Basic Information

Insect: Calliphora vicina
Gene Symbol: Hr39
Assembly: GCA_958450345.1
Location: OY288233.1:125381721-125389254[-]

Transcription Factor Domain

TF Family: SF-like
Domain: zf-C4|SF-like
PFAM: AnimalTFDB
TF Group: Zinc-Coordinating Group
Description: The ligand binding domain of nuclear receptor steroidogenic factor 1 (SF-1): SF-1, a member of the nuclear hormone receptor superfamily, is an essential regulator of endocrine development and function and is considered a master regulator of reproduction. Most nuclear receptors function as homodimer or heterodimers, however SF-1 binds to its target genes as a monomer, recognizing the variations of the DNA sequence motif, T/CCA AGGTCA. SF-1 functions cooperatively with other transcription factors to modulate gene expression. Phospholipids have been determined as potential ligands of SF-1. Like other members of the nuclear receptor (NR) superfamily of ligand-activated transcription factors, SF-1 has a central well conserved DNA binding domain (DBD), a variable N-terminal domain, a flexible hinge and a C-terminal ligand binding domain (LBD). [1, 8, 3, 11, 6, 5, 12, 10, 9, 2, 4, 7]
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 3 1.1 1.9e+04 -4.4 9.3 72 160 274 379 228 429 0.48

2 3 2.5e-16 4.6e-12 47.1 13.2 1 154 500 691 500 703 0.71

3 3 5.2e-79 9.2e-75 253.6 0.3 185 408 687 898 683 898 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	3	1.1	1.9e+04	-4.4	9.3	72	160	274	379	228	429	0.48
2	3	2.5e-16	4.6e-12	47.1	13.2	1	154	500	691	500	703	0.71
3	3	5.2e-79	9.2e-75	253.6	0.3	185	408	687	898	683	898	0.95

