Basic Information

Insect: Brachyptera risi
Gene Symbol: tmem223
Assembly: GCA_964007535.1
Location: OZ023333.1:38609782-38617602[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 18 0.0043 0.38 12.4 1.5 1 23 136 158 136 158 0.98

2 18 0.00063 0.056 15.0 0.2 1 23 165 188 165 188 0.95

3 18 0.0043 0.38 12.4 0.1 1 23 211 233 211 233 0.96

4 18 0.0049 0.44 12.2 0.3 1 23 392 414 392 414 0.98

5 18 2.3e-05 0.002 19.5 4.7 1 23 422 444 422 444 0.96

6 18 0.022 2 10.1 0.8 3 23 451 472 449 472 0.95

7 18 0.11 9.9 7.9 1.2 1 23 476 498 476 498 0.93

8 18 2.5e-05 0.0022 19.4 5.0 1 23 542 564 542 564 0.99

9 18 0.0069 0.61 11.7 0.3 2 23 572 594 571 594 0.93

10 18 1.7 1.5e+02 4.2 5.5 1 23 598 620 598 620 0.98

11 18 0.0033 0.3 12.7 0.6 1 23 626 649 626 649 0.94

12 18 2.2 2e+02 3.8 4.3 3 23 654 674 653 674 0.97

13 18 6.8e-05 0.006 18.0 0.1 1 23 681 703 681 703 0.96

14 18 0.0062 0.55 11.9 0.4 2 23 710 731 709 731 0.97

15 18 0.00015 0.013 17.0 1.9 1 23 737 759 737 759 0.97

16 18 0.00089 0.078 14.5 3.2 1 23 765 788 765 788 0.98

17 18 6.2e-06 0.00055 21.3 0.1 1 23 794 816 794 816 0.97

18 18 0.00041 0.036 15.6 0.9 1 23 822 845 822 845 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	18	0.0043	0.38	12.4	1.5	1	23	136	158	136	158	0.98
2	18	0.00063	0.056	15.0	0.2	1	23	165	188	165	188	0.95
3	18	0.0043	0.38	12.4	0.1	1	23	211	233	211	233	0.96
4	18	0.0049	0.44	12.2	0.3	1	23	392	414	392	414	0.98
5	18	2.3e-05	0.002	19.5	4.7	1	23	422	444	422	444	0.96
6	18	0.022	2	10.1	0.8	3	23	451	472	449	472	0.95
7	18	0.11	9.9	7.9	1.2	1	23	476	498	476	498	0.93
8	18	2.5e-05	0.0022	19.4	5.0	1	23	542	564	542	564	0.99
9	18	0.0069	0.61	11.7	0.3	2	23	572	594	571	594	0.93
10	18	1.7	1.5e+02	4.2	5.5	1	23	598	620	598	620	0.98
11	18	0.0033	0.3	12.7	0.6	1	23	626	649	626	649	0.94
12	18	2.2	2e+02	3.8	4.3	3	23	654	674	653	674	0.97
13	18	6.8e-05	0.006	18.0	0.1	1	23	681	703	681	703	0.96
14	18	0.0062	0.55	11.9	0.4	2	23	710	731	709	731	0.97
15	18	0.00015	0.013	17.0	1.9	1	23	737	759	737	759	0.97
16	18	0.00089	0.078	14.5	3.2	1	23	765	788	765	788	0.98
17	18	6.2e-06	0.00055	21.3	0.1	1	23	794	816	794	816	0.97
18	18	0.00041	0.036	15.6	0.9	1	23	822	845	822	845	0.95

