Basic Information

Gene Symbol
-
Assembly
GCA_030586385.1
Location
JAPIVC010000295.1:2149669-2152516[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 15 3.3e-05 0.0069 18.2 5.2 2 23 371 392 370 392 0.97
2 15 8.4e-05 0.018 16.9 1.9 2 23 399 421 398 421 0.95
3 15 4e-06 0.00084 21.1 0.9 2 23 517 538 516 538 0.97
4 15 1.8e-05 0.0037 19.1 3.7 1 23 544 566 544 567 0.96
5 15 0.00011 0.022 16.6 1.2 1 23 572 594 572 594 0.97
6 15 1.1e-06 0.00024 22.8 1.4 1 23 617 639 617 639 0.98
7 15 1.3e-06 0.00027 22.6 1.2 1 23 645 667 645 667 0.97
8 15 1e-05 0.0022 19.8 2.4 1 23 673 695 673 695 0.98
9 15 0.0015 0.31 13.0 0.2 1 23 701 723 701 723 0.99
10 15 4.5e-05 0.0095 17.8 1.1 1 23 729 752 729 752 0.92
11 15 2.1e-05 0.0043 18.9 1.3 1 23 758 780 758 780 0.98
12 15 0.00045 0.094 14.6 4.7 1 23 786 808 786 808 0.98
13 15 5.8e-06 0.0012 20.6 0.4 1 23 814 837 814 837 0.97
14 15 1e-05 0.0021 19.8 0.5 1 23 843 865 843 865 0.95
15 15 9.9e-07 0.00021 23.0 4.8 1 23 871 893 871 893 0.99

