Basic Information

Transcription Factor Domain

TF Family: zf-GAGA
Domain: zf-GAGA domain
PFAM: PF09237
TF Group: Zinc-Coordinating Group
Description: Members of this family bind to a 5'-GAGAG-3' DNA consensus binding site, and contain a Cys2-His2 zinc finger core as well as an N-terminal extension containing two highly basic regions. The zinc finger core binds in the DNA major groove and recognises the first three GAG bases of the consensus in a manner similar to that seen in other classical zinc finger-DNA complexes. The second basic region forms a helix that interacts in the major groove recognising the last G of the consensus, while the first basic region wraps around the DNA in the minor groove and recognises the A in the fourth position of the consensus sequence [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 8 0.14 3.1e+02 2.4 0.0 21 47 90 116 83 123 0.82

2 8 0.12 2.6e+02 2.7 0.0 26 51 124 149 118 151 0.85

3 8 0.24 5.2e+02 1.7 0.1 21 45 147 171 144 179 0.85

4 8 0.034 73 4.4 0.4 21 45 175 199 167 206 0.79

5 8 0.011 24 6.0 0.1 20 47 202 229 195 234 0.80

6 8 0.037 81 4.3 0.0 21 47 231 257 228 262 0.82

7 8 0.0015 3.2 8.8 0.1 21 45 259 283 255 292 0.83

8 8 0.0072 16 6.6 0.1 22 48 316 342 312 344 0.88

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	8	0.14	3.1e+02	2.4	0.0	21	47	90	116	83	123	0.82
2	8	0.12	2.6e+02	2.7	0.0	26	51	124	149	118	151	0.85
3	8	0.24	5.2e+02	1.7	0.1	21	45	147	171	144	179	0.85
4	8	0.034	73	4.4	0.4	21	45	175	199	167	206	0.79
5	8	0.011	24	6.0	0.1	20	47	202	229	195	234	0.80
6	8	0.037	81	4.3	0.0	21	47	231	257	228	262	0.82
7	8	0.0015	3.2	8.8	0.1	21	45	259	283	255	292	0.83
8	8	0.0072	16	6.6	0.1	22	48	316	342	312	344	0.88

Coding Sequence: ATGTCCGAAATAACTGAAATGAATTTGAATGTTAACAATGAACTGGATGCTGCTATTAAGGAAGAACCAGTGGAGACTTGCAGTGATGAAAATATCGAACATGTGCATGATACGTTGGAAGCTATAAAACAGAACACAATCTACATTTGCAATATCAAACAAGAAACTACCGACTACAGATCTGAAAACTCTGACAATAACGAGGAAGAAACAGAAGGGTCAGGATTTCGTTCCGACGAAATTAAAATATCTGAAAGTGACACACACAACGATAAAAGATTTACATGTTCGGTGTGTAACATgaaatttaaatggaaaaataatttgatgAGTCACATGAAAGTTCACAATTCTAACAAAAGGGACTTTGTTTGCACCACGTGTAATGCAAGTTTCAGGTGGAAGAATAACTTGGTAAGTCATGTAAAAATTCATACTGACGAAAAGCCATATGCTTGCGAAGTGTGCGACAGTAAGTTCACAACTCAACGATATCTACACAGTCACAAACAAATTCACGCCTCGAAGAAACGACACATATGTCCGATTTGCAACGCTCAATACGCCTGGAAAGTGAGCTTGGATAGGCACATAAGATCtcacaccggcgaaaaaccattttcttgtaaaatttgtCATATCAAATTTGCGGGTAGAAGCAATCTACATACTCACATGACGGTTCATTCCGACGAAAAACCGTTTGCAtgcaaaatttgtaactttaaattttcGCGAAAGTATAACTTAAACAGTCACATGAAGACGCACAATAAAGAAAAACCTTATTCGTGTGAAATTTGTCAAGCCAAGTTTGCGGGGAAAAGCAGTTTAAGGAGGCACGAAAAATCCCATTCCGGTGAAAAGCCCTACGTATGTGATCAGTGCGACTCGAAATTTACGCGAAAGTATATTTTAGATAGTCACATGCTGACTCACACACACGACAAACCTTTTGGTTGCGATAAGTGTAATGCTAGATTTGTGTGGAAGAGAAGTTTAAGAAGGCACATTCAAACTATACACGAAGAGAATAACTAG
Protein Sequence: MSEITEMNLNVNNELDAAIKEEPVETCSDENIEHVHDTLEAIKQNTIYICNIKQETTDYRSENSDNNEEETEGSGFRSDEIKISESDTHNDKRFTCSVCNMKFKWKNNLMSHMKVHNSNKRDFVCTTCNASFRWKNNLVSHVKIHTDEKPYACEVCDSKFTTQRYLHSHKQIHASKKRHICPICNAQYAWKVSLDRHIRSHTGEKPFSCKICHIKFAGRSNLHTHMTVHSDEKPFACKICNFKFSRKYNLNSHMKTHNKEKPYSCEICQAKFAGKSSLRRHEKSHSGEKPYVCDQCDSKFTRKYILDSHMLTHTHDKPFGCDKCNARFVWKRSLRRHIQTIHEENN

Sequence clustering based on sequence similarity using MMseqs2