Basic Information

Transcription Factor Domain

TF Family: zf-GAGA
Domain: zf-GAGA domain
PFAM: PF09237
TF Group: Zinc-Coordinating Group
Description: Members of this family bind to a 5'-GAGAG-3' DNA consensus binding site, and contain a Cys2-His2 zinc finger core as well as an N-terminal extension containing two highly basic regions. The zinc finger core binds in the DNA major groove and recognises the first three GAG bases of the consensus in a manner similar to that seen in other classical zinc finger-DNA complexes. The second basic region forms a helix that interacts in the major groove recognising the last G of the consensus, while the first basic region wraps around the DNA in the minor groove and recognises the A in the fourth position of the consensus sequence [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 7 0.0016 2.3 9.2 0.2 13 45 60 92 57 98 0.93

2 7 0.0035 4.9 8.1 0.3 21 52 148 179 143 181 0.88

3 7 0.87 1.2e+03 0.4 0.0 21 43 176 198 174 202 0.78

4 7 0.068 97 4.0 0.0 21 45 204 228 195 232 0.88

5 7 0.00038 0.54 11.2 0.0 21 47 232 258 228 264 0.87

6 7 0.047 67 4.5 0.0 21 52 260 291 256 292 0.77

7 7 0.16 2.3e+02 2.8 0.2 21 45 288 312 284 316 0.81

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	7	0.0016	2.3	9.2	0.2	13	45	60	92	57	98	0.93
2	7	0.0035	4.9	8.1	0.3	21	52	148	179	143	181	0.88
3	7	0.87	1.2e+03	0.4	0.0	21	43	176	198	174	202	0.78
4	7	0.068	97	4.0	0.0	21	45	204	228	195	232	0.88
5	7	0.00038	0.54	11.2	0.0	21	47	232	258	228	264	0.87
6	7	0.047	67	4.5	0.0	21	52	260	291	256	292	0.77
7	7	0.16	2.3e+02	2.8	0.2	21	45	288	312	284	316	0.81

Coding Sequence: ATGGATTGGGTGCTACCCCCGGAAGAAGTAAAGTTTATAGCAAACAACGATCAAGTTTGGGAAACTCCACCGAATGCAATTAGCAAGTACGAAATTAAATCGGAAGAGTTGGAAGAAGACGTAAAGTTTAACGTAGAAGATTTACATCATTCCATTGACATCAAAGAAGAAAGAAATGAGAAACCGGTAAGGAAGTCGGACAGCTCAAGTTTAATCGAGTGTACAATTTGTGGGTTTCAAGACAGACGTAAACGCACATTGAAAGTTCATCTCAGAACTCATGCGGATGAGCGAACATGTGTTTGTCAAATTTGTGGTTACAAATGTGATGCAAACACCCATTTGAAATATCATAGAGACAAGAAACCGTTTTCCTGCGAATATTGCGGTTTTAAATGTGCGTATAagcattatttaaatgaacatttaaaaacccACACGGGAGAGAAGCCGTATGtgtgtgaaatttgtaattataagtgTGCGCAAagggcaaatttaaaaatacatatgaAAATACACACTGGTGAGAAGCCCGTAGCTTGCGGCTtgtgcgattataaatgtagaGATAAATGGGTATTGAAAATGCACTCAAAAATCCATACCGGAGAGAAACCCTTTGGATGCCAGCTATGCGACTACAAATGCACGcagaaatcaaatttaactGTGCATTTGAAAACTCACACCGGGGAGAAGCCGTTTGCTTGTCATATTTGTGGCAATACATTCAGACATAAAGCCAACTTAAAAATGCACCTAAAAACTCACACCGGTGAGAAACCGTACGGTTGTGATCTTTGCGACTACAAATGTCTGCATAAATCAAATCTAAAGACCCATTTGAAAGTACACACCGGAGAAAAGCCCTTTGCTTGTaacatttgtgattataaatgcaCTCAGAAAGCTCATTTACAAATGCATTATTCGAAAACTCATGCCGGCTAG
Protein Sequence: MDWVLPPEEVKFIANNDQVWETPPNAISKYEIKSEELEEDVKFNVEDLHHSIDIKEERNEKPVRKSDSSSLIECTICGFQDRRKRTLKVHLRTHADERTCVCQICGYKCDANTHLKYHRDKKPFSCEYCGFKCAYKHYLNEHLKTHTGEKPYVCEICNYKCAQRANLKIHMKIHTGEKPVACGLCDYKCRDKWVLKMHSKIHTGEKPFGCQLCDYKCTQKSNLTVHLKTHTGEKPFACHICGNTFRHKANLKMHLKTHTGEKPYGCDLCDYKCLHKSNLKTHLKVHTGEKPFACNICDYKCTQKAHLQMHYSKTHAG

Sequence clustering based on sequence similarity using MMseqs2