Basic Information

Transcription Factor Domain

TF Family: zf-GAGA
Domain: zf-GAGA domain
PFAM: PF09237
TF Group: Zinc-Coordinating Group
Description: Members of this family bind to a 5'-GAGAG-3' DNA consensus binding site, and contain a Cys2-His2 zinc finger core as well as an N-terminal extension containing two highly basic regions. The zinc finger core binds in the DNA major groove and recognises the first three GAG bases of the consensus in a manner similar to that seen in other classical zinc finger-DNA complexes. The second basic region forms a helix that interacts in the major groove recognising the last G of the consensus, while the first basic region wraps around the DNA in the minor groove and recognises the A in the fourth position of the consensus sequence [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 5 0.029 3.2e+02 2.8 0.1 21 47 82 108 66 113 0.80

2 5 2.8e-05 0.31 12.5 0.3 23 45 112 134 109 137 0.91

3 5 0.00012 1.3 10.5 0.5 20 48 137 164 133 168 0.88

4 5 0.018 2e+02 3.5 0.1 21 44 166 189 163 196 0.91

5 5 0.00026 2.9 9.3 0.0 23 46 196 219 191 224 0.90

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	5	0.029	3.2e+02	2.8	0.1	21	47	82	108	66	113	0.80
2	5	2.8e-05	0.31	12.5	0.3	23	45	112	134	109	137	0.91
3	5	0.00012	1.3	10.5	0.5	20	48	137	164	133	168	0.88
4	5	0.018	2e+02	3.5	0.1	21	44	166	189	163	196	0.91
5	5	0.00026	2.9	9.3	0.0	23	46	196	219	191	224	0.90

Coding Sequence: ATGGTCTACGATCCATGGTCTATGGTGCGTGGTGTATGGTCCACGGTTTATGGTCTTTGGTACACGGTGTCACCAAAAAGCAAAAATTTAAATTATTACGCTTCCTCAAATACTGGTTCTACCATGTCTGCTGCCGATCAATTCCAATTACAAGCAGCTCCAGTGTACAGCTGTAGGCGATGCAAAAAGACATTCTCAACAAAGCGTGAACAAAATCTACATAAACGGGAAAATCATGAACACTCACAATCCTCCTACGAGTGCAAATtgtgttcaaaatttttctgcaataaTGGAAACTTGGAGCGTCATATGAAGGTGCACAATGACATTCGTCCTTATACATGCGAAATATGTCACAAAGCATTCTCTCAGGCTGTAAATCTGCAACGTCACTACTCAGTGCATAATGGTGAGCGTCCTTATCAATGCAGTTTCTGTCAAAAGGCTTTTACGCAGCAAAGTAACATGCGTCGTCATGAGCTAACGCATACTGGTGAAAAACCATTTGGCTGTAAACGTTGTAATCGCTTCTTTTCTCAGCGCATTAATTTGAAAAAGCATATTATGGGCCATCTAAATACACGGCCATATATGTGTGGCATTTGCCAAAAATCGTTTATACAGTCAGCCAActttaaaaaacatctaaaagtGCACGTCAAGGATGGAAAATTTGTGGACGAGGCAGCGGCTTTAGCAGCTATGGCGGATATTAAACCGAACACAACAAATGAGCCTGTCGCTTTTGAGTGTGCTCTCTGCCGTTCcgtatttgataatttttcaagttttgaatcGCATGAAACTCGCTGCAATGGTATACCAAAAGATGGTGTTGTACATGTCGAGAACACTAGAAACGCTATAGGACCGATAGGTCATTATGCGCCCATACATTTTACAGTAACAAATTTAGATGGCAATGAGATAATCGTGCAAACAAGCagataa
Protein Sequence: MVYDPWSMVRGVWSTVYGLWYTVSPKSKNLNYYASSNTGSTMSAADQFQLQAAPVYSCRRCKKTFSTKREQNLHKRENHEHSQSSYECKLCSKFFCNNGNLERHMKVHNDIRPYTCEICHKAFSQAVNLQRHYSVHNGERPYQCSFCQKAFTQQSNMRRHELTHTGEKPFGCKRCNRFFSQRINLKKHIMGHLNTRPYMCGICQKSFIQSANFKKHLKVHVKDGKFVDEAAALAAMADIKPNTTNEPVAFECALCRSVFDNFSSFESHETRCNGIPKDGVVHVENTRNAIGPIGHYAPIHFTVTNLDGNEIIVQTSR

Sequence clustering based on sequence similarity using MMseqs2