Basic Information

Insect: Bradysia coprophila
Gene Symbol: -
Assembly: GCA_014529535.1
Location: NW:3683000-3688459[+]

Transcription Factor Domain

TF Family: BTB
Domain: zf-C2H2|ZBTB
PFAM: PF00651
TF Group: Zinc-Coordinating Group
Description: The BTB (for BR-C, ttk and bab) [6] or POZ (for Pox virus and Zinc finger) [1] domain is present near the N-terminus of a fraction of zinc finger (Pfam:PF00096) proteins and in proteins that contain the Pfam:PF01344 motif such as Kelch and a family of pox virus proteins. The BTB/POZ domain mediates homomeric dimerisation and in some instances heteromeric dimerisation [1]. The structure of the dimerised PLZF BTB/POZ domain has been solved and consists of a tightly intertwined homodimer. The central scaffolding of the protein is made up of a cluster of alpha-helices flanked by short beta-sheets at both the top and bottom of the molecule [2]. POZ domains from several zinc finger proteins have been shown to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes including N-CoR and SMRT [5, 3, 4]. The POZ or BTB domain is also known as BR-C/Ttk or ZiN.
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 5 7.7e-17 1.1e-14 54.3 0.1 11 108 28 123 22 125 0.89

2 5 3 4.4e+02 0.9 0.0 77 105 124 152 122 156 0.86

3 5 6.6 9.6e+02 -0.2 0.0 53 87 222 253 210 259 0.79

4 5 1.3e-16 1.8e-14 53.7 0.0 11 108 391 486 385 488 0.89

5 5 3 4.4e+02 0.9 0.0 77 105 487 515 485 519 0.86

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	5	7.7e-17	1.1e-14	54.3	0.1	11	108	28	123	22	125	0.89
2	5	3	4.4e+02	0.9	0.0	77	105	124	152	122	156	0.86
3	5	6.6	9.6e+02	-0.2	0.0	53	87	222	253	210	259	0.79
4	5	1.3e-16	1.8e-14	53.7	0.0	11	108	391	486	385	488	0.89
5	5	3	4.4e+02	0.9	0.0	77	105	487	515	485	519	0.86

