Basic Information

Gene Symbol
-
Assembly
GCA_900659725.1
Location
CAACVG010013403.1:122507-134813[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 16 0.33 23 5.8 1.4 1 23 108 130 108 130 0.96
2 16 0.053 3.7 8.3 1.0 2 23 136 157 136 157 0.97
3 16 0.0023 0.16 12.6 7.9 1 21 163 183 163 185 0.95
4 16 1.1e-05 0.00079 19.9 2.1 1 23 191 213 191 213 0.97
5 16 0.00033 0.023 15.2 2.3 1 23 220 242 220 242 0.97
6 16 0.017 1.2 9.8 2.6 2 23 249 270 248 270 0.96
7 16 0.0048 0.34 11.6 1.2 1 23 275 298 275 298 0.97
8 16 0.00034 0.024 15.2 2.1 3 23 303 323 301 323 0.97
9 16 0.00017 0.012 16.1 0.8 2 23 330 352 329 352 0.95
10 16 2.4e-06 0.00017 22.0 1.0 2 23 360 381 360 381 0.98
11 16 6.2e-07 4.4e-05 23.8 0.5 1 23 385 407 385 407 0.97
12 16 8.7e-06 0.00061 20.2 6.0 1 23 413 435 413 435 0.98
13 16 0.075 5.3 7.8 1.0 1 19 441 459 441 461 0.94
14 16 0.00016 0.011 16.2 2.1 1 23 469 491 469 491 0.99
15 16 1.9e-05 0.0013 19.1 4.5 1 21 497 517 497 521 0.92
16 16 0.0021 0.14 12.7 0.3 1 21 529 549 529 552 0.87

Sequence Information

Coding Sequence
ATGGCACGAATTGGCAGTGAAAGCCATCAAATAAAGATAAAAGAGGAACCTCCCGATTGCCCCGAGTTTCCAGGATACATAAAACAGGAACCAGATTCAAAAAacttccaaaaaataaaaagtgaaTATCCAGATGTATATGACAACagtaaaagtataaataatatagaaaaaTTATTAACCAAAGATGAAataaaggaagaagaagaagataagtATGAATTGTCTCCCTCAGATTTGGAAAAAGAATTTGAGAAGTTCAACAAAGAGGATGAAAAGGTTAACAGTGGGAAAACTAAACTAGCTAACAATGCAACCGCTTACAAGTGTCAAATGTGCGAAGAGATATTCTTGAAATTTGCAGAATATAAGATTCATAAGAAGAATCATTACATAGAAAAGAGGAGGTGCAAAATTTGCAACGTTGTATGCCAGAGCATAGGAAAATTGGCTGACCACCTCAACAAACACCTAGGCTTAAAACCATTCAAGTGTGATGAGTGTGATAAGTCATTCATCTCAAAGCACCATGTCAAACTCCATAAAAGATGCCATAGTACAGAAAAGATTTTCAAGTGTACCAAGTGCGAGAAAGCCTTCAAAAATCGGATGTCTTTGAGAAGCCACCTTGTTAGTCACTATGAAAAAATTAAGGAATTTATTTGTAAGGTTTGCAAGAAAGAATGTGCAGACTTAGCAAGCCTCCGACATCATATGGTCTCTCATGGCAATGTGGTAGAGATAAAATGTGGCGTTTGCAACAAAAAATTCAACAACGATCGAAGTTTGGAATGCCATCTCAGTACCCACAAAGAGCTGAAGTTCCCCTGTGATTTTTGTGGAAAGATATACCAGTCAATGTATAGGATAAAGAGGCACATCAAGAGGTCTCACATTCGGAGTCACTGTGATGTGTGCAATGAGgtATTTTTTGATCGAGCTGCGTTCACGCGTCACAAAAAGACCCACGACGATTCGAAACCTACCGAATGTGAATTTTGTCAGAGAAAATTCGCCAAGGCGAAAAATTTGAGCGAGCACATCAGACTGCAACACAAAAAGGATGAGGAGGTGAGGAAATGTAACATTTGCGAAAAGGAGTTCATCAATCTGTCGCTGTTGAAAAACCACCTGAAAACGCATGACAAATGCTTCAAGTGCCCTGATTGTGACATGGTTTTCTCATCCAGGTACAATTTGGAGACCCACTCTGTCACCCACACCGGCGCCAGGAACCACAAATGCCACATCTGCCAAAAGTCGTACTCTACGAGAACCAGTCTGAAGAACCATTTGGCCACGCACAGCGACGTCCGCTCATTCCAATGTGACGTCTGCGCGAAGCTGTTCAAAACAAACAGAAGACTGTACGTCCACAAGTTCTGTCATGCGACCGAAGAGAAGTACCAGTGCGAGATATGCTTGCAGAAGTTCAAGGTGAAGCAGTACCTGAAGTACCACATGATCAAACACTCCACCGTCAAACCGTTCGAATGTAACATATGCAAAAAGCGCTTCAAGCACAAGAAGTCATTTGAAAAGCACATGACGCTGGGCAGACACAGAAAAGTGATGGATACCGAACATGACTGCGATTTCTGCGACGAAACCTTTCCCAGCAGGGAAGAACTCATCGAGCACTTTGAAGATGTGCATCACGAAGAGAATATCATCAACAATCTCGAAGATATGGAGGAGAGCGTTGCTGTTAAGATAGAAATTGAGGATGAGGAGGACGAGAGATCGTGTTGA
Protein Sequence
MARIGSESHQIKIKEEPPDCPEFPGYIKQEPDSKNFQKIKSEYPDVYDNSKSINNIEKLLTKDEIKEEEEDKYELSPSDLEKEFEKFNKEDEKVNSGKTKLANNATAYKCQMCEEIFLKFAEYKIHKKNHYIEKRRCKICNVVCQSIGKLADHLNKHLGLKPFKCDECDKSFISKHHVKLHKRCHSTEKIFKCTKCEKAFKNRMSLRSHLVSHYEKIKEFICKVCKKECADLASLRHHMVSHGNVVEIKCGVCNKKFNNDRSLECHLSTHKELKFPCDFCGKIYQSMYRIKRHIKRSHIRSHCDVCNEVFFDRAAFTRHKKTHDDSKPTECEFCQRKFAKAKNLSEHIRLQHKKDEEVRKCNICEKEFINLSLLKNHLKTHDKCFKCPDCDMVFSSRYNLETHSVTHTGARNHKCHICQKSYSTRTSLKNHLATHSDVRSFQCDVCAKLFKTNRRLYVHKFCHATEEKYQCEICLQKFKVKQYLKYHMIKHSTVKPFECNICKKRFKHKKSFEKHMTLGRHRKVMDTEHDCDFCDETFPSREELIEHFEDVHHEENIINNLEDMEESVAVKIEIEDEEDERSC

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00249151;
90% Identity
-
80% Identity
-