Basic Information

Gene Symbol
-
Assembly
GCA_951230895.1
Location
OX579653.1:474335-474880[+]

Transcription Factor Domain

TF Family
HMGA
Domain
HMGA domain
PFAM
AnimalTFDB
TF Group
Unclassified Structure
Description
This entry represents the HMGA family, whose members contain DNA-binding domains, also known as AT hooks due to their ability to interact with the narrow minor groove of AT-rich DNA sequences. They play an important role in chromatin organisation [1]. The high mobility group (HMG) proteins are the most abundant and ubiquitous nonhistone chromosomal proteins. They bind to DNA and to nucleosomes and are involved in the regulation of DNA-dependent processes such as transcription, replication, recombination, and DNA repair. They can be grouped into three families: HMGB (HMG 1/2), HMGN (HMG 14/17) and HMGA (HMG I/Y). The characteristic domains are: AT-hook for the HMGA family, the HMG Box for the HMGB family, and the nucleosome-binding domain (NBD) for the members of the HMGN family [2].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 10 0.0018 32 5.3 0.0 4 12 7 15 4 16 0.89
2 10 0.35 6.3e+03 -2.1 0.0 5 10 26 31 23 33 0.78
3 10 0.0018 32 5.3 0.0 4 12 43 51 40 52 0.89
4 10 0.0018 32 5.3 0.0 4 12 61 69 58 70 0.89
5 10 0.0018 32 5.3 0.0 4 12 79 87 76 88 0.89
6 10 0.35 6.3e+03 -2.1 0.0 5 10 98 103 95 105 0.78
7 10 0.0018 32 5.3 0.0 4 12 115 123 112 124 0.89
8 10 0.35 6.3e+03 -2.1 0.0 5 10 134 139 131 141 0.78
9 10 0.0018 32 5.3 0.0 4 12 151 159 148 160 0.89
10 10 0.23 4.2e+03 -1.5 0.0 5 12 170 177 167 177 0.81

Sequence Information

Coding Sequence
atgccgcgccacaGCGCCGCCGTCCCGGCCCCGGCCCGCCCCCGgtacggcgctatgccgcgccacaGCGCCGCCGTCCCGGCCCCGGCCCGCCTCCGgtacggcgctatgccgcgccacaGCGCCGCCGTCCCGGCCCCGGCCCGCCCCCGgtacggcgctatgccgcgccacaGCGCCGCCGTCCCGGCCCCGGCCCGCCCCCGgtacggcgctatgccgcgccacaGCGCCGCCGTCCCGGCCCCGGCCCGCCCCCGgtacggcgctatgccgcgccacaGCGCCGCCGTCCCGGCCCCGGCCCGCCTCCGgtacggcgctatgccgcgccacaGCGCCGCCGTCCCGGCCCCGGCCCGCCCCCGgtacggcgctatgccgcgccacaGCGCCGCCGTCCCGGCCCCGGCCCGCCTCCGgtacggcgctatgccgcgccacaGCGCCGCCGTCCCGGCCCCGGCCCGCCCCCGgtacggcgctatgccgcgccacaGCGCCGCCGTCCCGGCCCCGGCCTGCCCCCGgtacggctctgtgtga
Protein Sequence
MPRHSAAVPAPARPRYGAMPRHSAAVPAPARLRYGAMPRHSAAVPAPARPRYGAMPRHSAAVPAPARPRYGAMPRHSAAVPAPARPRYGAMPRHSAAVPAPARLRYGAMPRHSAAVPAPARPRYGAMPRHSAAVPAPARLRYGAMPRHSAAVPAPARPRYGAMPRHSAAVPAPACPRYGSV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-