Sequence Information

Coding Sequence: ATGTCAATCAACCAGCACCACGCCGATGAAACTGAAGTTCTATCAGAAGATGCCAGAAATATCTGTTTGAACGCCGAGAAGGCCgatgttcatttcattttcaaatccGGGGACGAGCATGTTCCAGCCCATAAAAGCCTATTGTCCCGCGGTAGTAATGTTTTCCAAGCGATGTTTGATGGTCCGTTGAAGGAAGAAGGTGACATCGAAATCGTCGACGCAACAGCTGAAGCGTTCAAAGAATTTCTGCGCTTCTTCTACTTCAACAAGGTCGATGTGAGCATGGAACATGTGTCGAGCGTCATGTGTCTCGGCAGAAAGTACAATGTAGCAGACTGCCAGCGGTTGTGCGTAAATTCATTGGAAGCTAGCATCACAGAACTAACTGCTACTGTCGTTCTTGGTTTGGCCATCATTTATGACGAGAAGCAGCTGCAGAAATCGTGTGAATTGATCATTGCATCCCGAACGGATGACGTTTTTAAATCCGAGAATTTTCTCGTTTGTGATCGTCGAGTGTTGGAGCACATCCTCAAAATGGATCGTCTTGCGTGTACTGAAGCGGAACTGTTTGAAGCATGTATGTCATGGGTCCGAGCGACCAGTAATGAAGATCATCTGACTAGAGATATTGTCCAAACGCACTTGGGACGGTTATtctatgaaattcgattcaaagCCATGAATTTAGAGGAATTTAGCAAACTCTTGCGTGTGTATGGCGAGCTGTTCTCTGTAAATGAATACAGCGAAATTCTTCGAGTGGCTTTCGGACAGGAAAAGAAtccaaaaatattccaaatggAACAACGTTCATACGATTGGAAACACGCAAAACTAATTGTGTGTAATCGAGAAATATTGTCTAATTCAGTGTATATTTATCAAACAGTATCAGTGACACAGTTTTCATCCAATACGCGACTGTTGTTAAGATATTTTGTTGTAGACTCAATTTTCAACAACAGTGATGATCCTGTTCAAACGATTAATAATGTGGAAGCTTCTGTCATCGCCGATTCGAAAGACTTAACTCGATTCACTTGCACATTAAAATACGCAAATGAGGGATACAAGAAAGCAAAGACAATGTCAATCAACCAGCACCACGCCGATGAAACTGAAGTTCTATCAGAAGATGCCAGAAATATCTGTTTGAACGCCGAGAAGGCCgatgttcatttcattttcaaatccGGGGACGAGCGTGTTCCAGCCCATAAAAGCCTATTGTCCCGCGGTAGTGATGTTTTCCAAACGATGTTTGATGGTCCGTTGAAGGAAGAAGGTGACATCGAAATCGTCGACGCAACAGCTGAAGCGTTCAAAGAATTTCTGCGCTTCTTCTACTTCAACAAGGTCGATGTGAGCATGGAACATGTGTCGAGCGTCATGTGTCTCGGCAGAAAGTACAATGTAGCAGACTGCCAGCGGTTGTGCGTAAATTCATTGGAAGCTAGCATCACAGAACTAACTGCTACTGTCGTTCTTGGTTTGGCCATCATTTATGACGAGAAGCAGCTGCAGAAATCGTGTGAATTGATCATTGCATCCCGAACGGATGACGTTTTTAAATCCGAGAATTTTCTCGTTTGTGATCGTCGAGTGTTGGAGCACATCCTCAAAATGGATCGTCTTGCGTGTACTGAAGCGGAACTGTTTGAAGCATGTATGTCATGGGTCCGAGCGACCAGTAATGAAGATCATCTGACTAGAGATATTGTCCAAACGCACTTGGGACGGTTATTCTATGAAATTCGTTTCGGAGCCATGAACTTAGAGGAATTTAGCAAACTCTTGCGTGTGTATGGCGAGCTGTTCTCTGTAAATGAATACAGCGAAATTATTCGAGTGGCTCTCGGACAGGAAAAGAAtccaaaaatattccaaatggAACAACGTTCATACGATTGGAAACACGCAAAACTAATTGTGTGTAATCGAGAAATATTGTCTAATTCAgtgtttttttatcaaacagTATCAGTGACACAGTTTTCATCCAATACGCGACTGTTGTTAAGATATTTTGTTGTAGACTCAATTTTCAAGCACAGTGTTGATCCTGTTCAAACGATTGAGTATGTGGAAGCTTCTGTCATCGCCGATTCGAAAGACTTAACTCGATTCACTTGCACATTAAAATACTCAAATGAGGGATACATTGTACATTTTCCATATCCAATATCCATCaggtccaaaaaattttatgaaattcggatAAAGTTTCCAACTGGTGAATTCCGAAagtcgaacttttttttgagcTCAACGGTAGAGATGGAAAATAATGTCGTTGTCGTTTTCCGAGTTGACAAAGTAATGcatgacaacaaaaaatcaatcatAAAATCACTTGGatttaatttgttgaattaa
Protein Sequence: MSINQHHADETEVLSEDARNICLNAEKADVHFIFKSGDEHVPAHKSLLSRGSNVFQAMFDGPLKEEGDIEIVDATAEAFKEFLRFFYFNKVDVSMEHVSSVMCLGRKYNVADCQRLCVNSLEASITELTATVVLGLAIIYDEKQLQKSCELIIASRTDDVFKSENFLVCDRRVLEHILKMDRLACTEAELFEACMSWVRATSNEDHLTRDIVQTHLGRLFYEIRFKAMNLEEFSKLLRVYGELFSVNEYSEILRVAFGQEKNPKIFQMEQRSYDWKHAKLIVCNREILSNSVYIYQTVSVTQFSSNTRLLLRYFVVDSIFNNSDDPVQTINNVEASVIADSKDLTRFTCTLKYANEGYKKAKTMSINQHHADETEVLSEDARNICLNAEKADVHFIFKSGDERVPAHKSLLSRGSDVFQTMFDGPLKEEGDIEIVDATAEAFKEFLRFFYFNKVDVSMEHVSSVMCLGRKYNVADCQRLCVNSLEASITELTATVVLGLAIIYDEKQLQKSCELIIASRTDDVFKSENFLVCDRRVLEHILKMDRLACTEAELFEACMSWVRATSNEDHLTRDIVQTHLGRLFYEIRFGAMNLEEFSKLLRVYGELFSVNEYSEIIRVALGQEKNPKIFQMEQRSYDWKHAKLIVCNREILSNSVFFYQTVSVTQFSSNTRLLLRYFVVDSIFKHSVDPVQTIEYVEASVIADSKDLTRFTCTLKYSNEGYIVHFPYPISIRSKKFYEIRIKFPTGEFRKSNFFLSSTVEMENNVVVVFRVDKVMHDNKKSIIKSLGFNLLN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -