCTGTGGAAGCCTTACGTCAATTAGGTGGAATGTATCCTTGTTTTGAAGATAAGAAAGTTACATGTACTAATTGTAGTAATACGTTTAAACAAGCCGATTTAGACAAACATCGATCTACGTGTACATCTGATAAACAAATTTGTAAGACATGTGGTGAAAGATTTGAAAGgaaaatagatttaaataatcatatgGTATGCCACCAAGTAGACCGACCTCATGCTTGTAGAACTTGTGGGAACCTATTTCGCTCCAAAGCTAATTTACAGGCTCATATAGCTGAGGTTCATCAAATTGAACGTCCTCACAAATGCTCAGTTTGTGGAGCAGATTTTCAAAGACCATCAAGTCTTTCTAATCATATGAAAATTCATAGTTATGTTGCAGGAAGAGCATTAATGCAAGGAAATAACACAGCTACgagtattgaaaatttcaaaactatatCCAATTCACAAGATGCATCAGTTTTAACAACTACAGTTGAAACTATACAGAATTTTGAAATACCTCAAGTACAATGGGCTGTAcaaacttataattttaccAATGATGATCAAGGCAATATTGAAGGGATTGTTAATCAATCTGACAAAGTTGATACATTACAAGAATTCACTGTGTTACCAAATGGTGAAGTAGCACAGTTTGAATATACTACCCAAAATGAAGTTGGAAATCAAATTGCTCAAGAATATAGCTTAACTCTAAATACTTTTAACAGTTCTGATACCATATTGAAACTAGAAGCTACTGGTTATACCAATGATAATAAAAGTGCTTATGttgatataaatatgcaaGAAAATAGAGGACATACCTGTAGCCAATGTGGGGTAAGTTTTGCACGTGCGTCATCTTTATCATTACATGAAAAGACTCATACTAAAAGTGATGTGGGCTCTCCAGTAGAGTGTGAATATTGTGATAAACAATTCCAAGATGCAAATTTCTTAGCTACTCACCATGCTTCTTGTGccaaaaaattaatgcaaagcaatacagaaaaaaatatatctaatgCAAAATGGGGTAAACATGCTTGTTCAGAATGtggtaaaaaatttactactaaacaaaaaatgtttagacATCAATGGATTCATAGAAAGAAAACACATTCATGTGAGATTTGTGGTTCACAGTTTGAGAAACAATCTGAGTTAGATGAACATAGATTGTCAGCACATCCAGGAGATTCACCATTTACTTGTACTGAATgtggaaaaagttttgtatCTCGACAAGGACTTTGGGAACATGGTAGGACGCATGCAGGAAGTCCAGCTTATTTTCAATGTGACACATGTTCGAAGACTTTTTCATCTCGTCAAGGATATTTAATTCATCATCGCACACATACAGGTGAGCGACCATATGGTTGCAAATTTTGCTGGAAAGCTTTTCGTGATGGAGGAACTTTGAGAAAACATGAAAGAATACACACAGGTGAAAGACCCCATGTCTGTCCATTATGTGCAAGAGCTTTTAATCAGAAAGTGGTTTTACGTGAGCACGTTCGGTGGGTTCATGCTGcaggaaaaaatgaaactgaTATTACTGAGCCACCATTTCCATGTCCGTTATGTGAAACCCTAACTCAAGATCGAGATGAACTATGTGCTCACATTGTCAAACATTCAGATCAGTTGATAGCAGAAGCTAAGGCTAAAAGTAACAATGTGACTGCAAAAATGAAGactcagaaaaagaaagttaaagCACTAACTTCTAAGACAAGAAAGACTAATTCAAAAGCATCAGGTGGAAGACTAATTTCTGTGACAGAACAAACTGAAGCATTACTTTCAATTACTGAACAAACAGATACCGCAGAAGAAATACAAACTGAGTTTGTAGTAGTCAAAAATGAATACGAAGAAGATGTGTGTATTAAAACGTATACACAATCGAATGACATGACTCATACTGAAAGTGGAAATGAGTCTATCAATGTTATAACTATCGCTAAATCTTCCAATAATAAAGATGAAGAGCATAACATGCATTTGATTCCTTTTACTGCTGCAGGTGAAACCATACATCTTATTTCAAATAACAACCAAAATAATACATTGCATTTTATatcaaagcaaaacaaaaattcaccGGTTTTAGCAATTCCCAATCCTCAAACTAgtgaacatttttcaaaccaaCTTAGCCAAATAACTGATTCTGAGACATCAATAGATGcaattcataaaaaagatACTGAAGAGCTTCACGCAGTAACAATGTTGATTGAGCCAGTAGATACTAATGAACACAAGTTTGAAGAAGTaataaatgaagaagaaaCTGAAGATGAAAGTGAAGAAATGATATGTGGCATTTGTGGAAGTGACTTTGAggacaaaaatgtattaatgGAACAtgtgaaaattcatatataa
Protein Sequence
METNENEHYVAYSLDNANEGLQDNISHEEICEPVDECVLQESLTEVTVCDENSDMTDAQVAVDILSENSEVDAEHGAVVYPIYIKKKISQQFTTGDESMAVEALRQLGGMYPCFEDKKVTCTNCSNTFKQADLDKHRSTCTSDKQICKTCGERFERKIDLNNHMVCHQVDRPHACRTCGNLFRSKANLQAHIAEVHQIERPHKCSVCGADFQRPSSLSNHMKIHSYVAGRALMQGNNTATSIENFKTISNSQDASVLTTTVETIQNFEIPQVQWAVQTYNFTNDDQGNIEGIVNQSDKVDTLQEFTVLPNGEVAQFEYTTQNEVGNQIAQEYSLTLNTFNSSDTILKLEATGYTNDNKSAYVDINMQENRGHTCSQCGVSFARASSLSLHEKTHTKSDVGSPVECEYCDKQFQDANFLATHHASCAKKLMQSNTEKNISNAKWGKHACSECGKKFTTKQKMFRHQWIHRKKTHSCEICGSQFEKQSELDEHRLSAHPGDSPFTCTECGKSFVSRQGLWEHGRTHAGSPAYFQCDTCSKTFSSRQGYLIHHRTHTGERPYGCKFCWKAFRDGGTLRKHERIHTGERPHVCPLCARAFNQKVVLREHVRWVHAAGKNETDITEPPFPCPLCETLTQDRDELCAHIVKHSDQLIAEAKAKSNNVTAKMKTQKKKVKALTSKTRKTNSKASGGRLISVTEQTEALLSITEQTDTAEEIQTEFVVVKNEYEEDVCIKTYTQSNDMTHTESGNESINVITIAKSSNNKDEEHNMHLIPFTAAGETIHLISNNNQNNTLHFISKQNKNSPVLAIPNPQTSEHFSNQLSQITDSETSIDAIHKKDTEELHAVTMLIEPVDTNEHKFEEVINEEETEDESEEMICGICGSDFEDKNVLMEHVKIHI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00144041;
90% Identity
iTF_01274734;
80% Identity
-