Basic Information

Gene Symbol
-
Assembly
GCA_963931975.1
Location
OZ008342.1:15405962-15414543[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 29 8.9e-07 6.8e-05 23.6 1.4 1 23 205 227 205 227 0.99
2 29 0.00057 0.044 14.8 0.7 2 20 257 275 256 277 0.92
3 29 2.5e-06 0.00019 22.2 1.3 1 23 305 328 305 328 0.97
4 29 8.3 6.3e+02 1.7 0.2 2 12 349 359 348 362 0.86
5 29 0.0086 0.66 11.1 1.8 1 23 379 402 379 402 0.97
6 29 0.0069 0.53 11.4 0.2 1 23 425 447 425 447 0.96
7 29 0.00058 0.044 14.8 2.0 2 23 490 511 489 511 0.96
8 29 0.00057 0.044 14.8 3.9 2 23 552 574 552 574 0.97
9 29 0.00027 0.021 15.8 0.8 1 23 624 647 624 647 0.95
10 29 0.014 1.1 10.4 0.1 1 23 705 727 705 727 0.96
11 29 0.0038 0.29 12.2 5.2 2 23 739 760 738 760 0.97
12 29 0.011 0.83 10.8 1.0 2 23 772 793 771 793 0.96
13 29 0.0065 0.5 11.5 0.7 1 23 803 825 803 825 0.98
14 29 0.16 12 7.1 4.5 1 23 854 876 854 876 0.97
15 29 0.00014 0.011 16.7 1.3 1 23 887 909 887 909 0.97
16 29 9.6e-06 0.00073 20.4 0.5 1 23 917 939 917 939 0.98
17 29 0.00017 0.013 16.4 0.8 2 23 959 981 958 981 0.97
18 29 0.052 4 8.6 0.2 1 23 999 1021 999 1021 0.94
19 29 0.14 10 7.3 2.7 1 23 1028 1050 1028 1050 0.97
20 29 0.0082 0.63 11.2 2.1 2 23 1061 1083 1060 1083 0.95
21 29 0.0058 0.45 11.6 0.1 2 23 1106 1127 1105 1127 0.95
22 29 1 80 4.5 0.2 2 20 1131 1149 1130 1150 0.91
23 29 0.0063 0.48 11.5 0.2 2 23 1208 1229 1207 1229 0.95
24 29 1.4 1.1e+02 4.1 4.5 5 23 1239 1257 1236 1257 0.94
25 29 0.015 1.1 10.3 0.7 2 23 1268 1290 1267 1290 0.95
26 29 0.18 14 6.9 2.6 2 23 1307 1325 1307 1325 0.88
27 29 3.1 2.4e+02 3.0 0.9 2 21 1329 1348 1329 1349 0.93
28 29 0.034 2.6 9.2 1.9 2 23 1430 1452 1429 1452 0.96
29 29 0.5 38 5.5 2.6 2 21 1490 1509 1489 1510 0.94

Sequence Information

Coding Sequence
ATGGCTCTCAAACTAGGAAAATGCAGGCTTTGTTTGAAATTGGGTGACTTCTATTCAATATTTACTGTCGACAATGCCCTTCAGCTCGCTGATATGGTTATGGAGTGTGCCCGGGTGAAAgtatatgaaggtgatgggctCCCTGATAAAATATGCTCAGAGTGTATACAAAAACTCAGCAGTGCATATATTTTCAAGCAACAGTGTGAAAGGTCAGATCAGGAGTTAAGACGTAACTATGTTCCTCCACCagGTTTCACAATCACTCCACCACCCGGTCCCCCAAACAGGCAAAGCAGTGACTCTGCCTTCTCAAGTAACACTGACTTATCCAGTCAAGTCAAACCATCAACCtcaaatgaaattaatactACACCAGCAAAAAGAAATCGTAAACGCAGTCGTGACAGTGTTGACAATACTTCAGTCAGCAGTCGGTCTCATGACTATGCTCCACCATCTAAACGCGTCACAGAGTTAAGAACATCCCATAAACGACAACGAGCTAATGCTAGCAATAACTCATTTTTGGATTCTGATTTTGATGACAACAGTATATCTCAATTTTCGGCTGCGGAAACGGATTCCGACGAACCATTACTTAAAAAAGAGTACAAATGCACAGAATGTGACAAAACATTTCAAAGTAGAAAGAGCCTTGCGTTACACATGAGAGTCCATTCCGCCAAAAACGACAAAGTATTTGAAAACACGCCTAATGTTTCGAAGACTGTCACAAAAGATGCAAATGACGATGTTGACAAATTGAGCTGTGATAAATGTGGAAAaactttcaaattaaaaattatgttgaatagGCACCACGAGGTGTGTGGCAAAACTCCGCAAATATCTCCCCGAAAAGAGCTTCTCATCTCTTTAGAGCCAATCGACGCTATTTCCCCAAAAAGATTCGACTGTGAAATGTGCACAACTAAATTCAAAACACTAGATAATCTCAAGAAACACATGAGAATTGTTCATGCAGCTAGCCTTAAACAGGACAAGTTTGAAAATAAATCGGTAACTGGAAAAGTTCCAGTGCCctgtttatattgtaaaaaaccTTTCGATGACTACTATGTGCACAGCGCTCACTTCAGCATTTGTCCTGAAAAGATAGAAAGAGCTATGTTTGAATGTACAGTGTGCCAAAAGATGACATACAAGAAGAGTGCTTATTTCTTACATATTAAGAATATGCATTTCGAACCAAGATGTGTTGAAAAGAAACCATTTATGGATGCGAGCGAACCTCGGAATCAGGGGTCGTTTCAGTGCCGAATGTGCAGCAAGCAGCTGGCGTCCCAGGAGCAACTGATCACGCATCTGGCGGCGCATATGTCCAACATCGAGGAGACTGACATAGCAGATGATGACTCTAGGGCAAGCTCAGAGATAGATGTTGAGGACACTGCATCAGTTGTATCTGAATATAGCAACTCGAATGTTACCAGTGGCCCTCTTCAATGCACTCAGTGCGATAAAAAATTCAAGTACAAGAAAGCTCTGGACAACCACGAGCTGAAACATTCACAGTCAAATAGTGGCATAAAGTCGGAACCTCCAGATAAGCATTCCGCAAATCTTTTGCAAGAAACCAGTAGACCAGAGATGGAAACGGAATCTAGTCAAGAAGAAGGGGACGACAACACCTGCGACATTTGTGAAAAGCAGTTCTCTTACAAACGTCTACTTATACACCATAAACGCACTAAACACAACCAATGTTCGGGCACAAAAAGAGCTAAAATCAACCTTAAAGACTGTTTTGTGCGGTGTATGATATGCGATATTGAAATGAAAGTGAGCGCCATCAACGAGCACAATCAAAAACATATATCTGTCAACATGAAACCCAGGAATGTGTACAGTTGCGCTCTGTGTGGTGAGCAGTTCAAGAGTTGTAGCGCCCTTGCCAACCATATAAAGTTTGTGCACCGGCTGAAACAGTCTCCGAAGCAAAAACAGCCGAAAATGCTGCAAGGTGGTTCGGAGTTGGCGGATTTTTGTGAAGTCGTTGTGACGAAGGCGGAACCCCTGGACGTAATCCAGAGTCACAACGACTTTGGTGAGGTTCCGGGCAATGAGGGAGTCATCAATCCTGGCAGCTTCATTTGTCCCATATGCCAGAAGCAGATGCCGACGTTGATATCACTCAAGCGGCATGTCAACTGGCACTCCAATGTTGGCAACAACATACAGAAAAAAGTCGAATGCTTCGTCTGTAAAGAGTCGTTCCGGTTCCAGTGCCACTACAAGCTGCACATGCGCGTGCACTACAACGACACCAACCTGGATCCCAAGTATCTCACGTGCCCCATCTGCAACCGTAAGAGCAAACACCTGCGTGCCGCCCAGGCCCACATGAACTATCACAAGCAAACGCGCTTCAAGAGCAAGGACTACGAGTGCTCTATTTGCAAAAAGATCTTCCAATACCGAAAGGTCTATCTGTCCCACATGGCCATACACTTCAAACGGGGGGAAAGCGTACAAAATACGATAGTCGGCCAAGTGATGCCTAACACGGCGGATAAAACGGTTTACGACGGAACGTTCACCTGCCAATTCTGTGGCAAGGTGTGCGACTCGGAGAACTCCCTGAAGTGCCACGTGAGGTGGCACAACTCCAAGTCCTCGCTGTACGGCGCCAGGCACGAGTGTTCTATATGCGgactggtgttcaccaacaagCGGAGGCTGGAAATTCACAACAGATCCCATTACGAGGACGAGAATGGCCCGTACAAGTGCACCGTCTGCGGCAAAGGGTTCATTGACGAAGACTATTTCCGCAGACACGTCAAAGGCCACAACTTTGATCACCAGTCGCACAAAGACAGAATACAGAAACTGAGGAAGGACAAAGTGAAGTGCCCCATTTGCACACGGTTTTATCCTGACCTgatccacctcatcaggcacttGAGGAGGACTCACCCGGAAAGTAAAATGATTAAAACGGATCCCGACGAACCGCCACCGATTTACTATTCGTGCAAACTTTGTGCGAAAATTTTCATGGACCCGCGGAGGCTGCAGAGCCACGAGGAAGCTCACATGAGGAAGCCTTTGTTCTTTAAATGCAAGTTTTGTGgcaaaaatacaatttcactTAGAAATCATAATGTGCACATCAAAGCTCATTTGACTCGTAATTATTTCGATGAGCCCCTGAAGTGTTCTCAATGTGATGAGATGTTTGTAAAAGGTTACGATTTACACCATCATCTGCGCGATGTGCACAACATCAAAGAGACTTGGATCGCTGAACGAACCGAGCAAACTCTAGAAGGGCCACTGAAAGAATTGCAATGTGCTATATGCCTCAAGGTGTTAGCCAGCAAGGGCAACTTTGAGAGGCACATTGACTACCACAACACTTTGAGATGCAACTATTGCTTCGTTTACTTCAGTACCTTAAGGTTTTTGGAGGGACATTTGGCATTCAGTTGCGACAAGAAGAAATTGATTGGTGATACCGAGATatatactaaaaaaataaaatgtgaacATTGTTATAAAGCATTCCACATGCAAGTAAAACTGGATTGTCATTTGAGGATTAAACATAACATCAAAACGTTTAAAGAGGCATCCTCTGATAAAAAAGAGACTGTCTGCGATTATTGTTTCAGGGTGTTTGAGAATGAAGATGCTTTGTCTACCCATAAAATATACCATCGGACAATTGGTTACTACGGCTGCATTTATTGCAAGCGAAAGTTCAATACATTGACATTatatagaaaacataaaaaCCACCACTTTGCACAGTTGAATGTTGATAACCCATCCAAATGCGAGCACTGTGATGAAACGTTTGTGGCGTTTAGAGAGATGATATACCATATGAGAGATGTTCATGGCGATGACAAAGAGTGGATTGTCATGCCCAAAGACTCGATTGAGGAGACTTGTCCTATTTGCAACAAGACATTCTTCAATCTCCACAAACATTTAGCATATCACGAAGAAAACAGGTGTAAGAAATGTGCCGAGTACTTCTATTCTAGGGCCGATTACGACAACCACCTGTGCGCTATCGAGAGCGACGACGAAGATTTACAAACGAACGGAAACGCTATTCTGCCAGCGTACGAGGAGTGTCGGTTCTGTTTCAAACCAGTCACAAAGTCCAATTCCAAGAAGCTTCACGACAACATCCACCGGACGTCCGGGGCAATATCGTGTCGGTTCTGTTGCCTCAAATTCAAAACGATGGACGCGTTCAACATACACGCGTTCTCGCACAGAAGCAGAAAGTACAACAAGAGGCCGATTAAGTGTCGGAAGTGTAAAGAGAAGTTCGTCAAGTACGGGCCGTTCATGAAGCACATGAAGTACGTGCACAAGTCCAAACTGAAGACGCACTATAGGGCGGTGGTGATGCCGGAGCGGTGCGTGGTGTGCGGCGACGACTTTCCCAACCTGCACAACCACTACCGGGCCCATCTCCAAAACCAGTGCCAGCTCTGCCGCAAGTACTTCACCTCGGCCAAAGTGTTCACTCAGCATCAGTGCGACAAGGAGGACACCGATCCGGCAAAAGTGTTCGTCAGCGATGAAAATCTCACGGCCCTCATCAACTCGTACGTCCCTAAGGACTTGAAGGATGACGAAAAGTTCTACGGTggggcagaagaagaagaagacgacgAGGAGGAGTTGGTTGTCGACGACTTGGATAAGGGACTTGACGTCAAGGACGACGATAGTCAAGCCAGCGAGCACTACATAGAAAATGCGACATCGACGCCGCTCGACAAATTGAGCCAAGACGAAAAAGATTTGCATTTTATGGTGTCATCTCCAATTATATCGGACGTGCTGTCTCTATATCAAAAAAATGAAGACAAGAAGCAAATTGTTGATGACAAAGATGTCGTCACCTTAACAGATGATGACTCTATGGATATTGAAATACCTGTAATCACTATTGATTGA
Protein Sequence
MALKLGKCRLCLKLGDFYSIFTVDNALQLADMVMECARVKVYEGDGLPDKICSECIQKLSSAYIFKQQCERSDQELRRNYVPPPGFTITPPPGPPNRQSSDSAFSSNTDLSSQVKPSTSNEINTTPAKRNRKRSRDSVDNTSVSSRSHDYAPPSKRVTELRTSHKRQRANASNNSFLDSDFDDNSISQFSAAETDSDEPLLKKEYKCTECDKTFQSRKSLALHMRVHSAKNDKVFENTPNVSKTVTKDANDDVDKLSCDKCGKTFKLKIMLNRHHEVCGKTPQISPRKELLISLEPIDAISPKRFDCEMCTTKFKTLDNLKKHMRIVHAASLKQDKFENKSVTGKVPVPCLYCKKPFDDYYVHSAHFSICPEKIERAMFECTVCQKMTYKKSAYFLHIKNMHFEPRCVEKKPFMDASEPRNQGSFQCRMCSKQLASQEQLITHLAAHMSNIEETDIADDDSRASSEIDVEDTASVVSEYSNSNVTSGPLQCTQCDKKFKYKKALDNHELKHSQSNSGIKSEPPDKHSANLLQETSRPEMETESSQEEGDDNTCDICEKQFSYKRLLIHHKRTKHNQCSGTKRAKINLKDCFVRCMICDIEMKVSAINEHNQKHISVNMKPRNVYSCALCGEQFKSCSALANHIKFVHRLKQSPKQKQPKMLQGGSELADFCEVVVTKAEPLDVIQSHNDFGEVPGNEGVINPGSFICPICQKQMPTLISLKRHVNWHSNVGNNIQKKVECFVCKESFRFQCHYKLHMRVHYNDTNLDPKYLTCPICNRKSKHLRAAQAHMNYHKQTRFKSKDYECSICKKIFQYRKVYLSHMAIHFKRGESVQNTIVGQVMPNTADKTVYDGTFTCQFCGKVCDSENSLKCHVRWHNSKSSLYGARHECSICGLVFTNKRRLEIHNRSHYEDENGPYKCTVCGKGFIDEDYFRRHVKGHNFDHQSHKDRIQKLRKDKVKCPICTRFYPDLIHLIRHLRRTHPESKMIKTDPDEPPPIYYSCKLCAKIFMDPRRLQSHEEAHMRKPLFFKCKFCGKNTISLRNHNVHIKAHLTRNYFDEPLKCSQCDEMFVKGYDLHHHLRDVHNIKETWIAERTEQTLEGPLKELQCAICLKVLASKGNFERHIDYHNTLRCNYCFVYFSTLRFLEGHLAFSCDKKKLIGDTEIYTKKIKCEHCYKAFHMQVKLDCHLRIKHNIKTFKEASSDKKETVCDYCFRVFENEDALSTHKIYHRTIGYYGCIYCKRKFNTLTLYRKHKNHHFAQLNVDNPSKCEHCDETFVAFREMIYHMRDVHGDDKEWIVMPKDSIEETCPICNKTFFNLHKHLAYHEENRCKKCAEYFYSRADYDNHLCAIESDDEDLQTNGNAILPAYEECRFCFKPVTKSNSKKLHDNIHRTSGAISCRFCCLKFKTMDAFNIHAFSHRSRKYNKRPIKCRKCKEKFVKYGPFMKHMKYVHKSKLKTHYRAVVMPERCVVCGDDFPNLHNHYRAHLQNQCQLCRKYFTSAKVFTQHQCDKEDTDPAKVFVSDENLTALINSYVPKDLKDDEKFYGGAEEEEDDEEELVVDDLDKGLDVKDDDSQASEHYIENATSTPLDKLSQDEKDLHFMVSSPIISDVLSLYQKNEDKKQIVDDKDVVTLTDDDSMDIEIPVITID

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01081802; iTF_00006459;
90% Identity
-
80% Identity
-