Ckad005243.1
Basic Information
- Insect
- Caradrina kadenii
- Gene Symbol
- topi
- Assembly
- GCA_947462355.1
- Location
- OX381686.1:12968598-12974045[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 12 0.0022 0.13 12.9 0.8 1 23 268 290 268 290 0.98 2 12 0.0056 0.32 11.6 2.1 2 23 298 319 297 319 0.94 3 12 0.073 4.2 8.1 0.1 1 23 323 345 323 345 0.94 4 12 7.2e-05 0.0042 17.5 0.6 1 23 350 373 350 373 0.98 5 12 0.00048 0.028 14.9 0.3 1 23 377 400 377 400 0.94 6 12 0.0048 0.28 11.8 0.2 2 20 416 434 416 440 0.93 7 12 0.00082 0.047 14.2 0.6 3 23 449 469 449 469 0.98 8 12 0.073 4.2 8.1 1.3 2 23 491 513 491 513 0.97 9 12 5.1e-05 0.0029 18.0 0.3 1 23 524 546 524 546 0.98 10 12 1.8e-05 0.001 19.4 3.5 1 23 552 574 552 574 0.99 11 12 0.00064 0.037 14.5 1.0 1 23 580 602 580 602 0.98 12 12 7.7e-06 0.00045 20.6 1.0 1 23 608 631 608 631 0.98
Sequence Information
- Coding Sequence
- ATGGAACTCATGAAAGTGTGTCGTATTTGCTTAATAGTTGACGTAAAATTACACGATCTGAGATCGTACCCATTAGAATGTTATTATGAGTCTGTAATAGGAACCAATCCCGAGTACGCCACCTTGCCTCCATTTGCCTGTTTTGAATGTGCAGCACTTGTGAAGAAGTTTTATTTCTTTAGACAGAAATGTCTGCGGAGCCATGCTGTATTGTTTGGCACTATAGATGACTATGGCAAGCTAAAATCTAGTGAAATAAGATTAATAAACAGAAAAGATCTCCACATCATCTCAAACCTCAACATCACCACTCTGCCAAACTTGGAAATATGTGAACAAAATAAAACTCAAATAAAGAAAAAAGTAAAACGTGAACCGAATGACAAAATACAAAATAATAATGAAAATAAGTATTTTATTGGAGATCATAATTATGCTACCTCATTGATGGATCCCAGTGGTAATAAACTTACTTCGGTTGACACGGAGATGCATAGTGAAAATAAAGAGTCACAAAAAGAGATGGTGGTCTTGAAAGAAACTAGTCATGAGTTTCCCGAAAGGGAAGAAGACTTGGAACATACAATTGAAGTACCAGAAGTGATAGAGAAGATGGAGAAACGAAAGCCATGTCAACTGAGAATAAAAAGAAAGCATAAAAAAGAGTTGTTGAACCCAAATATGGCTGCTCAGTGCAATAGTGATTTTGCACAATACATCGCTGTTATTACTTTGTCGCTGGAAGAGCAGAAAGAAGAGATAGAGAAACGGAAACAGTCGTCCAACTACTTGTATGCAACATTCCAGTGTAATCTGTGCTATAAAGGGTTCGTTGATAATGATGCCTGGGATCATCATGTCAGTAAACATTCTGAGAGCGCAGGCAGCATAGAATGTGAAGTATGTAAATTGAGATTTAAAACAAAGCATGCCTATTATAAACATGCATCCAATCACGAGAAAAAATACGTCTGTAAATTATGTCCATACGTATCGACTAGCATGGCTCAAGCAAAGCAGCACCAAGGGTGGCATAAAGGAATTACTTACAAGTGTAAATTTTGTGACGAAGTCTTTATTATGTGGACGTCGTACATGGGCCACATGCGAATCAAACACCCGTCAGAGTTCATATGCAGTTACTGCGGGTACTCATTCGTCAGCAAGTTGGGCCTCGCCATGCACAAGACGATGATGCACAAAGATGTTCAAGGGAAAACAGAAGGAAACACAGAGGAAGGTCCATATTGCGAAGAGTGTGATGTCAAATTCATATCGACTGAAGCTTACAAGAGACACATGGTCATGTCTGTCAAGCACACACAGAGTACAGAAATTAAAGGCTGTCGGACCTGTGGCGCGACTTTCGAGAATCCAGATGAATTTCGGCAGCATCGTAAGGAGCATGCGCGGTTGAGACCCAAGAACTACGGGAAAAAACCTAATCCTAACATCGGTAAATGGCCTGCTAAATGCGAACACTGTCCCGAGGAGTTCCTCAATGCCTTCGAGTATAGGTCGCACTTCCGGCGAGCGCATCCCGACAAGAAGTACCCCGTGCAGAAGAACTATATGTGCGATATATGCGGCAAGAGTTTTGGGGCAAACGCATTCCTAGTGTACCACAGACGCACGCATTTCGAAGACCGCCCGTATAAATGTTCGCAGTGCGACAAGGCTTTCTTTAACCGCCACAACTTGGTCTTACATGAGAAAACTCACTCGGATAACAGGCCGTACCCATGCGCCGTCTGTTCCAAAGCTTTCAAGTGTAAGGGAGCGCTTAAAAGACATGTTCAAAGCCACACAGGTCAAAAACCCTACGAGTGTGAAGTATGCGGCAAAAAATTCACTCAGACAAGTAGCAAGAAACTTCACGTACGCACGGTACATATGAAGCAACCCGCGCCCCGTCGCAACCGCCTTAAGAGAAGGACTACAGAACCGCTTACACAGCAGTTTATATACTAG
- Protein Sequence
- MELMKVCRICLIVDVKLHDLRSYPLECYYESVIGTNPEYATLPPFACFECAALVKKFYFFRQKCLRSHAVLFGTIDDYGKLKSSEIRLINRKDLHIISNLNITTLPNLEICEQNKTQIKKKVKREPNDKIQNNNENKYFIGDHNYATSLMDPSGNKLTSVDTEMHSENKESQKEMVVLKETSHEFPEREEDLEHTIEVPEVIEKMEKRKPCQLRIKRKHKKELLNPNMAAQCNSDFAQYIAVITLSLEEQKEEIEKRKQSSNYLYATFQCNLCYKGFVDNDAWDHHVSKHSESAGSIECEVCKLRFKTKHAYYKHASNHEKKYVCKLCPYVSTSMAQAKQHQGWHKGITYKCKFCDEVFIMWTSYMGHMRIKHPSEFICSYCGYSFVSKLGLAMHKTMMHKDVQGKTEGNTEEGPYCEECDVKFISTEAYKRHMVMSVKHTQSTEIKGCRTCGATFENPDEFRQHRKEHARLRPKNYGKKPNPNIGKWPAKCEHCPEEFLNAFEYRSHFRRAHPDKKYPVQKNYMCDICGKSFGANAFLVYHRRTHFEDRPYKCSQCDKAFFNRHNLVLHEKTHSDNRPYPCAVCSKAFKCKGALKRHVQSHTGQKPYECEVCGKKFTQTSSKKLHVRTVHMKQPAPRRNRLKRRTTEPLTQQFIY
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00273836; iTF_00810330; iTF_00809400;
- 90% Identity
- -
- 80% Identity
- -