Sequence Information

Coding Sequence: ATGGAACAAGAAGACGAAAGCCTGGATTCAGATTCGCCAACCAACTGTTTCATCTGCGACGATCGTATTGTTGGCGCCGGTTTGTCCCTCCTGACTCCATATTCGAGAACAGATCTGCGTGTGAAGATCGAGCAGTTGCTGGGAGACGAAGTCATGATCATTGTCGGCCAGGAAGACCAGCTGTGTGCTCGCTGCGTTGCGTTGCTCAACCACTTCGATCAGCTCGAGGCCGACTTGGATTCCGTCAGGAGCTCTCTCAAAGGGTATCTGAATGTCAAGTACAACCTAGAAGAGGGTGACGGAGTGAACGAAGCGAGTGAAGACACGAGTCCTGTATGCGTCAAGGCAGAGAACCTGACTTACGACAGTGATGCGCTCGAAGCCCGTCAGCCCCACGTCGCTGTGTTCAAGTGCAAGTATTGTGGCTACGAGAACCGCGACCGAGAGACCCTGATGAACCACGTCAAGTCACACACAAGACGAAGAGTCATCTACAAGTGTTCTATGTGCGACAAGAAGTTTGCCAGCCGCATAGGAATCGAGAATCACATACTTTACGTGCATCGTTCTTTGTGTACCTTGCCTACGGGTAGAGCCGAGGTCAGTCCGACGACGCCACTGTACAGGACTTTCCGGTGCGGCATTTGTTCGGCAACGTACCCGACCAAAGAGGAACTGATCGAGCATTTTGAGGTTCACAGAGACGACGCACTCGTTAATGCAGTGGAAGAACAAACCGACGCGAACGCGGGAAACAATTCCAACGACGCCACGTACATCCTCGACGTGGCGCAAAACTCTCACGAGGAATACGACGCCGTACAGTTGATGCTGAAGAAGTTGCACGGCGAAGAAATTTCCGACCAACATCCGGCGGAAAGTGTTTACGATAAAAGTGACGAGACGATACACATTCAGATAACAGGCAACGAACTTTCTAGTAGCGCTTTATTGGAACATTTGAAAGTGGAATCACAATTCGATAATGACGGTGTCGAACTCGAAAAAGTCAACGAGGTGGATACTTACGACGACATGACCGACAACATGACCACACCCGACGACATGACTACACCCGACGACATGACGACACCCTACGACATCGAAGCCGACGGAAACTTTCAAAAGATCTATCCGAAACCGACCGATGAACCGCTCTCCAACGGAAAGATATACGTTTGTTCCAAGTGTGGCCTGCGAACAACGATGGTAGCGCAAATGAAGCGTCACATCAAAGGACACATAGCATTGAAAAAGAAATTACACTCTTGCCACGTGTGCAACAAGGTGTTGACAACGCGTAGCAACCTGAAGAGGCACATCAGCAACCACGACTCTGAGCCGGTGAACTGCGGCCAGTGCGAGGAGCGGCTGACGGACCGGCTGCACCTGAAGCAGCACATGGAGCGAGTCCATCCGCAAGTGTATGCCTGCTCCGTCTGCAGCCACACCTTCCCCACGCAGCAGCTGCGCAAGACCCACGAGCTGGGCCACCAAGACGTCACTCACTTCCGTTGCCCCGACGACGCGTGCCGGGCAATATTCCTCACGGAGATCCAGCTGAAGAACCACCAGTCGGCCCAGCACGGGCTGGACCCCCTAGCCGGGTCCGCGGGCAACATGTACAAGTGCAACGTCTGCCACAAGATCCTCACCACGCTGCACAACCTGCGCAGACACATGCTCAGCCACGACCGCTGCTCGGGAGCCGTCCAGTGCAACATCTGCGGGGCCGAGCTGACGGACAAGCTGCACCTGAGGCAGCACCTTGAGGAGACCCACCCCGAGACGTACAAGTGCGGCTTCTGCACGCGGCTGTTCAACAGCAAGAAGAACTGCAAGCTGCACGAGCTGACGCACCCCGAGCGGCTGTTCCACAAGTGCCCCGCGTGCGAGAAGGAGTTCCCCACGCTGAACCGCCTGAAGAAGCACCAGGCGCTGGCGCACCGCGAGCCTCACTGTCGCCACTGCGGCAAGGAGGTGCAGAACATGCGCAAGCTGATCGAGCACGAGAAGCGCCACGAGAAGTACAAGGACAAGTTCTCGTGCGTCGTGTGCGGGAAGACGTTCGGCACGCCGTCGGGTCTCAAGTACCACGCGTCGGTGCACAGCGGCCAGTACCCCGTGCGATGCGACGTCTGCGACAAGGGCTTCCACTCGAACACGGTCCTGGCGGAGCACCGCGCGACTCACACCAAGGAGATCCGCTTCACGTGCGAGCGGTGCGGCCGCAACTTCACCTCCAGCAGCACGTATCGGCTGCACCGGCTGTGGCACGACAACCCCTTCCCGTACACGTGCAACATGTGCCAGCGCAAGTTCAAGCACACCTCCGTGCTGGCGGTGCACAAGCGGCGGGCGCACACCGGGGCTCGCCCGTACAAGTGCCCGTACTGCCCCCTGGCGTTCAGCGTCAGCTCGTCGCTCAACAAGCACGTCATCCTCCACACGCGCCAGTTCCCGCACAAGTGTGCGGCTTGCGACAAGGGCTTCACGACCCGCACCAAGCTGGCACGCCACTTGGCGCGAGCTCACGACGACCGGGCCATGCTGGACGAGAAGCCCAAGCCGTGCGAGTACAAGATGGTGCTGCGGCCCGAGGAGatggagggaggggaggggggggaggaggaggtgGTCCAGCAGGACGATGAAAACACGCTGCATGATCCACACATTATTAACTTTGTTACGCTTGAAACCGTGACGATGCCCGATCACGCTATTTATGCTATCTTTGAACCAGAAACTAGCCATGTTAAGCAGTTTACTGATTCGCAAGTGCTACAAAACAAATCACCTTTCAATGTCAACACAAACGTTGTTAAAGATGTTATATTGTTCCGCTACGAAAATGGCTCGTTCTACCGTATACTGAATATCTTTGCTGTATGTCAGTTTTTGTTTTGGATGTACTTATCACATTTTTCATACACGTCATTGAAAGATACTCCAGTCGATCGTGAAAACCAAGAAGATTTGCCTTGGTGGCGAAAATTCAATCTTGGTGACAATAAATACAGAAATGGACTTACAGTTATCTGCTTCATCATTGGTTATGGTATCCTCACCGCAGCATGGGCCTTCACTCTCAAATCCGTGCGGTTCCTTATTTTACGTAAAGGTGGCGAGAGTGTTACATTCGTCACTTACGGACCCTACGGGAAGAACCGAATGATCACAGTACCAATGAATAAGGTCAGCTGTCAGGAGGGAAGGTCGGGCGCCAGAGTACAGCTGCCAGTCAAGGTTAAGGGCACGTACCTCTACTACATGCTAGACATGCGGGGAGAGTTCACCAACCCGCACCTGTTCGACTCGACCGTAGGGCTCAAGAGACCGTGGTAA
Protein Sequence: MEQEDESLDSDSPTNCFICDDRIVGAGLSLLTPYSRTDLRVKIEQLLGDEVMIIVGQEDQLCARCVALLNHFDQLEADLDSVRSSLKGYLNVKYNLEEGDGVNEASEDTSPVCVKAENLTYDSDALEARQPHVAVFKCKYCGYENRDRETLMNHVKSHTRRRVIYKCSMCDKKFASRIGIENHILYVHRSLCTLPTGRAEVSPTTPLYRTFRCGICSATYPTKEELIEHFEVHRDDALVNAVEEQTDANAGNNSNDATYILDVAQNSHEEYDAVQLMLKKLHGEEISDQHPAESVYDKSDETIHIQITGNELSSSALLEHLKVESQFDNDGVELEKVNEVDTYDDMTDNMTTPDDMTTPDDMTTPYDIEADGNFQKIYPKPTDEPLSNGKIYVCSKCGLRTTMVAQMKRHIKGHIALKKKLHSCHVCNKVLTTRSNLKRHISNHDSEPVNCGQCEERLTDRLHLKQHMERVHPQVYACSVCSHTFPTQQLRKTHELGHQDVTHFRCPDDACRAIFLTEIQLKNHQSAQHGLDPLAGSAGNMYKCNVCHKILTTLHNLRRHMLSHDRCSGAVQCNICGAELTDKLHLRQHLEETHPETYKCGFCTRLFNSKKNCKLHELTHPERLFHKCPACEKEFPTLNRLKKHQALAHREPHCRHCGKEVQNMRKLIEHEKRHEKYKDKFSCVVCGKTFGTPSGLKYHASVHSGQYPVRCDVCDKGFHSNTVLAEHRATHTKEIRFTCERCGRNFTSSSTYRLHRLWHDNPFPYTCNMCQRKFKHTSVLAVHKRRAHTGARPYKCPYCPLAFSVSSSLNKHVILHTRQFPHKCAACDKGFTTRTKLARHLARAHDDRAMLDEKPKPCEYKMVLRPEEMEGGEGGEEEVVQQDDENTLHDPHIINFVTLETVTMPDHAIYAIFEPETSHVKQFTDSQVLQNKSPFNVNTNVVKDVILFRYENGSFYRILNIFAVCQFLFWMYLSHFSYTSLKDTPVDRENQEDLPWWRKFNLGDNKYRNGLTVICFIIGYGILTAAWAFTLKSVRFLILRKGGESVTFVTYGPYGKNRMITVPMNKVSCQEGRSGARVQLPVKVKGTYLYYMLDMRGEFTNPHLFDSTVGLKRPW

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00242459;
90% Identity: iTF_00242459;
80% Identity: -