Bris020770.1
Basic Information
- Insect
- Brachyptera risi
- Gene Symbol
- Ibtk
- Assembly
- GCA_964007535.1
- Location
- OZ023332.1:381016-406551[-]
Transcription Factor Domain
- TF Family
- BTB
- Domain
- zf-C2H2|ZBTB
- PFAM
- PF00651
- TF Group
- Zinc-Coordinating Group
- Description
- The BTB (for BR-C, ttk and bab) [6] or POZ (for Pox virus and Zinc finger) [1] domain is present near the N-terminus of a fraction of zinc finger (Pfam:PF00096) proteins and in proteins that contain the Pfam:PF01344 motif such as Kelch and a family of pox virus proteins. The BTB/POZ domain mediates homomeric dimerisation and in some instances heteromeric dimerisation [1]. The structure of the dimerised PLZF BTB/POZ domain has been solved and consists of a tightly intertwined homodimer. The central scaffolding of the protein is made up of a cluster of alpha-helices flanked by short beta-sheets at both the top and bottom of the molecule [2]. POZ domains from several zinc finger proteins have been shown to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes including N-CoR and SMRT [5, 3, 4]. The POZ or BTB domain is also known as BR-C/Ttk or ZiN.
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 4 4.6 1.9e+03 0.2 0.0 9 34 689 712 682 742 0.85 2 4 1.7e-11 6.8e-09 37.0 0.0 3 79 751 829 749 836 0.90 3 4 2.9e-15 1.2e-12 49.1 0.0 10 106 947 1048 941 1052 0.86 4 4 0.084 34 5.7 0.2 80 107 1054 1081 1049 1084 0.89
Sequence Information
- Coding Sequence
- ATGAGTGCGTTGAAGCTGGAGCCCGACTGCACGAGCCGGTGCCGCTCCTCGCAGCACGGGGACACGATGGTGGCGGCGCTGACTGTCCGCGGAGCCAGCGAGGCTGCCAAGGCGGCGTACCTGCGCGCGACCTGTTCCGCCTACTGTCAGGTTGTCGACACTGCGGGGCGCTCGGCACTCCACATGGCGGCCTCGACCGGCTGCGACAGCGTTGCCAGGTGGCTGGGGCAGCACAGGGAGTGCAACGTTAACCTCAAAGATCTGGAGTCGGGATATTCACCGCTGCACCGGAGCGTGTTGTACGGGCAGATACACGTGGCCACCAGTCTTATACAGCTGGGAGCGAACCCGCATGCCGTGGACCGCGACGATCTGACGGCGCTGGACCACGCGATGGTGGACCGCCCGGCTGCCGTGACCTTGAGTGCCGTGGACCCCTGCGAGGTGTACGTGTGGGGCACCAACACTAACTACACGCTCGGCATCGGCAACCAGGACAACCGGCCGCTTCCAGAACTCCTCGAGACATTCCGCAGACAGAACGTCAGCATCAAACAGGTGGCCATGCACAAGTTCCACTCGGTGTTTGTGTCGCACGACGGTCGTGCGTGGTCGTGCGGTCATGGCCAGGGCGGTCGGCTGGGCCTGGGCTCGGAGCAGGCCGTCCTGGCTCCGCGGCCGCTCAAGCTTGGAGTCTCCAAGAGTCTGGCTCCGGAGCTGTGCGTGGTGGCTAGCATCAGCAAGGATCACACCATCCTGCTCACGGAGGCCGGAACCGTGCTCACCTGCGGCCTCAACGCCCATCACCAGCTCGGGCTGGTCCCCCCGCCCCCGTACGTGACGGTGCCTGCCGTGGCCGTACGCTCGCTGAAGGTGGTGTCAGGGGTGTGCGCGTCGAGGTTCCACTCAGTGGTGTggggccctgggggcgtggccaCATTCGGCCTGCACGCTGGCCAGCTTGGACACCCCCGGTCTGCCGACAAGACCGTCCTCAAGCCCAAGGTTGTGGTGGCCCTGGATCTCTCCAACGCAACCGTCACGCAGGTTGCCTCCAACGACGGAGCGATCGTCGTGGTAACGGACAGGGGCCATGTGTACGTGTTGCACGAGTACCAGTGCCGTCGCATCGCGTCGCGCCAGACTGACGTGGCCAAGGTCACGGTGGTCGGAGGTCACCTGGACTCACGCCTCGAGAGGGACCTGTTGGTGGACCGCGGGGGGGACGCTCTCAAGGTCGCCCTGCTCACCACTGCCGGCAAGCTGTTCATCTGGCAGGAGACCTCCCCGCAGCTCATCAGGTGTGTGTTCACCGTGAACCGCCTGTTGCTGTTGAGAGACGTGGTGATGACGCGGAACCACCTGCTGTTCGTGACGCGTGACGGAGAGGCTTTCACCGGCGAGATCAAGCCTAAGAGACCCAAGAGACTGGTGTGTGTTCACCGTGAACCGCCTGTTGCTGTTGAGAGACGTGGTGATGACGCGGAACCACCTGCTGTTCGTGACGCGTGTGTGTTCACCGTGAACCGCCTGTTGCTGTTGAGAGACGTGGTGATGACGCGGAACCACCTGCTGTTCGTGACGCGTGACGGAGAGGCTTTCACCGGCGAGATCAAGCCCAAGAAACCCGAGAGACTGGTGGCGTTCTCGGAGCTGACCTTGAACTGTTGTTTGGCCGCAGGTGTGTGTTCACCGTGTGTGTTCACCGTGAACCGCCTGTTGCTGTTGAGAGACGTGGTGATGACGCGGAACCACCTGCTGTTCGTGACGCGTGACGGAGAGGCTTTCACCGGCGAGATCAAGCCTAAGAGACCCAAGAGACTGGTGTGTGTTCACCGTGAACCGCCTGTTGCTGTTGAGAGACGTGGTGATGACGCGGAACCACCTGCTGTTCGTGACGCGTGTGTGTTCACCGTGAACCGCCTGTTGCTGTTGAGAGACGTGGTGATGACGCGGAACCACCTGCTGTTCGTGACGCGTGACGGAGAGGCTTTCACCGGCGAGATCAAGCCCAAGAAACCCAAGAGACTGGCGCTCGATCAGAGACCTCAGAGCCGGGCCCTGGAGACGGCTGAttgcgagGTGATTGCAGCGACGCGATTGGCCCACGCACACCGTGCCGTCAGCGCCTGTTCAGACCCCAAGGGCCGGAACTTTGCCCTGATCCAGGCGCACCCCAAGCAGGCGCTGTTGGACGTGCCGGAGGTGGAGACGACGGCCATGAGGGAGCACATGAGGAGCTTGCTGGACGACGCCGATGAGCACGACTCTATACACGACGTCGTCTTCACGGTCGGTCTGAGAAAGTTTGCTTCTCACAAGTTCATAATCACGTCACGAAACGAATGCCTTGGCAAGCTGATCGCAGACCGAGTGGCCGACTCTCCTGCCGACGACAACGTAGTCAAGGTTGCAGTTCAAGACATCCAGCCCGACGTCTTTGAACAGATCCTCCAGTACATCTACACCAACGAGTGCGACATGATGACTCTCGGCAGATGTCCCGCCATAACACCCGACACAAGCCCTTCCATCGTCAACGGGCACTCCGAGATCGTCCGAGAAGACCTGTCTGCCGAACAACGCCAGAATATGTCTGCTTTCGCTGTTTACTCGTCGGAAAACAGGAAGACCAAGAAGAACAAGGTGTCGACACCGAACGTGTCGAGCGAGTGGGACCCGGTGAGGGTCGTGCAGAGGTCAGCCAGGAGGTTAAACATGCAAGAGCTGTGCACCGAACTGGACGGGTTTGCTCACGAGGACGGTTTTATCGTCCCGAAGAACAAGCGTGGAAAGCCGACGGCACGACCGTCGTGGCACCGAACCGACGACGATCCGCTACACGACGTGACGATCCGCAGCGCTGACGGGCGCCAGATGGGAGCGCACAAGTGCGTGCTAGCGGCGCGGCTCGAGTACTTCCACAGCATGCTGAGCCAGGGGTGGAGCGAGACGTCGGGCGGCCGGAACGCCCTGAGCTTGGCGCTGCCCTACGAGGTGCTCCGGATACTGCTGGACTTCCTGTACGAGGACGAGGTGGAGGCGGTGCGGGGGTCGGAGGACGTGGGGCTGTGGAGCAACGTGCTGGTGGTGGCCGATCAGCTGTTTGTGCAGCGGCTGAAGGAGCAGTGCGAGGTGGCGCTAGCCGGCCTGCTCACGCTGAAGAACGTGGCCGAGATGCTACAGACAGCTGACACGTACAACGCTCCGCAGCTCAAGGCCTGCTGCATGCAGTACGTCTGTCTCAACCTCGGGGCCGTGCTCGAGTCAAGGTGCTTGGAGAACGTGAGCCGCGAGGTGCTGGCCAGACTCAGTCTGTATTACCGCGATCTCAACCCTGCCGTCAGCAAGCGCCTCATCGCTCCGCTCTCGTTCGCTCCGACCGTACACACCCTCGGCTCCGCATTGCAAGACAATCCGTTCACGTTCGACCAGGAAGATTCCATCATCGTCGCTGACAACATCGTTAAGAGAGCGTTGAAACAAGCCAAGAAGAAAACAAGGGTTCGTAAGAACAGCAACGAGGCGTCTAAAACTGTCCGCACGCGTGTCGAGTCAACGAGTTCAATCGTATCCGAAGACTTGGACCAAACTGTCGAGTCGTTCGGCTTCAACGACATTGTGGAGAAGTCGCCCACGAATGAAGATATCTCGGCTTCGGTCAAAGAAAATACTGAGAAAAACTCACAGTGGGTTAAAATTCCTGCTAGTAGCAAACAGCAGAAAATTGTCCAAGCTCGTCTCAAAGCCATCAACATGTCGAATGACTCGTCTTTCATCGCTGAATCGAGCCGAGAATCGTTCACCAGACTCACTCGGAACTCTCCAAGTCCCGTTCCGGCTCCGGCAGCCGCTCCGGTCCCGAACCCACTCCCGGAACGAGTTTCCCCGTTGGACAAAGCCATGATACCGACAACAGGGATAACATCGCTGGACTTCCCGGACCTGTGCTCCCCTCCCAACAGCCAACACAAGCTCGGCACGCACAGCAAGACGGACAAGGCAGTTCCAAAGAAGGTCGTTAAGATATCTCAGAAGCAACGCAAGCGTCTGACGTCAATCAGCGATATTGGCCTGATGGCCGACCACTTGGACGCCATCAACCAGTCCCCGCCGCCCCCACCCCCGGCCTGGGGGCGGCACAGCCCGGAGGCGGGGGCGGAGAGTGGCTCGCTGGTGGACATCATCCGACAGGAGCTGCGTCAGGTGAGGATCAGCCCGGCGTTGCCCGTGGAACGTGTGCCCGTGGAACGTGTGCCGGCGAGGGTGGCCGCCCTCAACCCGTGGTCCAAGGTCGCAACGCCCCAAGTGGTCTCGCCCGGACAGAAGCCGGCCGTCAGCTTCACGGCGATCGTTGCCGACGAGAAGAAACAGAAAGACAACTTGACAAAGATGCTGTCCAAGCCACTCGAACTAACCCAGATCGAAGACAAGGCCATCTCGGACCTGCTACAGTTCTACAACGCCAGCGGGGCCACGGAGGAGAGGATCACCGTGCAACGCGTCAACGCCGGCCCCATTGCCGTCCCCACCTGGATAACCAATCACTAG
- Protein Sequence
- MSALKLEPDCTSRCRSSQHGDTMVAALTVRGASEAAKAAYLRATCSAYCQVVDTAGRSALHMAASTGCDSVARWLGQHRECNVNLKDLESGYSPLHRSVLYGQIHVATSLIQLGANPHAVDRDDLTALDHAMVDRPAAVTLSAVDPCEVYVWGTNTNYTLGIGNQDNRPLPELLETFRRQNVSIKQVAMHKFHSVFVSHDGRAWSCGHGQGGRLGLGSEQAVLAPRPLKLGVSKSLAPELCVVASISKDHTILLTEAGTVLTCGLNAHHQLGLVPPPPYVTVPAVAVRSLKVVSGVCASRFHSVVWGPGGVATFGLHAGQLGHPRSADKTVLKPKVVVALDLSNATVTQVASNDGAIVVVTDRGHVYVLHEYQCRRIASRQTDVAKVTVVGGHLDSRLERDLLVDRGGDALKVALLTTAGKLFIWQETSPQLIRCVFTVNRLLLLRDVVMTRNHLLFVTRDGEAFTGEIKPKRPKRLVCVHREPPVAVERRGDDAEPPAVRDACVFTVNRLLLLRDVVMTRNHLLFVTRDGEAFTGEIKPKKPERLVAFSELTLNCCLAAGVCSPCVFTVNRLLLLRDVVMTRNHLLFVTRDGEAFTGEIKPKRPKRLVCVHREPPVAVERRGDDAEPPAVRDACVFTVNRLLLLRDVVMTRNHLLFVTRDGEAFTGEIKPKKPKRLALDQRPQSRALETADCEVIAATRLAHAHRAVSACSDPKGRNFALIQAHPKQALLDVPEVETTAMREHMRSLLDDADEHDSIHDVVFTVGLRKFASHKFIITSRNECLGKLIADRVADSPADDNVVKVAVQDIQPDVFEQILQYIYTNECDMMTLGRCPAITPDTSPSIVNGHSEIVREDLSAEQRQNMSAFAVYSSENRKTKKNKVSTPNVSSEWDPVRVVQRSARRLNMQELCTELDGFAHEDGFIVPKNKRGKPTARPSWHRTDDDPLHDVTIRSADGRQMGAHKCVLAARLEYFHSMLSQGWSETSGGRNALSLALPYEVLRILLDFLYEDEVEAVRGSEDVGLWSNVLVVADQLFVQRLKEQCEVALAGLLTLKNVAEMLQTADTYNAPQLKACCMQYVCLNLGAVLESRCLENVSREVLARLSLYYRDLNPAVSKRLIAPLSFAPTVHTLGSALQDNPFTFDQEDSIIVADNIVKRALKQAKKKTRVRKNSNEASKTVRTRVESTSSIVSEDLDQTVESFGFNDIVEKSPTNEDISASVKENTEKNSQWVKIPASSKQQKIVQARLKAINMSNDSSFIAESSRESFTRLTRNSPSPVPAPAAAPVPNPLPERVSPLDKAMIPTTGITSLDFPDLCSPPNSQHKLGTHSKTDKAVPKKVVKISQKQRKRLTSISDIGLMADHLDAINQSPPPPPPAWGRHSPEAGAESGSLVDIIRQELRQVRISPALPVERVPVERVPARVAALNPWSKVATPQVVSPGQKPAVSFTAIVADEKKQKDNLTKMLSKPLELTQIEDKAISDLLQFYNASGATEERITVQRVNAGPIAVPTWITNH
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -