Basic Information

Gene Symbol
ZNF341
Assembly
GCA_037893425.1
Location
JBBLXU010002870.1:28833-32643[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 13 0.1 8.5 7.1 4.4 1 23 45 67 45 67 0.98
2 13 0.00012 0.01 16.3 3.0 1 23 233 255 233 255 0.99
3 13 1.8e-07 1.6e-05 25.1 0.4 1 23 261 283 261 283 0.98
4 13 0.012 0.98 10.0 1.3 1 23 308 331 308 331 0.96
5 13 0.32 27 5.5 0.4 1 23 337 361 337 361 0.95
6 13 1.2e-05 0.00098 19.5 0.9 1 23 366 388 366 388 0.98
7 13 0.0051 0.43 11.2 3.9 1 23 400 424 400 424 0.91
8 13 0.00024 0.02 15.3 2.0 1 23 426 448 426 448 0.98
9 13 6.3e-06 0.00052 20.3 0.2 1 23 454 476 454 476 0.96
10 13 1.9e-05 0.0016 18.8 0.2 1 23 482 504 482 504 0.97
11 13 0.0095 0.79 10.3 0.3 5 23 519 537 510 537 0.79
12 13 0.012 1 10.0 7.0 1 23 543 566 543 566 0.93
13 13 0.0014 0.12 12.9 2.2 2 19 569 586 568 588 0.95

Sequence Information

Coding Sequence
ATGGCCCAATCAATATTCGACGCCTTAACAGGGGTCTCGCTTGACAGTTCAACAGTGCAATCTCTGCTCGAAACTCCGACCCTTATAAGCGAAGTTGAGCAGTCagCCATAGATCAAGATGaggaagatatttttcaatgcggCAAGTGCAAAAGTCAATTTACATCTTTGCACATGTTTCTACTCCACAAGAGAGAACACCTGAAAGTACAAGAGCAAACTGTAGATCTGAGTCAGTATTTGGTCAACGAAGACACCCAAGTCGACGTCAATGCACAAGATCCGTGTCAGAATGGTATTCCTTACGATCCGCATGAAGGATTTGTTCAAAGCGATCAGCTAGCCGAATCCATCATACTCGAGGAGACCGATATGTTGTTCAGTATGGATCAAGAAGGTGCGAATTATCTGACACAAGACTCTGGTTTCGGAGTGCCTATAATCCTCAATGctgaaaatctcgaaaatgcTTTTTCCGATCCGGCTGAAAATACAGAAACGGATTCATTGATAAACGAAACTGAAGAAGTGGGTCAAACTTTGCACAGCGATCTCAATCAGAACGAGACTGTTTTTGAAGTCTCTTCGAATCATGACATGGTCCCAATGGAAAATGGATTGGAAAACGTTATTGAGAATCATGACGAACAAACGGAAGAAGAGGACAGCAACGTCGGTCAAATGCAGAATTTAAAaTACAAATGTGGCTATTGCAACAAACAGtttgccaaaaaattttattggcaaCAACACGAGCGGTCGCACACTGGTGAAAAACCTTATCAGTGCGTGGTCTGTGGCAGAGCATTTGCACAGAAATCCAACGTCAAAAAGCACATGTCCTCGCACAAAGTTTGGCCAGGAACTGCGATACACTCACTACCGCCGGAGGCACCACCGGATGGAAGTATCGATCGTACCTATCACTGTCAATTCTGCAAAGAGATTTTCGACTCGTACAAAGCCCTCAAGGGTCACTTAATCGTTTCTCATTTGACGCTAAAAGTTTACAAATGCGTTCAAAGTAGCTGCAGCATGATGTTCGCCGAACTGGACGATTTTCTCGAGCACACCAAGAGCCACAAACGTTCCGAGTACCGATGTCACGTGTGCGGTGAAATCTTCAACACACTCTCCGATCTTGGACTCCATCAGTACACCCATTCCGTCCAAAAGCAAAAAACTACGGAAAAGTATTATTGTTGCTCGGTCTGCAAATCATCTTTTTCTAATCTCGAGGCGTTGCAACATCATACAGAAACCACGACTCACGATTACGCCTGTCCTCACTGCGGCAAAAGCTTTttgatcgaaagatttttacgAAGACATCTCAAAACTCATGTATCTTCGGCTCGTTTCGCCTGCGACGATTGCGGCAAAGCTTTTAAAACCGAACAATATCTCGCCAATCACAAATTAATACACAGCGAGGAAACGCCATTCATTTGTCCACAATGTCCTGCAAGATTCAAGAGAAAAGATCGCTTAGGGCGTCACATGCTCATTCACGATTTAACGAAACGGCTCAAGTGTCCGTTTCGTGGTTACTTGGGCTGCATGAGTGAATTTTCACGCCCGGACAAACTGAAGAGACATCTTTTAACTCATAGCAACATCAAACGTTTCAGCTGTAGTCATTGTAATCGTAATTTTCATCGGGCCCAAGCTCTTAAACATCACGAACTCAACAAACACAATCTCAAGTGTGACATATGTTCACATGCATTTAAAACTAAGGATCAACTAATAACACACAATTGTGACCAAGCAATGGAGACGAAAAAACATCCGAGTTCGCAACTCCCAAAAAAAGCTTCTGGAACGTTCAAGCCACGAAAACCGACGCCAAAGAGACAAATGAAATCGGCAAGTGGCATCacggaaaaggaaaaatcaaaaactgacgaaatacaaaaaaagATCATTTTggaagatataaaaatgagcgATTACGAAGATGAAGGGTGTGATAAGAGACtggaaaattttacaataaccCGAGAGATCGGTTCAACGATGGAGTCTCTCATGAATTCGGACTCGTCGGATTCAGAGGAGGTTAAGTCGgcgataaacgttttttcgtcCGAACAAATCGACGGTGTCGcgtaa
Protein Sequence
MAQSIFDALTGVSLDSSTVQSLLETPTLISEVEQSAIDQDEEDIFQCGKCKSQFTSLHMFLLHKREHLKVQEQTVDLSQYLVNEDTQVDVNAQDPCQNGIPYDPHEGFVQSDQLAESIILEETDMLFSMDQEGANYLTQDSGFGVPIILNAENLENAFSDPAENTETDSLINETEEVGQTLHSDLNQNETVFEVSSNHDMVPMENGLENVIENHDEQTEEEDSNVGQMQNLKYKCGYCNKQFAKKFYWQQHERSHTGEKPYQCVVCGRAFAQKSNVKKHMSSHKVWPGTAIHSLPPEAPPDGSIDRTYHCQFCKEIFDSYKALKGHLIVSHLTLKVYKCVQSSCSMMFAELDDFLEHTKSHKRSEYRCHVCGEIFNTLSDLGLHQYTHSVQKQKTTEKYYCCSVCKSSFSNLEALQHHTETTTHDYACPHCGKSFLIERFLRRHLKTHVSSARFACDDCGKAFKTEQYLANHKLIHSEETPFICPQCPARFKRKDRLGRHMLIHDLTKRLKCPFRGYLGCMSEFSRPDKLKRHLLTHSNIKRFSCSHCNRNFHRAQALKHHELNKHNLKCDICSHAFKTKDQLITHNCDQAMETKKHPSSQLPKKASGTFKPRKPTPKRQMKSASGITEKEKSKTDEIQKKIILEDIKMSDYEDEGCDKRLENFTITREIGSTMESLMNSDSSDSEEVKSAINVFSSEQIDGVA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2