Basic Information

Gene Symbol
-
Assembly
GCA_964007535.1
Location
OZ023326.1:9934382-9943493[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 15 0.00093 0.083 14.5 0.8 2 23 294 316 293 316 0.97
2 15 0.052 4.6 9.0 0.5 1 23 320 342 320 342 0.86
3 15 0.00018 0.016 16.7 1.3 1 23 364 386 364 387 0.93
4 15 0.0043 0.38 12.4 2.0 1 23 393 415 393 415 0.98
5 15 4.6e-06 0.00041 21.7 3.3 1 23 421 443 421 443 0.96
6 15 2.8e-05 0.0025 19.2 2.2 2 23 453 474 452 474 0.97
7 15 0.0018 0.16 13.5 2.8 1 23 480 502 480 502 0.96
8 15 1.3e-06 0.00012 23.4 1.5 1 23 508 530 508 530 0.99
9 15 0.0022 0.19 13.3 0.3 1 23 536 558 536 558 0.98
10 15 0.00011 0.0096 17.4 0.6 1 23 581 603 581 603 0.99
11 15 6.4e-06 0.00056 21.3 0.6 1 23 609 632 609 632 0.97
12 15 0.0035 0.31 12.7 2.1 1 23 666 688 666 688 0.98
13 15 6e-05 0.0053 18.2 3.5 1 23 694 716 694 716 0.98
14 15 4.9e-06 0.00044 21.6 1.2 1 23 722 744 722 744 0.98
15 15 4.9e-05 0.0044 18.5 0.6 1 23 750 772 750 772 0.97

