Basic Information

Insect: Calliopum simillimum
Gene Symbol: Smarce1
Assembly: GCA_951812925.1
Location: OX638372.1:44056359-44058441[-]

Transcription Factor Domain

TF Family: HMG
Domain: HMG_box domain
PFAM: PF00505
TF Group: Other Alpha-Helix Group
Description: High mobility group (HMG) box domains are involved in binding DNA, and may be involved in protein-protein interactions as well. The structure of the HMG-box domain consists of three helices in an irregular array. HMG-box domains are found in one or more copies in HMG-box proteins, which form a large, diverse family involved in the regulation of DNA-dependent processes such as transcription, replication, and strand repair, all of which require the bending and unwinding of chromatin. Many of these proteins are regulators of gene expression. HMG-box proteins are found in a variety of eukaryotic organisms, and can be broadly divided into two groups, based on sequence-dependent and sequence-independent DNA recognition; the former usually contain one HMG-box motif, while the latter can contain multiple HMG-box motifs. HMG-box domains can be found in single or multiple copies in the following protein classes: HMG1 and HMG2 non-histone components of chromatin; SRY (sex determining region Y protein) involved in differential gonadogenesis; the SOX family of transcription factors [1]; sequence-specific LEF1 (lymphoid enhancer binding factor 1) and TCF-1 (T-cell factor 1) involved in regulation of organogenesis and thymocyte differentiation [2]; structure-specific recognition protein SSRP involved in transcription and replication; MTF1 mitochondrial transcription factor; nucleolar transcription factors UBF 1/2 (upstream binding factor) involved in transcription by RNA polymerase I; Abf2 yeast ARS-binding factor [3]; yeast transcription factors lxr1, Rox1, Nhp6b and Spp41; mating type proteins (MAT) involved in the sexual reproduction of fungi [4]; and the YABBY plant-specific transcription factors.
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 3 1.9e-18 3.4e-15 57.5 2.7 1 68 94 161 94 162 0.98

2 3 3.2 5.6e+03 -0.9 1.1 48 68 275 295 264 296 0.80

3 3 9.5 1.7e+04 -2.4 0.4 50 66 312 328 310 331 0.62

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	3	1.9e-18	3.4e-15	57.5	2.7	1	68	94	161	94	162	0.98
2	3	3.2	5.6e+03	-0.9	1.1	48	68	275	295	264	296	0.80
3	3	9.5	1.7e+04	-2.4	0.4	50	66	312	328	310	331	0.62

