Basic Information

Transcription Factor Domain

TF Family: zf-GAGA
Domain: zf-GAGA domain
PFAM: PF09237
TF Group: Zinc-Coordinating Group
Description: Members of this family bind to a 5'-GAGAG-3' DNA consensus binding site, and contain a Cys2-His2 zinc finger core as well as an N-terminal extension containing two highly basic regions. The zinc finger core binds in the DNA major groove and recognises the first three GAG bases of the consensus in a manner similar to that seen in other classical zinc finger-DNA complexes. The second basic region forms a helix that interacts in the major groove recognising the last G of the consensus, while the first basic region wraps around the DNA in the minor groove and recognises the A in the fourth position of the consensus sequence [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 0.00035 0.49 11.3 0.1 17 45 72 101 66 105 0.81

2 9 0.28 4e+02 2.0 1.0 22 43 105 126 101 130 0.76

3 9 3.1e-05 0.044 14.7 0.0 20 52 131 163 123 165 0.84

4 9 0.26 3.7e+02 2.1 0.1 21 44 160 183 156 192 0.76

5 9 0.0045 6.4 7.7 0.1 25 52 192 219 187 221 0.82

6 9 2 2.9e+03 -0.7 0.0 22 48 217 243 212 247 0.77

7 9 0.066 94 4.0 0.0 21 44 244 267 240 271 0.90

8 9 0.06 85 4.2 0.2 21 46 272 297 268 305 0.88

9 9 0.72 1e+03 0.7 0.0 22 48 301 327 298 330 0.83

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	0.00035	0.49	11.3	0.1	17	45	72	101	66	105	0.81
2	9	0.28	4e+02	2.0	1.0	22	43	105	126	101	130	0.76
3	9	3.1e-05	0.044	14.7	0.0	20	52	131	163	123	165	0.84
4	9	0.26	3.7e+02	2.1	0.1	21	44	160	183	156	192	0.76
5	9	0.0045	6.4	7.7	0.1	25	52	192	219	187	221	0.82
6	9	2	2.9e+03	-0.7	0.0	22	48	217	243	212	247	0.77
7	9	0.066	94	4.0	0.0	21	44	244	267	240	271	0.90
8	9	0.06	85	4.2	0.2	21	46	272	297	268	305	0.88
9	9	0.72	1e+03	0.7	0.0	22	48	301	327	298	330	0.83

Coding Sequence: ATGGAGTTTGAAGATGTAGCAATACCATTGAATTCTGTggaaattaaagaagaaaatgtattatttgcaGAAGACCCACTAGAAGTGGAAATAGAGGATGTCAAATGTAAAGCAGAGAACCTGCAcaactttgaaattaaagaagaaagtGTGTCGATTGTGTGTGACacttgcaacaaaaaatttacacagaAGTCAAGCTTAAAAGTTCATTCCAGGATTCATACAGGCCAAAAGCCGTTTACATGTAAAATATGTTTCTCGAAATTTGTGCGAAGTGCTCAGTTGCATCagcatttaaaagttttatgcaAGAAACCGATTACGTGCAAGATTTGTGCTTCAAAATTACCCAACCGGTGTTCCTTGCAAAATCACATGAGAAGTCATACCGACGAAAAACCGTTTGCTTGTAAACTGTGTGATgcgaaatttaaacaaaacctACAGTTACAAAGACATTTGCACGTACATACCGGTGAAAAACCGTTTGTGTGTGAAATTTGCGGTTCAAAATTTAGGATGAAATcggtttttcaaaatcatatgAGGATTCATTTAGACGAAAAACGGTATATATGCAAATTTTGCGATTCGAAATTTGTTCAAAGTACACAACTTCGTCGGCACATGAGAGTTCACActggcgaaaaaccatttCTTTGCGAAACTTGCAATTGGAAATTTTCGGATAAAACATGTTGGAAACGTCATTTAAGAATACACACGGGCGAAAAACCGTTTGGGTGCAACATGTGTGACTCTAAATTTAGACTTAAAGCACATTTGCAACGTCACGTAAGAACTCATACCGGTGAAACACCTTTTGCATGCAAAATGTGTGATTCAAAGTTTAGATGTCTTTCGCACTTACAGCGACATGTAAAGGTTCATTTAGGCGAAAAATCGTATGTGtgcaatttatgtaataagACATTTTCACAAAATGTTGGCTTGAAAAGTCATTTAGCGAGAATTCATAAACCGAAAAAGTAG
Protein Sequence: MEFEDVAIPLNSVEIKEENVLFAEDPLEVEIEDVKCKAENLHNFEIKEESVSIVCDTCNKKFTQKSSLKVHSRIHTGQKPFTCKICFSKFVRSAQLHQHLKVLCKKPITCKICASKLPNRCSLQNHMRSHTDEKPFACKLCDAKFKQNLQLQRHLHVHTGEKPFVCEICGSKFRMKSVFQNHMRIHLDEKRYICKFCDSKFVQSTQLRRHMRVHTGEKPFLCETCNWKFSDKTCWKRHLRIHTGEKPFGCNMCDSKFRLKAHLQRHVRTHTGETPFACKMCDSKFRCLSHLQRHVKVHLGEKSYVCNLCNKTFSQNVGLKSHLARIHKPKK

Sequence clustering based on sequence similarity using MMseqs2