Ccla011211.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Caradrina clavipalpis
Gene Symbol
lola
Assembly
GCA_932526535.1
Location
OW052102.1:653598-660728[+]

Transcription Factor Domain

TF Family
BTB
Domain
zf-C2H2|ZBTB
PFAM
PF00651
TF Group
Zinc-Coordinating Group
Description
The BTB (for BR-C, ttk and bab) [6] or POZ (for Pox virus and Zinc finger) [1] domain is present near the N-terminus of a fraction of zinc finger (Pfam:PF00096) proteins and in proteins that contain the Pfam:PF01344 motif such as Kelch and a family of pox virus proteins. The BTB/POZ domain mediates homomeric dimerisation and in some instances heteromeric dimerisation [1]. The structure of the dimerised PLZF BTB/POZ domain has been solved and consists of a tightly intertwined homodimer. The central scaffolding of the protein is made up of a cluster of alpha-helices flanked by short beta-sheets at both the top and bottom of the molecule [2]. POZ domains from several zinc finger proteins have been shown to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes including N-CoR and SMRT [5, 3, 4]. The POZ or BTB domain is also known as BR-C/Ttk or ZiN.
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 1 2.9e-30 8.1e-28 97.0 0.1 1 100 22 117 22 121 0.94

Sequence Information

Coding Sequence
ATGGACGACGACCAACAGTTCTGCCTGAGGTGGAACAACCATCAGTCGACACTGGTGTCTGTTTTTGACACTCTTCTCGAGAAGGGTATGCACGTGGACTGCACCCTGGCTGCAGAGGGACAGACGCTCAAGGCGCACAAAGTGGTCCTATCGGCATGCAGTCCCTATTTCGAGAGTGTATTATCTCAGCAGTATGATAAGCATCCAATAATCATCCTCAAAGATGTGAAATATGCTGAGTTGAGAGCGATGATGGATTATATGTATCGCGGTGAGGTCAACATATCTCAAGACCAGTTGGCCGCACTGCTGAAAGCCGCAGAGTCCCTACAGATCAAGGGTCTCTCTGACAATAAGCCTTCGAGGCCACCGTCGCGCCCTGCGCAGGCTGTAGCTGCACACCCGCCTCGTGCCCCCTCACCACCTCCTCAGGTCCGAGACGGTAGTATAGACAGCAGCCGCGAAGGGTCAGTGAGCCCAACACGGCGTCGGAAGAAAGCGCGTCGCATGTCCAGTGAGTTGCCGCCCGTACCTATCCCGCCGCCCAACGACAACGCGCAAGGCAATGGAGACGACGCCTCATGCAAGGAGGAGCTGCAGAGGGACGGCGTCGAGGACCTCACGCTCGACGAAGAAGCCGACGACCAGCCCGTTGTGGCGCACAATGATGTTGTACGCAATTTCCAATGGCACATGGAACGATCTCAAGATGATATTATGAACTCGAGTGACGGCGCGCGAGAGTCGCAAGAGTTGCACAAGGATAGCCACCTGCCGTCGGCACTGCTGTCGCTGCTGTCGGTTCAGCAGGCGCAGTCGCAGTCGCTGGTGTCGCTGGTGCCGTCCTGCATCCAACTCACTAATATCATGAAGCCCTCCGCCACTAAAGACCTCGTGCCCTATTCTTCGCACTTGCCCAAGCTGCCGCTAGACACGCTCAACTCCATTCCGGAGAACATTAAGGCGCATCTCTTGCAGCAAGCGTTTATGCAGAACAATAACACGGTGGCACAGAGCATGGAGTACAAGCTGCCCATCAAGCAGGACGACACGGAGTCGGACGCGGAGTACGACGACACCGACGACATCGTGCTGCCGGAGGAGGCCGACACCTTCTACGACAGCAGCGGCGGCTTCCCGGGCAACTCGGGCGACGACGCGTACGACACCAAGCCCGACATGAAGGGGCACTGGAAGCGCGACGGCAACAGCTCGGACGACGCCAGCCGCCAGTTCGAGTGCAAGCACTGCGGTAAGAAGTACCGCTGGAAGTCCACCCTGCGCCGCCACGAGAACGTGGAGTGCGGCGGGAAGGCGCCATCCCACCAATGCCCCTACTGCTCCTACAAGGCCAAGCAGCGGGGCAACCTAGGCGTACACATTAGGAAGCACCACAACAACGAGTGGTACATATACGCTAGCAACAAAGTTAGGCGGAATAAAAAAACGTCTATTTAG
Protein Sequence