Sequence Information

Coding Sequence: ATGGCTCTGCCCAGTAGTTATAAACAAATAGCAGTTGGTGCACCTACTGGTTCAACAACGCCAGCACCCACAACCACTTCATCTAGTGGAAGTGGGGGCGGTGGCGGTAGCCGGTCGCGGTCCTCTGGATCTGGAGCGGGTGGCGATCGTAATAAGGATACTACGCCCATTTTTACTCACAGCAATTATGGTAACCCAGCTTTTACGCCACAAAAGGCTGGCAAATCTGCAAGTTCCAAGAATCAAAGTGAATCGCGTGCGCCAAAACCGCCGAAGCCGCCAGAGAAACCGGTACTGCCATACATGCGCTATTCTAAACGCATTTGGGATAGTGTCAAAGCCATGAACCCCGATTTAAAGTTGTGGGAACTTGGCAAAAAAATCGGCGCAATGTGGAAGCTGTTGAGTgagacggaaaaacaggaataCCTGGATGAGTATGAATCGGACAAATTGGAATACGAAAAAGCACTAAAGGCGTATCACAACTCTCCCGCTTATTTGACATACATGGCAGctaaaagtaaagtaaaaactgATGCAGATGTCCATGAAACACCTTCCCGCTCAGGTGGTAAAGGTCAGCAGGAACGCCGCATTGATATTCAGCCTGCAGAAGATGAAGACGATCAAGATGAGGGCTACTCCTTTAAGCACATAGCATATGCTCGTTATTTGCGCAATCATCGACTGatcaatgaaattttctctGATGCTGTGGTACCTGATGTTCGCTCCGTCGTGACCACACAACGCATGCAAGTATTAAAGCGTCAAGTCAGCTCGTTGACTATGCATCAGACTAAATTAGAGGCGGAATTGCAGCAGATGGAAGAAAAATTTGAGGCCAAAAAACAGCGCATGATGGAGTCTAGCGAAGCGTTTCAGGAGGAATTGAAGCGGCACTGCAAACCTGCTGTAGATGACGATACTTTCcaaaaaatggtacaaaaaaTGTACGAGGAAATGCGACGCGACCGCCAGCGCATGGAAACGGATCCAGCGGCAGCAGCGCATGCAGCTGTTAATCGTGCAGAAGACAAAGGATTTCCTGGAGGTTCGCACCCTATAAATGCGCCCAGTGATAGCAGTGCACAGTCAGCTGttgCTAAGAAAGAAGTAGCATCTTCACCTCCGGTAAAGCCAATTCTTGAAGCATCAAGCAAAACTGATCCTGAACCTATGGATATAGAACCAACAGCAAAGCCATCTGTTCCGTTGCCACCAAAATCCGAGACGCGTCCTGCGGAACCAATTCATGTGCAAAAACCACAAACTTCTGTTGACAACAAAGAGATACCCAAACCTCCAAATGTTGCTGTTAAATCAACTCATACATCGAATGCAGTCCCACCACCAACAACACCACCATCTGCAACACCGGAACAACCTACGTTTTCTGCACCGACAGCAACGGCAAATAACATGCCACCCACTCAACCACCAGCAGCTTCGCAACAGCAGCCACCACCACcgccgcaacaacaacaaattccaTCATCTATGCCAATGCATCCACATGGACATCCACCATCAGCCCCGCACCCACATTTACCCCCACATTTGCCACCTCATCAGCCCATGCCACCACACTCTGGATATGGCAGTTATGGCGCACCTTCTGGCCCGACGCGTTCTCCATACTATCAACCTCAATACGGTGCACATCCTTCGCAACCTTACGGTCAATACGCTCCTTACTCACACTATCAGCAACCTTATGGTCCGCCTCCTGGTCCTCACTATATGAGCCCGCGTCCACCGCCACAACATAACGGTTCACCGGTGCACTACCCGGATCATAATGTTCCCGTAGGACAGCCGCAACAAGGACCACCTGGGCACATGCCACCCCATGATGTATATGGGCAACCACATAATGTTGTACCACCACAACAGCAACCAGTTCCAGCAGCAGCTCCTCCACCAGGTGGGGCTGGTGCTCCTCCAGCGAATGGACCTCCACTAGGTGGTGGTGGTAGCGTAGATGTCGCTGCAAAAAATGATTCCGATAAGGAGAGCGATTAA
Protein Sequence: MALPSSYKQIAVGAPTGSTTPAPTTTSSSGSGGGGGSRSRSSGSGAGGDRNKDTTPIFTHSNYGNPAFTPQKAGKSASSKNQSESRAPKPPKPPEKPVLPYMRYSKRIWDSVKAMNPDLKLWELGKKIGAMWKLLSETEKQEYLDEYESDKLEYEKALKAYHNSPAYLTYMAAKSKVKTDADVHETPSRSGGKGQQERRIDIQPAEDEDDQDEGYSFKHIAYARYLRNHRLINEIFSDAVVPDVRSVVTTQRMQVLKRQVSSLTMHQTKLEAELQQMEEKFEAKKQRMMESSEAFQEELKRHCKPAVDDDTFQKMVQKMYEEMRRDRQRMETDPAAAAHAAVNRAEDKGFPGGSHPINAPSDSSAQSAVAKKEVASSPPVKPILEASSKTDPEPMDIEPTAKPSVPLPPKSETRPAEPIHVQKPQTSVDNKEIPKPPNVAVKSTHTSNAVPPPTTPPSATPEQPTFSAPTATANNMPPTQPPAASQQQPPPPPQQQQIPSSMPMHPHGHPPSAPHPHLPPHLPPHQPMPPHSGYGSYGAPSGPTRSPYYQPQYGAHPSQPYGQYAPYSHYQQPYGPPPGPHYMSPRPPPQHNGSPVHYPDHNVPVGQPQQGPPGHMPPHDVYGQPHNVVPPQQQPVPAAAPPPGGAGAPPANGPPLGGGGSVDVAAKNDSDKESD

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00972175; iTF_01486160;
90% Identity: -
80% Identity: -