Cnem016505.1
Basic Information
- Insect
- Calephelis nemesis
- Gene Symbol
- -
- Assembly
- GCA_002245505.1
- Location
- NJDD01002004.1:495184-497018[-]
Transcription Factor Domain
- TF Family
- HMGA
- Domain
- HMGA domain
- PFAM
- AnimalTFDB
- TF Group
- Unclassified Structure
- Description
- This entry represents the HMGA family, whose members contain DNA-binding domains, also known as AT hooks due to their ability to interact with the narrow minor groove of AT-rich DNA sequences. They play an important role in chromatin organisation [1]. The high mobility group (HMG) proteins are the most abundant and ubiquitous nonhistone chromosomal proteins. They bind to DNA and to nucleosomes and are involved in the regulation of DNA-dependent processes such as transcription, replication, recombination, and DNA repair. They can be grouped into three families: HMGB (HMG 1/2), HMGN (HMG 14/17) and HMGA (HMG I/Y). The characteristic domains are: AT-hook for the HMGA family, the HMG Box for the HMGB family, and the nucleosome-binding domain (NBD) for the members of the HMGN family [2].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 4 0.0069 1.9e+02 2.4 3.2 11 16 13 18 11 19 0.82 2 4 0.14 4e+03 -1.8 3.5 12 15 33 36 32 50 0.69 3 4 2.7e-10 7.7e-06 26.1 3.7 4 22 54 72 52 72 0.90 4 4 0.69 1.9e+04 -4.0 6.9 10 15 87 92 87 93 0.81
Sequence Information
- Coding Sequence
- ATGTCTGACGATGGATCAACGGTCGTAGAGAAAAAAGGACGCGGTAGGCCTAAATCTAATGGAACCCAAGCGGAAGCTAAAGGTGACGCCAAGAAAAGAGGTCGCCCTGCCGCGCCAGCAGCGAAAGCTAAAGAATCAAAAAATTCTTCAGATGACGAGCAAGCGCCAGCAGTCAAAAGAGGTAGAGGTAGACCAAAGGGATCTAAGAAAAAGTCTGCTGCCAGAGGAAAGgcTGCTGCTGGTGGTGGTGGTGAAGGAAGAGGACGTGGAAGGCCACGTAAAGAAGCTCCACCTAAAAAAGATGCCGGTTCATCTGAAGAGGAACAAGACGAAGATGAGGATGAAGAAGGGTCTGACCAGTGA
- Protein Sequence
- MSDDGSTVVEKKGRGRPKSNGTQAEAKGDAKKRGRPAAPAAKAKESKNSSDDEQAPAVKRGRGRPKGSKKKSAARGKAAAGGGGEGRGRGRPRKEAPPKKDAGSSEEEQDEDEDEEGSDQ
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_01115716;
- 90% Identity
- iTF_00256930;
- 80% Identity
- iTF_00256930;