Basic Information

Insect: Brachyptera putata
Gene Symbol: tmem223
Assembly: GCA_907164805.1
Location: OU015470.1:21554351-21562111[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 18 0.0027 0.24 12.9 1.8 1 23 159 181 159 181 0.98

2 18 0.00057 0.051 15.0 0.2 1 23 188 211 188 211 0.95

3 18 0.0039 0.35 12.4 0.1 1 23 234 256 234 256 0.96

4 18 0.0044 0.39 12.2 0.3 1 23 400 422 400 422 0.98

5 18 6.2e-06 0.00055 21.2 3.8 1 23 430 452 430 452 0.97

6 18 0.02 1.8 10.1 0.8 3 23 459 480 457 480 0.95

7 18 5.2 4.6e+02 2.5 0.2 1 23 484 506 484 506 0.90

8 18 2.2e-05 0.002 19.4 5.0 1 23 548 570 548 570 0.99

9 18 0.016 1.4 10.4 0.2 3 23 579 600 577 600 0.93

10 18 1.6 1.4e+02 4.2 5.5 1 23 604 626 604 626 0.98

11 18 0.003 0.27 12.7 0.6 1 23 632 655 632 655 0.94

12 18 0.35 31 6.2 2.7 2 23 659 680 659 680 0.97

13 18 3.3e-05 0.0029 18.9 0.1 1 23 687 709 687 709 0.96

14 18 0.027 2.4 9.7 0.5 2 23 716 737 715 737 0.96

15 18 0.00013 0.012 17.0 1.9 1 23 743 765 743 765 0.97

16 18 0.00054 0.048 15.1 2.7 1 23 771 794 771 794 0.98

17 18 5.6e-06 0.0005 21.3 0.1 1 23 800 822 800 822 0.97

18 18 0.00037 0.032 15.6 0.9 1 23 828 851 828 851 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	18	0.0027	0.24	12.9	1.8	1	23	159	181	159	181	0.98
2	18	0.00057	0.051	15.0	0.2	1	23	188	211	188	211	0.95
3	18	0.0039	0.35	12.4	0.1	1	23	234	256	234	256	0.96
4	18	0.0044	0.39	12.2	0.3	1	23	400	422	400	422	0.98
5	18	6.2e-06	0.00055	21.2	3.8	1	23	430	452	430	452	0.97
6	18	0.02	1.8	10.1	0.8	3	23	459	480	457	480	0.95
7	18	5.2	4.6e+02	2.5	0.2	1	23	484	506	484	506	0.90
8	18	2.2e-05	0.002	19.4	5.0	1	23	548	570	548	570	0.99
9	18	0.016	1.4	10.4	0.2	3	23	579	600	577	600	0.93
10	18	1.6	1.4e+02	4.2	5.5	1	23	604	626	604	626	0.98
11	18	0.003	0.27	12.7	0.6	1	23	632	655	632	655	0.94
12	18	0.35	31	6.2	2.7	2	23	659	680	659	680	0.97
13	18	3.3e-05	0.0029	18.9	0.1	1	23	687	709	687	709	0.96
14	18	0.027	2.4	9.7	0.5	2	23	716	737	715	737	0.96
15	18	0.00013	0.012	17.0	1.9	1	23	743	765	743	765	0.97
16	18	0.00054	0.048	15.1	2.7	1	23	771	794	771	794	0.98
17	18	5.6e-06	0.0005	21.3	0.1	1	23	800	822	800	822	0.97
18	18	0.00037	0.032	15.6	0.9	1	23	828	851	828	851	0.95

