Basic Information

Transcription Factor Domain

TF Family: zf-GAGA
Domain: zf-GAGA domain
PFAM: PF09237
TF Group: Zinc-Coordinating Group
Description: Members of this family bind to a 5'-GAGAG-3' DNA consensus binding site, and contain a Cys2-His2 zinc finger core as well as an N-terminal extension containing two highly basic regions. The zinc finger core binds in the DNA major groove and recognises the first three GAG bases of the consensus in a manner similar to that seen in other classical zinc finger-DNA complexes. The second basic region forms a helix that interacts in the major groove recognising the last G of the consensus, while the first basic region wraps around the DNA in the minor groove and recognises the A in the fourth position of the consensus sequence [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 1.5e-05 0.1 14.5 0.0 6 52 63 109 60 111 0.92

2 9 0.054 3.8e+02 3.1 0.0 23 45 108 130 105 137 0.82

3 9 0.14 1e+03 1.7 0.0 23 52 136 165 131 166 0.84

4 9 0.046 3.3e+02 3.3 0.2 23 44 164 185 154 194 0.84

5 9 0.85 6.1e+03 -0.8 0.0 23 44 192 213 186 217 0.85

6 9 0.0014 10 8.1 0.2 22 47 219 244 214 251 0.87

7 9 0.72 5.1e+03 -0.5 0.1 23 52 248 277 242 277 0.85

8 9 0.39 2.8e+03 0.3 0.0 23 43 276 296 272 305 0.78

9 9 0.00085 6 8.8 0.2 23 48 304 329 297 332 0.92

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	1.5e-05	0.1	14.5	0.0	6	52	63	109	60	111	0.92
2	9	0.054	3.8e+02	3.1	0.0	23	45	108	130	105	137	0.82
3	9	0.14	1e+03	1.7	0.0	23	52	136	165	131	166	0.84
4	9	0.046	3.3e+02	3.3	0.2	23	44	164	185	154	194	0.84
5	9	0.85	6.1e+03	-0.8	0.0	23	44	192	213	186	217	0.85
6	9	0.0014	10	8.1	0.2	22	47	219	244	214	251	0.87
7	9	0.72	5.1e+03	-0.5	0.1	23	52	248	277	242	277	0.85
8	9	0.39	2.8e+03	0.3	0.0	23	43	276	296	272	305	0.78
9	9	0.00085	6	8.8	0.2	23	48	304	329	297	332	0.92

Coding Sequence: ATGGATGTTGAAAAGTTTGAGATAAAAGAGGAAACTAAGGTTATTCTTGAACCAAAAATTgatTCAGGCGGTACGTCTAATCCCGATAAATCTAATGAAGAACAGTGCATTAATAGTGATTATAAATATCTTAGCGATTTTAAAGAGAGCGATAGTGAAACGACTGATAGTACGATAAGTAGCGATTCGAAATTACCGACGCAGACCAGTGACAAGAAATCGCGTGGTAGCGCTACTAAGCCATATAAGTGCGATATTTGTGAAAAAGTGTTTACGCAAAACGGTACTCTGAAACTTCACGCGGTAATACATAGTGGGGCTAAGCCATTCAAATGCGATATCTGCGAAAAGGCATTCAATCTGCGATCGAATCTAAATAAGCACTTGTTAACGCATAGCGATTctaagccatttaagtgtgatGTTTGCGATAAGAGATTCAATCAGAAAAAATATCTGGCAACCCACATGTCGATACACAGCGTGACTAGACCGTTTAAGTGTCACATTTGCCCGAACGAATTCCGACAGAAAGCGCAACTAACAAATCACGTTTTAACGCACAGCGATGTTAAACCGTTCAAATGCGACGTCTGCGGTAAGGGATTCGGGCAGAAGCGCGATATGAATATTCATATGTTATCGCATACGAACGCTCAACCGTTCAATTGCGATATCTGTCAAAAGCGATTTAAACACCAGAAATATTTGACGCGGCATCTGTCGATACATACCGGTGTTAGGCCGTTCAAATGCGAGTTGTGTCAAAAAGATTTCAGATGGAAATGCGATTTAGCCGCGCACTTGGTGATACATAGTAATTCTAAGCCGTTTAAATGTAACATCTGCCCGAAGTCTTTCAATCAGAAAAAATATCTAACCATACATTCCCTAATACATAGCGGTATTAAACCATATAAATGCAATATATGCAACAAAGAATTTCGACAGAAAACGCAACTAACCCATCATTTGATATTATCGCATACTGTTGTTTCCAAATGA
Protein Sequence: MDVEKFEIKEETKVILEPKIDSGGTSNPDKSNEEQCINSDYKYLSDFKESDSETTDSTISSDSKLPTQTSDKKSRGSATKPYKCDICEKVFTQNGTLKLHAVIHSGAKPFKCDICEKAFNLRSNLNKHLLTHSDSKPFKCDVCDKRFNQKKYLATHMSIHSVTRPFKCHICPNEFRQKAQLTNHVLTHSDVKPFKCDVCGKGFGQKRDMNIHMLSHTNAQPFNCDICQKRFKHQKYLTRHLSIHTGVRPFKCELCQKDFRWKCDLAAHLVIHSNSKPFKCNICPKSFNQKKYLTIHSLIHSGIKPYKCNICNKEFRQKTQLTHHLILSHTVVSK

Sequence clustering based on sequence similarity using MMseqs2