Basic Information

Transcription Factor Domain

TF Family: zf-GAGA
Domain: zf-GAGA domain
PFAM: PF09237
TF Group: Zinc-Coordinating Group
Description: Members of this family bind to a 5'-GAGAG-3' DNA consensus binding site, and contain a Cys2-His2 zinc finger core as well as an N-terminal extension containing two highly basic regions. The zinc finger core binds in the DNA major groove and recognises the first three GAG bases of the consensus in a manner similar to that seen in other classical zinc finger-DNA complexes. The second basic region forms a helix that interacts in the major groove recognising the last G of the consensus, while the first basic region wraps around the DNA in the minor groove and recognises the A in the fourth position of the consensus sequence [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 6 0.00022 1.7 9.2 0.3 13 43 28 58 22 68 0.89

2 6 0.00038 2.9 8.4 0.1 21 48 181 208 177 214 0.91

3 6 0.07 5.5e+02 1.2 0.1 26 46 215 235 212 238 0.89

4 6 0.0093 72 4.0 0.1 21 43 238 260 234 264 0.85

5 6 5.5e-05 0.43 11.1 0.2 21 43 294 316 289 322 0.89

6 6 0.006 46 4.6 0.1 21 48 322 349 317 353 0.86

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	6	0.00022	1.7	9.2	0.3	13	43	28	58	22	68	0.89
2	6	0.00038	2.9	8.4	0.1	21	48	181	208	177	214	0.91
3	6	0.07	5.5e+02	1.2	0.1	26	46	215	235	212	238	0.89
4	6	0.0093	72	4.0	0.1	21	43	238	260	234	264	0.85
5	6	5.5e-05	0.43	11.1	0.2	21	43	294	316	289	322	0.89
6	6	0.006	46	4.6	0.1	21	48	322	349	317	353	0.86

Coding Sequence: ATGATAACTCAATGTATTTCGCCTCATGGACGTCAACAACAAGAGCTATCGATCGTAGACAAGCGGTCCACCgatttcggagaaaaaaatgcatcaaacTCGGACAATGTTGATACACTATCGTGTGAAAAATGTGCGAGAGTATTCAAGAGAGACACTAATCTGAGGAGACATCGAATCAATTGTCGCAAGAGAAGCAAAGAAGAGGACACAGGTCGCAAGGAAAATGATGatacagaaatttttcaaccgcACATTGCGCAAACGTTGGATTCGTTACATGATTTTGAGATTTCTGATAAAAGTTCGAGCTATCGATGCGATTCCTGCGATTATACGACGGAAAAGGAGAAGATGATGAAACTTCATTTACGTCAGAATCACATTGGaggtacgaagaaaaaaaaatatggagtgGCAGTGGAAACGGTGGTTAAGGCGAGAATGGAAGCAAACGATCGTGTCTATTATCATTGCGACGAGTGTGGCAAAAATCTATCATCCCTTTATACATTCGCGGGGCATATAAGGATTCACACGGGTGAGAGACCATTCACTTGTCACTTGTGCGGCAAACAATTTCGCATTAATCAGGGCTTGGCTCGTCATTTGAAAGAGACTCAtgcgagaattaaaaaattttcttgcgACGTCTGTTCTCGAATGTTCGCGACGAAACGCAACATCGAGGATCATTTGCGTATACACACCGGCGAACGTCCCTTCGTTTGCAACATATGCGGCAAAGCTTTCAGGCAAAAAGCCTCGCTCTTCGTTCACAATCGTACTCACACCGATTCCTTTCCGTTCAAATGTAATTATTGCAATCAGGCCTTTCGTACCAGACCACCTCTTGTTTTACATCTGACCAAACACACTGGTGAAAAGCCCCATACTTGCGATATATGTAATCGTGCTTTTCGCATCAAGCACGAACTCAAACGTCATCGTCTGGTACATTCGGAAGAAAAACCTTGGCAATGTACCGACTGCGATATGGCCTTTCGACAAAAACGATATCTCGTTAATCACAGAAAATCCAACCACGAGTCCCGGAGAAACTTCAAGAATTAG
Protein Sequence: MITQCISPHGRQQQELSIVDKRSTDFGEKNASNSDNVDTLSCEKCARVFKRDTNLRRHRINCRKRSKEEDTGRKENDDTEIFQPHIAQTLDSLHDFEISDKSSSYRCDSCDYTTEKEKMMKLHLRQNHIGGTKKKKYGVAVETVVKARMEANDRVYYHCDECGKNLSSLYTFAGHIRIHTGERPFTCHLCGKQFRINQGLARHLKETHARIKKFSCDVCSRMFATKRNIEDHLRIHTGERPFVCNICGKAFRQKASLFVHNRTHTDSFPFKCNYCNQAFRTRPPLVLHLTKHTGEKPHTCDICNRAFRIKHELKRHRLVHSEEKPWQCTDCDMAFRQKRYLVNHRKSNHESRRNFKN

Sequence clustering based on sequence similarity using MMseqs2