Sequence Information

Coding Sequence
ATGTTTCAGGAAACTGATTGTGCTATGGCTACCGAGACGGACGGTTCTCTGGAAATAGCTGAAGATGATTCGATGGATCCATCGTATACACTCTCAATGGATCCAGCCAGTCTGGGACTCGTCATGGAAGAAGTGCACGCCGGTACAGAGATCCCATGGGAAGAAGAGATCGGGATAATAACCGACGAGGCGATCTGTATCGAGAATATTTTCTGTCGAGTCTGTGCCGAACAGGCGGCCGAGTTGATACCAGTATTTGAAGAGCAAGGAATGGAGCTTAGTCTTGCTGATAAGATACGATGGCATCTACCTATCACGATCTCTGAAGACGATAAACTACCCGTGAAACTCTGTCCTGCGTGCAtcactcgtctcaactcgtgtCACGACCTTGCCAACTTGTGCCTTGAGTCGGAGGCGAAGCTGGAAAGACTATTCAATATAGACGATGCAACCGAGTTTAACGAGTCAGCTAACGAGCAGAAGGTCACGAATTCCAAGAGCCCCTCGGATCATCTAATAGATGGAATGAAACAATTCAGAAAGGAGAGAATGGCagacaataaatacaataatctATCTTCTGGTGACAATTCCAATGAAGACTTTGAGACCGTGTACCTTGAAGATGCGATTGATGACGACTTGAAAGGTCAGGTTCTGGATGTCATTATTGAACCCGTCGGGATGGAATCGCTACCTGCCGGGCAGTGGAAAACGGCTAATTTGCGTGTAAAGATGCCAAAAGATTTCGCCGATTGTGACACTACCTTAAAATCGCAGATAGTCGGAGCGATCCAAGACATAATGATTGAAGAAGATCAGTCGGCAAAAACAAAAAAGAACTCGTCGATCACCAGAGGCAACAATAAAGAATGGAAATGTGACATTTGTTCTCACGTTGCGCCGCGAAAGTCGTCGCTTCTAGTCCACCAAAGACGGACGCACGCCAAATCTTTCGCTTGCTCGTACTGTTACAAAACGTTTTCCAACGGCGTCGCCAGGAGGCAACACGAGGTCGTCCACAGACCGGAAACGATAGTCGATGATGACGAAAACTCGAGACAAAACGACAACGCCGTCCCTTCTTTTGTCTGCGAGATTTGCGAGGTGTCGTTCAAGAGAAAAAAGCAGCTCGCCAATCACAACCTGGAACATCACACCGACGTGAAACAGTTCAAATGTAGTAAATGCGACAAGCAGTACGGATCTCTCACCAGCCTGGACATACATCACGCGACGCACCTGTCGGAAACCGCCTACCTATGCGACTTGTGCGGAAAGAGTTTCAAACACGTCAGCAATTTGCGCAGTCACAAACGTTCGCATCTGGGCGACGAGAAAAAGAACACCCAAGTTTGTAGCGTATGTTCGAAGGGTTTTCGATCCCGGTTTCACTTGAAAGAGCATATGAATGTGCATCAAAATAGAACGCCTTACTCGTGTGATATATGTTCCAAGAAATTCCATAAAAAGATACAGCTCCGCCAACACGGTTCCGTGCACCTCGGCCTGCAACCGTACAAGTGCAACATCTGCGGTATCCGTTTCAATCGTCGCGGCAACATGACGCAGCACCTGAAGCGCCACGAGCGCCAGCTGAAGTACACGTGCAAAGTGTGTTCGGCCGGGTTCGATCGCCTGGGCACGCTGCTGCAGCATCGCAAGGCGCACACCAAGGACGAGCTGGACGATGCCATCTACCGGCAGGTGGCGGCCGACGATTCCGTCCAGGAGGCGTACAAGTGCGAGATATGCAACAAGCTGCTCGCCAAGAAGGAGACGCTCATGCTGCACATGAGGTCGCACTCGGGCGAGAAGTTGTTTGCGTGCGAGGTTTGTGGCAAGAAGCTCTCCAATAAGGGTTCGTTGACATACCACATGCGTTCGTATCATACTGGAGAGCGTCCATACTCGTGTCAGTATTGCACGGACGCGTTCCTGACACGCGAGGCGTGTTCGGTCCACGAACGGATCCACACAGGCGAACGTCCCTACTTCTGCACGGTCTGCAAGATGGGCTTCCGTTGTTCAAGCAACCTGGCTCAACACGTGCGCGTTCATACCAACGTCCGGAACCACCAGTGCGAGCACTGCGAGAAGTCGTTCCTGCGCAAGGGGGCGCTGACCGTTCACCTGCGGACGCACACGGGCGAGCGACCATACATATGTGACCAGTGCGGACGTGGTTTCACTCAGAAGAACGACATGTTGAAACATCGGAGGACACACACGCTAGAGAGACCTTTCCCGTGCAACATCTGCGGCATGATGTTCAGCCAGAAGCGTGAGGTGGCAAAACATCACTTGATTCACATGCAACAGGTGGAAGAGCAGACGGAAGAAACAGTCGAGCCCCACACCGTTGTCATAACGACGAGCGACGACCAACTGATCCATAGCTTTTCTGCCGAGGTCATCGACGGCACGCAGACACTCTTGAACGTGTTCAATCAGTTTTAG
Protein Sequence
MFQETDCAMATETDGSLEIAEDDSMDPSYTLSMDPASLGLVMEEVHAGTEIPWEEEIGIITDEAICIENIFCRVCAEQAAELIPVFEEQGMELSLADKIRWHLPITISEDDKLPVKLCPACITRLNSCHDLANLCLESEAKLERLFNIDDATEFNESANEQKVTNSKSPSDHLIDGMKQFRKERMADNKYNNLSSGDNSNEDFETVYLEDAIDDDLKGQVLDVIIEPVGMESLPAGQWKTANLRVKMPKDFADCDTTLKSQIVGAIQDIMIEEDQSAKTKKNSSITRGNNKEWKCDICSHVAPRKSSLLVHQRRTHAKSFACSYCYKTFSNGVARRQHEVVHRPETIVDDDENSRQNDNAVPSFVCEICEVSFKRKKQLANHNLEHHTDVKQFKCSKCDKQYGSLTSLDIHHATHLSETAYLCDLCGKSFKHVSNLRSHKRSHLGDEKKNTQVCSVCSKGFRSRFHLKEHMNVHQNRTPYSCDICSKKFHKKIQLRQHGSVHLGLQPYKCNICGIRFNRRGNMTQHLKRHERQLKYTCKVCSAGFDRLGTLLQHRKAHTKDELDDAIYRQVAADDSVQEAYKCEICNKLLAKKETLMLHMRSHSGEKLFACEVCGKKLSNKGSLTYHMRSYHTGERPYSCQYCTDAFLTREACSVHERIHTGERPYFCTVCKMGFRCSSNLAQHVRVHTNVRNHQCEHCEKSFLRKGALTVHLRTHTGERPYICDQCGRGFTQKNDMLKHRRTHTLERPFPCNICGMMFSQKREVAKHHLIHMQQVEEQTEETVEPHTVVITTSDDQLIHSFSAEVIDGTQTLLNVFNQF

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00242452;
90% Identity
iTF_00242452;
80% Identity
-