Sequence Information

Coding Sequence
ATGACAAaaataagaatgaataaaGAAATGCCGTTAAGTGTAGAATGGATGCCACAAAATGCATATGTACGGAGTTCCTTGGATCAGTTGCTGCCAGGTGAACGAAATCAACGCAGTTTTGTATTTGTAAAACAGGAAACAGAATTTTTTGAAAGTGCATTAAACTCACAACATGTACAAAATACAGTCGTACACTTGCAAGTTTCCtctaaagagaaagataaggAAATCAAGCAAGAAAGTAGCCATTTGGATCCTTGTCAAACAAGCCCTTTAAATCAGTCACCTAAAAAATTGACTGAGGGTTCTGAGAGATTGTATAATAGAGGTCGCGTtgatataatagaaatgaCAGTAGAACCAACATTccactataaatattttcttgtttatgAAAATCAGCCATCCAAGTTTGTTGTACTAAGAGCTCTCTGCAACAATACAGCTGAAGAAGTTGCGAAGAATTTGTTAGATGTATTGGCAATCATAGGGGCACCACGAGTACTACAGAGTGGTAATGGACGTAAGTTTGCTGAACAAGTTGTACATGAACTGCGTTTACTATGGAATGATTCCCTCATATTGCACGGGGATGTACCTAAGTGTGAAGTTAGCTGCAGGGATTTTAAAAGCTTGCTTGAATCTTGGATGAGGAAGAATCCTACCAAGACCTGGTGTGAAGGACTGAACTTTATACAGATTCTTCACAATTCAACATACTGCAGTCAGAATGGTAAAGTTCCATGCGATGTATTATTCGGACGAGATGTacgtgaaaattttcaaaactttgGTGTAGAAAAGGATACAGAGAGTCTATGGACTGAGGAAGAATGGATTGAATATTTGTCAcatggaaaaaataaagatgtagTTACAAAAGACACACAAAGGACATCGGATAGtactaatTATTGTGAAGAAAACGATAACATACAAGATACACGCAGtcaaaaaacattttcgaAAAACGACGATGTAAATGGGTTTAGTTttgtcaatataaaaaatgaatctgTCACGAGCAATGTGCATGTAACAGATTCAAATAGAGGTAAAATTGaagcagaaaaaaatgaattaaagatcGATGACAATACACAATATCTTAAATGCAAATACTGCCAAAAGCGATACATGAAGCTGGGACATTTGAAGAATCACATGAGAACTCATAAAGCGCAACGAGTTCTCCGATGCAAGTTGTGCAATAAAACATTCAGTGTCCCAAGATTATACTCGAAGCACATGAAGCAGTCGCATGGACaagataaattgattaaagctGATGAGGAAGAGGAGGTACCAGTTAGAAGAAATACCAGAAGCAATACTGCTGACACGGTAACGACCGTATCCAATGAGGAAAGATCCGAGATTCGGACATATAACGAAATTTCTGATCCCGAGACAACGGACGAAGGTTGCGATGCATTActagatgatataaaaaattcctgTAACAAGACTGCCAAGATCTCGAGTCATACTGGTAGACGAAAGTTGTCTGCGGAGAGTCGAAGCGTGTCGAAATCGCAATCTACTTTACAGTGTACATATTGCGAGCAAAAGTTTAGCTTTCCCAGCGTATTGGAGAGGCACATGCGATCGCATACGAACGAACGACCGTATGTGTGCGATGTGTGCAACAAGAGTTTCAAGCAGCTAGGTCACCTTAGCCAGCACTCGTTAACGCATCACGACTATCGCTCGTTCCAGTGCACGGTATGCGGCGTAAAATTCGATTCGCTAGACTCGCTGAAGCAACACGCGCATTCGCATAAAGGTGACACGACAACACTAacaacgatgacgacgacatCCAAGATCCGCGACGTTTATCGTCTATTTGAATGCGACAACTGCAAAAAGGTATTTACGACGAAGAGCGTGCTGGAACgacatatatttacacacactCAGGAACGTCAATACGACTGCAAGGTGTGCGGCAAACGTTTCAAGCAGGCTGGCCACGTAAAATCGCACATGCTAGTCCATACAGGCGAGCGCCGCTTCCAGTGTACCGTGTGCTCGAAACGTTTCAGCTTATCGAACTCGTTGAAGAAGCACATGTACGTGCACAACGGTGAGAAACCATATCAATGCGACGTATGCGGTGCGCGTTTCCTGGAGAAGCGCAATCTCAACGGTCATCTGCTGACGCACACCAACGAACGTCCGTATTGCTGCAAAATCTGCGGCAAACGGTACACTTTGGCGGACACTCTGCGCCGTCACGTGAGCGCCGCGCACGAGGATGGTCGTACTTATCAGTGCGAGATCTGCGCCAAGATGTTCAAGCAGCTGGCGCATCTATCGGTGCACAAAAAGGTACACAACGATGAACGACCGTTCCAGTGTCATCTGTGTGAGAAGAATTTCAAGCACAAGAACGTGCTCAAGTCGCATCTGGCGATCCACGCGAATGTACGACCGTTTGAATGCGATGTGTGCAAGGCCACATTCGTCAGGAAGACAAATCTGCAGACGCATATCTCGTCCGCGCACATGAACGAGCGTCCGTACGCCTGCACCATTTGTGGCAAGCGCTTCAAGCAGATCAGTCATCTGAACGGTCACGTCGTTGTGCATAGCAATCTGATGCCCTACAAGTGCGACTATTGCGATCGTCGATGCAATCGATTGGACAACCTGAAAAAACACATGCGTCTTCACACAAAGAACAAGGAGTAA
Protein Sequence
MTKIRMNKEMPLSVEWMPQNAYVRSSLDQLLPGERNQRSFVFVKQETEFFESALNSQHVQNTVVHLQVSSKEKDKEIKQESSHLDPCQTSPLNQSPKKLTEGSERLYNRGRVDIIEMTVEPTFHYKYFLVYENQPSKFVVLRALCNNTAEEVAKNLLDVLAIIGAPRVLQSGNGRKFAEQVVHELRLLWNDSLILHGDVPKCEVSCRDFKSLLESWMRKNPTKTWCEGLNFIQILHNSTYCSQNGKVPCDVLFGRDVRENFQNFGVEKDTESLWTEEEWIEYLSHGKNKDVVTKDTQRTSDSTNYCEENDNIQDTRSQKTFSKNDDVNGFSFVNIKNESVTSNVHVTDSNRGKIEAEKNELKIDDNTQYLKCKYCQKRYMKLGHLKNHMRTHKAQRVLRCKLCNKTFSVPRLYSKHMKQSHGQDKLIKADEEEEVPVRRNTRSNTADTVTTVSNEERSEIRTYNEISDPETTDEGCDALLDDIKNSCNKTAKISSHTGRRKLSAESRSVSKSQSTLQCTYCEQKFSFPSVLERHMRSHTNERPYVCDVCNKSFKQLGHLSQHSLTHHDYRSFQCTVCGVKFDSLDSLKQHAHSHKGDTTTLTTMTTTSKIRDVYRLFECDNCKKVFTTKSVLERHIFTHTQERQYDCKVCGKRFKQAGHVKSHMLVHTGERRFQCTVCSKRFSLSNSLKKHMYVHNGEKPYQCDVCGARFLEKRNLNGHLLTHTNERPYCCKICGKRYTLADTLRRHVSAAHEDGRTYQCEICAKMFKQLAHLSVHKKVHNDERPFQCHLCEKNFKHKNVLKSHLAIHANVRPFECDVCKATFVRKTNLQTHISSAHMNERPYACTICGKRFKQISHLNGHVVVHSNLMPYKCDYCDRRCNRLDNLKKHMRLHTKNKE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00867616;
90% Identity
iTF_00868269;
80% Identity
-