MDDDQQFCLRWNNHQSTLVSVFDTLLEKGMHVDCTLAAEGQTLKAHKVVLSACSPYFESVLSQQYDKHPIIILKDVKYAELRAMMDYMYRGEVNISQDQLAALLKAAESLQIKGLSDNKPSRPPSRPAQAVAAHPPRAPSPPPQVRDGSIDSSREGSVSPTRRRKKARRMSSELPPVPIPPPNDNAQGNGDDASCKEELQRDGVEDLTLDEEADDQPVVAHNDVVRNFQWHMERSQDDIMNSSDGARESQELHKDSHLPSALLSLLSVQQAQSQSLVSLVPSCIQLTNIMKPSATKDLVPYSSHLPKLPLDTLNSIPENIKAHLLQQAFMQNNNTVAQSMEYKLPIKQDDTESDAEYDDTDDIVLPEEADTFYDSSGGFPGNSGDDAYDTKPDMKGHWKRDGNSSDDASRQFECKHCGKKYRWKSTLRRHENVECGGKAPSHQCPYCSYKAKQRGNLGVHIRKHHNNEWYIYASNKVRRNKKTSI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01527459; iTF_00173196; iTF_01440207; iTF_00831355; iTF_00364160; iTF_00784515; iTF_00018281; iTF_01285675; iTF_00786106; iTF_00425572; iTF_01247237; iTF_01532229; iTF_01061996; iTF_01064784; iTF_00928825; iTF_01063870; iTF_01533189; iTF_01535047; iTF_01062946; iTF_00120649; iTF_00446345; iTF_00447374; iTF_00445329; iTF_01534072; iTF_00000445; iTF_00001284; iTF_01152291; iTF_01502212; iTF_00432357; iTF_00809286; iTF_01425224; iTF_01377613; iTF_00383822; iTF_00017457; iTF_01441218; iTF_00908039; iTF_00622957; iTF_00449294; iTF_00726578; iTF_00037939; iTF_01526196; iTF_00906293; iTF_00038966; iTF_00907158; iTF_01119494; iTF_00111783; iTF_01118449; iTF_00043689; iTF_00772137; iTF_00851939; iTF_00300365; iTF_00952816; iTF_00850898; iTF_00951955; iTF_00040010; iTF_01085515; iTF_01192838; iTF_01084392; iTF_00685580; iTF_00375437; iTF_01093250; iTF_01095074; iTF_00924899; iTF_00122535; iTF_00121577; iTF_00123499; iTF_00667662; iTF_00124404; iTF_00758388; iTF_00147641; iTF_00237882; iTF_01094171; iTF_00745916; iTF_00071616; iTF_00973901; iTF_01026450; iTF_00888392; iTF_01027465; iTF_01029387; iTF_01031246; iTF_01028435; iTF_01030361; iTF_01230751; iTF_00177299; iTF_00302259; iTF_00301320; iTF_00036950; iTF_00041016; iTF_00171961; iTF_00041918; iTF_01117470; iTF_00008138; iTF_01546758; iTF_01544053; iTF_01543069; iTF_01544989; iTF_01545856; iTF_00823146; iTF_00450283; iTF_01260240; iTF_00441644; iTF_00823993; iTF_01339052; iTF_01437196; iTF_01487821; iTF_00712047; iTF_00637809; iTF_00405127; iTF_00677777; iTF_00869781; iTF_00794784; iTF_00810228; iTF_00274535; iTF_00806837; iTF_01073717; iTF_00622097; iTF_01173397; iTF_00889366; iTF_00186393; iTF_00785314; iTF_00327182; iTF_00185433; iTF_01222111; iTF_01221716; iTF_01180409; iTF_01179587; iTF_01342329; iTF_00281498; iTF_00282543; iTF_01362523; iTF_01363231; iTF_00761799; iTF_00072383; iTF_00072206; iTF_01504000;
90% Identity
iTF_00809286; iTF_00274535; iTF_00810228; iTF_01062946; iTF_01532229; iTF_01533189; iTF_01535047; iTF_00301320; iTF_01084392; iTF_00043689; iTF_00040010; iTF_01085515; iTF_00685580; iTF_01061996; iTF_00712047; iTF_01064784; iTF_00302259; iTF_01534072; iTF_00928825; iTF_00041918; iTF_01063870; iTF_00924899; iTF_01119494; iTF_00111783; iTF_01118449; iTF_01028435; iTF_01027465; iTF_01030361; iTF_01117470; iTF_01230751; iTF_01093250; iTF_01095074; iTF_00122535; iTF_00121577; iTF_00123499; iTF_00667662; iTF_00124404; iTF_00758388; iTF_01094171; iTF_00071616; iTF_00784515; iTF_00785314; iTF_00851939; iTF_01247237; iTF_01192838; iTF_01441218; iTF_00908039; iTF_00449294; iTF_00726578; iTF_00037939; iTF_00906293; iTF_00038966; iTF_00907158; iTF_00888392; iTF_01029387; iTF_01031246; iTF_01026450; iTF_00036950; iTF_00147641; iTF_00237882; iTF_00446345; iTF_00447374; iTF_00445329; iTF_00772137; iTF_00173196; iTF_00300365; iTF_00973901; iTF_00425572; iTF_00120649; iTF_00375437; iTF_00745916; iTF_00364160; iTF_01440207; iTF_01339052; iTF_00177299; iTF_00952816; iTF_00850898; iTF_00951955; iTF_00041016; iTF_00171961; iTF_01342329; iTF_00831355; iTF_01527459; iTF_00622957; iTF_01526196; iTF_00072383; iTF_00072206;
80% Identity
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