Basic Information

Transcription Factor Domain

TF Family: zf-GAGA
Domain: zf-GAGA domain
PFAM: PF09237
TF Group: Zinc-Coordinating Group
Description: Members of this family bind to a 5'-GAGAG-3' DNA consensus binding site, and contain a Cys2-His2 zinc finger core as well as an N-terminal extension containing two highly basic regions. The zinc finger core binds in the DNA major groove and recognises the first three GAG bases of the consensus in a manner similar to that seen in other classical zinc finger-DNA complexes. The second basic region forms a helix that interacts in the major groove recognising the last G of the consensus, while the first basic region wraps around the DNA in the minor groove and recognises the A in the fourth position of the consensus sequence [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 8 0.12 1.7e+02 3.2 0.0 24 47 93 116 86 123 0.84

2 8 0.057 81 4.2 0.1 26 52 124 150 117 152 0.89

3 8 0.44 6.2e+02 1.4 0.2 22 44 148 170 145 174 0.85

4 8 0.012 17 6.4 0.3 21 45 175 199 170 206 0.82

5 8 0.018 25 5.8 0.0 21 48 203 230 198 235 0.81

6 8 0.14 2e+02 3.0 0.0 21 45 231 255 228 259 0.84

7 8 0.0018 2.5 9.0 0.1 21 45 259 283 255 292 0.83

8 8 0.008 11 7.0 0.1 22 48 316 342 312 344 0.90

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	8	0.12	1.7e+02	3.2	0.0	24	47	93	116	86	123	0.84
2	8	0.057	81	4.2	0.1	26	52	124	150	117	152	0.89
3	8	0.44	6.2e+02	1.4	0.2	22	44	148	170	145	174	0.85
4	8	0.012	17	6.4	0.3	21	45	175	199	170	206	0.82
5	8	0.018	25	5.8	0.0	21	48	203	230	198	235	0.81
6	8	0.14	2e+02	3.0	0.0	21	45	231	255	228	259	0.84
7	8	0.0018	2.5	9.0	0.1	21	45	259	283	255	292	0.83
8	8	0.008	11	7.0	0.1	22	48	316	342	312	344	0.90

Coding Sequence: ATGTCCGAAAAAAATGAAGTGAGTTTGTATGTTAACAGTGAACTAGATGCTGTTATTAAGGAAGAACGAGAGGAGACTTGCAGTGATGAAAATAACGAACATGTGCATGATACGTTGGAAGCTATAAAACAGAACACGATCTACATTTGCAATATCAAACAAGAAACTACCGACTACAGATCTGAAAGCTCTGACAATAACGACGAAGAAACAGAAGACTTAGGAATTCGTTCtgacgaaattaaaatatgtgaaaCTGACACACACAACGATAAAAGATTTACATGTTCGATATGTAACATGAgatttaaatggaaaaataatttgatgagtCACATGAAAGTGCACAATTCCAACAAAAGGGATTTTGTTTGCACCACATGTAATGCAAGCTTCAGGTGGAAGAATAATTTGGTAAGTCATGTAAAAATTCATACACACGAAAAGCCGTATGCGTGTGAAGTGTGCAGCAGTAAGTTCACAACTCAACGATATCTCCACAGTCACAAACAAATTCACGCCTCCGAAAAACGACACATATGCCCGATCTGTAACGCTCAATACGCCTGGAAAGTGAGCTTGGACAGGCACATTAGATCTCATACCGGCGAAAAACCtttttcttgcaaaatttGCCATATCAAATTTGCGGGTAGAAGCAATCTGCACACCCACATGACGGTTCATTCCGACGAAAAACCGTTTGCATGcaaaatttgcgattttaaattttcgcgaAAGTACAACTTAAACAGTCACATGAAGACGCACAAAAAAGAGAAACCTTATTCGTGTGAAATTTGTCAAGCCAAATTTGCGGGGAAAAGCAGCTTAAGGAGACACGAACAATCCCATTCTGGTGAAAAACCTTACGTATGTGATCAGTGTGATTCGAAATTTACTCGAAAGTACATTTTAGACAGTCACATGCTGACTCACACGCACGACAAACCTTTTGGTTGCGAGAAGTGTAATGCTAGATTTGTGTGGAAGAGAAGTTTAAGGAGGCATATTCAAACTACGCACGAAGAGAATAACTAG
Protein Sequence: MSEKNEVSLYVNSELDAVIKEEREETCSDENNEHVHDTLEAIKQNTIYICNIKQETTDYRSESSDNNDEETEDLGIRSDEIKICETDTHNDKRFTCSICNMRFKWKNNLMSHMKVHNSNKRDFVCTTCNASFRWKNNLVSHVKIHTHEKPYACEVCSSKFTTQRYLHSHKQIHASEKRHICPICNAQYAWKVSLDRHIRSHTGEKPFSCKICHIKFAGRSNLHTHMTVHSDEKPFACKICDFKFSRKYNLNSHMKTHKKEKPYSCEICQAKFAGKSSLRRHEQSHSGEKPYVCDQCDSKFTRKYILDSHMLTHTHDKPFGCEKCNARFVWKRSLRRHIQTTHEENN

Sequence clustering based on sequence similarity using MMseqs2