Sequence Information

Coding Sequence: ATGGTAGTGACACTGAACTATCTGCAGAAAGATGTGCACAACATCTCACAGTTTTATTACCAAGACAAGGAGATGGAACAAGAAGACGAAGGCCTGGATTCAGGTTCGCCAACCAACTGCTTCATTTGCGACGAGCCTATTGTTGGCGCCGGAGAGTCTCTCCTGATGCCGTATTCGAGAACAGACCTGCGAGTGAAGATCGAACAGTTGCTGGGAGACGACGTTATGATCATCGTCGGCCAGGAAGACCAGCTGTGTGCTCGCTGCGTCGCTTTGCTCAATCACTTTGATCAGCTGGAGGCCGACTTGGATTCCGTCAGGAGCTCTCTGAAAGGATACTTGAACGTGAAGTACAACCTGGAAGAGGGCGACGGAGCGAATGATGCGTGTGAAGCAACGAGTGCTGTGCGCGTCAAGGCTGAGCAGTCGACTTACGACAGTGACGTGTTTGAACGACAGCCACATGTCGCTGTGTTCAAGTGCAAGTATTGCGGCTACGAGAACCGCGACCGAGAAACCCTGACGAACCACGTAAAGTCGCATACGAGACGAAGAGTCATCTACAAGTGTTCTATGTGCGACAAGAAGTTTGCTAGCCGCATAGGAATCGAGAATCACATACTTTACGTGCACCGTTCGTTGTGTACCTTGCCGACAGGTGGGGCCGAGGTCAGCCCGATGGCGCCGCTGTACAGGACTTTCAGGTGCGGCATTTGTTCGGCAACGTACCCGACCAAAGAGGAGTTGATCGAGCACTTTGAAGTTCACAGAGACGACGCAGTTGTTAATGCCGCCGCGGAAGAGCAACCCGAAGTGGACGTGGGAAACAATTCCAACGACGCCACATACATCCTAGATGTGGCGCAGAACTCTCACGAGGAATACGACGCCGTACAACTGATGCTGAAGAAGTTGCATGGCGAAGACATTTCCGACCAACATCCGACCGAAAGTGTTTACGAGAAAAGTGACGAGACGATACACATCCAGATAACGGGCAACGAACTTTCCAGTAGCGCTTTATTGGAACATTTGAAAGTGGAATCACAATTCGATAACGACGATGTCGAACTCGAAAAAGTCAACGATGTGGGTGCTTACGATGCCTTGGCGACATCTGACGACATCGAACCCGACGATAACTTTCGGAAGATTTATCCGAAACCAACCGACGGACCGGTCTCCAACGGAAAGATCTACGTTTGCTCGAAGTGCGGGCTACGAACGACGATGGTGGCGCAGATGAAACGTCACATCAAGGGACACATAGCGTTGAAGAAGAAACTACACACTTGCCCCGTGTGCCACAAAGTGTTGACAACGCGCAGCAACCTGAAGCGGCACATCAGCAACCACGACTCCGAGCCGGTGAACTGCGGCCAGTGCGAGGAGCGGCTGACAGATCGGCTCCACCTGAAGCAGCACATGGAGCGAGTCCACCCGCAGGTATACGCCTGCTCCGTCTGCAGCGACACCTTCCCCACGCAGCTGCTGCGCAAGACCCACGAGCTGGGCCACCGAGACGTGACGCACTTCCGCTGTCCCGACGACACGTGTCGGGCCATATTCCTCACCGACATCCAGCTGAGGAACCACCAGTCGGCCCAGCACGGGCTGGACACGCCCCCCGCGGGCAACATGTACAAGTGCAACGTCTGCCACAAGATACTCACCACGCTGCACAACCTGCGCAGGCACATGCTCAGCCACGACCGATGCTCGGGAGCCGTCGCGTGCAACATCTGCGGGGCCGAGCTGACGGACAAGCTCCACCTGCGCCAGCACCTGGAGGAAACCCACCCTGAGACGTACAAGTGCGGTTTCTGCACGCGGCTGTTCAACAGCAAGAAGAACTGCAAGCTGCACGAGCTGACGCACCCCGAGCGGCTGTTCCACAAGTGCCCCGCCTGCGAGAAGGAGTTCCCGACGCTGAACCGCCTGAAGAAGCACCAGGCGCTAGCGCACCGCGACCCCCGCTGCCGACACTGCGGCAAGGAGGTGCAGAACATGAGGAAGCTGATCGAGCACGAGAAGCGACACGAGAAGTACAAGGACAAGTTCTCGTGTGGCGTGTGCGGTAAGACGTTCGGCACGCCGTCGGGGCTCAAGTACCACGCGTCCGTGCACAGCGGGCAGTATCCCGTGCGTTGCGACGTGTGCGACAAAGGCTTCCACTCCAACACGGTGCTCGGGGAACACCGCGCCACGCATACCAAGGAGATCCGCTTCACGTGCGAGCGCTGCGGACGCAACTTCACCTCGAGCAGTACGTACCGGCTGCACAGGCTGTGGCACGACAACCCGTTCCCCTACACGTGCAACGTGTGCCAGCGCAAGTTCAAGCACACGTCGGTACTGGCCGTGCACAAGCGGCGGGCGCACACCGGGGCTCGCCCGTACAAGTGCCCGTACTGCCCGCTGGCCTTCAGCGTCAGTTCCTCGCTCAACAAGCACGTCATCCTGCACACCCGGCAGTTCCCACACAAGTGTGCGGCGTGCGACAAGGGCTTCACAACGCGCACCAAGCTGGCGCGACACCTGGCTCGGGCGCACGACGACCGCACCATGCTCGACGAGAAGCCCAAGCCATGCGAGTACAAGATGGTGCTGCGGCCCGAGGAGATGGAGGGGGAGGGGGAGGGGGAGGTGGAGGAGGTGGTCCGGCAGGAGGATGAGAACACGCTGCATGATCCGCACATTATTAACTTTGTTACGCTGGAAACCGTGACAATGCCCGATCATGCTATTTATGCTATCTTTGAACCCGAAACTAGCCATGTGAAACAATTGACAGATTCGCAAGTGCTCCAAAACAAATCCCCTTTCAACGTAAACACAAACGTTGTTAAAGATGTTATATTGTTCCGCTACGAAAATGGCTCATTCTACCGCATACTGAATATCTTTGCTGTGTGTCAGTTTTTGTTTTGGATGTACTTATCACATTTTTCATACACATCATTGAAAGATACCCCAGTAGATCGCGAAAACCAAGACGAATTGCCTTGGTGGCGAAAATTTAATCTTGGTGACAATAAATACAGAAATGGATTAACGGTTATCTGCTTCATCATTGGGTATGGTATCCTCACCGCAGCATGGGCCTTCACTCTCAAGTCTGTACGGTTCCTTATTTTACGTAAAGGTGGCGAGAGTGTTACATTTGTCACTTATGGGCCTTACGGGAAGAACCGAATGATCACAGTACCAATTAATAAGGTCAGCTGTCAGGAGGGAAGGTCGGGCGCCAGAGTGCAGCTGCCAGTCAAGGTCAAGGACACGTACCTCTACTACATGCTTGACATGCGAGGGGAGTTCACCAACCCCCACCTGTTCGACTCGACCGTGGGGCTCAAGAGATCGTGGTAA
Protein Sequence: MVVTLNYLQKDVHNISQFYYQDKEMEQEDEGLDSGSPTNCFICDEPIVGAGESLLMPYSRTDLRVKIEQLLGDDVMIIVGQEDQLCARCVALLNHFDQLEADLDSVRSSLKGYLNVKYNLEEGDGANDACEATSAVRVKAEQSTYDSDVFERQPHVAVFKCKYCGYENRDRETLTNHVKSHTRRRVIYKCSMCDKKFASRIGIENHILYVHRSLCTLPTGGAEVSPMAPLYRTFRCGICSATYPTKEELIEHFEVHRDDAVVNAAAEEQPEVDVGNNSNDATYILDVAQNSHEEYDAVQLMLKKLHGEDISDQHPTESVYEKSDETIHIQITGNELSSSALLEHLKVESQFDNDDVELEKVNDVGAYDALATSDDIEPDDNFRKIYPKPTDGPVSNGKIYVCSKCGLRTTMVAQMKRHIKGHIALKKKLHTCPVCHKVLTTRSNLKRHISNHDSEPVNCGQCEERLTDRLHLKQHMERVHPQVYACSVCSDTFPTQLLRKTHELGHRDVTHFRCPDDTCRAIFLTDIQLRNHQSAQHGLDTPPAGNMYKCNVCHKILTTLHNLRRHMLSHDRCSGAVACNICGAELTDKLHLRQHLEETHPETYKCGFCTRLFNSKKNCKLHELTHPERLFHKCPACEKEFPTLNRLKKHQALAHRDPRCRHCGKEVQNMRKLIEHEKRHEKYKDKFSCGVCGKTFGTPSGLKYHASVHSGQYPVRCDVCDKGFHSNTVLGEHRATHTKEIRFTCERCGRNFTSSSTYRLHRLWHDNPFPYTCNVCQRKFKHTSVLAVHKRRAHTGARPYKCPYCPLAFSVSSSLNKHVILHTRQFPHKCAACDKGFTTRTKLARHLARAHDDRTMLDEKPKPCEYKMVLRPEEMEGEGEGEVEEVVRQEDENTLHDPHIINFVTLETVTMPDHAIYAIFEPETSHVKQLTDSQVLQNKSPFNVNTNVVKDVILFRYENGSFYRILNIFAVCQFLFWMYLSHFSYTSLKDTPVDRENQDELPWWRKFNLGDNKYRNGLTVICFIIGYGILTAAWAFTLKSVRFLILRKGGESVTFVTYGPYGKNRMITVPINKVSCQEGRSGARVQLPVKVKDTYLYYMLDMRGEFTNPHLFDSTVGLKRSW

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00243496;
90% Identity: iTF_00243496;
80% Identity: -