Basic Information

Insect: Calephelis nemesis
Gene Symbol: ZEB2
Assembly: GCA_002245505.1
Location: NJDD01001617.1:147817-163589[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 13 5.8 4.8e+02 2.1 0.3 2 23 6 27 5 27 0.94

2 13 0.0031 0.26 12.4 0.8 1 23 982 1005 982 1005 0.93

3 13 6.2e-05 0.0052 17.8 1.8 2 23 1107 1128 1106 1128 0.97

4 13 0.00014 0.012 16.7 2.8 1 23 1134 1156 1134 1156 0.98

5 13 0.0075 0.63 11.2 2.5 2 23 1163 1184 1162 1185 0.95

6 13 0.27 23 6.3 1.6 5 23 1198 1216 1196 1216 0.97

7 13 0.007 0.59 11.3 1.3 3 23 1223 1244 1222 1244 0.97

8 13 0.0056 0.47 11.6 0.2 2 23 1261 1281 1260 1281 0.96

9 13 0.00042 0.035 15.2 1.4 1 20 1287 1306 1287 1309 0.91

10 13 0.0058 0.49 11.6 1.3 1 23 1317 1339 1317 1339 0.98

11 13 0.0053 0.45 11.7 7.2 1 23 1345 1367 1345 1367 0.98

12 13 7.8e-06 0.00065 20.6 1.5 1 23 1373 1397 1373 1397 0.98

13 13 0.00065 0.055 14.6 4.9 1 23 1403 1425 1403 1426 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	13	5.8	4.8e+02	2.1	0.3	2	23	6	27	5	27	0.94
2	13	0.0031	0.26	12.4	0.8	1	23	982	1005	982	1005	0.93
3	13	6.2e-05	0.0052	17.8	1.8	2	23	1107	1128	1106	1128	0.97
4	13	0.00014	0.012	16.7	2.8	1	23	1134	1156	1134	1156	0.98
5	13	0.0075	0.63	11.2	2.5	2	23	1163	1184	1162	1185	0.95
6	13	0.27	23	6.3	1.6	5	23	1198	1216	1196	1216	0.97
7	13	0.007	0.59	11.3	1.3	3	23	1223	1244	1222	1244	0.97
8	13	0.0056	0.47	11.6	0.2	2	23	1261	1281	1260	1281	0.96
9	13	0.00042	0.035	15.2	1.4	1	20	1287	1306	1287	1309	0.91
10	13	0.0058	0.49	11.6	1.3	1	23	1317	1339	1317	1339	0.98
11	13	0.0053	0.45	11.7	7.2	1	23	1345	1367	1345	1367	0.98
12	13	7.8e-06	0.00065	20.6	1.5	1	23	1373	1397	1373	1397	0.98
13	13	0.00065	0.055	14.6	4.9	1	23	1403	1425	1403	1426	0.96

