Basic Information

Insect: Calliphora vomitoria
Gene Symbol: ftz-f1
Assembly: GCA_942486075.2
Location: CALNXM020000286.1:114892-127536[+]

Transcription Factor Domain

TF Family: SF-like
Domain: zf-C4|SF-like
PFAM: AnimalTFDB
TF Group: Zinc-Coordinating Group
Description: The ligand binding domain of nuclear receptor steroidogenic factor 1 (SF-1): SF-1, a member of the nuclear hormone receptor superfamily, is an essential regulator of endocrine development and function and is considered a master regulator of reproduction. Most nuclear receptors function as homodimer or heterodimers, however SF-1 binds to its target genes as a monomer, recognizing the variations of the DNA sequence motif, T/CCA AGGTCA. SF-1 functions cooperatively with other transcription factors to modulate gene expression. Phospholipids have been determined as potential ligands of SF-1. Like other members of the nuclear receptor (NR) superfamily of ligand-activated transcription factors, SF-1 has a central well conserved DNA binding domain (DBD), a variable N-terminal domain, a flexible hinge and a C-terminal ligand binding domain (LBD). [1, 8, 3, 11, 6, 5, 12, 10, 9, 2, 4, 7]
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 2 6.3e-15 6.5e-11 42.5 0.6 7 79 1 73 1 103 0.67

2 2 5e-73 5.2e-69 233.8 2.0 155 408 173 419 149 421 0.91

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	2	6.3e-15	6.5e-11	42.5	0.6	7	79	1	73	1	103	0.67
2	2	5e-73	5.2e-69	233.8	2.0	155	408	173	419	149	421	0.91

Sequence Information

Coding Sequence: ATGCGCGGCGGTAGAAATAAGTTTGGACCCATGTACAAAAGAGATCGAGCGCGAAAATTGCAAGTGATGCGACAACGACAAATTGCATTGCAGGCCCTGCGAACGTCTATGGGTACGGGAGAAATGAAAGCGACACCTCTCTCGCCCGGCTACCAGCAGGCCTACACAAATATGAATATAAAACAAGAAATACAAATACCTCAGGTATCCTCTCTAACACAATCACCCGACTCATCACCCAGCCCCATAGCTATTGCCTTAGGTCAGGTTAATGCCAGCTCTGGTGTGATAGCGACACCTATGAACGGCAGTAGTGGTGCTGGTGGAGGCGGTGGCGGAGGAGGAGGCGGCGGTGGTGGTGGCAATAGTGGCAACAACAACAACAGCAGCAATACAAGTGATGGCATCAACCGCGTTGGTAGTGGCAGTGGTGGTGGCAGTGGTAATTGCCATGAAACTGGCACAGGATCCTTACAAAGTGCCAGCGATTCAAAACTGTGCTTCGACTCGGGCACACATCCTTCTAGTACCGCCGATTCCATAATAGAACCTTTAAGGGTCTCACCGATGATCAGAGAATTTGTACAGTCAATAGATGACAGGGAATGGCAAACGCAACTATTCGCGTTGCTGCAAAAACAAACGTACAATCAAGTTGAAGTGGATCTCTTTGAATTAATGTGTAAAGTTTTAGATCAAAATCTATTTTCCCAAGTTGATTGGGCCCGTAATACTGTGTTCTTTAAAGATTTGAAGGTCGACGATCAAATGAAACTTCTACAACATTCATGGTCCGATATGTTAGTATTGGATCACCTACATCAGCGCATACACAATGGCCTGCCCGACGAAACCCAACTGAATAACGGTCAAGTCTTTAATCTCCTCAGTTTAGGCCTACTGGGCGTACCACAGCTGTCCGACTATTTCAATGAGTTGCAAAATAAATTGCAGGATTTGAAATTCGATATGGGCGATTATGTGTGTATGAAATTTTTAATTTTATTAAATCCAGATGTACGAGGTATTATCAATAAGAAAACTGTATTGCAGGGTCATGAAAATGTACAAGCAGCGTTATTAGATTATACATTAACGTGTTATCCATCTGTGACGGATAAATTTAGGAGGCTGTTAAGTATACTGCCAGACATACATGCGATGGCAGCGCGTGGTGAAGAGCACTTATATTCAAAACACTGTGCCGGCAGTGCACCCACACAAACGTTACTCATGGAAATGTTGCACGCAAAACGAAAGGTGTAA
Protein Sequence: MRGGRNKFGPMYKRDRARKLQVMRQRQIALQALRTSMGTGEMKATPLSPGYQQAYTNMNIKQEIQIPQVSSLTQSPDSSPSPIAIALGQVNASSGVIATPMNGSSGAGGGGGGGGGGGGGGNSGNNNNSSNTSDGINRVGSGSGGGSGNCHETGTGSLQSASDSKLCFDSGTHPSSTADSIIEPLRVSPMIREFVQSIDDREWQTQLFALLQKQTYNQVEVDLFELMCKVLDQNLFSQVDWARNTVFFKDLKVDDQMKLLQHSWSDMLVLDHLHQRIHNGLPDETQLNNGQVFNLLSLGLLGVPQLSDYFNELQNKLQDLKFDMGDYVCMKFLILLNPDVRGIINKKTVLQGHENVQAALLDYTLTCYPSVTDKFRRLLSILPDIHAMAARGEEHLYSKHCAGSAPTQTLLMEMLHAKRKV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01357984;
90% Identity: iTF_01176970;
80% Identity: iTF_00259829;