Sequence Information

Coding Sequence: atgtctaccattaaaacagaaaatataaCCGGAGGAATGGGAGGAGGAGGAGGTGCAGTGGTTACCACTTCAACAACGGGAGGCACAACATTTCAATTACCCATAAATATGAGCAATACAGCAGGTGTTGGTGGTATAACCACCACAACTTGTACAACCACCACTACCAGGAATAATGTATCCGTGACAAATATCAAATGTGAAGTGGATGATGGTGGTAATTCGTCGTCTTCAACGAATGGCAATATTGTATCGGTGGGATTTTATAATGGTTCTAGTGGTATAAGAGGGGGAAGTGTAATAACATCGGGTCATGGTATACGAATACCGGTGACCAAAGCGGAGGACTCGGACTCAGAGACGGAACTGACACATATAGAAAATTTGAAAGTTACCCGACGAGTGGCCAGTTCTTCTAGTTCCGTTCACAATCATCATAATGGACCGCGGCCCATGTCTTGGGAGGGCGAATTGTCTGAGAATGAAGATACCCGCGAAGCTGAGTTAATGGATACGGATACTACCATGAGcaatggtggtggtggtggtggcatGCAGGAACCCTCAAATGCAGTGGCTGTTATAAAAAGTGAAGCTACCACCACAACTCCCTCCTCAACGGGCATGGGAGGTCCTCTAATTAAAACGGATACCGAACAACTAATGTTAGATATACATCATGCAGCCTCTGCTGGTAATTTATATCATCCCAAACTGAAGTTGGCTCCCACACAAAGTGATCCCATCAATTTGAAATATGAACCACCGGATCATTCGGCTTTGGTGAATTCTCCTTTGATGGCCCGCCAGAAGTCTACCACAGCTTTGCCTCATTTACCTGCCAATCCCAGTCCAGATTCTGCCATACATTCCGTTTACACCCACAGCTCACCCTCCCAATCGCCCCTGACATCAAGGCATGCTCCCTATACTCCTTCGCTGTCGCGCAACAACAGTGATGCCTCTCATAGTTCTTGCTATTCTTACTCCTCGGAATTCAGTCCCACTCACTCACCCATACAGGGCAGACATCCAGCGCCTCATGGAGTGTATGGTAGTTTTAATGGAGCCACGGCCAATAGCTTACAACATTCCGCATTACTGTATAGACCCATGATGGGTTCTACGCAAACGGCTCAATCAGTTAAATTAGATAGTGGATCGAGTGAGGTGCAAAACTTATCTATGGATGCCACATCCTCCTCATCGTCCTTTAACATGACTACCGACTCCGGCTTACCAGCCTCCCCAGCAGCTGGCATTTCAAGGCAACAGCTAATCAATTCACCCTGTCCCATTTGTGGCGATAAAATATCTGGTTTTCATTATGGCATCTTTTCATGCGAGTCCTGCAAAGGTTTCTTTAAGCGTACCGTCCAAAATCGTAAGAATTATGTCTGCGTACGGGGAGGACCATGTGCGGTTAGCATTACAACGCGCAAAAAGTGCCCAGCCTGTAGATTTGATAAATGCCTGCAGAAGGGCATGAAACTGGAAGCTATACGAGAGGATCGCACACGTGGCGGCCGTTCTACTTATCAGTGCTCCTACACTTTGCCCAATTCCATAATGAGTCCTCTACTCTCGCCcgaacagcagcaacagcagaaTTCTACACAAAATCTAATGGCTggtcaacagcaacaacaacattcacAATTGCAACATCAATTGCAGCAACGTTTAAATCCTCCCCTACAATCGTCTCACCAAGCCAATGGTTACGGTAATCCAAATACAACTACCATAAAAACCGAGCAAACAGATATTTATGGCAAGAATCTGCCAGCCGCCCATTCTCCTTCAATGAATGGCTTAAATTCGTCGCGTTCACATTCTCATAACGCTAGTAATGCCTCATCATCTTCGTGCTCCTCCGCCTCCTCCAATTCGCTGCATCACAACAGTATTCCCCAacttttgcaagaaatcatGGATGTTGAACATCTCTGGCAATACACGGACGCCGAATTGGCACGACTCAATCAACCGTTGACCTCGTCGTCCAGTTCGGCATCGCTGAATTCCAATTCGACGGATTCTTCTGCAGCTGCCAATCAAATGACCAATCCACTGCTGGCCAGTGCTGGTCTTTCGTCTAGCACCAATCCGGATTTGATTGCCCATCTGTGTAAGGTGGCCGATCATCGTCTGTACAAGATCGTAAAGTGGTGTAAGAGTTTGCCGCTATTCAAGAATATATCGATTGACGATCAAATTTGCCTACTCATCAACTCATGGTGTGAACTTTTACTCTTCTCCTGTTGCTTTCGCTCCGTCGACACACCGGGAGAAATTAAAATGTCACTGGGCAAAACAATAACACTGCCACAAGCTAAACTCACTGGTTTTCAGccCTGCATTGAAAGAATGCTGAATCTGACAGATCATTTAAGACGTTTACGTGTCGATCGTTATGAATTTGTGGCTATGAAAGTCATTGTGCTGCTGCAATCAGATACTTCCGAACTACAAGAACCCGTTAAGGTCAGAGAATGTCAAGAGAAGGCTTTGCAAAGCTTACAGGCCTACACACTGGCCCACTATCCCGAAAGTCCATCTAAATTTGGTGAATTATTGCTGCGCATACCCGATCTACAGAGAACTTGTCAGTTGGGCAAAGAAATGCTGTCTATTAAATCTCGTGATGGTGGTgactttaatttattaatggAACTTTTAAGAGGAGAACATTGA
Protein Sequence: MSTIKTENITGGMGGGGGAVVTTSTTGGTTFQLPINMSNTAGVGGITTTTCTTTTTRNNVSVTNIKCEVDDGGNSSSSTNGNIVSVGFYNGSSGIRGGSVITSGHGIRIPVTKAEDSDSETELTHIENLKVTRRVASSSSSVHNHHNGPRPMSWEGELSENEDTREAELMDTDTTMSNGGGGGGMQEPSNAVAVIKSEATTTTPSSTGMGGPLIKTDTEQLMLDIHHAASAGNLYHPKLKLAPTQSDPINLKYEPPDHSALVNSPLMARQKSTTALPHLPANPSPDSAIHSVYTHSSPSQSPLTSRHAPYTPSLSRNNSDASHSSCYSYSSEFSPTHSPIQGRHPAPHGVYGSFNGATANSLQHSALLYRPMMGSTQTAQSVKLDSGSSEVQNLSMDATSSSSSFNMTTDSGLPASPAAGISRQQLINSPCPICGDKISGFHYGIFSCESCKGFFKRTVQNRKNYVCVRGGPCAVSITTRKKCPACRFDKCLQKGMKLEAIREDRTRGGRSTYQCSYTLPNSIMSPLLSPEQQQQQNSTQNLMAGQQQQQHSQLQHQLQQRLNPPLQSSHQANGYGNPNTTTIKTEQTDIYGKNLPAAHSPSMNGLNSSRSHSHNASNASSSSCSSASSNSLHHNSIPQLLQEIMDVEHLWQYTDAELARLNQPLTSSSSSASLNSNSTDSSAAANQMTNPLLASAGLSSSTNPDLIAHLCKVADHRLYKIVKWCKSLPLFKNISIDDQICLLINSWCELLLFSCCFRSVDTPGEIKMSLGKTITLPQAKLTGFQPCIERMLNLTDHLRRLRVDRYEFVAMKVIVLLQSDTSELQEPVKVRECQEKALQSLQAYTLAHYPESPSKFGELLLRIPDLQRTCQLGKEMLSIKSRDGGDFNLLMELLRGEH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01259264;
90% Identity: iTF_00045401;
80% Identity: iTF_00258954;