Sequence Information

Coding Sequence: atggATCAAAGGGTTCAGTGCCCTGTTTGTACTCTGTATCTCCACAGTGGGATGACATTGGAGTCCCATTTGGATACACATCCAAAGGATCAAGTCATAAAGGCTTTGTGCAATCTATCAGCAAAAGGTACTAGTTATGGGAGTAGGACTTCGACTCCGACACACTCAGAACGCTCATACAGGAGTCGGTCAAGAACGCCAGCTACAGAGGACAGTTTAAGATGGACAAATTCACATAGAACTACTGACAGTGAGAAATATTGGAGGAGAACACCAAGTAGGAACAAATCCACATCATTGGCTAGTTCAAGGAATGGGACTCCAGATATAAGAATGAGTAACATATCATTTGAGAATAACTTGATAAACTCTTCTGACACATATGCAGTACGATTAGATAAACCTCACCAAACATTTGGAAATGGAGATTCACCCTCCATAGCCCACTTTGATCAACAATATCCTTATTACAATGCACAACAAGAGGATCCAGAAATCAAGTTTTCCCGTAGCTCTGAGTATACTGGAATGGAAagtacaaacaatatttttgcatATAATATGCCAACTGTATCCCCTAGCATCAAGTTACAGACAACAGTTGTTCCTTCGCTCTCTAAAAGAGCTAATGATGTTGTGAAAATAGTGCCTAAACAAGGAAATGTCCTTTTAAAAACCAATGTAGGTGGTGTACAATATATAACACCTGGAGTGAAACCTTTACATGTTGTAATGCCATCTCCATCATTTGTTCAGAAAAACATACATAGCAATATGATTATGACCGGTAACTTACCAAATGCTCAGATTTTAGATCCAAAAACTGTAGCATCCCCCTTAAACAGTCAATTTAACCAAATATCAACAGGTTCTATAACTCCCGGGACAACAGTTGTTACCCAAAACTCACAGATTATTTATAGAGAGATGGTACATAATATTGATGGAAAACCATTCATTTCTAGTATGCCAACTGTACTTGGTGGACATGATACCATCTCAAATGTTGCTCAAAGTAGTTCTATGTATCAAAATGTCATGGTTGTAGACCAGTTTGGTAATACTTCATGTATGTATACTACACCACAACAATTGTTAACTAAACCATGTGAGACACCAATATTTAATGAAAGTATTCCACATATGGGAATTGATAAACCTGTGCCTAATATAGTTACGGATCCTAATAAAACACTTGTCATTGAAGTAAATCCAAtagtacctataacatctacctCTGTAAGTGAGCCTGGTACAAGCAATTTACCTACACAGACCACTACGACTGTTAGACTAGAAAAAGTTGCAGCTGAAAAAGTTAGTGTTGAAAAATCTGATCCTAAAAATGATGTTTCTGTGTCCAATAAgggtttaaaaattttaagcaatATTAAAGTAGAAGTCCCAGTCCAACATCACAAGAATATGTTAAATACTATTATGGATTTGACTGGTCCAAATGATACTGAATATACTCAGAGACCATTAAGTCCAGATAAGATTTTACCAGATTTAGATGACAATACTACAAATGTTAATGAAAATTCTTTGCAACCTGCGGCAAATAGTGATTTAGTTCCTCATACTTTCTCTGTAATAAAGAATGTTGGGAATCCACCGTCTTATAAAGAGGCTTCCAAAGCAAGTACTAGTAGTAAATTAGATGTGGAATTTTCTGATAGCTGTCCCGTACCTGATCTTATTTGTAATGAAAAGGCATCAATCTCTCCTTGTAGTGAACTGTCAGAACATGGAGATAATTCAGTCGATCACCCTCCTCTTTCTCCTAAgactgaaaatgaaaatgaaaacattaCAAACATAGTTGTAGAAACTGAAAAGAAATCACCACAGAAACCTGTTAGAAGTGTCCCACTTCGacttaataacatttatgtgaagaagaacaaaaaaatcttacaaataaaaaatgctaaatcTTTTAGCACTACTACTAATACTGAAATTGTTCCATTGCCATCATCTTCAAAAGTACCTGAAACATATACAATGAACAAGAAACATGAAGATGTTGATGATAAAACTCCCATGTTAACCACTATATCAATTGAAAAGGAAAGTAATGATCATAATTTTGATGCTGACACTGAAGAGCAGTCAATGGACATAGAACCAGAGGCTTCATCTGCTTTAAATGGTGATCAATATACATCACACTCTGATTTAGTACCAATAAAAGAAGAGATAAACCTTAGTAATGAATTTAGTAATGAGTCCTCTGGTCAACATATGGCACCAATGGAAAGTCTTCGACCAATTAATGTAATTACATATGGTAATATGGCAGTTGATGactttgatgatgatgattcaaATCACAGGGAACTATTAGAACTTGAAGCTGCTTCTAAAAGTAAACAGTTTGTTACCATGATGAATGAAAACTATTTTGGTGATAATATTTATGCTGATTATTTTACACCTGACCGTGTAGAGACTTTTGATACTGAAAAAGATACTACTTTTGTGAAAGATGGACCAAAAGATCCAATGTACATTTGGGGTGAGCCATCTCAGAAGGAATCCGAATTTGTACTTCCAAACTTTATTCACGAGAGTTATAAAATAGCTGAGAGTGGTGTTGATTACTCAGACATGGGAACAGTGGAAGTGCAAATAGAGGGAGAAGGCGACAAGTGTGAAAGAATTACAAAAGCCGAGTTGTTATGTGAAAGCAGAAGTGAAGGAGAGccaatgttaaatatttgtactgATGAGAGAATGCCACCTAGAGGAGAGTTGAGTGGACAAGAGAGCAACGGAGATTTAGAGTCACCATGGAGTGGGATTTATTCAGAAGTCCCGCCGGCCGAGACTTATGATCTAATTGCACGTGAAAGTTGGATTTCCGATGGATCAGAAGTTGATGCAAGTGAAAAGAACGATACTTTggatGAAGAACTTCACTTCCCCAAAAGATTGTACACATGTGCACATTGCAGTATCAAATTTCCGAGTTTAAAAGAGTTACGAGCCCACAAATCTTTGGCGCATGCTTTACCAACATGCTCTACTACTAAGACCACGTACAGTCGGATGGTGACATCAAGAATAATAAAGAAAGAGGAAAAGCCAGATACCAGCGTACTTGCAGGAAGTATTCTCCAAATTGACTCTAAAGAGACTATTTCATCGACAATTCTCCAAGTTTACGACGTGAAGTCGGAGTCCAAACCTTTAGCTGGGCTCATCAAACAAGAACCTAAGAGACGGAGGAAGGACTATGTCTGTCCAACGTGCAAGGAAGATCAGCTGACTGACACACAGTTCCATGAACACCTCAAGATCCATCCTCTGGAGTGTCTCACGTGTGGGAAGTGTTTCTTCAAACGTGCTAATTTGGCCTTGCACATCAAAACCCATTTGGGGATAAAGAATTATAAATGTGATGTATGTGAGAAGCGTTTCATCACCCGTCAGAAGCTGAACGATCATCACAACATCCACACAGGGCGGACCCCCGTTAAGTGTACCGTCTGCGATGACACCTTCCGGCGATATTCCAACATGGTGCAGCATAGGGATCGTCACCATTTCAAGAAGAAAGTGAAAGTGCGCGACTTCGTGTGCCACTGCGGCGCGGTGTTCCACTCGAAGGCCAAGCTGGTGTGGCACAAGGAGACGCACGAGGAGAAGCCCAAGGCGTGCCAGTACTGCAGCGACAAGTTCGTGCACGCCGCCTCCCTCACGCGGCACGTGCGCCGCTCACATAACGAGTACTACCTGTCCGAGCGGCGGGCCGGCAAGGTGGAGAACGTGCCTTGTCAGATTTGTAAACAGGTGTACCTCAGATCGAATCTGCGCGCCCATTTACTGACGCACACCGGGAAACGTCCTTACAACTGCGTCATATGCAATAAGTACTTCACCACAAAGTGGAACCTGAAGCTCCACCGCTGGACCCACATGAGCCGCTCGGCCAAGCCGTACAAGTGCAACCTGTGCAAGGGCGCCTTCATCCGGCACACCGAGTACGTGTCCCACATGAACGCGCACAAGTCCGTGCGGCCCTACACCTGCAACTACTGCGGCTGCCAGTTCATCCGCAAGTACAACTGCCAGCGCCACGTCAGGGAGCACGAAATGGCCAAGAAGTATGTCTGCAAAGTGGCCGAGTGCGGGAAAACCTTCCACCGTAGTTACTATCTGTCGGAACATATGAAAGTACATAGTGGCGTTAGACCGTATTCGTGTAATATATGCGGGAAGACCTCGAGTAACAAGTCCAACCATAATAAACACGTGAAGATACACCATGCCAGGGAGCCGGTTGCGGCTGAAGCGTAA
Protein Sequence: MDQRVQCPVCTLYLHSGMTLESHLDTHPKDQVIKALCNLSAKGTSYGSRTSTPTHSERSYRSRSRTPATEDSLRWTNSHRTTDSEKYWRRTPSRNKSTSLASSRNGTPDIRMSNISFENNLINSSDTYAVRLDKPHQTFGNGDSPSIAHFDQQYPYYNAQQEDPEIKFSRSSEYTGMESTNNIFAYNMPTVSPSIKLQTTVVPSLSKRANDVVKIVPKQGNVLLKTNVGGVQYITPGVKPLHVVMPSPSFVQKNIHSNMIMTGNLPNAQILDPKTVASPLNSQFNQISTGSITPGTTVVTQNSQIIYREMVHNIDGKPFISSMPTVLGGHDTISNVAQSSSMYQNVMVVDQFGNTSCMYTTPQQLLTKPCETPIFNESIPHMGIDKPVPNIVTDPNKTLVIEVNPIVPITSTSVSEPGTSNLPTQTTTTVRLEKVAAEKVSVEKSDPKNDVSVSNKGLKILSNIKVEVPVQHHKNMLNTIMDLTGPNDTEYTQRPLSPDKILPDLDDNTTNVNENSLQPAANSDLVPHTFSVIKNVGNPPSYKEASKASTSSKLDVEFSDSCPVPDLICNEKASISPCSELSEHGDNSVDHPPLSPKTENENENITNIVVETEKKSPQKPVRSVPLRLNNIYVKKNKKILQIKNAKSFSTTTNTEIVPLPSSSKVPETYTMNKKHEDVDDKTPMLTTISIEKESNDHNFDADTEEQSMDIEPEASSALNGDQYTSHSDLVPIKEEINLSNEFSNESSGQHMAPMESLRPINVITYGNMAVDDFDDDDSNHRELLELEAASKSKQFVTMMNENYFGDNIYADYFTPDRVETFDTEKDTTFVKDGPKDPMYIWGEPSQKESEFVLPNFIHESYKIAESGVDYSDMGTVEVQIEGEGDKCERITKAELLCESRSEGEPMLNICTDERMPPRGELSGQESNGDLESPWSGIYSEVPPAETYDLIARESWISDGSEVDASEKNDTLDEELHFPKRLYTCAHCSIKFPSLKELRAHKSLAHALPTCSTTKTTYSRMVTSRIIKKEEKPDTSVLAGSILQIDSKETISSTILQVYDVKSESKPLAGLIKQEPKRRRKDYVCPTCKEDQLTDTQFHEHLKIHPLECLTCGKCFFKRANLALHIKTHLGIKNYKCDVCEKRFITRQKLNDHHNIHTGRTPVKCTVCDDTFRRYSNMVQHRDRHHFKKKVKVRDFVCHCGAVFHSKAKLVWHKETHEEKPKACQYCSDKFVHAASLTRHVRRSHNEYYLSERRAGKVENVPCQICKQVYLRSNLRAHLLTHTGKRPYNCVICNKYFTTKWNLKLHRWTHMSRSAKPYKCNLCKGAFIRHTEYVSHMNAHKSVRPYTCNYCGCQFIRKYNCQRHVREHEMAKKYVCKVAECGKTFHRSYYLSEHMKVHSGVRPYSCNICGKTSSNKSNHNKHVKIHHAREPVAAEA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00257253;
90% Identity: iTF_00257253;
80% Identity: -