Basic Information

Insect: Cantharis nigra
Gene Symbol: -
Assembly: GCA_958510845.1
Location: OY294029.1:43214875-43216722[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 18 0.00098 0.051 14.9 4.1 2 23 83 104 83 104 0.97

2 18 0.0045 0.23 12.8 2.0 1 23 110 132 110 132 0.97

3 18 5.9e-05 0.0031 18.7 0.5 1 23 138 160 138 160 0.98

4 18 0.03 1.6 10.2 2.4 1 23 166 189 166 189 0.94

5 18 0.00074 0.039 15.3 4.3 1 23 212 234 212 234 0.98

6 18 0.015 0.77 11.2 2.1 1 23 240 263 240 263 0.97

7 18 0.072 3.7 9.0 10.6 1 23 269 291 269 291 0.97

8 18 0.0025 0.13 13.6 1.6 3 23 299 319 297 319 0.96

9 18 2.9e-06 0.00015 22.8 0.7 1 23 325 347 325 347 0.98

10 18 0.0025 0.13 13.6 3.6 3 23 355 375 353 375 0.98

11 18 1.3e-05 0.00069 20.8 1.0 3 23 383 403 381 403 0.98

12 18 0.015 0.8 11.1 3.8 3 23 411 431 409 431 0.98

13 18 0.00019 0.0099 17.1 2.0 1 23 437 459 437 459 0.98

14 18 0.0046 0.24 12.8 2.0 3 23 469 489 467 489 0.98

15 18 9e-05 0.0047 18.1 2.3 1 23 495 517 495 517 0.98

16 18 0.017 0.91 10.9 2.4 1 23 523 546 523 546 0.96

17 18 0.024 1.3 10.5 0.2 1 23 552 574 552 574 0.97

18 18 0.00082 0.043 15.1 3.3 1 23 580 603 580 603 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	18	0.00098	0.051	14.9	4.1	2	23	83	104	83	104	0.97
2	18	0.0045	0.23	12.8	2.0	1	23	110	132	110	132	0.97
3	18	5.9e-05	0.0031	18.7	0.5	1	23	138	160	138	160	0.98
4	18	0.03	1.6	10.2	2.4	1	23	166	189	166	189	0.94
5	18	0.00074	0.039	15.3	4.3	1	23	212	234	212	234	0.98
6	18	0.015	0.77	11.2	2.1	1	23	240	263	240	263	0.97
7	18	0.072	3.7	9.0	10.6	1	23	269	291	269	291	0.97
8	18	0.0025	0.13	13.6	1.6	3	23	299	319	297	319	0.96
9	18	2.9e-06	0.00015	22.8	0.7	1	23	325	347	325	347	0.98
10	18	0.0025	0.13	13.6	3.6	3	23	355	375	353	375	0.98
11	18	1.3e-05	0.00069	20.8	1.0	3	23	383	403	381	403	0.98
12	18	0.015	0.8	11.1	3.8	3	23	411	431	409	431	0.98
13	18	0.00019	0.0099	17.1	2.0	1	23	437	459	437	459	0.98
14	18	0.0046	0.24	12.8	2.0	3	23	469	489	467	489	0.98
15	18	9e-05	0.0047	18.1	2.3	1	23	495	517	495	517	0.98
16	18	0.017	0.91	10.9	2.4	1	23	523	546	523	546	0.96
17	18	0.024	1.3	10.5	0.2	1	23	552	574	552	574	0.97
18	18	0.00082	0.043	15.1	3.3	1	23	580	603	580	603	0.97

Sequence Information

Coding Sequence: ATGGATCAAAAACCAATATTGGAAGAGTTTCAATATCTTGAAGAAAGAAAtgaagttttgttaaaaattaagaaagaagAGCCAGatgatacaaaatttaatttggacgATTTGCATCATTCAATTGATATCAAAGAAGAGAACCTATGGCTGGAATCTCGAATAGACCAAGAACGCGATTTACAAAGTAAACCAAATTTTGATAGTAAACTGCATTCCAACATAAACTGTCTTCTAAAACCGAGAGTATGTCGAAAATGTAACTACAAATGTTCAGACAAAAGTGATTTGAAACTGCATGTGAAAACTCATACACCGGAGAAACTGTTtaaatgtgaaatttgtgaataTAAAAGTTTAACCAAACATCAGTTGCTGGTGCATATGCGAATTCATACCGGAGAGAAACCCTACGTTTGTACAATTTGTGACTTGAAGTTTTCACAAAGAGGAGGTTTGtcaaatcattttaaaattcacaccggggaaaaacctTTTTTGTGCGCATTATGTGACTATAAATGCGCACATAAAGGAGGACTGAAAATGCACATTTTGAGAAATCATACTGAAAATAAACCGTTTGCGTTTGAAATTAAACAAGAATCGGCATTGCATAACGACCATATCCGATATGCATGTGAAATATGCGACTATAAATGTGTATACAAATGTAGTTTGAAACAGCATATGataactcataccggcgaaaagccgtttGAATGTGCGGTTTGTGCCTTCAAATGCTCATTCAAACGTAATTTGAAGCTGCATATGTTGTCCGTTCACTCTACCGAGAAACCATTCATGTGTACGTGTTGTAAATACAGATGTTCGACCAAGAAATATTTGAAACGACATATGAAGACCCATACAGGTTTGAAATCTATTGCTTGTGAAATGTGCGACTATAAATGTTTGGATAAAACTTATTTGACTCGGCATATGAGAattcatacgggcgagaaactATTCGTATGTACTATTTGTGATCGTAAAATTTCAACCAAACAACAGTTGGAAATTCATATGAGAACTCACTCCGGAGAGAAACCGTTTGGATGTAAACTTTGTGATCATAAGACTTCAAACAAACGTCAGTTGTTATTGCATATGAGAAGTCATACAGGAGAAAAACCATTTGGGTGCAACATATGCACTTACAAATTTTCAACCAAGCAACAGTTGGTAAAACATATGATGATCCACACCGGAGATAAACCGTTTGGATGTCAAGTTTGCGATCATAAGTCTTCAACCAAGTATCACTTGTTATTGCATATAACAACCCATACCGGTGAAAAACGGTTTGTGTGTAACGTTTGCGATCATAAATTGTCAACCAAACAGCAGTTGGTAGCTCATAAGAGAACTCACATCGGAGACATCTCGAAACCTTTCGGTTGCAAATTTTGTGATAGTAGATCTACAaccaaatataaattgaatttacatATGAGAATTCACACCGGAGAGAAACCCTATGCATGTCAAATTTGTGACTTCAAATGTTCGCGAAAAGACAGTTTGAAGAACCATGTTATAACACACACCGGAGAGAAACCTTTTATGTGTGCATTATGTAACTATAAATGTGCATTCAAAgacaaactaaaaattcatattttgagAAATCATACCGAAAATAAACCGTTTGCATGTGAAATGTGCGATTATAAAGGTGCAATCGAATATGCTTTCAAACGGCATGTGAGAACTCATTCGGGAGAAAAGCCATTCGAGTGTGAAGTTTGCTACAACAGGTATTCACGCAAGTACCATTTGGAACagcatattttgaaaaaacatcCTGATGAAAATCTGGTTGTTCTCAAAAAGGACATTTAA
Protein Sequence: MDQKPILEEFQYLEERNEVLLKIKKEEPDDTKFNLDDLHHSIDIKEENLWLESRIDQERDLQSKPNFDSKLHSNINCLLKPRVCRKCNYKCSDKSDLKLHVKTHTPEKLFKCEICEYKSLTKHQLLVHMRIHTGEKPYVCTICDLKFSQRGGLSNHFKIHTGEKPFLCALCDYKCAHKGGLKMHILRNHTENKPFAFEIKQESALHNDHIRYACEICDYKCVYKCSLKQHMITHTGEKPFECAVCAFKCSFKRNLKLHMLSVHSTEKPFMCTCCKYRCSTKKYLKRHMKTHTGLKSIACEMCDYKCLDKTYLTRHMRIHTGEKLFVCTICDRKISTKQQLEIHMRTHSGEKPFGCKLCDHKTSNKRQLLLHMRSHTGEKPFGCNICTYKFSTKQQLVKHMMIHTGDKPFGCQVCDHKSSTKYHLLLHITTHTGEKRFVCNVCDHKLSTKQQLVAHKRTHIGDISKPFGCKFCDSRSTTKYKLNLHMRIHTGEKPYACQICDFKCSRKDSLKNHVITHTGEKPFMCALCNYKCAFKDKLKIHILRNHTENKPFACEMCDYKGAIEYAFKRHVRTHSGEKPFECEVCYNRYSRKYHLEQHILKKHPDENLVVLKKDI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00268836; iTF_00270187;
90% Identity: iTF_00268836;
80% Identity: -